한국인 대학생군 대상의 청.장년층 대사이상증후군 위험성 평가

정재훈,이보름,임성진,장제관,이명구,이종길,임성실,Chung, Jae-Hun,Lee, Bo-Reum,Lim, Sung-Jin,Jang, Je-Kwan,Lee, Myung-Koo,Lee, Chong-Kil,Lim, Sung-Cil 대한약학회 2009 약학회지 Vol.53 No.1

Metabolic syndrome, defined as the clustering of several metabolic disorders including obesity (waist circumference ${\geq}90$ if male or ${\geq}80$ if female, cm), dyslipidemia ($TG{\geq}150$ or HDL-C<40 if male or <50 if female, mg/dl), hypertension ($BP{\geq}130/85mmHg$) and hyperglycemia (fasting plasma $glucose{\geq}110mg/dl$), increases the cardiovascular risk of the general population. Recently, risk of this syndrome arises in young adults world widely. Therefore, we randomly selected and evaluated the risk of metabolic syndrome of total 43 people (group I-22, group II-21) for 2 years. Group I was 22 peoples (15 males, 7 females) with age of 22 thru 35 year old (average 28 year old) and group II was 21 people (19 male, 2 female) with age of 22 thur 32 years old (average 24 year old) in Cheongju area from March 1st thru 30th of 2008 in Cheongju area from September 1st thru 30th of 2007 in order to find out how serious this phenomenon is in young adult of Korea. 13.95% (n=7) of total people has a metabolic syndrome by NCEP/ATPIII definition among this group (group I-6, group II-1). Those of 6 have 3 or over risk factor for metabolic syndrome such as obesity, hypertension, fasting blood glucose and hypetriglyceridemia at the same time (group I-5, group II-1). Group I have more risk factor because of more higher age than group II. Therefore we need aggressively to monitor and provide them for early diagnosis, educational programs and assistance for lifestyle changes in order to prevent metabolic syndrome among young adults.

가정에서 미사용된 약물처리에 대한 평가

연정화,이보름,이명구,이종길,장제관,서광훈,오민아,한옥연,임성실,Yeon, Jeong-Hwa,Lee, Bo-Reum,Lee, Myung-Koo,Lee, Chong-Kil,Jang, Je-Kwan,Suh, Kwang-Hoon,Oh, Min-A,Han, Ok-Yeon,Lim, Sung-Cil 대한약학회 2009 약학회지 Vol.53 No.2

Most of families in Korea keep some medicines that has been expired or not been used for a long time, and these medicines could be causing environmental or social problems. Currently many people concerned about their health and therefore show a tendency to visit many health facilities. It eventually brings to remain more medication in home The aim of this study is to determine the drug waste minimization and drug disposal in Korean home and provide the proper guideline for them. This study were performed by visiting total randomly selected 140 homes at the Seoul area from July 23rd, 2008 to July 31st, 2008 by questionnaire. This survey comprised total 6 parts and total 22 questions. In results, 77 (55.0%) among 140 families answered to this survey. 89.6% of families keep unused medicine in the home. Most were tablet (66.3%) and syrup (19.2%) dosage type. They usually kept the unused medicine in the room (41.6%) or no certain place. 76.6% families reused the medicine and used for themselves. The reason for reuse is similar symptoms by their decision. The reason for medicine was left over is not following the prescription's direction (31.3%). They mostly dispose the unused medications by throwing into a trash can (71.4%). In conclusion, many families keeps unused medication and it could cause health and environmental problems.

이비인후과 영역에서 일반의와 전문의에 의한 외래처방전의 비교 평가

민현성(Hyun Seong Min),송태범(Tae Beom Song,)이명구(Myung Koo Lee),장제관(Je Kwan Jang),이종길(Chong Kil Lee),임성실(Sung Cil Lim) 대한약학회 2010 약학회지 Vol.54 No.4

As people are easy to access the National Health Insurance, medical health service has been increased. It contributed to extend human’s average life expectancy and to get better health care. But also increased unnecessary health service or inappropriate drug use. Therefore, DUR (Drug Use Review) is needed to induce appropriate drug use. The purpose of this study is to evaluate outpatient prescriptions by General Practitioner (GP) and Specialized Practitioner, especially indication for ENT referral including common cold which is the frequent indications that have patient see doctor. This study was reviewed retrospectively prescriptions for ENT referral collected at the A pharmacy for ENT Clinic in Cheong-Ju, B pharmacy for GP Clinic in BoEun from Feb 2nd, 2009 to Feb 28th, 2009. Each pharmacy located closed to the each enrolled clinic. The numbers of collected prescriptions were each A pharmacy (n=2501), B pharmacy (n=1343). This study was classified Drug Related Problems (DRPs) those prescriptions had as total 6 groups according to following 6 categories; 1) Unnecessary Drug, 2) Wrong Drug, 3) Low Dose, 4) Overdose, 5) Wrong Instruction, 6) Wrong Combination. In results, Specialized Practitioner’s prescriptions had more DRPs than General Practitioner’s prescriptions (ENT 155.34% vs GP 130.01%). In detail, Specialized Practitioner’s prescriptions had more DRPs in Low Dose (ENT 16.95% vs GP 4.77%), Overdose (ENT 6.72% vs G.P 5.51%), Wrong Instruction (ENT 7.91% vs GP 5.81%), Wrong Combination (ENT 29.31% vs GP 25.09%). These DRPs would be caused from lack of consideration for dosage and drug interaction. General Practitioner’s prescriptions had more DRPs in Unnecessary Drug (ENT 70.37% vs GP 78.85%), Wrong drug (ENT 4.12% vs GP 9.98%). These DRPs would be associated with drug selection. This study was assumed that Specialized Practitioner is better prescriber than General Practitioner because Specialized Practitioner complete additional intern and residency training. But, Specialized Practitioner is not always better prescriber than General Practitioner. Furthermore, prescriptions of both Specialized Practitioner and General Practitioner had many problems. In conclusion, It could be cut down the excessive medical expense and expected more efficient medical care by reducing DRPs, thus contributing to the improvement of national health. In order to pharmacist must have good professional ability of pharmacotherapy to help the physician for the drug selection.

노인들의 일반의약품 및 건강기능식품 복용실태 평가

김재윤(Jae Yoon Kim),이보름(Bo Reum Lee),장제관(Je Kwan Jang),조하나(Ha Na Cho),이지선(Ji Sun Lee),김미경(Mi Kyung Kim),이명구(Myung Koo Lee),임성실(Sung Cil Lim) 대한약학회 2009 약학회지 Vol.53 No.6

Aging society and aged society are determined by the component ratio of the elderly to the whole population; aging society is defined as a society whose ratio of the elderly population is less than 7%, and it is called aged society when the ratio is over 14%. Korea's aging process is so fast and unprecedented over the world according to many statistical data and investigations. The purpose of this study was to provide guidance and basic data to educate the elderly for the proper use of medication and health functional food. This study was carried out on 80 subjects of age 65 or older in Cheong Jusi in Choogncheongbuk-do. They answered questionnaire that was prepared for this study. The data were collected from August 4, 2008 to August 18, 2008. The collected data were analyzed by using the SPSS 12.0OK (for window) program and Microsoft EXCEL. The following is a summary of the results of this study. First, in the aspect of purchasing, the majority of respondents bought OTC drugs and health functional food for health and illness prevention. Purchasing places of drugs were diverse. Second, in the aspect of taking drugs, the older answerers were, the higher the number of drugs being taken was. Third, in the aspect of proper storage of drugs, most respondents have no specific spaces. Finally, regarding recognition of drug abuse and disposal, most people have little awareness or have no idea.

방사선 검사에 사용되는 조영제 Iopamidol의 안전성 평가

박창묵(Chang Mook Park),이명구(Myung Koo Lee),송태범(Tea Bum Song),이보름(Bo Reum Lee),임성실(Sung Cil Lim),장제관(Je Kwan Jang),이유정(Yu Jeung Lee) 대한약학회 2009 약학회지 Vol.53 No.6

Contrast media are substances that are used to enhance the contrast of structures or fluids within the body in medical imaging. Those are commonly used to enhance the visibility of blood vessels and the gastrointestinal tract. The aim of this study is to evaluate patients who got injected iopamidol, developed as one of contrast medium regarding changes in cardiovascular system and especially, adverse drug reactions. This study were performed on randomly selected a total of 51 patients (range of 15~85 years old) who got injected contrast medium, Iopamidol at a P hospital in Gyeonggi province from September 22nd, 2008 to January 24th, 2009. Data were collected by questionnaire though person to person. We analyzed the data by SPSS (Version 12. for windows). Methods of analysis were frequency and cross analysis. In results, 19.6% (n=10) were founded for adverse drug reactions of contrast medium. 25.0% (n=4) of 10 patients who had adverse drug reactions of contrast medium had took abdomen contrast test. 2 patients of those took contrast test for chest. Also, 3.9% (n=2) patients felt vomiting and nausea after injection of contrast medium. In conclusion, 19.6% patients experienced adverse drug reaction of contrast medium. Therefore, when taking radiation test, we should make efforts to minimize adverse drug reactions to achieve suitable and effective treatment.

치료의 증진을 위한 당뇨전문약사의 필요성

박인경(In Kyung Park),이수영(Soo Young Lee),윤지연(Jee Yeon Yun),한옥연(Ok Youn Han),이보름(Bo Reum Lee),장제관(Je Kwan Jang),나현오(Hyen Oh La),임성실(Sung Cil Lim) 대한약학회 2009 약학회지 Vol.53 No.4

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia and abnormalities in carbohydrate, fat, and protein metabolism which is resulting chronic microvascular, macrovascular, and neuropathic complications. Therefore, correct and consistent educations for pharmacotherapy is important and especially drug consultation by the specialty pharmacist of diabetic pharmacotherapy is necessary for all diabetic patients. The purpose of this study is to evaluate the necessity of the specialty pharmacist of diabetic pharmacotherapy and this study was performed from June 31th, 2008 to October 9th, 2008 in Kangnam St. Mary’s Hospital, Seoul, S. Korea throughout the questionnaire and evaluated the total 68 patients who were participating the multidisciplinary diabetes team programs. We evaluated the patient characteristics (n=68), learning status (difficulty 70.4%), wanted further education (68.3%) and preference of educator (pharmacist 46%) after finishing team teaching by multidisciplinary diabetes team program. In conclusion, many diabetic patients(80.3%) wanted individual and further drug consultation by the pharmacists who are specialized in the diabetes individually and they are needed.