Carrageenin에 의하여 유발된 백서 슬관절염의 활액막세포에 관한 형태학적 검색

이혜수,심용식,강명재,김상호,Lee, Hye-Soo,Shim, Yong-Shik,Kang, Myoung-Jae,Kim, Sang-Ho 한국현미경학회 1994 Applied microscopy Vol.24 No.3

To investigate the morphology of the synovial lining cells, synovitis was induced by carrageenin injection into the rat knee joint cavities. Synovial membranes were excised at 1, 3, 5, 7 and 14 days, and histologic, electron microscopic, histochemical (periodic acid Schiff: PAS, toluidine blue), and enzyme histochemical (acid phosphatase: ACP, nonspecific esterase: NSE and endogenous peroxidase) studies were performed. The results are as follows: Carrageenin induced synovial membrane hypertrophy with synovial cell proliferation and granuloma formation. The proliferated synovial lining cells and macrophages in the granulomatous lesion had round to oval nuclei and large, plump cytoplasm with many phagocytotic materials and vacuoles. Electron microscopically, these cells had small number of granular endoplasmic reticulum and many lysosomes, phagosomes and vaculoes. Mitotic figures were observed at early stage of experiment. PAS and toluidine blue stains showed strongly positive reaction in the cytoplasm of the proliferated lining cells and macrophages in granulomatous lesion. ACP and NSE activities were strong positive in the cytoplasm of the proliferated synovial lining cells and macrophages in the granulomatous lesion. But endogenous peroxidase stains were negative in all prolifeative lining cells and macrophages in granulomatous lesion. Conclusively, carrageenin-induced synovitis showed proliferation of synovial lining cells and granuloma formation in deep layer. The macrophages, which consisted of the lesions and have active phagocytic function, were speculated to proliferate by mitosis of superficial synovial A cells and histiocytes in the deep layer of the synovial membrane.

원저 : 인체 자궁경부암 (子宮頸部癌) 조직의 Keratin , Herpes Simplex Virus Type 2 , Carcinoembryonic Antigen 및 Lysozyme 에 대한 면역 조직화학적 연구

이혜수(Hye Soo Lee),조성남(Sung Nam Cho),최삼임(Sam Im Choi),최호열(Ho Yeul Choi) 전북대학교 의과학연구소 1991 全北醫大論文集 Vol.15 No.1

자투리 아크릴을 활용한 업사이클링 장신구 디자인 연구

이혜수(Lee, Hye Soo),박보람(Park, Bo Ram) 한국디자인문화학회 2018 한국디자인문화학회지 Vol.24 No.2

국내 업사이클링(Upcycling) 시장이 가파르게 성장하고 있다. 이에 본 연구는 지역 문화를 기반으로 하는 업사이클링 디자인에 주목하여 한국의 간판 제작에 주로 사용되는 아크릴(Acrylic)을 활용한 업사이클링 장신구 디자인 연구를 목적으로 하였다. 문헌연구 방법과 사례연구 방법으로 진행하였다. 먼저 문헌연구를 통해 재활용 패러다임(Paradigm)의 변화와 아크릴의 특성, 한국 간판 동향의 이론적 고찰을 진행하였다. 다음으로 업사이클링을 통한 장신구 디자인의 국내외 사례 9개 중 11개의 업사이클링 장신구디자인을 선정하여 업사이클링 디자인 제작 기법(이루미 등, 2015)으로 분석하였다. 사례 분석 결과 5가지의 업사이클링 디자인 기법 중 Melting and Compressing 기법은 업사이클링 장신구에 활용되지 않았다. 자투리 아크릴을 활용한 업사이클링 장신구의 경우에도 위의 기법을 제외한 나머지 4가지 기법이 적용 가능하였다. 결론적으로 자투리 아크릴의 무독성, 경량성 등의 특성으로 미루어 볼 때 자투리 아크릴은 장신구 디자인 소재로 활용이 적합하였다. 더불어 유광 아크릴의 표면은 장신구의 반짝임을 표현하였다. 본 연구에서는 다양한 업사이클링 기법을 활용한 자투리 아크릴 장신구 디자인 제안하였다. 향후 연구에서는 업사이클링 장신구 디자인의 조형적 연구와 더불어 자투리 아크릴을 활용한 다양한 업사이클링 연구을 기대한다. The domestic upcycling market is growing rapidly. In this regard, this paper aimed to study the upcycling accessory design using offcut acrylics, which is based on the unique sign culture of Korea. The research was conducted through literature research and case study. First, through literature research, theoretical considerations were done based on changes in recycling paradigm, acrylic properties, and trend of Korean sign business. Secondly, 11 upcycling accessory designs out of 9 domestic and international case studies were analyzed based on upcycling product design techniques(Lee, et al, 2015). Lastly, the upcycling accessory designs using offcut acrylics were suggested. As a result, it showed that four out of five upcycling product design techniques were used. Even with the upcycling accessory design using offcut acrylics, Melting and Compressing technique was not used, while the other four techniques were applicable. Through this research, by the non-toxic and lightweight properties of acrylic, the material was suitable to use as an accessory design. In addition, its glossy surface was able to express the glitter of accessories. In the study, a variety of techniques were used to propose the upcycling accessories using offcut acrylics. Furthermore, the study on formative design of the offcut acrylic accessories and various upcycling design studies on offcut acrylics are needed.

다니엘 디포와 근대 개인주의: 『록사나』를 중심으로

이혜수 ( Hye Soo Lee ) 한국근대영미소설학회 2014 근대 영미소설 Vol.21 No.3

This essay intervenes in and complicates the discussion that a distinguishing aspect of Daniel Defoe`s novels lies in their trenchant grasp of modern individualism by reading Roxana. Defoe`s conception and representation of modern individualism in Roxana are not fully explicated by what has been considered the hallmark of his individualism, that is, economic individualism and Protestant interiority. The eponymous heroine of Roxana is, like most hero/ines of Defoe`s other novels, a survivor of adversities and deprivations through her own resources and personal capacity; she seeks to be an autonomous and independent self regardless of the external environments. Yet while Roxana`s hard-acquired autonomy, which is initially predicated on her willful determination to be apart from morality, empowers and enables her to pursue a higher ambition, it also turns out to involve some necessary anxiety, guilty feelings, or self-alienation as the story goes on. The last part of the novel, in which Roxana`s name-sake daughter Susan haunts her and tries to reveal her identity as Roxana, stands as a compelling vignette that shows the nightmarish, repetitive, and unconscious underside of the enlightenment of modern individualism. Defoe`s last novel, the last Susan scene in particular, allows us to see that Defoe`s vision of modern individualism might be much more complex, ambiguous and ambivalent than is usually conceived.

『뉴 아틀란티스』와 『로빈슨 크루소』에 나타난 신대륙에 대한 상상력: 식민주의와 유토피아 사용법

이혜수 ( Hye Soo Lee ) 한국18세기영문학회 2013 18세기영문학 Vol.10 No.1

I examine in this paper how early modern utopian literature involved European colonial imagination for the New world, and how it has historically evolved into a modem utopian novel by reading Francis Bacon`s New Atlantis and Daniel Defoe`s Robinson Crusoe, The New World plays a great role in these texts, which take the South America and the Caribbean Coast as the background of each narrative. The New Atlantis presents the South America, the neighbor country of Bacon`s utopian society of Bensalem, as plato`s “great Atlantis.” Notabaly, however, even though the image of the South America in The New Atlantis is partly overlapped with a legendary continent and that it obliquely reflects European admiration for the newly discovered land the South America is to be conquered by Bensalem and eventually would degenerate into a land of :simple and savage people,” For Bacon`s utopian project embodied in Bensalem lies in building a NEW Atlantis, where formidable and merciless science rules over knowledge, religion, and politics. The purpose of Salomon`s House (an authoritative science research institute in Bensalem) to “enlarge[e]the bounds of Human Empire, to the effecting of all things possible” also shows how Bacon`s scheme for the predomination of science over humanities, like Thomas More`s Utopia is closely related to the imperial conquest of the nature and natives of the New world. while there is a mixture of attraction and contempt about the New World in The New Atlantis and in Robinson Crusoe, a transitional work from utopian literature into the novel, the New World is imagined and represented as an almost entirely naked and savage Other that functions as a sheer object of conquest and transplantation of European culture, The Caribbean desert island in which Crusoe stays for twenty eight years essentially functions as an ``individual utopia`` a space that an individual`s desire met with on rivalry, Even when anther human being comes to his ``individual utopia`` the man who is a Caribbean native and would be called Friday would exist only as an extension of Crusoe`s aggrandized self, In other words, an individual utopia becomes a ``colonial utopia`` in Defoe`s text, Robinson Crusoe manifests how utopian literature, which was initially propelled by a longing for a better community, has been twisted and displaced into an imagination focusing on an individual in the early novel.

초기 영소설과 그로테스크 리얼리즘: 『조셉 앤드류즈』를 중심으로

이혜수 ( Hye Soo Lee ) 한국18세기영문학회 2011 18세기영문학 Vol.8 No.2

This paper examines in what way what Mikhail Bakhtin calls ``grotesque realism`` constitutes a significant part of the realist aesthetics of the early English novel through a reading of Joseph Andrews. Bakhtin advances a term of ``grotesque realism`` in Rabelais and His World as a way to explain an aesthetics that is based on ``the culture of folk humor`` and also involves ``the material bodily principle,`` ``the carnivalesque,`` ``ambivalent and regenerating laugh,`` or ``the grotesque body.`` Bakhtin`s concept of grotesque realism strongly suggests how grotesque aesthetics enacts an important feature in realist aesthetics, which has been narrowly understood as the inheritor of classical aesthetics in numerous discourses on realism. Among the early English novels in which grotesque realism plays a crucial role, Joseph Andrews is noteworthy partly because of its canonical status in the history of the English novel (rather than Gulliver`s Travels or Tristram Shandy). In this essay, I examine, first, how Joseph Andrews began as a parody of Pamela, while parody works as a key word in grotesque realism, and how the famous preface of the text values and theorizes the comic or laughter, another key element in grotesque realism. Secondly, I analyze Parson Adams, a pivotal figure in Joseph Andrews, as a character strongly associated with Sancho who is an embodiment of grotesque realism in Don Quixote, while his Quixotic aspects are satirized. Thirdly, I go through how the narrator of Joseph Andrews undermines his own authority by way of, for example, comparing his book with an inn or "Resting-Place," and then invites the reader into his banquet, rendering the text as a space of carnival and hence grotesque realism.

『워더링 하이츠』와 어른이 된다는 것

이혜수(Hye-Soo Lee) 19세기영어권문학회 2012 19세기 영어권 문학 Vol.16 No.2

In this essay, I read Wuthering Heights as an answer to the generically pivotal question of the novel genre, i.e. what it is for a child to grow up. The issue of growing up or coming of an age is crucial in the novel as it is seen in the central status of Bildungsroman in the nineteenth-century European novel. Wuthering Heights foregrounds the issue of growing-up with its unequivocal focus on childhood or orphanage but it does not take the retrospective view ofa mature adult in its description of the turbulent childhood as often as it happens in most Bildungsromans. Instead, taking the naked view of children who hardly come out of themselves to understand the adult world, it tries to investigate what wecome to be deprived of as we grow up: something ontological such as solidarity or intimacy between two children or one’s narcissistic identification with the other as her/his double. Loss as a condition of growing-up is the particular focus of the first and more important generation in Wuthering Heights. Catherine and Heathcliff achieve a mysteriously close and intimate relationship in their childhood. While Hindley’s degradation of Heathcliff and Catherine’s stay and socialization at Thrushcross Grange illuminate the different class positions of them, their realization that they are two separate individual beings with two separate bodies and sexualities plays not a small role in their separate destinies. Catherine’s proclamation of “I am Heathcliff” reveals her bad faith where she believes that she could be in the same relationship with Heathcliff even when they become adults and she is married to Edgar. While the first generation story of Wuthering Heights implies that growing-up involves an ontological loss, the second generation plot holds quite a normative view that to be an adult means to be mature, to accept a given gender role, or to be reconciled with the symbolic social order. In the second part of Wuthering Heights, Catherine’s daughter voluntarily embraces the female role of care and devotion as it is obvious in her relationship with Linton Heathcliff. On the other hand, Hareton, the liminal figure of Wuthering Heights’s positive imagination, reveals that a child even in a worse condition than Heathcliff’s could hold a desire to be grow up and keep a happy family. While the second generation part unfolds a socially safe and normative view on what it is to grow up, the first generation, whose story presents an idea of growing-up as something of an ontological loss, seems to render Wuthering Heights an everlastingly unforgettable novel. Or, onecompelling feature of Wuthering Heights might lie in its status as an anti-Bildungsroman, which rarely appears in nineteenth-century European realist novels.

『오루노코』와 아프라 벤의 작가성

이혜수 ( Hye-soo Lee ) 한국18세기영문학회 2017 18세기영문학 Vol.14 No.1

Authorship is one of the significant issues in the eighteenth-century studies partly because an author`s self-representation has been hugely altered in that period with the establishment of professional (imaginative) writership along with the cultural shifts from patronage system to literary market or from scribal culture to print culture. In this paper, I examine how the authorship of Aphra Behn, the supposedly first female professional writer in Britain, features in a varied way according to the generic distinctions of play and the new genre of the novel, particularly paying attention to her authorship as a novelist through a reading of Oroonoko. Behn`s authorship as a playwright roughly corresponds to Johnsonian authorship, who argues that writing for bread is an honorable job, as opposed to the Popean myth of author as a hero against literary marketplace. When it comes to the novel, which deals with the contradictory reality of contemporaneity in a “realist” way, however, Behn reveals a distinctive kind of authorship from that of a playwright in heroic drama or Restoration comedy with rigid decorum. She attempts to figure out the place of the novelist as both a passive participant and an active historian/artist, as we see in Oroonoko, who might be helpless in an active intervention in the contemporary reality yet still able to enact empowerment as a writer through her female pen.

소설의 발생 논의 재고 『걸리버 여행기』를 중심으로

이혜수 ( Hye Soo Lee ) 영미문학연구회 2006 안과 밖 Vol.0 No.21

신고전주의와 그 불만 : 스위프트의 『걸리버 여행기』와 「숙녀의 화장방」을 중심으로 Swift`s Gulliver`s Travels and “The Lady`s Dressing Room”

이혜수 ( Hye Soo Lee ) 한국영어영문학회 2007 영어 영문학 Vol.53 No.3