심혈관 CT 검사 시 적응식 통계적 반복 재구성법(ASIR)에 대한 유용성

장현철(Hyun Chul Jang),조용근(Yong Geun Cho),오용운(Yong Woon OH),김진배(Jin Bae Kim),조인완(In Wan Cho),구상진(Sang Jin Gu),유병헌(Byeong Heon Yoo) 대한CT영상기술학회 2010 대한CT영상기술학회지 Vol.12 No.2

Purpose The goals of this study was to evaluate effect of reduced radiation dose, change of CT noise, and proper amount of ASIR under assessing image quality with different ASIR amounts during cardiovascular CT examinations. Materials and methods 15 patients who had undergone routine cardiac CT for evaluation of bean problem were enrolled and all examinations were performed on a 64-MDCT scanner (Light-Speed VCT XTe, GE Healthcare, Milwaukee, USA). The GE performance evaluation phantom was scanned triple and noise were measured at center(directions of 6 o’clock) and periphery (directions of 9, 12, 3 o’clock) of phantom image under fixed 100 kVp and during changing of ASIR 0~100%. The two radiologists estimated me subjective image qualities of right coronary artery(RCA), left circumflex artery(LCX), left anterior descending artery(LAD) in reconstructed four chamber images. To assess radiation dose, CTDIvols recorded from applied ASIR man non-applied ASIR were compared and analyzed. Results In applied ASIR to image in 10 % increments (0~100%), CT noise of center(directions of 6 o’clock) and periphery(directions of 9, 12, 3 o’clock) of phantom decreased in 9.7%~49.5%, 9.8%~52.1%, 9.6%~48.9%, 9.7%~51.1%. Observer A and B estimated image quality respectively as follows: 15 and 15 patients until 60% ASIR, 13 and 13 patients until 70% ASIR, 12 and 8 patients until 80% ASIR, 8 and 6 patients until 90% ASIR, 7 and 6 patients at 100% ASIR In assessing radiation dose, CIDIvol recorded from 60% ASIR decreased in 46.9% (21.11 mGy) than non-applied ASIR(39.73 mGy) Conclusion 60% ASIR helps reduce radiation dose and acquire consistent image quality without spoiling quality.

전자거래 디렉토리 서비스를 위한 자동 색인기 및 검색엔진 개발

장현철(Hyun-Chul Jang),신동욱(Dong-Wook Shin),이재선(Je-Seon Lee),함호상(Ho-Sang Ham) 한국정보과학회 1997 한국정보과학회 학술발표논문집 Vol.24 No.2Ⅱ

인터네트의 발달과 전자거래의 중요성에 대한 인식이 커짐에 따라 전자거래에서의 지불 방법, 전자 화폐 그리고 보안에 대한 연구가 활발히 이루어지고 있다. 전자거래 서비스를 효과적으로 하기 위해서는 여러 가지 서비스 및 기능이 제공되어야 하는데 이중에서, 사용자가 원하는 상품에 대한 정보를 손쉽게 찾도록 하는 디렉토리 서비스가 필요하다. 이 디렉토리 서비스에서는 인터네트 상에서 전자거래에 관련된 정보를 수집하고 수집된 정보를 색인하며 검색할 수 있는 일련의 과정이 제공되어야 한다. 본 논문에서는 전자거래 관련 디렉토리 서비스를 위하여 전자거래 관련 문서를 수집하고 색인하여 사용자에게 상품에 대한 가격 및 상품 정보를 효과적으로 검색할 수 있는 방법을 제시한다.

양극산화 인가전압에 따른 장범위 규칙 다공성 알루미나 멤브레인의 제조

장현철 ( Hyun Chul Jang ),최정미 ( Jung Mi Choi ),안기태 ( Ki Tae An ),이내성 ( Nae Sung Lee ),박윤선 ( Yun Sun Park ),석중현 ( Jung Hyun Sok ) 대한금속재료학회 ( 구 대한금속학회 ) 2012 대한금속·재료학회지 Vol.50 No.1

Studying the long-range ordering of nanopores on the anodic aluminum oxide (AAO) membranes under a hard anodization (HA) approach is crucial in producing well-aligned nanopores on the AAO membranes. Electro-polishing in a mixture of ethanol and perchloric acid for 5 min removed marks formed by rolling and produced flat surfaces on aluminum substrates. The AAO was formed by the first HA process, providing seeds for the subsequent production of uniform AAO nanopores. The second HA process carried out on the seeds produced well-aligned, uniform AAO nanopores. The AAO nanopores, varying in size and shape, were observed with voltages applied for HA. This study provides a route for controlling the size and shape of AAO nanopores by changing the applied voltages.

천패모(川貝母)와 절패모(浙貝母)의 처방활용(處方活用)에 관한 고찰(考察) - 동의보감(東醫寶鑑)과 방약합편(方藥合編)을 중심으로 -

김안나,장현철,오용택,배순희,김상균,김진현,김철,송미영,Kim, An-Na,Jang, Hyun-Chul,Oh, Yong-Taek,Bae, Soon-Hee,Kim, Sang-Kyun,Kim, Jin-Hyun,Kim, Chul,Song, Mi-Young 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.2

In this study, we considered the usecase of formulas containing either Fritillaria Bulb (川貝母) or Fritillaria Thunbergii Bulb (浙貝母). These two medicinal materials are distinguished in the Korea Pharmacopoeia and circulating the market separately. But only term "貝母" is traditionally written for describing formulas, and the proper material will have to be determined by a subjective point of view. So, we have comparatively studied the nature, flavor, meridian entry, effect and indication of two materials first. Then we have chosen 54 formulas that "貝母" was used as a primary material from the Donguibogam and the Bangyachappyun, and we have compared effects, indications of two materials and indication of 54 formulas. Finally, we have suggested proper materials for each formula by referring the results above and sentences, which is explaining formulas and the roles of materials in the combination for treatment. The analysis showed that Fritillaria Bulb is proper to 15 formulas, Fritillaria Thunbergii Bulb is proper to 31 ones. This number is 85.2% of 54 formulas and this result shows that we need to distinguish between two materials for "貝母" in the formulas from old traditional literature. For the rest 8 formulas (14.8%), we could not analyze which material is proper or not.

p38 MAPK을 이용한 항염증 효능 규명 프로토타입 개발

김철(Chul Kim),예상준(Sang-jun Yae),남기엽(Ky-youb Nam),김상균(Sang-kyun Kim),장현철(Hyun-chul Jang),김진현(Jin-hyun Kim),김영은(Young-eun Kim),송미영(Mi-young Song) 한국한의학연구원 2011 한국한의학연구원논문집 Vol.17 No.3

Objectives : The purpose of this study was to develop a simulator which can analyze the anti-inflammatory effects of medical herbs based on e-cell concerning p38 MAPK signal pathway. Methods : We collected data concerning medical herbs with anti-inflammatory effects and the active compounds to provide as a fundamental databse and to validate the newly developed algorithm. At this time, we used the target database as pubmed and gathered the data by data mining tool, pathwaystudio. Also we have developed the web-based search system for confirming database related to anti-inflammation. We researched the mechanism of actions of proteins in p38 MAPK signal pathway when active compound has been inserted into the network. We reduced total network into TAK-MKK3-p38 and made the two types of mathematical model about active compounds' interaction. Results & Conclusion : We constructed the database which have 69 cases of medical herbs, 71 cases of active compounds, about 8,000 cases of URL(Uniform Resource Locator) related to papers and reports. We designed the ordinary differential equations for response of TAK, MKK3, p38 in e-cell's cytosol and nucleus. We used this formular as measure whether an active compound of medicinal plants which is inputted by an user would have an anti-inflammation effects. We developed the visualization program which could show the change of concentration over time.

학술논문의 참고문헌 자동매핑 방법에 관한 연구

한정민,장현철,김진현,예상준,김상균,김철,송미영,Han, Jeong-Min,Jang, Hyun-Chul,Kim, Jin-Hyun,Yea, Sang-Jun,Kim, Sang-Kyun,Kim, Chul,Song, Mi-Young 한국과학기술정보연구원 과학기술정보센터 2010 Journal of Information Science Theory and Practice Vol.41 No.3

학문의 발전과 주제의 다양화로 인하여 각계의 연구자들은 자신에게 필요한 정보를 정확하게 찾을 필요성이 커지고 있다. 그리하여 본 논문에서는 효율적인 참고문헌 추출 방법으로 중복된 참고문헌을 비교 분석하여 자동으로 매핑해주는 시스템을 구축하고, 한의학 사전을 통한 한자의 오타를 교정할 수 있는 방법을 연구하였다. 이러한 방법을 적용함으로써 참고문헌의 중복입력과 한자오류를 개선할 수 있었다. With the advanced learning and the diversity of topics, researchers on each area keenly feel the need of precise and a quick discovery of required information at any time. This study presents a way of constructing the automatic mapping system that can compare and analyze duplicated data and that describes the result by building an effective reference extraction method and another way of correcting the wrong form of used Chinese characters with Traditional Korean Medicine dictionary. With this innovation, data duplication on references and Chinese characters errors can be fixed. Under the situation that a number of references of newly published papers that can continuously be extracted.

웹 접근성을 고려한 전통의학정보포털 설계 및 구현

한정민,장현철,김진현,예상준,김상균,김철,송미영,Han, Jeong-Min,Jang, Hyun-Chul,Kim, Jin-Hyun,Yea, Sang-Jun,Kim, Sang-Kyun,Kim, Chul,Song, Mi-Young 한국과학기술정보연구원 과학기술정보센터 2010 Journal of Information Science Theory and Practice Vol.41 No.4

본 논문에서는 국내에서 유일하게 한의학 학술논문 및 한의학 연구정보를 제공하는 오아시스(Oriental Medicine Advanced Searching Integrated System)를 대상으로 국가에서 정한 [웹 접근성 국가표준]을 어느 정도 반영하고 있는지 평가해 보고, 웹 접근 취약성을 분석하여 해결방법을 모색하였다. 웹 접근성 평가항목으로는 웹 콘텐츠를 쉽게 인식할 수 있는 정도를 평가하는 인식의 용이성(Perceivable), 웹 콘텐츠를 누구나 쉽게 사용할 수 있는지를 평가하는 운용의 용이성(Operable), 콘텐츠 구성에 대해 쉽게 이해할 수 있도록 제어하고 있는지를 평가요소로 하는 이해의 용이성(Understandable), 웹브라우저의 종류나 버전에 관계없이 정상적으로 동작하는지를 평가하는 기술의 진보성(Robust)으로 구분하여 평가하였다. 평가된 결과를 기준으로 문제점을 분석하고 이를 토대로 장애인의 웹 접근성을 고려한 오아시스를 설계하고 구현하였다. 웹 취약성을 수정하여 재구축한 오아시스는 한의학 연구를 하는 청각, 시각 장애인들에게 일반인들과 동등한 웹 접근 기회를 부여해 줌으로써 장애인들의 한의학 지식습득에 많은 도움을 줄 것으로 기대된다. This study shows evaluation of how much OASIS meets "the korean web content accessibility guidelines" and analysis of some of the accessibility problems and their solutions in OASIS(Oriental Medicine Advanced Searching Integrated System) which is the only web site that offers papers and project information related to Traditional Medicine in Korea. The evaluation criteria to determine if OASIS is accessible is classified into four sub items; Perceivable - if information and user interface components is presentable to users in ways they can perceive, Operable - if user interface components and navigation are operable, Understandable - if information and the operation of user interface are understandable, Robust - if content is robust enough that it can be interpreted reliably by a wide variety of user agents, including assistive technologies. Based on the measured results, OASIS has just been redesigned and implemented in more accessible and effective way. OASIS that improves web accessibility for the disabled is expected to help them study oriental medicine more easily and conveniently by providing equal access and equal opportunity to use the web.

한.양방 협진 정보시스템 구축방안 연구

예상준,장현철,김철,김진현,김상균,송미영,Yea, Sang-Jun,Jang, Hyun-Chul,Kim, Chul,Kim, Jin-Hyun,Kim, Sang-Kyun,Song, Mi-Young 대한예방한의학회 2009 대한예방한의학회지 Vol.13 No.3

Background : Recently, Medical Act was amended to encourage the induction of combined treatment between Oriental Medicine doctors and Western doctors. As yet, the information infra for combined treatment has not been studied. Objectives : This study aimed to design the architecture of information system for combined treatment of the Oriental and the Western Medicine. Methods : First, we defined the information of combined treatment through the analysis of research trends from the inside and outside of the country. Because the data compatibility is very important, the definition of information must be ahead of anything else. Second, we designed the architecture of information system based on the prior definition. Results : We classified the information for combined treatment by subject such as law, clinic, research, manpower, facilities, and education. In this paper information system examined in three aspects. First the infra layer is organized as hardware, netware, and security. Second is data warehouse layer for the storing, filtering, and extraction of data. Third is service layer which is related to data transmission. And Finally all information for combined treatment is provided through the portal system for medical consumer, political planner, and R&D researcher. Conclusion : In this paper, we studied the essential factors of combined treatment information in the view point of information system. But the detailed design and implementation of information system must be followed to effect this results.

UMLS내 전통의학 용어에 대한 고찰

김진현 ( Jin Hyun Kim ),김철 ( Chul Kim ),장현철 ( Hyun Chul Jang ),전병욱 ( Byoung Uk Jeon ),예상준 ( Sang Jun Yea ),김상균 ( Sang Kyun Kim ),송미영 ( Mi Young Song ) 대한한의학원전학회(구 대한원전의사학회) 2010 대한한의학원전학회지 Vol.23 No.6

Objective This is a previous study for including traditional Korean medical terms into the UMLS(The Unified Medical Language System) and achieving the interoperability between various medical systems. Method First, the traditional medical terms were divided into 4 categories: basic theory, acupuncture, herb and formulae. And then, searching these terms through metathesaurus in UMLSKS(UMLS Knowledge Source Server), terminology information was investigated and analyzed. Results In the case of TM title, traditional Korean medicine was categorized as different semantic type from Traditional medicine, Traditional Chinese medicine and Kampo medicine. Acupuncture points were described only as abbreviation and herbs were conceptualized inconsistently, as some belonged to scientific name and some belonged to Chinese pronunciation. Formulaes are described as Chinese, Japanese and Korean pronunciations. Conclusions More research is needed on diagnosis/disease terms and semantic types for the unique concepts in traditional Korean medicine in order to including the international standard.

한의치료를 받은 산모의 산후 6주간 증상에 대한 전향적 관찰 연구

김평화,김안나,장현철,이은희,Kim, Pyung-Wha,Kim, An-Na,Jang, Hyun-Chul,Lee, Eun-Hee 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.4

Objectives: This study aims to investigate the changes of women's postpartum symptoms, including their weights, edema index and quality of life (QOL) over the first six weeks after childbirth. Methods: The study participants were 31 postpartum women treated in the Dept. of Obstetrics & Gynecology, at Woo-Suk University Korean Medicine Hospital, from May 20th to August 5th, 2016. In the first 2 weeks of the postpartum period, the main data collection method was to interview each patient and write down all of their complaints, and additionally referring to each participant's PHR (Personal Health Records). At the 3rd, 4th, 5th and 6th week, the researcher interviewed participants by phone once a week. The participants' weight, edema index (ECW/TBW) and the quality of life (by EQ-VAS) were measured at 1st and 2nd week after childbirth. And, EQ-VAS was assessed once more at the 6th week after childbirth. As a last step, the participants responded to a survey on satisfaction regarding their postpartum care with Korean Medicine. Results: 1. In the 1st one week after childbirth, edema was the most frequent complaint. It was about joint pain of the upper limbs in the 2nd and 3rd weeks, sweating in the 4th week, and joint pain of the upper limbs in the 5th and the 6th weeks. 2. In the 1st two weeks of the postpartum period, the weight of the participants decreased from $66.33{\pm}9.30kg$ to $62.60{\pm}8.92kg$ (p<0.001) and the edema index ECW/TBW decreased from $0.399{\pm}0.010$ to $0.385{\pm}0.0 4$ (p<0.001). The EQ-VAS significantly improved from $61.77{\pm}17.72$ to $73.51{\pm}14.67$ (p<0.001). In the last 4-weeks of the postpartum period, the EQ-VAS decreased from $74.30{\pm}14.25$ to $73.63{\pm}13.35$, but this difference was not statistically significant (p=0.749). 3. Regarding the satisfaction with postpartum care with Korean Medicine, 60% of the participants responded that it was 'Excellent' and 40% said it was 'Good'. Conclusion: Over the entire postpartum period, the most frequent complaints were about musculoskeletal symptoms. Postpartum care with Korean Medicine treatments in the early postpartum period improves various postpartum symptoms and the quality of life for postpartum women.