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자궁경부종양에 있어서 증상군과 무증상 검진군간의 병기 비교
임현우,이원철,황인영,권용일,박종섭,김훈교,Yim, Hyeon-Woo,Lee, Won-Chul,Hwang, In-Young,Kwon, Yong-Il,Park, Jong-Sup,Kim, Hoon-Kyo 대한예방의학회 1998 예방의학회지 Vol.31 No.4
Screening is for the early detection and treatment of diseases in prior to development of symptoms, so that more favourable prognosis could be obtained. To evaluate efficiency of screening test for cervical neoplasms, we compared the histopathologic stages of asymptomatic cervical neoplasm patients diagnosed by screening test, with those of symptomatic patients confirmed by pathology. Total 1,120 cases of cervical neoplasm patient, diagnosed at Kang-nam St. Mary's hospital from Jan. 1990 to Dec. 1996, were reviewed by chart, and classified as asymptomatic and symptomatic group based on the presence of subjective symptoms on their hospital visit. Their histopathologic stages were analysed. The results were as follows, 1. From the total of 1,120 patient, asymptomatic group comprised 264 cases (25.5%). Asymptomatic proportion increased 15.3% in 1991 to 34.7% in 1996. 2. Mean age for the occurrence of cervical neoplasm was $44.3{\pm}10.4$ years for the asymptomatic group, and $49.3{\pm}13.2$ years for the symptomatic group, showing statistically significant differences (p=0.001). 3. Among the study subjects, 465 cases(45.0%) had preinvasive lesions and 569 cases(55.0%) had invasive cancers. 4. Percentage of cervical neoplasm patient diagnosed at asymptomatic stages were 45.8% in twenties, 32.0% in thirties, 27.7% in forties, 21.7% in fifties, 18.7% in sixties and 1.8% in above seventies, showing statistically significant differences according to age group(p=0.001). 5. In thirties, 87.2% of the asymptomatic patients were diagnosed as preinvasive lesion and 45.0% of symptomatic patient were diagnosed as preinvasive lesion. With increment of ages, preinvasive lesion proportion were markedly decreased. 6. 76.9% of asymptomatic patients were diagnosed as preinvasive lesion, and 34.0% of symptomatic patients were diagnosed as preinvasive lesion, suggesting screening test at asymptomatic stage can increase preinvasive lesion proportion. 7. preinvasive lesion proportion of asymptomatic patient was highest in thirties(40.4%) and 2nd highest in forties(34.0%). Screening test for cervical neoplasm should be actively carried out from the thirties.
박영준,임현우,박용문,이원철,Park, Young-Jun,Yim, Hyeon-Woo,Park, Young-Moon,Lee, Won-Chul 대한예방의학회 2007 예방의학회지 Vol.40 No.6
Objectives : Obesity is currently an epidemic in Korea, and sleep duration is thought to be one of the risk factors for obesity. The objective of this study was to test the hypothesis that short sleep duration is associated with obesity in Korean adults. Methods : The data from the 2001 Korean National Health and Nutrition Survey were used, and 6,174 subjects aged $18{\sim}80$ years were included in the analysis. Sleep duration was measured using information obtained from self-reported questionnaires. Obesity, the main outcome variable, was measured according to body mass index. Multiple regression modeling was used to adjust for potential confounding variables. Results : The study results revealed a negative association between sleep duration and body mass index among Korean adults. These associations persisted after controlling for the potential confounding variables. Conclusions : These findings support the hypothesis that sleep duration is associated with obesity in Korean adults. In addition, these observations support earlier experimental sleep studies and provide a basis for future studies on weight control intervention by increasing the amount of sleep.
하희승(Hee Sung Ha),임현우(Hyeon Woo Yim),박용문(Yong-Moon Park),이진희(Jin-Hee Lee),이승환(Seung-Hwan Lee),권혁상(Hyuk Sang Kwon),윤건호(Kun-Ho Yoon),손호영(Ho-Young Son),강무일(Moo-Il Kang),이원철(Won Chul Lee) 한국역학회 2008 Epidemiology and Health Vol.30 No.2
Purpose: Prevalence of metabolic syndrome is increasing markedly in rural area of Korea. Alcohol drinking and smoking are the main risk factors which shows the highest prevalence rate among the risk factors of metabolic syndrome. The aim of this study was to investigate the association between metabolic syndrome and alcohol drinking and smoking histories in a rural area of Korea. Methods: Data was obtained from 1,332(507 men, 825 women) individuals aged over 40 years who lived in rural area of Chungju city in 2007. Metabolic syndrome was defined by NCEP ATP criteria and waist circumference was defined by WHO-APR(Asia Pacific Region). Data analysis was carried out using SAS version 8.02. Results: In men, adjusted odds ratio for metabolic syndrome was 2.78(1.09-7.05) for current alcohol drinker, 2.75(1.38-5.51) for past alcohol drinker, 3.25(1.58-6.67) for under 21 years old at start of alcohol drinking, 2.62(1.12-6.11) for light alcohol drinker, 6.01(2.65-13.64) for heavy alcohol drinker. In women, all the alcohol related risk factors were not statistically significant with metabolic syndrome. For all the smoking related risk factors were not statistically significant with metabolic syndrome in men and women. Adjusted odds ratio of alcohol drinking habits for each components of diagnostic criteria of metabolic syndrome was significant for high blood pressure, high fasting glucose and hypertriglyceridemia in men and abdominal obesity in women. Adjusted odds ratio of cigarette smoking habits for each components of diagnostic criteria of metabolic syndrome was significant for abdominal obesity in women. Conclusion: Controlling alcohol drinking habits in men should be reinforced in order to prevent the metabolic syndrome in a rural area of Korea.
윤상헌(Sang-Heon Yoon),임현우(Hyeon Woo Yim),이원철(Won-Chul Lee) 한국역학회 2008 Epidemiology and Health Vol.30 No.1
Cancer screening evaluation will be a important issue in Korea in near future, Bias in cancer screening evaluation is well known by concept, but it is not applied yet using the data from screening program of Korea. So introducing the way how the bias is adjusted will be helpful. This review deals with the type, meaning, the way how the bias is adjusted, and examples. Especially, lead-time bias, length bias and self-selection bias were focused. Adjusting bias is one of the imperative step for epidemiologic analysis. Understanding the background concept and experience using the screening program data will be helpful for estimating the effectiveness of national screening program of Korea.
정승희(Seunghee Jeong),임현우(Hyeon Woo Yim),정영은(Youngeun Jung),조선진(Sunjin Jo),전태연(Taeyoun Jun),정성원(SungWon Jung),이민수(Minsoo Lee),김재민(Jaemin Kim) 한국역학회 2008 Epidemiology and Health Vol.30 No.2
Purpose: People with a family history of mood disorder are more likely to have depression. This study compared the characteristics of non-psychotic major depression disorder according to family history of depression. Method: Subjects were total of 817 persons recruited for the CRESCEND-K multicenter trial. Characteristics of depression and suicide history of patients with and without a family history of depression were assessed. Family history was determined through self-report. Results: Of 817 participants, 12.4% had a positive family history of depression. Those with family history of depression reported an earlier age at onset of MDD, and more psychiatric comorbidity. Severity of depression and anxiety were not different according to family history of depression. There were no difference in attempted suicide history, number of attempted suicide and age at onset of 1st attempted suicide according to such a family history. Conclusion: Patients with family history of depression reported earlier onset of MDD and more history of psychiatric comorbidity.
조현주(Hyun-Ju Cho),임현우(Hyeon-Woo Yim),현명호(Myoung-Ho Hyun),조선진(Sun-Jin Jo),지유나(Yu-Na Ji),전태연(Tae-Youn Jun),방명희(Myeung-Hee Bang) 대한스트레스학회 2008 스트레스硏究 Vol.16 No.3
본 연구는 지역사회 일반인들의 우울증 태도 질문지를 개발하기 위해 구성 개념을 확인하고자 시행하였다. 연구대상은 Y 지역주민 중 층화군집 무작위 추출하여 연구에 동의한 성인 26명이다. 연구진이 참여자를 심층 면담한 축어록을 푼 뒤, 개방 코딩(open coding)을 이용하여 질적인 분석을 실시하였다. 연구결과, 상위 개념으로 우울증 지식과 우울증 태도가 추출되어 두 개념을 분리할 필요성이 제기되었다. 우울증 지식은 우울증 원인, 증상, 치료에 관한 3요인으로 구성되었다. 일반인은 우울증의 증상은 잘 이해하고 있으나 원인은 심리적으로, 치료는 개인의지나 스쳐 지나가는 병으로 인식하는 범주가 많이 나타났다. 우울증 태도는 정서적 거리, 낙인, 가족주의, 개인결함 네 가지 요인으로 구성된다. 일반인은 우울증 환자에 대해 부정적인 정서를 갖고, 편견을 보였으며 환자가 가족인 경우에는 책임감을 느끼는 것으로 나타났다. 본 연구는 일반인의 우울증 태도에 대해 심층 면담한 뒤 그 자료를 질적 분석하여 우울증 태도에 관한 구성 개념을 확인한데 의의가 있다. 본 연구를 통하여, 향후 우울증 예방을 위한 심리교육적 개입에 대한 효과를 검증하는 도구로 발전되고 활용될 수 있으리라 기대한다. This study examined the concepts of depression in oder to develop the depression attitude questionnaire in adult. The participants of study were 26 adults who agreed with our study among the stratified clustered random sampling. Based on ground theory, the data from transcribed interviews were analyzed by using open coding. The result of this study presented the concepts of depression which composed of the knowledge of depression and the attitude of depression. Finally, we were separate the concepts of depression into two questionnaires. The questionnaire for knowledges of depression was composed of the cause, symptoms, and treatment of depression. Most of participants were understood the symptoms of depression well but considered the cause of it to psychological factor, and depression are not genuine disease. The attitudes toward depression were compose of emotional distance, stigma, familism, personal weakness. Participants have a negative emotion to depressive patients and have stigma to them, but they have responsibility to their family member who have depression. We expect that result of the study will be a base upon the development of psychometric tool for depression attitude.
우울증 자살시도자들에서 표준우울평가척도들의 요인분석 : CRESCEND 연구
홍민아,김민경,김정범,전태연,임현우,이민수,김재민,Hong, Min Ah,Kim, Min Kyung,Kim, Jung Bum,Jun, Tae Youn,Yim, Hyeon Woo,Lee, Min Soo,Kim, Jae Min 대한불안의학회 2015 대한불안의학회지 Vol.11 No.1
Objective : The aim of this study was to find associations between specific symptoms and suicidal behavior by using global severity on depression scales. Methods : Data were obtained from 1,183 patients of CRESCEND study. Factor analysis of the 17-item Hamilton Rating Scale for Depression (HAM-D) and the Beck Depression Inventory-II (BDI-II) was used to compare symptom clusters between the past suicide attempters and the non-suicide attempters, among the patients with depressive disorders. Results : Factor analyses of HAM-D and BDI-II extracted three factors. Suicide attempters had significantly higher scores on core factor of HAM-D, including depressed mood, feeling of guilt, suicide, work, and activities. The higher scores on all factors of BDI-II or scores correlated with a total of 7 suicide attempts and with known risk factors for suicidal behavior. Conclusion : These findings suggest that the suicide attempters complained of more cognitive, affective, somatic symptoms on BDI-II, but the core factor on HAM-D was the only differentiated factor between the two groups. Clinician-rated scales as well as self-reported questionnaires were valid in measuring suicidal attempts, and the clinical profile may help in guiding the studies of biological correlates and the treatments to reduce suicide risk.