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이승훈,정원혁,최홍식,김수찬,임재중,김덕원,Lee, Seung Hoon,Jung, Won Hyuk,Choi, Hong-Shik,Kim, Soo-Chan,Im, Jae-Joong,Kim, Deok-Won 한국음성학회 2005 음성과학 Vol.12 No.4
Voice is made by systemic interaction of respiration, vocalization, articulation and resonation. There is no existing multi-channel voice analysis system to assess voice and respiration simultaneously. The most existing systems consist of. vocal fold vibration measurement such as stroboscopy, EGG (electroglottography) or laryngeal electromyography and voice analysis system. Since respiration has close relationship with voice simultaneous analysis of both vocal cord vibration and respiration are essential. In this study, a four channel integrated system are developed for acoustic analysis through microphone, vocal fold vibratory analysis using EGG, and respiratory analysis using two channel RIP (respiratory inductive plethysmography).
서영준,정성우,강학수,임재중,허영성,우순섭,심광섭,황경균,Seo, Young-Jun,Jung, Sung-Woo,Kang, Hag-Soo,Im, Jae-Jung,Huh, Young-Sung,Woo, Soon-Seop,Shim, Kwang-Sup,Hwang, Kyung-Gyun 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.4
In esthetic treatment of bimaxillary protrusion, it is important to move backward the anterior teeth segment. For the backward movement of the anterior teeth segment, orthodontic force and segmental osteotomy have been applied on the clinical treatment until recently. These methods caused long treatment time, anchorage loss, the possibility of root resorption and the complication followed by segmental osteotomy. Therefore, corticotomy has become a major concern lately. This research has been conducted to study the efficiency of corticotomy in the treatment of bimaxillary protrusion comparing the profile change, canine retraction velocity and space closing time. The research compared and analyzed space closing time, canine retraction velocity and profile change in two groups of patients. Both groups were formed out of patients over 18 years old who visited the department of dentistry in Hanyang University for treatments. The experimental group who was treated by corticotomy and Skeletal Anchorage System(SAS). The control group who received orthodontic treatment using SAS. The following results are produced after analyzing both groups. The significant statistic difference in space closing time has been observed in the experimental group as compared with the control group(p<0.05). In the experimental group, the significant statistic increase in canine retraction velocity was also observed(p<0.05). There was no significant difference in profile change between the control group and the experimental group(p<0.05). As a result, orthodontic treatment using corticotomy has a reasonable efficiency in space closing time as compared with the existing orthodontic treatment. Therefore, it is concluded that corticotomy with orthodontic treatment can be reasonably applied to dentofacial abnormality.
치과치료를 위한 정주진정법에 사용되는 미다졸람에 대한 역설적 반응 -증례 보고 및 문헌고찰-
전재윤,정세화,이병하,임재중,황경균,심광섭,박창주,Jeon, Jae-Yun,Jung, Se-Hwa,Lee, Byung-Ha,Im, Jae-Jung,Hwang, Kyung-Gyun,Shim, Kwang-Sup,Park, Chang-Joo 대한치과마취과학회 2009 Journal of Dental Anesthesia and Pain Medicine Vol.9 No.2
Midazolam, one of the most common benzodiazepine derivatives, is widely used in intravenous sedation for dental treatment without severe complications. However, paradoxical reactions to midazolam, including patient's unanticipated restlessness, agitation, hostility, and rage, have been frequently reported since the introduction of benzodiazepine. During outpatient intravenous sedation using midazolam for dental treatment, we experienced a paradoxical reaction to midazolam in a 28-year-old female patient. With a thorough review of the literature, the management of this complication and its various etiologies were discussed.
치과 치료를 위한 외래 정주진정 법에 대한 다기관 후향적 임상연구
정세화,백상현,노현기,강나라,임재중,이병하,전재윤,황경균,심광섭,박창주,Jung, Se-Hwa,Baik, Sang-Hyun,Roh, Hyun-Ki,Kang, Na-Ra,Im, Jae-Jung,Lee, Byung-Ha,Jeon, Jae-Yoon,Hwang, Kyung-Gyun,Shim, Kwang-Sup,Park, Chang-Joo 대한악안면성형재건외과학회 2009 Maxillofacial Plastic Reconstructive Surgery Vol.31 No.5
Purpose : On outpatient facilities, our sedation protocol focuses on the intermittent bolus injections of midazolam intravenously, according to patient's and operator's needs during the dental treatment. This multicenter retrospective study was aimed to prove the efficiency and safety of our sedation protocol. Patients and Methods : In three centers using the same outpatient sedation protocol for dental treatment (Division of Oral and Maxillofacial Surgery/Department of Dentistry in Hanyang University Medical Center, S-plant Dental Hospital. and Grand Oral and Maxillofacial Surgery), total 937 patients had various dental treatments under intravenous conscious sedations with independent patient monitoring from March 2006 to March 2009. By reviewing charts, we analyzed the results of sedation and dental treatment, retrospectively. Results : Our sedation protocol had no severe postoperative complications requiring admission. while showing good compatibility with almost all dental treatments, with acceptable satisfaction of both patients and operators. Conclusion : We assure that our sedation protocol can be used efficiently and safely on routine outpatient basis. We also hope that this study will provide the concrete concepts to common dental practitioners, who desire to perform sedation for dental treatment.
정상 치은 조직에서 배양된 각화세포에서 Cyclosporine A에 의한 MMP-1, TIMP-1, TGF-β1의 발현에 관한 연구
강학수(Hag-Soo Kang),이재선(Jae-Sun Lee),빙정호(Jung-Ho Bing),박창주(Chang-Joo Park),임재중(Jae-Jung Im),황경균(Kyung-Gyun Hwang),심광섭(Kwang-Sup Shim) 대한구강악안면외과학회 2008 대한구강악안면외과학회지 Vol.34 No.4
Purpose : Cyclosporine A (CsA) is a versatile immunosuppresive agent used to prevent graft rejection syndrome and treat autoimmune disease. One of the major side effects associated with CsA is the abnormal gingival hyperplasia. The purpose of this study was to investigate the relationship between the mRNA expression of the MMP-1, TIMP-1, and TGF-β1 and the concentration of CsA in cultured human gingival keratinocytes. Materials & Methods : Gingival keratocytes were obtained from gingival tissues of 4 healthy donors. The cultured gingival keratocytes were incubated with increasing concentrations of CsA (0-2000 ng/ml) for 24 hours and the expression of MMP-1, TIMP-1, and TGF-β1 were determined by reverse transcription-polymerase chain reaction (RT-PCR). Results : The expressions of MMP-1 and TGF-β1 were not significantly different according to the concentrations of CsA. The expression of TIMP-1 was significantly increased at the CsA concentration of 500 ng/ml. Conclusion : We concluded that the gingival hyperplasia induced by CsA was more related with TIMP-1 than MMP-1 or TGF-β1 on gingival collagen metabolism in patients treated with CsA.
Diazepam 투여시 진정정도에 따른 Long Latency Auditory Evoked Potentials 의 P300의 변화
김영재,박진우,김정환,박주열,신치만,최영균,정순호,권대성,임재중 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.2
Background : P300 component of the long latency auditory evoked potentials(LLAEPs) provides information on conscious and cortical funtion. The P300 wave occures only for stimuli that somehow capture the patients attention. Therefore LLAEPs implys a degree of cognitive processing. We studied sedation scale and P300 wave to determine if LLAEPs could be utilized as electrophysiologic predictors of sedation. Methods : The P300 component of LLAEPs from vertex was recorded from 10 ASA physical status I and II patients undergoing elective surgery while they listened via headphones to a series of clicks which were interrupted unpredictably by a tone burst(2 KHz) before and after diazepam 0.04 mg/kg and 0.08 mg/kg IV. The patients were asked to concentrate on the clicks and to press a button whenever they detected a 2 KHz tone. And sedation scale also was measured. Results : Amplitude of P300 was decreased and latency of P300 was increased in a dose-dependent manner with IV diazepam. Amplitude was greatest and latency was shortest in awake. And sedation scale also was increased according to increased IV diazepam adminstration. Conclusions : Both amplitude and latency may be highly related to the sedation scale with progressively increasing dose of diazepam. Therefore we conclude that P300 component of LLAEPs can be utilized as an electrophysiologic predictor of awareness and sedation. (Korean J Anesthesiol 1997; 33: 248∼253)