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류지호,이주희,김낙인 ( Ji Ho Ryou,Ju Hie Lee,Nack In Kim ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.6
Background: Glomus tumor is a benign lesion composed of vessels and glomocytes in varying proportions. Although the histc)logic features of glomus tumors by light microscopy are characteristic and well recognized, there is controversy as to the histogenesis and cytological characterization of the glomus cell. Objective : The aim of the present study was to verify the histopathological origin of a glornus tumor. Method: We investigated 1 cases of glomus tumors for immunohistochemical features. Results : The glomus turnor cells were negative when stained for FactorVIII - related antigen and S-100 protein. Conversely, all materials were found to be positive for actin, vimentin, NSE. Sorne exhibited an equivocal reaction for desmin and CD34, the rest were negative. Conclusion : These findings support the hypothesis that the glomus cell is transitional-between smooth mu.cle and vascular ndothelium-being essentially a modified smooth muscle cell with some endot.helial cell properties (KoreaA J D8rmatOI 1997;35(6): 1130-1135)
흉수에 전이된 난소의 Sex Cord Tumor with Annular Tubules(SCTAT)의 세포학적 소견 - 1예 보고 -
이선,이주희,김윤화,박용구,장학순,양문호,Lee, Sun,Lee, Ju-Hie,Kim, Youn-Wha,Park, Yong-Koo,Chang, Hak-Soon,Yang, Moon-Ho 대한세포병리학회 1997 대한세포병리학회지 Vol.8 No.2
The sex cord tumor with annular tubules(SCTAT) is a rare ovarian neoplasm, which charateristically shows simple and complex annular tubules with central acidophilic hyaline bodies. This tumor has been considered as a tumor of low-grade malignancy with late recurrence. We presented a brief case report of metastatic SCTAT of ovary in pleural fluid from ovary with cytopathologic and clinical features. The cytologic features of differential diagnosis are discussed.
요 세포 검사의 진단적 가치; 액상세포검사와 고식적 방법의 비교
이선,박정희,도성임,김윤화,이주희,장성구,박용구,Lee, Sun,Park, Jung-Hee,Do, Sung-Im,Kim, Youn-Wha,Lee, Ju-Hie,Chang, Sung-Gu,Park, Yong-Koo 대한세포병리학회 2007 대한세포병리학회지 Vol.18 No.2
Urine cytology is an important screening tool for urinary tract neoplasms. Liquid-based preparation methods, such as $ThinPrep^{(R)}$, have been introduced for non-gynecological samples. We aimed to assess the diagnostic accuracy of liquid-based preparations in urine cytology by comparing the results of the conventional Cytospin preparation method for the same samples. A total of 236 cases subject to urine cytology were enrolled in this study from January 2005 to December 2005. All cases were subjected to cystoscopy and if a malignancy was suspected, a biopsy was performed. Urine cytology slides were made using the $ThinPrep^{(R)}$ preparation method and the conventional Cytospin and/or direct smear method from the individual samples. The results of urine cytology were compared with the final cystoscopic or histological diagnoses. We analyzed the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of both cytology preparation methods. A total of 236 slides made using the liquid based method were satisfactory for slide quality, whereas 5 slides (2.1%) prepared by conventional methods were unsatisfactory because of air-drying, a thick smear, or a bloody or inflammatory background. The $ThinPrep^{(R)}$ method showed 53.1% sensitivity, 92.6% specificity, a 92,6% positive predictive value, a 94.1% negative predictive value and 85,6% accuracy, while the conventional method showed 51% sensitivity, 98.4% specificity, a 92.6% positive predictive value, a 98.4% negative predictive value and 88,6% accuracy. Although the diagnostic values were equivalent between the use of the two methods, the quality of the cytology slides and the time consumed during the microscopic examination for a diagnosis were superior for the $ThinPrep^{(R)}$ method than for the conventional method. In conclusion, our limited studies have shown that the use of the liquid based preparation method is beneficial to improve the quality of slides and reduce the duration for a microscopic examination, but did not show better sensitivity, accuracy and predictive values.
췌관내 유두모양점액종양의 세침흡인 세포학적 소견 -1예 보고-
도인구,박재훈,김윤화,이주희,양문호,홍성화,박용구,Do, In-Gu,Park, Jae-Hoon,Kim, Youn-Wha,Lee, Ju-Hie,Yang, Moon-Ho,Hong, Sung-Wha,Park, Yong-Koo 대한세포병리학회 2003 대한세포병리학회지 Vol.14 No.2
Intraductal papillary mucinous tumor of the pancreas is characterized by intraductal papillary proliferation of mucin-producing epithelial cells with or without excessive mucin secretion. According to the degree of epithelial dysplasia, intraductal papillary mucinous tumor is classified into adenoma, borderline tumor, and carcinoma. We recently experienced a case of fine needle aspiration cytology of the intraductal papillary mucinous adenoma in a 69-year-old male. The fine needle aspiration cytology yielded flat sheets of columnar, mucin containing epithelial cells in the background of dense mucin containing degenerated cellular material and histiocytes.
$H\"{u}rthle$ 세포선종의 세침흡인 세포학적 소견 - 1예 보고 -
김봉희,강명숙,박재훈,김윤화,박용구,이주희,양문호,Kim, Bohng-Hee,Kang, Myoung-Suk,Park, Jae-Hoon,Kim, Youn-Wha,Park, Yong-Ku,Lee, Ju-Hie,Yang, Moon-Ho 대한세포병리학회 1995 대한세포병리학회지 Vol.6 No.2
The increased use of thyroid fine needle aspiration(FNA) has re-focused on $H\"{u}rthle$ cell lesions. The cytologic diagnosis of $H\"{u}rthle$ cell tumor is a challenge due to the presence of $H\"{u}rthle$ cells in non-neoplastic lesions and the inability to differentiate between benign and malignant $H\"{u}rthle$ cell tumor. We report a case of $H\"{u}rthle$ cell adenoma(HCA) un a 68-year old woman, with review of the cytopathologic findings. FNA revealed loosely cohesive or sheets of large oval to polygonal $H\"{u}rthle$ cells containing abundant granular cytoplasm. The hustopathologic examination confirmed the diagnosis of HCA with follicular growth pattern. Ultrastructurally, the cytoplasm was packed with variable sized mitochondria.