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세탁소를 운영하는 부부에서 동시에 발생한 담낭암 담낭암과 벤젠과의 연관성
심광연 ( Kwang Yeun Shim ),차상우 ( Sang Woo Cha ),엄욱현 ( Wook Hyun Um ),전창균 ( Chang Gyun Chun ),정승원 ( Soung Won Jeong ),장재영 ( Jae Young Jang ),조영덕 ( Young Deok Cho ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2
Gallbladder (GB) cancer occurs predominately as a biliary tract malignant tumor. It generally has a very poor prognosis, and early detection is often difficult. A variety of carcinogens have been implicated as an important cause for GB cancer. Benzene is a well-known carcinogen for hematologic malignancy, and its casual relationship with GB cancer has been suggested. We report a case of two patients who had operated a laundry cleaning facility together and later simultaneously got GB cancer after prolonged benzene exposure.
급성 췌장염 후 악화된 산역류 연관성 미만성 식도 경련
은수훈 ( Soo Hoon Eun ),이준성 ( Joon Seong Lee ),전창균 ( Chang Gyun Chun ),김연수 ( Yeon Soo Kim ),주현수 ( Hyun Soo Joo ),정현구 ( Hyun Ku Jung ),김경민 ( Kyung Min Kim ),정인섭 ( In Seop Jung ),고봉민 ( Bong Min Ko ),홍수진 ( 대한소화기기능성질환·운동학회 2007 Journal of Neurogastroenterology and Motility (JNM Vol.13 No.1
Diffuse esophageal spasm (DES) is a typical motility disorder of the esophagus thats manifested by episodic chest pain and dysphagia. Visceral hypersensitivity is considered to be an important pathophysiological mechanism in the development of noncardiac chest pain, the same as for functional gastrointestinal disorders. Recent studies have revealed that descending facilitation from the rostral ventromedial medulla maintains visceral pain in a model of experimental pancreatitis. We report here on a 24-year old male who suffered from retrosternal chest pain and dysphagia, and this was aggravated after acute pancreatitis. The initial endoscopic examination revealed reflux esophagitis. After 11 months, esophageal manometry showed the typical findings of diffuse esophageal spasm, while the endoscopic examination and 24 hr pH metry failed to reveal acid reflux. We performed endoscopic botulinum toxin injection that resulted in relieving his symptoms along with improved results on the balloon provocation test. We present here a case of aggravated reflux-associated DES after acute pancreatitis, along with a review of the literature. (Kor J Neurogastroenterol Motil 2007;13:76-80)
관상동맥 성형술에서 일반 스텐트와 약물방출 스텐트 사용에 따른 혈청 sCD40L 및 neopterin의 농도변화
윤진아,박승훈,류지원,전창균,홍중락,방덕원,현민수,김성구,권영주 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1
Drug-eluting stents(DES) had decreased the frequency of coronary restenosis. We therefore hypothesized that DES would be associated with reductions in serum levels of soluble CD40L and neopterin after percutaneous coronary intervention(PCI). We studied 40 patients who underwent PCI and who had repeated angiograms at 6-month follow-up. Plasma sCD40L and neopterin were measured before and 6-munth after PCI. Patients treated with DESs(n=20) did not differ in baseline characteristics, sex, age and risk factors. Both DES and BMS(bare metal stents) groups did not show difference between before and after PCI in serum levels of sCD40L and neopterm (mean 2.72±4.32ng/mL vs 1.26±1.45ng/mL, p = 0.141 in BMS and 4.05±5.22ng/mL vs 2.73±4.34ng/mL, p = 0.411 in DES for sCD40L, mean 6.69±5.66nmol/L vs 5.38±4.52nmol/L, p = 0.079 in BMS and 6.84±6.93nmol/L vs 7.41±6.41nmol/L, p = 0.715 in DES for neopterin). Patients treated with DES did not show diffrence in changes of sCD40L and neopterin (mean -1.31±7.00ng/mL vs -1.451±4.23ng/mL, p = 0.940 for sCD40L, 0.578±6.99 nmol/L vs -1.31±3.16nmol/L, p = 0.278 for neopterin). Serum levels of sCD40L and neopterin were not associated with late restenosis after PCI. Also both of sCD40L and neoptehn did not differ by DES use.
약물 방출 스텐트 삽입 후 반복적으로 발생한 아급성 스텐트 혈전증 1예
심윤숙,최은숙,노미오,전창균,정철호,이승환,조윤행,이내희 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2
Drug-eluting stents (DES) have been proved to reduce the restenosis rates and the need for repeated revascularization. But the concerns about stent thrombosis (ST) have been raised because ST is a serious complication of DES implantation. Repeated ST is rare. We report a case of recurrent ST after DES implantation. 경피적 관상 동맥 중재술 후 반복적으로 발생한 아급성 스텐트 혈전증의 환자애서 관상 동맥 우회로술로 회복된증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이 다.