EAF 더스트-점토계의 중금속 용출 및 안정화에 미치는 pH의 영향

이지영,이기강,김유택,강승구,김정환,Lee, Jee-Young,Lee, Ki-Gang,Kim, Yoo-Taek,Kang, Seung-Gu,Kim, Jung-Hwan 한국결정성장학회 2006 韓國結晶成長學會誌 Vol.16 No.2

유해한 중금속을 다량 함유하는 EAF(electric arc furnace) 더스트를 세라믹 원료로 재활용하기 위해서 EAF 더스트, EAF 더스트-점토에 대해서 pH와 혼합비에 따른 중금속 용출농도의 변화를 분석하였다. 소성과정 중에서 발생하는 중금속의 휘발량을 소지 내의 중금속 이온의 총량을 측정하여 평가하였으며 TCLP(toxicity characteristic leaching procedure)분석을 통해 중금속 이온의 안정화 정도를 평가하였다. EAF 더스트-점토 슬러리의 pH를 10으로 조절하였을 경우에 습식혼합 여액중의 중금속 이온의 농도가 가장 낮은 값을 가졌다. pH 10의 슬러리에 대해서 혼합비와 소성온도에 따른 소지내 중금속 이온의 총량을 측정한 결과 소성온도와 EAF 더스트의 함량이 증가할수록 중금속의 휘발이 증가하였으며, 점토의 혼합비가 증가할수록 중금속 이온의 휘발이 억제되었다. TCLP 분석결과 점토의 혼합비와 소성온도가 증가할수록 중금속의 용출은 감소하였으며 중금속의 용출농도는 기준치 이하로 안정화되었음을 확인할 수 있었다. To recycle the electric arc furnace (EAF) dust as a ceramic raw materials, the leaching concentrations of heavy metals (Zn, Pb, Cr, Cd) were analysed with various pH and mixing ratios for EAF dust and EAF dust-clay mixtures. The evaporation amounts of the some heavy metals were evaluated by measuring their total concentrations in the sintered bodies of EAF dust-clay mixtures with various mixing ratio and sintering temperature. Toxicity characteristic leaching procedure (TCLP) test was conducted for evaluating the chemical stabilities of the heavy metal elements. Leaching concentrations of heavy metal ions shows minimum leaching concentration at the pH 10. Evaporation amount of heavy metals in the sintered bodies were evaluated for the mixtures of pH 10 depenidng on mixing ratio and sintering temperature. Evaporation of heavy metal components were increased with increasing the sintering temperature and contents of the EAF dust. The evaporation of the heavy metal components in EAF dust was effectively suppressed by increasing the clay content. The leaching concentrations of heavy metal components were decreased with increasing clay content and temperature.

점토와 전기로 제강분진의 콜로이드/계면 특성 분석

이지영,이기강,김유택,강승구,김정환,Lee, Jee-Young,Lee, Ki-Gang,Kim, Yoo-Taek,Kang, Seung-Gu,Kim, Jung-Hwan 한국결정성장학회 2006 韓國結晶成長學會誌 Vol.16 No.2

중금속 이온의 용출거동은 콜로이드/계면 성질에 의존하는데, 이를 알아보기 위해 ICP와 SEM 분석을 하였다. 전기로 제강분진에 포함된 중금속은 '양쪽성 금속'으로 pH 10에서 중금속이 가장 적게 용출되는 것을 알 수 있었고 pH 8보다 pH 12에서 중금속 이온이 상당량 용출되어 나왔다. 그리고 전기로 제강분진에 점토를 첨가함으로써 중금속 이온의 용출이 감소하는 것을 알 수 있었다. 특히 pH 12의 경우에 pH 8에 비해서 중금속 이온의 용출이 큰 폭으로 감소하였으며 콜로이드계면 성질 관찰 결과, 점토의 경우 pH 12에서 점토에서 녹아나온 Si 수화물이 점토 입자표면을 둘러싸고 있음을 관찰할 수 있었다. 전기로 제강분진과 점토의 혼합 슬러리에서 pH 8의 경우보다 pH 12에서 중금속 이온의 농도가 크게 감소한 것은 PSHP의 형성에 의한 것으로 사료된다. The leaching behavior of heavy metal ions with pH and colloid/interface property was analyzed by ICP and SEM. The heavy metals in EAF dust are 'amphoteric metal' and the heavy metal ions leached a little at pH 10. And the leaching concentrations of heavy metals at pH 12 were higher than the that at pH 8. The leaching concentrations of heavy metal ion were decreased with adding the clay to the EAF dust. Especially, the leaching concentrations of heavy metal ion were effectively decreased at pH 12. The observation of colloid/interface properties shows that the soluble silicon hydroxide from clay at pH 12 was precipitated at the surface of the heavy metal and clay particles. This silicon hydroxide precipitates were named the PSHP. The leaching concentrations of heavy metal ion were effectively decreased by the formation of PSHP when adding the clay to the EAF dust and controlling the pH of the slurry at 12.

진행성 대장직장암 환자군에 있어서 5-FU 혹은 capecitabine의 최적 시간 치료법에 대한 체계적 고찰 : 메타분석

이지영,오혜경,류한성,윤성우,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Yoon, Seong Woo 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.1

Background : The purpose of this study is to investigate the efficacy and safety of the circadian delivery schedule of fluorouracil or capecitabine based chemotherapy for advanced colorectal cancer. Patients and methods : A meta-analysis was performed using individual data from eight international randomized clinical trials, especially phase II or III trials, comparing 5-fluorouracil, or capeticabine in chronomodulated or conventional schedule. The data from 8 studies was composed of 692 patients receiving chronomodulated chemotheray and 684 patients receiving conventional chemotherapy. The main end point was response rate. Results : Response rate was insignificantly different from each group (RR 1.14, 95%CI 0.74-1.74, p=0.55). Overall survival and progresseion-free survival were not significant either. Chemotherapy induced anemia, diarrhea, and nausea/vomiting were worse in the chronotherapy group, with statistic significance respectively. On the other hand, chemotherapy induced thrombocytopenia, stomatitis, peripheral neuropathy, and dermatotoxicity were better but they were not statistically significant results. Conclusions : Patients lived longer but not significantly on chronomodulated chemotherapy rather than on conventional chemotherapy. Patients on chronomodulated chemotherapy experienced adverse events more. The chronomodulated chemotherapy schedule needs adjustment of its delivery schedule and further research is required.

온백원이 암세포에 미치는 항암활성 효과

이지영,오혜경,류한성,김남재,정원용,오현아,최혁재,윤성우,류봉하,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Kim, Nam Jae,Jung, Won-Yong,Oh, Hyun-A,Choi, Hyuck Jai,Yoon, Seong Woo,Ryu, Bong-Ha 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.2

Objective : The objective of this study was to investigate the experimental efficacy of anti-tumor activity of the complexed herbal formula, Onbaekwon (OBW), which was derived from the literature of Traditional Korean Medicine, Dongeuibogam. Methods : Nine Cancer cell lines, LoVo, MCF-7, HepG2, AGS, A549, NCI-H69, HL-60, Sarcoma 180, LL/2, were prepared and the cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2yl)-2,5-dephenyl tetrazolium bromide (MTT) assay. Four of them, NCI-H69, HL-60, Sarcoma 180, and LL/2, showed strong cytotoxic activities and they were additionally undergone flow cytometry to find out their effects on apoptosis. ICR male mice were implanted with Sarcoma 180 intraperitoneally and divided into 8 species for each group. Control group was treated with normal saline, positive control group was treated with cyclophosphamide 8mg/kg, and experimental group was treated with OBW 1 g/kg. Results : Among 9 cancer cell lines, NCI-H69, HL-60, Sarcoma 180, and LL/2, expressed less than 0.10 mg/ml of $IC_{50}$ under 0.1~1mg/ml of OBW. NCI-H69, HL-60, Sarcoma 180, and LL/2, showed dose-dependent efficacy of apoptosis. When Sarcoma 180 cancer cell was implanted in ICR male mice and treated with the OBW, they prolonged the median overall survival for 0.8 days, from 17.5 to 18.3. Conclusion : OBW showed strong cytotoxicity to some cancer cells, which are NCI-H69, HL-60, Sarcoma 180, and LL/2, and its apoptotic activity was dose-dependent. OBW prolonged the median survival of mice implanted with Sarcoma 180. Further researches would be expected to support the efficacy of OBW.

해암단이 수종의 암세포에 미치는 항암 효과

이지영,오혜경,류한성,김남재,정원용,오현아,최혁재,윤성우,류봉하,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Kim, Nam Jae,Jung, Won-Yong,Oh, Hyun-A,Choi, Hyuck Jai,Yoon, Seong Woo,Ryu, Bong-Ha 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.2

Objective : The objective of this study was to investigate the anti-tumor activity of the complexed herbal formula, Haeamdan (HAD). Methods : Seven Cancer cell lines, LoVo, MCF-7, AGS, Sarcoma 180, HL-60, NCI-H69, LL/2, were prepared and the cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2yl)-2,5-dephenyl tetrazolium bromide (MTT) assay. HAD was applied with various concentrations from 0.1 to 1.0 mg/ml to figure out the appropriate dosage. ICR male mice were intraperitoneally implanted with Sarcoma 180 and divided into 8 species for each group. Control group was treated with normal saline, positive control group was treated with cyclophosphamide 8mg/kg, and experimental group was treated with HAD 1g/kg. Results : Among seven cancer cell lines, HAD exhibited strong cytotoxic activities to followed four cancer cell lines, that is, Sarcoma 180, HL-60, NCI-H69, and LL/2. These cytotoxic activity was expressed under 0.50 mg/ml of IC50 under 0.1~1mg/ml of OBW. When Sarcoma 180 cancer cell was implanted in ICR male mice and treated with the HAD, HAD prolonged the median overall survival for 3.6 days, from 17.5 to 21.1 days. Conclusion : HAD showed strong cytotoxicity to the cancer cells, Sarcoma 180, HL-60, NCI-H69, on in vitro study and it showed anti-tumor activity in vivo with the peritoneal cancer mice by prolonging the median survival for 3.6 days. Further researches would be expected to support the anti-tumor efficacy of HAD.

개 심장사상충 추출액 투여에 의한 Anaphylactoid Reaction

이지영,송근호,권현주,김명철,윤효인,김덕환,Lee, Jee-young,Song, Kun-ho,Kwon, Hyun-ju,Kim, Myung-cheol,Yun, Hyo-in,Kim, Duek-hwan 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.3

This study was performed to clarify the induction possibility of anaphylactoid reactions by the administration with the heartworm extracts, and, if any, to elucidate different virulences in terms of the protein concentrdtions and sexes of Dirofilaria immitis. Twenty three clinically healthy D. immitis-free adult dogs were used in the present study. The experimental animals were divided into 5 groups. Group A (5 heads) was administered with an female heartworm extract containing 0.1 g/dl protein concentration. Group B (4 heads) was administered with an male heartworm extract containing 0.1g/dl protein concentration. Group C (5 heads) was administered with an female heartworm extract containing 0.2 g/dl protein concentration. Group D (4 heads) was administered with an male heartworm extract containing 0.2 g/dl protein concentration. Group E (5 heads) was administered with an female heartworm extract containing 0.4 g/dl protein concentration. The changes of clinical symptoms and vital signs (body temperature, heart rate and respiration rate) were examined before and 5 minutes, 15 minutes, 30 minutes, 1 hour, 2 hours and 24 hours after injection with the extracts, respectively. In addition, the changes of hematological values (RBC, PCV and total leukocytes counts), serum chemical values (ALP and CK) were determined. It was considered that heartworm extract could induce anaphylactoid reaction and adult female heartworm extract was more affective than those of adult male heartworm extract in the changes of clinical symptoms, vital signs, hematological values and serum chemical values.

질적연구를 통해서 본 국내 여성전문병원에서의 일과 가정의 상호작용

이지영(Jee Young Lee),김효선(Hyo Sun Kim) 한국경영학회 2014 Korea Business Review Vol.18 No.3

본 연구에서는 일과 가정의 영역간의 상호작용이 구체적으로 어떻게 이루어지고 있는지를 살펴보기 위해, 국내 S 여성병원 26명의 인터뷰를 바탕으로 질적으로 분석함으로써 일-가정 상호작용의 세 가지 영역인 일-가정 갈등, 일-가정 촉진, 일-가정 경계관리의 내용을 해석적 현상학적 분석을 통해 분석하였다. 그 결과, 기존의 해외 연구들의 결과와 동일하게 행동에 기초한 갈등의 구체적인 내용은 나타나지 않았으며, 시간에 기초한 갈등과 긴장에 기초한 갈등에 대한 구체적인 내용들이 도출되었다. 특히 일-가정 촉진에서는 한국의 특수한 맥락을 반영한 내용이 도출되었는데, 우리나라의 경우 여성이 직업을 갖는 것이 가정의 시댁 및 자녀와의 거리감을 갖게 해주어 심리적인 측면에서 긍정적인 상호작용을 나타내며, 또한 식구들의 자립심 형성, 다른 사람과의 인간관계 학습에 도움이 된다는 내용이 도출되었다. 마지막으로 경계관리의 내용분석에서는 전문직 여성의 경우 아이의 양육이 여성에게 많은 부분 부담 지어지는 한국의 상황에서 자녀의 생애주기에 따라 수년간의 시간적 간격을 두고 장기간 분리전략을 사용하였으며, 어떠한 경우에는 먼 거리에 있는 친인척에게 아이를 맡기는 장거리 분리전략을 사용하는 것이 특징으로 발견되었다. 본 연구에서 도출된 연구 결과들은 일-가정 상호작용의 새로운 연구 가설 가능성과 한국적 맥락에서 시사점을 보여 주었다는데 의미가 있다 할 수 있다. In order to investigate how work interacts with family in the Korean organizational context, this study conducted a qualitative study regarding three main topics of work- family issues: work-family conflict, work-family facilitation and work-family boundary management. Based on the 25 interviews at S women hospital, we confirmed previous studies, yet found some unique issues that reflect Korean context. Similar to the findings of previous studies, the results didn`t show the behavior-based conflict but discover time-based conflict and strainbased conflict. In particular, there are more work-to-family conflicts when the people have strong career aspiration. In the case of work-family positive interaction, Korean women who have jobs feel happy because they can maintain proper distance with their children and parents-in-law. Moreover, participants reported that people can have different perspectives and expand their viewpoint about human being by talking with their family. This was especially prominent among people who were in the leadership role. Finally, this study revealed both segregation strategy and integration strategy. On the one hand, some people pursued long-distance segragation strategy which had long term effect in family life. On the other hand, some pursued integration strategy, in which success depended on supporting system and relevant policy initiatives in the future. These results have meaningful implications to show new research hypothesis which could be tested in Korea organization setting.

초기 청소년의 인터넷 게임을 통한 사이버공간 경험

이지영(Jee Young Lee) 대한스트레스학회 2011 스트레스硏究 Vol.19 No.3

본 연구는 초기 청소년의 인터넷게임을 통한 사이버공간 경험의 본질적 의미를 탐색하기 위해 수행되었다. 연구자료는 인터넷게임 일반사용자 군에 속하는 6명의 남, 녀 초, 중학생을 대상으로 개방적이고, 반구조적인 질문형식을 사용한 1-2회의 심층면담을 통해 수집하였고, Giorgi(2000)의 현상학적 연구방법을 적용하여 분석하였다. 인터넷게임을 하는 초기 청소년의 사이버공간 경험의 구성요소로 [정서적 욕구에 대한 기대], [가용한 놀이공간으로 인식], [게임에서의 승리와 인정으로 인한 만족감], [가상현실의 실현으로 인한 대리만족감], [사이버 자아와의 동일시와 애착], [가상현실감과 매개된 실재감], [인터넷게임 행동의 반복과 갈망]이 도출되었다. 구성요소들 간의 관계를 통해 나타난 인터넷게임을 하는 초기 청소년의 사이버공간 경험의 일반적 구조는 [정서적 욕구에 대한 기대]가 심리적 차원의 원인적 요소로 나타났고, [인터넷게임 행동의 반복과 갈망]이 행위적 차원의 결과적 요소로 나타났으며, 이러한 인과적 관계는 순환적 특성을 나타내었다. 또한, 이들은 인터넷게임을 통한 사이버공간을 [가용한 놀이공간으로 인식]하는 인지적 차원의 매개를 거치며, 이들이 경험하는 [게임에서의 승리와 인정으로 인한 만족감], [가상현실의 실현으로 인한 대리만족감], [사이버 자아와의 동일시와 애착], [가상현실감과 매개된 실재감]은 결과적 요소인 [인터넷게임 행동의 반복과 갈망]에 촉진적 요소로 작용하는 것으로 나타났다. 본 연구는 인터넷게임을 하는 초기 청소년들이 겪는 사이버공간 경험의 구성요소와 일반적 구조를 순환적 방법으로 분석함으로써 그 심리적 기전을 밝히려는 시도를 한 것으로 그들의 사이버공간 경험에 대한 심리적, 행위적 특성에 대한 이해의 폭을 넓히고, 나아가 정신건강 교육과 중재의 참고자료로 활용할 수 있다는 데 그 의의가 있다. The purpose of this study was to understand and explore the cyberspace experience of internet game among early adolescents. A phenomenological research method guided data collection and analysis. Study participants included 6 elementary and middle school students who had experienced cyberspace of internet game. Data were collected through individual in-depth interviews. All interviews were audio taped and transcribed verbatim. Coding was used to establish different concepts and categories. The results of this study are following. These common constituents were found: expectation for emotional need; recognition of available playground; satisfaction from achievement in the virtual space; vicarious satisfaction to impossibility in the real space; attachment with cyber-self; connected tele-presence to virtual reality; and the craving for staying on the cyberspace. The structure of cyberspace experience of internet game was derived from the 7 constituents. Expectation for emotional need was identified as a cause in the psychological dimension. And the craving for staying on the cyberspace was identified as a result in the behavioral dimension. This relationship of cause and result moved in a cycle through the medium of recognition about the cyberspace as a available playground. Furthermore, satisfaction from achievement, vicarious satisfaction to impossibility, attachment with cyber-self, connected tele-presence to virtual reality facilitated the craving for staying on the cyberspace. The results of this study may enlarge the knowledge about the cyberspace experience of internet game and contribute to health professionals to understand early adolescents with cyberspace experience of internet game. (Korean J Str Res 2011;19:221∼229)

초음파 영상을 통한 태아의 모습 제공 여부가 임부의 태아 애착에 미치는 영향

이지영 ( Jee Young Lee ),조정연 ( Jeong Yeon Cho ),장순복 ( Soon Bok Chang ),박주현 ( Ju Hyun Park ),이영호 ( Young Ho Lee ) 여성건강간호학회 2002 여성건강간호학회지 Vol.8 No.3

한국과 호주 청소년들의 SNS 이용과 온라인 사회적 자본

이지영 ( Jee Young Lee ),박소라 ( Sora Park ),나은영 ( Eun-yeong Na ),김은미 ( Eun-mee Kim ) 서강대학교 언론문화연구소 2014 언론문화연구 Vol.21 No.-

본 연구는 청소년들의 SNS 이용이 한국과 호주 청소년들의 온라인 사회적 자본 형성에 어떠한 관련이 있는지, 상이한 문화적 배경을 지니고 있는 두 국가 간의 비교 연구를 통해 알아보고자 했다. 이를 위해, 12∼15세 청소년을 대상으로 2013년 4∼10월에 한국(644명)과 호주(401명) 주요 도시에서 면대면 조사를 실시하였다. 본 연구는 SNS 이용방식(자기노출, 소셜모니터링, 정보공유, 대인커뮤니케이션, 집단활동)과 온라인 사회적 자본(결속 및 연계)을 측정하여 분석한 결과, 전반적인 SNS 이용량에는 큰 차이가 없는 반면, 이용 유형별 이용 정도에는 두 국가 간 뚜렷한 차이가 있었다. 호주 청소년들은 한국 청소년에 비하여 집단활동을 더 많이 하는 반면, 한국 청소년의 경우, 소셜모니터링 활동을 더 많이 하는 것으로 나타났다. 두 국가의 인지된 온라인 사회적 자본 또한 차이를 보였다. 호주 청소년이 한국 청소년 대비 연계 사회자본을 더 높게 인식하고 있는 것으로 나타난 반면, 결속 사회자본에서는 유의미한 차이가 나타나지 않았다. 둘째, SNS 이용이 온라인 사회적 자본 인식에 미치는 영향을 알아본 결과, 한국의 경우 대인 커뮤니케이션 및 집단활동 정도가 모두 결속 및 연계자본에 정(+)적 영향을 미치는 주요 변인으로 도출되었다. 반면 호주는 결속자본에는 소셜모니터링, 대인 커뮤니케이션, 집단 활동이 모두 정(+)적 영향을 미치는 반면, 연계자본에는 정보공유와 대인 커뮤니케이션 이용 정도가 정(+)적 영향을 미치는 것으로 나타났다. 대인 커뮤니케이션 변수는 두 국가 모두 온라인 사회적 자본에 영향을 미쳤다. The aim of this study was to identify the different contexts of SNS use and its impact, comparing SNS use and perceived online social capital between Australian adolescents and Korean adolescents. A face-to-face survey of adolescents (12 to 15 year-olds) was conducted in major cities in Korea (N=644) and Australia (N=401). Types of SNS use and both online bonding and bridging social capital were measured There was no significant difference in time spent on SNS between the two countries’ adolescents; however, significant differences in the way adolescents use SNS were found. Australian adolescents tended to use SNS for group activities, whereas Koreans used it for social monitoring. For online social capital, Australian adolescents’ perceived social capital was higher in bridging capital, whereas no significant difference in bonding capital was found. Hierarchical regression analyses revealed the types of SNS use were related to how the adolescents perceived of their social capital, both online and offline. SNS use predicted online social capital in both countries, but its contribution differed based on countries. For Australian adolescents, using SNS for social monitoring, interpersonal communication and group activities were related to higher bonding capital. Using SNS for interpersonal communication and group activities were positively related to bonding capital among Korean adolescents. Australian’s bridging capital was related to their SNS uses for information sharing and interpersonal communication, whereas among Koreans, interpersonal communication and group activities were related to their bridging capital. Interpersonal communication contributes significantly to both bonding and bridging capital in the two countries.