종골의 초음파영상을 통한 소아성장에 관한 연구

장규태,김장현,서영민,Chang, Gyu-Tae,Kim, Jang-Hyun,Seo, Young-Min 대한한방소아과학회 2003 대한한방소아과학회지 Vol.17 No.2

Objectives: The purpose of this study was to suggest a scientific method for measurement of children's growth development. Ultrasonic image of calcaneus bone has some advantages that it is harmless to human body and apply a new imaging analysis algorithm. it can be used for the diagnosis of growth analyzed the opening degree of growth plate and bone density. Methods: This clinical study have been carried out with the 57 case(male 24, female 33) of the children aged 5 to 14 years old who visited in Department of Pediatrics, Dongguk university Bundang Oriental Hospital. Bone maturity is measured by the opening degree of growth plate and bone density in ultrasonic image of calcaneus bone This study were designed to investigate the relationship of the development of children and the calcaneus bone maturity. Result: The opening degree of growth plate was no change in aged 5-10 years for male and 5-9 years for female but decreased significantly from aged 11 years for male and 10 years for female. the bone density was no change in aged 5-12 years for male and 5-11 years for female but increased significantly from aged 13 years for male and 12 years for female. it was confirmed that bone maturity in female is more rapid than in male. The opening degree of growth plate of claclneus bone was correlated with age, height, weight. The bone density was correlated with age, height, weight, BMI in this suudy(P<0.001) Conclusion: The opening degree of growth plate and bone density of calcaneus bone are sufficient diagnostic worth as an index to predict adolescent growth.

소아 근시에 대한 임상 연구 고찰 - 최근 중의학 문헌을 중심으로 -

장규태,김장현,최은영,Chang, Gyu-Tae,Kim, Jang-Hyun,Choi, Eun-Young 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.1

Objective : The aim of this study was to investigate treatment of childhood myopia in current Traditional Chinese Medical Journals. Material and Method : We searched for treatment of childhood myopia in all Traditional Chinese Medical Journals published from January 2001 to October 2005. Results : Thirteen articles were selected and 7 of them showed total improvement rate was higher than 90% in childhood myopia. Treatment methods were acupuncture, auricular acupuncture, moxibustion, herbal medicine, adhesive plaster. Conclusion : Oriental medical treatments for childhood myopia were presumed to be effective in most trials. But there remains a debate about diagnosis and outcome criteria. Further studies are needed.

야뇨(夜尿)의 침구(鍼灸) 치료(治療) 연구(硏究) - 최근 중의 잡지를 증심으로 -

장규태,김장현,오주영,Chang, Gyu-Tae,Kim, Jang-Hyun,Oh, Ju-Young 대한한방소아과학회 2005 대한한방소아과학회지 Vol.19 No.1

Objectives : This study aimed to investigate acupuncture trend of childhood nocturnal enuresis in current Traditional Chinese Medical Journals. Methods : During the period from January 2000 to August 2004, we searched all Traditional Chinese Medical Journals in oriental medical library in dongguk university. We selected 28 literatures on acupuncture treatment for nocturnal enuresis in children Results : 28 studies are included and classified by diagnosis criteria and outcome criteria. And reclassified into two large groups, case report and comparison study. Totally 2324 cases, complete cures are 1701, significant improvements 2239, complete cure rate 73.2%, total improvement rate 97.3% 33 acupuncture points are used and main meridians are bladder, conception vessel and governor vessel. Conclusion : There remains a debate about diagnosis and outcome criteria. But Acupuncture is very effective and safe in the treatment of enuretic children.

황금(黃芩)이 니코틴 중독에 미치는 효과

장규태,김장현,서영민,Chang, Gyu-Tae,Kim, Jang-Hyun,Seo, Young-Min 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.1

Objective : The purpose of this study is to investigate the effect of Radix Scutellariae on repeated nicotine-induced locomotor activity and c-Fos expression utilizing Fos-like immuno-histochemistry method in the nucleus accumbens, and the striatum, one of the major projection areas of the control DA system. Methods : Male Sprague-Dawley rats were divided into untreated(normal), nicotine-treated (control), Radix Scutellariae-treated(sample) groups, RS group received Radix Scutellariae(100mg/kg, i.p.) 30minutes before injection of nicotine(0.4mg/kg, s.c.) for 7days. Rat were followed withdrawal for 3 days and one challenge for 1day. Results : Systemic challenge with nicotine produced a much larger locomotor activity and expression of c-Fos in the nucleus accumbens and the striatum. Pretreatment with Radix Scutellariae decreased in nicotine-induced locomotor activity and c-Fos expression in the core, shell, straitum area. Conclusion : These results demonstrated that reduction in locomotor activity by Radix Scutellariae may be mediated by reduction of dopamine release and of postsynaptic neuronal activity in striatum, the nucleus accumbens. Out results show neurochemical evidence for the biological effects of Radix Scutellariae that ultimately may help us to understand how Radix Scutellariae can be used to treat nicotine addiction.

야뇨의 병력청취 연구

장규태,김장현,오주영,Chang, Gyu-Tae,Kim, Jang-Hyun,Oh, Ju-Young 대한한방소아과학회 2004 대한한방소아과학회지 Vol.18 No.2

Objectives : In evaluating a child with enuresis, an organized approach to the history leads to a working diagnosis and an appropriate treatment plan. but, there's no study about history taking in enuretic children. This article was undertaken to evaluate the enuretic child exactly and to study nocturnal enuresis systematically. Methods : It was conducted a computerized literature search in following database: Medline (via Pubmed), NDSL, EBSCO. Korean articles via oriental pediatric association homepage, KISS. Key words to search were 'nocturnal enuresis', 'bedwetting', 'enuresis', 'incontinence', 'management', 'evaluation', 'assessment', 'questionnaire', 'guideline', 'voiding dysfunction'. Results : Questions are grouped in eight categories: primary history(sex, age, height, weight), family history, enuresis history(primary/secondary, frequency, time of enuresis, nocturia), voiding history(average number, frequency, pattern, volume, posture, daytime enuresis), medical history, constipation/encopresis, sleep(OSA). Conclusion : A careful, complete history taking will help to plan treatment properly and to study.

식욕부진(食慾不振)을 나타내는 소아(小兒)의 한의학적(韓醫學的) 치료(治療)에 관한 최근(最近) 경향(傾向)

장규태,Chang, Gyu-Tae 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.1

Anorexia is one of the most common childhood-onset symptom and is Icing-term progress. Public interest in anorexia has increased along with debate concerning painless treatment. This study was progressed for oriental medical treatment for anorexia in china. The purpose of this study is current oriental medical approach to anorexia. Anorexia was named 'yanshizheng(厭食症)' in chinese medicine. The study for anorexia in china consist of basic, clinical, experimental study. In the oriental medicine, the reason of anorexia is weekness of the spleen and the stomach(脾胃虛弱), indigestion for milk and food(乳食停滯). The method of treatment is strengthening the spleen and pacification the stomach(健脾和胃). It should help primary care providers in their assessment of common child health problem.

주의력결핍과잉행동장애의 진단 및 평가 - 행동평정척도들을 중심으로 -

장규태,한윤정,Chang, Gyu-Tae,Han, Yun-Jeong 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.2

Objective : This study is to investigate the method for assesment and diagnosis of ADHD, especially focusing on behavior rating scales. Methods : We searched the recent date of the publication and paper in ADHD. Results : For Assesment and Diagnosis of ADHD, various method such as interview with parents, child and teacher, behavior observation, behavior rating scales and neuropsychological test are used. The structured interview consists of the restrictive questions and response, and then have diagnostic algorithm, consequently can be used by untrained clinicians. Of the structured interview, standardization of K-SADS in Korean version is finished. Behavior rating scales, the form of parent, teacher and self-report questionnaires, are used as diagnosis and treatment evaluation of ADHD. Behavior rating scales consist of both ADHD-specific scales and broad-band scales designed to screen for various symptoms (including ADHD symptoms). ADHD-specific scales are useful in differential diagnosis, discrimination of subtype, treatment evaluation, However, broad-band scales are useful in preliminary examination. The neuropsychological tests can evaluate attention deficit and effect of attention deficit on cognitive function and academic performance. The neuropsychological tests also used in diagnosis and treatment evaluation of ADHD. Conclusion : For Assesment and Diagnosis of ADHD, various method are used, especially behavior rating scales are both useful and simple tool for diagnosis and treatment evaluation.

가감시평탕(加減柴平湯) 효능(效能)에 대한 임상적(臨床的) 연구(硏究) - 소아(小兒)의 발열(發熱)에 대한 효과(效果)를 위주(爲主)로 -

장규태,김장현,Chang Gyu-Tae,Kim Jang-Hyun 대한한방소아과학회 1998 대한한방소아과학회지 Vol.12 No.1

The purpose of this study was on effect of Gagamsipungtang(GGSP) which removal of fever, side effect etc. During 4months between September and December 1998 , GGSP water extract administered to the patients coming to Dept. of Pediatrics, Dongguk university Pundang Oriental Hospital on account of the symptom of fever with common cold in acute stage, and this study was conducted for 97 children (male 55, female 42). GGSP was used in children both men and women. There were 13 kinds of complications including cough, nasal obstruction, headache, nausea, anorexia, chilling and sweat etc. The distributions of remedial value were improved(62.9%) and no improved(37.6%) patients. 'Improved' standed for no fever over 2 days after GGSP used to patients. GGSP was affected in remedial values by only used without antipyretics. Side effect were diarrhea, anorexia, vomiting and so on.

강활(羌活)이 가토(家兎) 혈관평골근(家兎 血管平滑筋)의 긴장성(緊張性) 조절(調節)에 미치는 영향(影響)

장규태,김장현,Chang Gyu-Tae,Kim Jang-Hyun 대한한방소아과학회 1998 대한한방소아과학회지 Vol.12 No.1

The purpose of this study was to analyze the Rhizoma on the blood pressure, heart rate and to define the mechanism of Notopterygii Rhizoma-induced relaxation in rabbit common carotid arterial contracted by agonists. Method : In order to explore the effect of Notopterygii Rhizoma on the blood pressure and heart rate, Notopterygii Rhizoma extract was injected in vein of rabbit ear. In order to investigate the effect of Notopterygii Rhizoma on norepinephrine(NE)-induced contracted rabbit carotid arterial strips, transverse strips with intact or damaged endothelium were used for the experiment using organ bath. To analyze the mechanism of Notopterygii Rhizoma-induced relaxation, Notopterygii Rhizoma extract infused into NE-induced contracted strips induced by agonists after treatment of methylene blue, propranolol, ouabain and it infused into serotonin, potassium chloride-induced contracted strips. Result : The blood pressure was significantly decreased by Notopterygii Rhizoma, but heart rate was insignificantly. In addition, Notopterygii Rhizoma significantly relaxed the norepinephrine, serotonin, potassium-induced contracted strips with intact endothelium or damaged endothelium. The relaxing effect of Notopterygii Rhizoma In NE-induced contracted strips with damaged endothelium by pretreatment of methylene blue, propranolol was not changed, but Ouabain was significantly decreased. Conclusion : These results were shown that Notopterygii Rhizoma affected the NE -induced contracted smooth muscle without the participation of endothelium, and demonstrated that the mechanism of NotoDtervgii Rhizoma-induced relaxation was the obstruction of receptor-operated Ca2+ channel.

소아의 골밀도에 관한 연구

장규태,김장현,서영민,Chang, Gyu-Tae,Kim, Jang-Hyun,Seo, Young-Min 대한한방소아과학회 2005 대한한방소아과학회지 Vol.19 No.1

Objectives : Osteoporosis is generally occurred in old age, especially postmenopausal women therefore, it is relatively overlook osteoporosis in children, but the authors have paid attention to bone density in children because maximizing peak bone mass of childhood is advocated as a way to prevent osteoporosis and environmental factor of childhood play role in the regulation of bone density. the present study was performed to measure bone density of children and to assess the influence of age, sex, body size, exercise, weak symptoms on bone density during the period of bone growth. Methods : We have measured bone density of calcaneus bone in 283 children (male 144 female 139, ranged from3 to 18) who visited in growth clinic of Pediatrics, Dongguk University Bundang Oriental Hospital, using quantitative ultra sound densitometry and they were divided into 3 groups by age(3-10, 11-15, 15-18 years). Pearson's correlation was used to assessed the influence of age, body size and Student's t-test was used to detect differences in sex, exercise, weak symptoms between the groups on bone density Results : The bone density correlated with age, height, weight, body mass index in this study. Bone density were significantly higher in males than in female. Digestive weak children's bone density were lower than normal children. Conclusion : Weight-bearing exercise and food rich in nutrition are necessary to increase maximizing peak bone mass in children.