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쌍극 소작기로 손상을 가한 백서 신동맥의 병리조직학적 변화에 대한 실험적 연구
이상구,박철완,김광명,김영수,고용,오성훈,오석전,김남규,정환영,이중달 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.7
The bipolar coagulator has been frequently used in reducing the size of aneurysmal neck or dissecting the aneurysmal sac. However the effects of bipolar current on the wall of vessels have not been adequately documented. The author studied the histopathological changes of the renal arterial wall after bipolar coagulation. Thirty one Sprague-Dawley strain rats of both sexes and of various age were used. Under penthobarbital anesthesia, the left renal artery was coagulated with bipolar forcep just distal to it's origin from the aorta. The rats were divided into two groups : Group A was coagulated for two seconds : Group B for one second. The coagulation sites of vessels were examined grossly and microscopically in three and six months, respectively. The results were summerized as followings : 1) In both three and six months groups : the internal elastic membrane and elastic fibers were destructed, fragmented and thinned ; the medial smooth muscle cells were damaged and decreased in number. 2) While the endothelial cells were severely desquamated and scattered in three months group, but there was an evidence of partial regeneration of endothelium and reduction of inflammatory reaction in six months group. Fibrosis was more augmented in six month group than three month group. 3) Between group A and B. There seemed to be no definite discrepancy in histopathological findings. 4) Pseudoaneurysms were developed in 72.2% of three months group and in 61.5% of six months group, but there was no significant statistical difference in the rate of pseudoaneurysm formation between the two groups(p>0.05, ??=0.393). 5) Above findings suggest that the pseudoaneurysm which might be produced by bipolar coagulation of vessels in the neurosurgical operation, would be progressed to the true aneurysm if continuous hemodynamic factors are exerted upon the pseudoaneurysm. Therefore, it is desirable that the bipolar current should be used very catiously during the surgery of cerebrovascular disease.
조수현,김승룡,조삼현,황윤영,김경태,신중식,이중달,유중배,전석훈 대한부인종양 콜포스코피학회 1996 Journal of Gynecologic Oncology Vol.7 No.3
The primary malignant tumor of the peritoneum also known as primary peritoneal carcinoma or primary peritoneal papillary serous carcinoma is rare and involves the peritoneum, especially the pelvic peritoneum of female patients. It is difficult to differentiate histologically between papillary mesothelioma, primary ovarian tumor and primary peritoneal carcinoma. We report two cases of the primary peritoneal carcinoma with clinical presentation and histologic characteristics.