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산화적 손상에 의해 유발된 심근세포 독성에 대한 보양환오탕(補陽還五湯)의 방어효과
임은경,정현애,신선호,이윤재,Rhim, Eun-Kyung,Jeong, Hyun-Ae,Shin, Sun-Ho,Lee, Yun-Jae 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.2
The water extract of Boyanghwanoh-tang has been used for treatment of ischemic vascular disease in oriental medicine. However, little is known about the mechanism by which the water extract of Boyanghwanoh-tang rescues cells from these damages. Therefore, this study was designed to evaluate the protective effects of Boyanghwanoh-tang on zinc-mediated cytotoxicity in H9c2 cardiomyoblast cells. This study demonstrates that, after treatment of H9c2 cells with zinc, there was a decrease in cell viability in a dose dependent manner, and there was a chromatin condensation. Zinc induced the change of cell morphology. In addition, zinc induced mitochondrial dysfunction. Zinc-induced H9c2 cell death was remarkably prevented by the pretreatment of Boyanghwanoh-tang consistently with increase of the peroxoredoxin 1, 2, 3, 5, and 6 expression. Taken together, the results suggest that zinc induced severe cell death in H9c2 cardiomyoblast cells, and that protective effects of Boyanghwanoh-tang against oxidative injuries are achieved through regulation of peroxiredoin expression.
Ramsay Hunt Syndrome 환자를 대황치자황백병(大黃梔子黃栢餠)과 용담사간탕가미(龍膽瀉肝湯加味)로 치료한 치험1례
임은경,이윤재,황상일,백동기,홍석훈,김송백,윤종민,양경석,최덕화,신선호,Rhim Eun-Kyung,Lee Yun-Jae,Hwang Sang-Il,Baek Dong-Gi,Hong Seok-Hoon,Kim Song-Baeg,Yun Jong-Min,Yang Kyung-Suk,Choi Deok-Hwa,Shin Sun-Ho 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.4
Ramsay Hunt Syndrome is caused by infection of herpes zoster and associated with otalgia, herpetic eruptions, facial palsy, trigerminal pain and cochleovestibular dysfunction such as deafness, tinnitus, vertigo and so on. A 60-year old female, who has tinnitus, peripheral facial palsy, deafness, vertigo, postauricular pain and herpetic eschar, had been admitted to Wonkwang University Oriental Jeonju Medicine Hospital. We treated this patient with Daehwangchijahwangbaeg-byung and Yongdamsagantang-gami, and the patients showed improvement in the symptoms. So we describe the process and contents about the way the patient was cured.
백동기,임은경,이윤재,정현애,조영기,문미현,이성균,김동웅,신선호,황상일,Baek, Dong-Gi,Rhim, Eun-Kyung,Lee, Yun-Jae,Jeong, Hyun-Ae,Cho, Young-Kee,Moon, Mi-Hyun,Lee, Seong-Kyun,Kim, Dong-Woung,Shin, Sun-Ho,Hwang, Sang-Il 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3
Multiple Sclerosis(MS) is an acquired, demyelinating disease of the central nervous system. Clinically, it is characterized by episodes of focal disorder of the optic nerves, spinal cord, and brain, which remit to varying extent and recur over a period of many years. The average age at diagnosis is 30, typically starting between the ages of 15 and 50. Women are affected at least twice as often as men. It is more common in persons of northern European heritage and those living furthest from the equator. The diagnosis of MS is based on a history of multiple attacks of neurologic lesions over time that affect different parts of the central nervous system. A case of MS was confronted. The patient was treated with Cheongsimyonjaum-gami(淸心蓮字飮加味), YangMyung channel(陽明) and had significant improvement was seen.
척추기저동맥부전환자를 천마구등음(天麻鉤藤飮)으로 치료한 치험 1례
송철민,장통영,임은경,이윤재,이정섭,신선호,이인,문병순,정현애,Song, Cheol-Min,Chang, Tong-Young,Rhim, Eun-Kyung,Lee, Yun-Jae,Lee, Jung-Sub,Shin, Sun-Ho,Lee, In,Moon, Byung-Soon,Jeong, Hyun-Ae 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3
Vertebrobasilar insuffciency(VBI) is also refered to as vertebrobasilar transient ischemic attack(V-B TIA). Vertebrobasilar insufficiency is often undiagnosed or misdiagnosed due to complexity of the symptoms. Transcranial doppler(TCD) can be used to possible to record the blood flow velocities in the cerebral arteries through the intact cranium. Transcranial doppler and magnetic resonance angiography(MRA) are both noninvasive techniques that can be used in vertebrobasilar insufficiency, but transcranial doppler is more sensitive with respect to evaluating stenotic lesion of the arteries than magnetic resonance angiographv. Diagnostic values of transcranial doppler were assessed in patients with vertebrobasilar insufficiency. A case of vertebrobasilar insufficiency is here reported. A 62-year-old man with dizzness, nausea and tremor because of vertebrobasilar insufficiency was admitted at Wonkwang Oriental Medicine Hospital. He was treated with the herbal medicine Chunmagudung-um and with acupunture. Results showed improvement of symptoms and favorable transcranial doppler readings. The process used in this successful treatment is here described.
당뇨합병증으로 인한 만성 신부전 환자 1례에 대한 임상적 고찰
문미현,조영기,임은경,황상일,백동기,송철민,장통영,정현애,윤종민,우인,신선호,이윤재,Moon, Mi-Hyun,Cho, Young-Kee,Rhim, Eun-Kyung,Hwang, Sang-Il,Baek, Dong-Gi,Song, Chul-Min,Jang, Tong-Young,Jeong, Hyun-Ae,Yun, Jong-Min,Woo, In,Shin, Sun- 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4
This study was designed to evaluate the effects of oriental medicine and acupuncture therapy on a chronic renal failure patient suffering complications from diabetes mellitus. Methods: The clinical data was analyzed on a patient with chronic renal failure complicated by diabetes mellitus whose main symptoms were edema and numbness of lower limbs, anorexia, indigestion, nausea, vomiting, and general weakness. The patient was admitted to the internal medicine department of Wonkwang University Oriental Jeonju Medicine Hospital on July 31, 2004, and remained until August 17, 2004. He was treated with herbal medicine(Palmijiwhangtanggamibang) and acupuncture therapy. Results: After treatment, improvement was seen in symptoms and laboratory examinations(creatinine clearance). Conclusions: This study suggests that oriental medicine therapy is significantly effective in the treatment of a chronic renal failure complicated by diabetes mellitus.
황련해독탕약침(黃連解毒湯藥針)을 이용한 흉부상열감(胸部上熱感) 치험(治驗) 2례(例)
김종욱,이윤재,임은경,신선호,김동웅,홍석훈,주종천,조권일,Kim, Jong-Uk,Lee, Yun-Jae,Rhim, Eun-Kyung,Shin, Sun-Ho,Kim, Dong-Woung,Hong, Seok-Hoon,Joo, Jong-Cheon,Cho, Gwon-Il 대한약침학회 2003 Journal of pharmacopuncture Vol.6 No.2
The purpose of this study is to evaluate the clinical effect of Hwangryunhaedok-tang Herbal-Acupuncture. Hwangryunhaedok-tang is used in all heating diseases. Chest Heating Sensation is a unique concept in Oriental Medicine. So we applied Hwangryunhaedok-tang Herbal-Acupuncture to treat the Chest Heating Sensation. We used DITI(Digital Infrared Thermographic Imaging) to estimate the temperatures of chest surface for the outcome assessment. We came to know that the chest surface temperatures were all reduced in both cases after Herbal-Acupuncture treatment. The reduced average temperature was $1.5^{\circ}C$ in case 1 and $0.9^{\circ}C$ in case 2. The above result indicates that Hwungryunhaedok-tang Herbal-Acupuncture treatment has an effect on Chest Heating Sensation, thus continuous Hwangryunhaedok-tang Herbal-Acupuncture study will be needed for more clinical applications.
Caroli's Disease로 인한 담관염 환자 치험 1례
문미현,이성균,정현애,이정섭,임은경,이윤재,문구,신선호,김동웅,조영기,Moon, Mi-Hyun,Lee, Seong-Kyun,Jeong, Hyun-Ae,Lee, Jung-Sub,Rhim, Eun-Kyung,Lee, Yun-Jae,Moon, Goo,Shin, Sun-Ho,Kim, Dong-Woung,Cho, Young-Kee 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.4
Caroli's disease is a non-obstructive dilatation of the intrahepatic bile ducts. It is a rare congenital disorder that classically causes saccular ductal dilatation, which usually it segmental dilatation. Caroli's disease is associated with recurrent bacterial cholangitis and stone formation. A 57 years-old female inpatient suffering from cholangitis due to Caroli's disease was admitted at Wonkwang University Jeonju Oriental Medicine Hospital. The patient was treated with herbal medicine such as Yongdamsagan-tang and acupuncture. As result, there was improvement of symptoms. The process and content of treatment and the patient's recovery over general symptoms is described.
뇌졸중 이후 불명열(Fever of Unknown Origin)로 진단 받은 환자를 청리자감탕가미(淸離滋坎湯加味)로 치료한 치험 1예
백동기,조권일,최진영,신학수,최우정,임은경,이윤재,김동웅,신선호,황상일,Baek Dong-Gi,Cho Gwon-Il,Choi Jin-Young,Shin Hak-Soo,Choi Woo-Jung,Rhim Eun-Kyung,Lee Yun-Jae,Kim Dong-Woung,Shin Sun-Ho,Hwang Sang-Il 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.2
Fever is an elevation of body temperature to a level above normal to greater than $37.2^{\circ}C$. Fever of Unknown Origin is usually defined in adults as continuous fever at least 3 weeks duration with daily temperature elevation above $101.5^{\circ}F(38.3^{\circ}C)$ and remaining undiagnosed after 1 week of intensive study in the hospital. Diagnoses for Fever of Unknown Origin fall into three general categories: infectious disease, connective tissue disease, neoplasm. We experienced a cases of Fever of Unknown Origin which occurred after subarachnoid hemorrhage and intracerebral hemorrhage. As for treatment, we used Cheongleejagamtang-gami(淸離滋坎湯加味). Fever of Unknown Origin was improved within 5 days of the admission.