소아 반복성 호흡기 감염의 한약 치료에 대한 임상 연구 동향: 중의학 논문을 중심으로

이지홍,이은주,이보람,장규태,Lee, Ji Hong,Lee, Eun Ju,Lee, Bo Ram,Chang, Gyu Tae 대한한방소아과학회 2016 대한한방소아과학회지 Vol.30 No.2

Objectives The purpose of this study is to investigate recent clinical studies on effect of herbal medicine treatment for recurrent respiratory tract infection in children. Methods We searched some clinical studies about recurrent respiratory tract infection in children from the China Academic Journal (CAJ) of China National Knowledge Infrastructure (CNKI) (January 2011 to December 2015). Results 50 papers were selected from 168 studies. The herbal decoction was main herbal medicine treatment for recurrent respiratory tract infection in children. Commonly used herbs were Atractylodis Rhizoma Alba, Glycyrrhizae Radix, Astragali Radix, Saposhnikovia Radix and Pseudostellariae Radix. Yupingfeng keli was the most frequently used herbal compound. Total effective rate was 66.4-100%, experimental group was significantly higher than control group in 45 papers (P<0.05). Immune index (in 22 papers) and curative effect of TCM syndrome (in 7 papers) were significantly higher than those of control group after treatment (p<0.05). Conclusions Herbal medicine has been shown as an effective treatment on recurrent respiratory tract infection in children. These research results can be utilized in other clinical studies and in treatment of recurrent respiratory tract infection for children.

A Study on the Function Generating Capability of the Fuzzy Controllers

이지홍,정병현,채석,오영석,Lee, Ji-Hong,Chung, Byoung-Hyun,Chae, Seog,Oh, Young-Seok The Institute of Electronics and Information Engin 1992 전자공학회논문지-B Vol.b29 No.7

Fuzzy controllers have been successfully applied to many cases to which conventional control algorithms are difficult to be applied. Even though the representations and the processings of data and information in the fuzzy controller are quite different from those in other control algorithms, the information processing operation that it caries out is basically a function ∫: $A{\subset}R^n{\to}R^m$, from a bounded subset A of an n-dimensional Euclidean space to a bounded subset f[A] of an m-dimensional Euclidean space, where n and m are the number of measured states and the number of control inputs of the controlled system, respectively. Under the assumptions of Mamdani's direct reasoning method and C.O.G.(center of gravity) defuzzification method, the fuzzy controllers are proven to perform the mapping of any given functions f with appropriately defined fuzzy sets. The mapping capabilities of fuzzy controllers are analyzed in detail for two cases, ∫: $R^{1}{\to}R^{1}$ and g: $R^{2}{\to}R^{1}$. Also, it will be shown that the results can be extended to multiple dimensional cases.

알레르기성 자반증의 증례보고 1례

이지홍,유선애,이승연,Lee, Ji-Hong,Yu, Sun-Ae,Lee, Seung-Yeon 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.3

Objectives The purpose of this study is to report the clinical effects of an oriental medical treatment on the patient with allergic purpura. Methods A 7-year-old female patient, who was suffering from the purpura on her extremities: swelling and arthralgia on her lower extremities, was treated by herb medicine, acupuncture and pediluvium. Results Treated only with oriental medicine, the patient's allergic symptoms were improved. When we checked back on her condition after 2 months later, she did not show any recurrence of the flares, and regained her health. Conclusions This study shows that oriental medical treatments are effective on allergic purpura, but further clinical studies are needed.

신경 최적화 회로망을 이용한 두 대의 로보트를 위한 최소시간 충돌회피 경로 계획

이지홍,변증남,Lee, Ji-Hong,Bien, Zeung-Nam 대한전자공학회 1990 전자공학회논문지 Vol. No.

공간상에 움직여야할 길이 주어진 두 대의 로보트의 속도계획 문제를 두 단계의 부문제로 나누어 각각의 독립적으로 다루는 방법을 도입하여 최소시간 속도계획 방법을 제안하였다. 제안된 방법은 i) 로보트가 각자의 길을 따라 이동한 거리를 두 축으로하는 코오디네이션 공간이라는 2차원 공간을 구축하고 이공간상에서 충돌을 피할 수 있도록 코오드네이션 곡선을 선정하고, ii)선정된 곡선을 따라 최소시간을 보장하는 속도계획을 하는 두 단계의 문제중 두 번째 단계의 문제에 대해 로보트의 동력학 및 각 관절의 최대 회전속도등을 고려하여 최적해를 구하는 방법을 제안하였다. 또한 신경 최적화 회로망의 이론을 응용하여 간단한 반복 계산 알고리듬으로 최적해를 구하였다. 제안된 방법은 두 대의 SCARA형 로보트의 경로계획의 예로 시뮬레이션하여 유용성을 보였다. A collision-free trajectory planning for two robots with designated paths is considered. The proposed method is based on the concept of decomposing the planning problem into two steps: one is determining coordination of two robots, and the other is velocity planning with determined coordination. Dynamics and maximum allowable joint velocities are also taken into consideration in the whole planning process. The proposed algorithm is converted into numerical calculation version based on neural optimization network. To show the usefulness of proposed method, an example of trajectory planning for 2 SCARA type robot in common workspace is illustrated.

A Tuning Method for the Membership Functions of a Fuzzy Controller

이지홍,채석,오영석,Lee, Ji-Hong,Chae, Seog,Oh, Young-Seok The Institute of Electronics and Information Engin 1993 전자공학회논문지-B Vol.b30 No.4

It is known that the performance of a fuzzy controller is related with fuzzification method, inference rules, defuzzification method, and linguistic variables. Among these, generally, the linguistic variables and control rules are transfered to control engineers from an expert or experts of the controlled system and other parts are designed by control engineers. However, there may be some missed infirmations or uncertainties in the transfered data. The purpose of the paper is to propose an algorithm to tune the membership functions of initially given fuzzy sets To do so, a simple shape of the membership fuction is assumed for the fuzzy sets, and the relations between the shapes of the fuzzy sets and the performance of the control system is derived. According to the relations, the shape of the membership functions are modified during operation of the whole system. The proposed algorithm will be applied to two emample plants, type 1 and type 0 systems.

한우 암소의 생체 초음파 성적을 이용한 유전모수 추정

이지홍,여정수,Lee, Ji-Hong,Yeo, Jung-Sou 한국데이터정보과학회 2011 한국데이터정보과학회지 Vol.22 No.6

지금까지 한우의 유전능력 개량은 수소 위주로 이루어져 왔으나, 최근 암 수소 동시개량을 위하여 많은 연구가 진행 중에 있다. 본 연구에서는 암소의 유전능력 개량을 위하여 생체 초음파 단층 촬영기법을 이용하여, 주요 경제형질에 대한 유전적 효과를 측정하였다. 한우 암소 1,648두의 생체 초음파 단층촬영 결과를 이용하여 측정시 암소의 사육월령, 측정지역, 신체충실지수의 효과를 일반 선형모형을 이용하여 조사하였다. 한우 암소의 초음파 측정시 사육월령별 초음파 성적은 50~60개월령의 등심단면적, 등지방두께, 근내지방도 성적에서 유의적으로 높게 나타나 이 시기가 암소의 발육이 가장 높은 시기로 판단된다 (P<0.05). 그리고 지역별 암소의 초음파 성적은 C 지역이 신체충실지수, 등심단면적, 등지방두께가 높게 나타났으며, J지역은 근내지방도가 가장 낮게 나타났다 (P<0.05). 신체충실지수가 높을수록 등심단면적, 등지방두께, 근내지방도 성적이 높게 나타났다. 제한최대우도법으로 유전모수를 추정한 결과 유전력은 등심단면적이 0.136, 등지방두께가 0.351, 근내지방도가 0.236으로 나타났다. 이러한 초음파를 이용한 유전모수 추정결과는 수소 거세우의 도체성적을 이용한 유전모수 추정결과에 비하여 낮게 나타났지만, 도축을 하지 않은 암소의 유전능력 개량을 위해서는 반드시 필요한 기초자료라 판단된다. This study was conducted to estimate genetic effects on economically important traits for genetic improvement in Hanwoo by using the real-time ultrasound measurements for longissimus dorsi muscle area (LMA), backfat thickness (BFT), and marbling score (Marb). The phenotypic data were obtained from 1,648 pedigreed cows, and general linear models were applied to test the effects of age, region, and body condition socre. The cows between 50 and 60 months of age had the greatest scores for LMA and BFT, and Marb (P<0.05). The cows in region C had the greatest scores for body condition socre, LMA and BFT, while in region J Marb was the lowest (P<0.05). There was positive relation with LMA, BFT, and Marb according to increase body condition socre. Heritabilities for LMA, BFT, and Marb were estimated as 0.136, 0.351, and 0.236, respectively. These results would provide primary information for the efficient implementation of genetic improvement schemes in Hanwoo.

소아 말초성 안면신경마비 환자 5례에 대한 증례 보고

이지홍,유선애,이승연,Lee, Ji Hong,Yu, Sun Ae,Lee, Seung Yeon 대한한방소아과학회 2013 대한한방소아과학회지 Vol.27 No.3

Objectives The purpose of this study is to report the clinical effects of Korean medical treatments on peripheral facial palsy. Methods In this study, 5 children were treated with peripheral facial palsy with Korean medical treatments, such as herb medicines, acupunctures, electro-acupuncture, and infrared therapy. Results As a result of the treatment, 5 children were almost recovered. The average treatment period was 42.17 days, with average recovery period of 9 weeks. Conclusions This study shows that Korean medical treatments on childhood peripheral facial palsy could be one of the viable options for this patient kind.

한약 복용 후 발생한 유해사례에 대한 연구 - 소아·청소년을 중심으로

이지홍,유선애,이승연,Lee, Ji Hong,Yu, Sun Ae,Lee, Seung Yeon 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.3

Objectives The purpose of this study is to investigate the incidence and clinical features of adverse events associated with herbal medicine, and to analyze their causality and severity. Methods This study was carried out from 159 children and adolescents who took herbal medicine in the Department of Pediatrics, ${\bigcirc}{\bigcirc}$ Korean Medical Hospital from december, 2013 to april, 2014. The data was collected by survey in person or telephone. The World Health Organization (WHO)-Uppsala Monitoring Center (UMC) criteria was used to analyze causality for each adverse events. Results 1. 207 cases were surveyed from 159 children and adolescents who took one or more kinds of herbal medicine. 2. A total of 12 general adverse events (5.8%) were reported from the study. Among these adverse events, 8 cases (3.9%) were associated with herbal medicine. 3. Gastro-intestinal system disorders were most frequently reported (70%) as adverse events, which is followed by psychiatric disorders (15%), skin and appendages disorders (10%), urinary system disorders (5%). 4. The most common clinical symptom was abdominal pain (20%), followed by diarrhea (15%), loose stools (10%), vomiting (10%) and borborygmus (10%). 5. The severity of adverse drug reactions was mostly mild (87.5%), and moderate (12.5%). There was no severe case. Conclusions The adverse events from herbal medicine on children and adolescents were mostly minor, most of them could continue herbal medicines.

Erythronychia 소견을 보이는 표재성 말단부 섬유점액종 1예

이지홍 ( Ji Hong Lee ),원영호 ( Young Ho Won ),이승철 ( Seung-chul Lee ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee-bum Lee ) 대한피부과학회 2019 大韓皮膚科學會誌 Vol.57 No.9

흉선종의 악화와 관련된 이식편대숙주병 양상의 홍피증

이지홍 ( Ji Hong Lee ),이지범 ( Jee-bum Lee ),이승철 ( Seung-chul Lee ),윤숙정 ( Sook Jung Yun ) 대한피부과학회 2020 大韓皮膚科學會誌 Vol.58 No.9

Thymoma-associated multiorgan autoimmunity (TAMA) is a rare paraneoplastic disease defined as thymomas with liver, intestine, or skin manifestations, resembling graft-versus-host disease (GVHD) histopathologically in the absence of hematopoietic stem cell transplantation. A 76-year-old woman who had been diagnosed with invasive thymoma presented for evaluation of erythematous scaly papules across the trunk and extremities. Histopathological findings revealed parakeratosis, many apoptotic cells in the epidermal layer, and perivascular and interface dermatitis with lymphocytic infiltration. These pathologic alterations were similar to those observed in GVHD. Interestingly, she had never undergone allogenic stem cell or solid-organ transplantation. Based on her medical history and the presence of GVHD-like skin symptoms, we suspected that the cutaneous lesions may have been related to aggravation of the thymoma. We report this rare and interesting case for educational purposes because such a case has never been reported in Korea before. (Korean J Dermatol 2020;58(9):624∼627)