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      • 항문직장기형 재 수술로서 Pena술식

        이종원,김현영,최승은,정성은,이성철,박귀원,김우기,Lee, Jong-Won,Kim, Hyun-Young,Choi, Seung-Eun,Jung, Seung-Eun,Lee, Seong-Cheol,Park, Kwi-Won,Kim, Woo-Ki 대한소아외과학회 2002 소아외과 Vol.8 No.2

        The aim of this study was to evaluate the posterior sagittal anorectoplasty (PSARP) as a re-do operation in patients who failed initial repair of anorectal malformation. Nine patients (4 boys and 5 girls) who had previous failed surgery for anorectal malformation underwent secondary operations through posterior sagittal approach. The main reasons of surgery were constipation (n=3) and persistent anatomical derangement in spite of previous correction surgery (n=6). In addition to constipation, the former group (n=3) had various anatomical defects, and the latter group (n=6), of course, had constipation in some degrees. Patients ranged in age from 2 to 19 years (median 3 years) with only one over the age of 6 years. The primary procedures included PSARP (n=8) and anoplasty (n=1). The rectum was mobilized from surrounding structures through posterior sagittal approach and anatomical defects were corrected. The rectum underwent reconstruction, which involved relocation of the rectum and anus within the limits of the intact muscle complex. Patients underwent follow-up for periods ranging from 6 to 77 months (mean 37 months) after surgery. Anatomical corrections of all the defects were successfully fulfilled in 9 patients. All the patients were satisfied with the functional results after redo-PSARP compared with the preoperative defecatory function. This study suggests that (1) some of the patients with troublesome constipation may have anatomical defects, prominent or hidden, (2) surgeons should suspect the possibility of anatomical defect as the cause of incontinence and (3) preoperative thorough investigation to reveal the anatomical defects should be included in estimating patients with severe incontinence after previous surgery and planning the correction for failed previous surgery as well.

      • SCOPUSSCIEKCI등재

        교모세포종 U-251MG, U-373MG세포주의 Cytokines처리에 의한 세포내 ICAM-1 발현

        이종원,권정택,민병국,박승원,김영백,황성남,석종식,최덕영,Lee, Jong-Won,Kwon, Jung-Taek,Min, Byung-Kook,Park, Seung-Won,Kim, Young-Baeg,Hwang, Sung-Nam,Suk, Jong-Sik,Choi, Duck-Young 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.4

        Objective : Despite advances in the understanding of tumor biology and the tumor immunology, there has been no effective treatment. The Intercellular adhesion molecule-1(ICAM-1) has been shown to be important in interaction involving cells of the immune system and to be upregulated in a number of cell culture systems by cytokines, including immune interferon($IFN-{\gamma}$) and tumor necrosis $factor-{\alpha}$($TNF-{\alpha}$). ICAM-1 has been identified as one of the ligands for lymphocyte function-associated antigen-1(LFA-1). The effectiveness of various cytokines to ICAM-1 induction on cultured human glioblastoma cell lines and potential efficacy of immunotherapy were studied. Method : Human glioblastoma cell lines, U-251 MG, U-373 MG were trypsinized and suspended at $1{\times}10^5cells/ml$ and grown on 8 well chamber slide, the cells were incubated in 0.3ml medium alone or medium containing $IFN-{\gamma}$(1000U/ml) or $TNF-{\alpha}$(250U/ml) or $IFN-{\gamma}$ plus $TNF-{\alpha}$ for 6, 12, 24, 48 and 72 hours. The coverslip were then removed and stained with a 1/30 dilution of anti-ICAM-1 antibody. Result : Surface antigen expression of ICAM-1 was increased by incubating glioblastoma cell lines with $IFN-{\gamma}$ and $TNF-{\alpha}$. Combined effect of $IFN-{\gamma}$ and $TNF-{\alpha}$ has induced more ICAM-1 expression on glioblastoma cell lines. Upregulation of ICAM-1 expression in an established glioblastoma cell line was of greater magnitude and more rapid following incubation with $IFN-{\gamma}$ plus $TNF-{\alpha}$. Surface antigen expression of ICAM-1 was increased for up to 48 hours after cytokine treatment on both cell lines(p<0.05). There was no difference on both cell lines(p>0.05). Conclusion : The results of the present study indicate that ICAM-1 expression in glioblastoma cell lines, U-251 MG and U-373 MG, are induced and enhanced after treatment with $IFN-{\gamma}$ and $TNF-{\alpha}$. Combined effect of $IFN-{\alpha}$ and $TNF-{\gamma}$ is stronger and more rapid than $IFN-{\gamma}$ or $TNF-{\alpha}$ alone.

      • 한-일 간 3선(先) 논쟁에 관한 소고

        이종원(Lee, Jong-Won) 대한검도학회 2018 대한검도학회지 Vol.29 No.1

        우리나라에서 검도본을 수련할 때 ‘선선의 선’이라는 생소하고도 어려운 개념에 봉착하게 된다. 일본에서는 “검도본 1, 2, 3, 5본은 후도가 ‘선선의 선’으로 선도를 이긴다”라고 규정하고 있지만, 우리나라에서는 모든 본은 ‘후의 선’이라고 하는 명확한 규정은 없지만 대부분의 검도 인들이 그렇게 인식하고 있다. 이 두 경우는 외형상으로는 별 차이가 없어 보이지만, 이론상으로는 분명히 다르다. 이 연구에서는 이러한 한일 간 검도본의 ‘선’에 관한 인식차이를 규명하고자 한다. 이를 위하여 한국과 일본에서 제기된 네 가지의 대표적인 주장(즉, 미야모토 무사시, 이종림, 타카노 사사부로, 전일본검도연맹)을 중심으로 분석하였다. 앞 두 주장은 현상 또는 동작 기준으로 제기된 것이고, 뒤 두 주장은 동작과 정신을 한 이중기준으로 하고 있다. 스포츠적 측면에서 보면 동작중심의 앞 두 주장이 타당하며, ‘선선의 선’ 개념이 없는 이 둘은 사실상 같은 것이다. 이 두 주장이 스포츠과학적으로 옳다고 하더라도, 문제는 ‘선선의 선’ 개념을 내포한 일본검도형을 설명할 수는 없다는 것이다. 따라서 일본검도형과 스포츠검도가 공존할 수 있는 유일한 방법은 ‘선선의 선’을 인정하는 것이다. 그러나 우리나라에서는 일본 각 유파의 전통을 계승한 검도본 즉 일본검도형의 정신을 받아들이기 어려운 실정이다. 따라서 필자는 향후 이에 대한 실증적인 연구가 수행되어 세계검도인이 객관적으로 또한 과학적으로 받아들일 수 있는 합리적인 연구를 기대하면서 과도기적인 기간에 우리나라에서는 일본의 ‘선선의 선’을 보다 광의의 개념인 한국의 ‘선의 선’ 개념에 포함시킬 것을 제안한다. 그리고 1, 2, 3, 4, 5본은 후의 선으로 종전과 같이 두더라도 후도의 기세에 눌려(또는 압박을 받아) 선도가 할 수 없이 치고 들어오는 6, 7본은 후도가 ‘선선의 선(또는 선의 선)’으로 승리하는 것이 아닐까 생각한다. 이에 대한 논의 또한 제안한다. When practicing Kendo Kata in Korea, we are confronted with the strangely difficult concept of "sensen no sen". In Japan, "Kendo Kata 1, 2, 3, and 5 say that the shidachi wins uchidachi (the person who initiates the move in order to teach the principles of the techniques) by "sensen-no-sen". In Korea, however, the most Kendoists recognize that all Kendo Kata are ‘go-nosen’ even though there are no clear regulations. These two cases do not seem to be largely different in appearances, but they are clearly different in theory. In this paper, the author tries to clarify the differences of perception on "Kendo Kata’s sen" between "Korea" and "Japan". For this purpose, four main arguments are advocated in Korea and Japan (i.e., Miyamoto Musashi, Rhee Jong-rim, Takano Saaburo, and All Japan Kendo Federation) were analyzed in this paper. The former two arguments are based on the criteria of appearance and/or movement; on the other hand, the latter two arguments are based on the two criteria, the movement and the spirit. In terms of sports perspectives, the two arguments, which are focused on the motion, are valid, and the two without the concept of "sensen no sen" are virtually the same. Even if these two arguments are right in sports science, the problem is that we can not explain Nippon Kendo Kata that contains the concept of "sensen no sen’. Therefore, the only way for Nippon Kendo Kata and sports Kendo to coexist is to admit the concept of ‘sensen no sen’. In Korea, however, it is very difficult to accept the spirit of Nippon Kendo Kata, which succeeded the traditions of each Kendo style in Japan. Therefore, the author expects that the world"s Kendo people will be able to objectively and scientifically accept the rational research that has been carried out through empirical researches in the future. However, during the transitional period the author proposes to incorporate the concept of "sensen no sen’ in Japan into the concept of ‘sen no sen’ in Korea which is a broader concept. Furthermore the author argues that Kendo Kata 1, 2, 3, 4, 5 would be classified into the concept of ‘go no sen’, but the shidachi (the person in the position of learning the techniques) of Kendo Kata 6, 7 might win by ‘sensen no sen’ because the uchidachi is compelled to attack under the pressure of the shidachi. The author also suggests a discussion on this.

      • KCI등재

        올레핀 저장/회수 기술 응용을 위한 하이드로퀴논 크러스레이트의 분광학적 분석 연구

        이종원,도뗄 쁘라틱,강성필,Lee, Jong-Won,Pratik, Dotel,Kang, Seong-Pil 한국수소및신에너지학회 2013 한국수소 및 신에너지학회논문집 Vol.24 No.5

        Clathrate samples, using hydroquinone as a host and ethylene or propylene as a possible guest, were prepared and analyzed by means of spectroscopic measurements. Obtained results showed that ethylene can form clathrate compounds with hydroquinone at 4.0MPa and room temperature, while propylene cannot form clathrate compounds. Different formation behaviors of these two olefin compounds can be applied to a clathrate-based storage/recovery of ethylene in a selective way, and can provide useful information on the cavity size of the formed clathrate compounds.

      • KCI등재

        자갈축열층의 공기유동 및 축열성능

        이종원,Lee, Jong Won 한국농공학회 2014 한국농공학회논문집 Vol.56 No.3

        Fossil energy is needed for a whole year greenhouse cropping due to climate in South Korea. Because the most of the fossil energy resources is imported, it is necessary to develop technology to be able to reduce the energy cost in order to manage greenhouse profitably. The greenhouse commonly consume less amount of energy as compared to other industrial sectors. Replacement of fossil fuel with solar thermal storage, therefore, can be an economical as well as environmentally sustainable option for greenhouse heating. The fluid flow, heat storage and radiation characteristic of the gravel bed model were analyzed to provide basic data for design of the experimental solar heated greenhouse with underground thermal storage using gravel. The air flow velocity in the gravel storage bed was proven to be affected from the capacity of circulation fan and the circulation method and the positive pressure method was proven to be the best among the different air circulation methods. The initial air temperature of the thermal storage bed of 1.2 m $wide{\times}9$ m $long{\times}0.9$ m deep was $10^{\circ}C$. After the thermal storage bed is heated by air of the mean temperature $4^{\circ}C$ during 9 hours, the temperature has increased about $20.3^{\circ}C$ and the storage of heat was about 33,000 kcal. The important factors should be taken into consideration for design of the solar heated greenhouse with underground thermal storage using gravel are insulation of rock storage, amount of storing heat, inflow rate and direction of inlet and outlet duct.

      • KCI등재

        난소 절제술을 시행한 쥐와 정상 쥐에서 합성 골 재료의 이식 후 신생 골 생성 비교

        이종원,안진수,안재석,류재준,Lee, Jong-Won,Ahn, Jin-Su,Ahn, Jae-Seok,Ryu, Jae-Jun 대한치과보철학회 2008 대한치과보철학회지 Vol.46 No.4

        연구목적: 난소 절제술을 시행하여 골다공증을 재연한 쥐의 두개 결함부에 골 이식시 정상 쥐와 어떠한 골 재생 능력 차이를 보이는지 비교하고자 한다. 연구재료 및 방법: 20마리의 쥐를 2 그룹으로 각 10마리씩 나눈다. 그 중 10마리만 난소 절제술을 시행하고 7주 후 20마리 모두 두개골에 8 mm 직경의 임계 크기의 결함을 형성한 후 $OSTEON^{TM}$을 이식한다. 그 후 4주 후 모두 희생하여 조직학적 조각을 형성하여 방사선학적 및 조직형태학적 분석을 시행한다. 결과: Ovariectomy & $OSTEON^{TM}$군과 Non-Ovariectomy & $OSTEON^{TM}$군과의 신생골 형성 넓이의 효과 검증 결과, Ovariectomy & $OSTEON^{TM}$군은 평균 넓이는 19660.93 ${\pm}$ 17207.68 ${\mu}m$으로 Non-Ovariectomy & $OSTEON^{TM}$군의 69793.57 ${\pm}$ 33227.17 ${\mu}m$에 비해 적어진 것으로 나타났으며, 이러한 차이는 통계적으로도 유의한 것으로 나타났다 (t = -4.237, P < .01). 따라서 Ovariectomy & $OSTEON^{TM}$군의 new bone formation 넓이가 Non-Ovariectomy & $OSTEON^{TM}$군에 비해 작아진 것을 알 수 있다. Ovariectomy & $OSTEON^{TM}$ 군과 Non-Ovariectomy & $OSTEON^{TM}$ 군과의 알칼리 포스파타아제의 효과 검증 결과, Ovariectomy & $OSTEON^{TM}$군은 ALP는 평균 163.90 ${\pm}$ 61.44 IU/L으로 Non-Ovariectomy & $OSTEON^{TM}$군의 58.40 ${\pm}$ 18.30 IU/L에 비해 크게 높아진 것으로 나타났으며, 이러한 차이는 통계적으로도 유의한 것으로 나타났다 (t = 5.204, P < .001). 따라서 Ovariectomy & $OSTEON^{TM}$군의 ALP 수치가 Non-Ovariectomy & $OSTEON^{TM}$군 ALP 수치보다 높아진 것을 알 수 있다. 결론: 본 실험을 통해 골다공증이 유발되면 골 재생능력이 감소한다는 것을 결론지을 수 있다. Purpose of study: To compare on bone formation between ovariectomized rats and normal rats after graft of alloplastic bone material. Material and methods: Twenty female rats were used in this study. They were divided into two groups by each ten rats. One group was ovariectomized and grafted alloplastic bone material. Other group was non-ovariectomized and grafted alloplastic bone material. After a healing time of 4 weeks, the animals were sacrificed and decalcified preparations were routinely processed for histologic evaluations. Results: Ovariectomy group was significantly lesser bone formation compared with non-ovariectomy group. Conclusions: Ovariectomy acts as a negative factor in new bone formation.

      • KCI등재

        제한수신 기능 기반 T-DMB 시스템

        이종원,강인식,유대상,김종문,정회경,Lee, Jong-Won,Kang, In-Shik,Yu, Dae-Sang,Kim, Jong-Moon,Jung, Hoe-Kyung 한국정보통신학회 2016 한국정보통신학회논문지 Vol.20 No.5

        현재 지상파 이동 멀티미디어방송(T-DMB)은 국지적인 재난경보 방송을 실시하거나 다양한 방송을 시청할 수 있다. 그러나 전파 음영 지역에는 시설 투자의 한계로 인해 서비스가 제한되고 있는 실정이다. 또한 T-DMB 시청이 불가능한 모바일 디바이스들도 있기에 T-DMB는 제한된 지역과 모바일 디바이스들만 시청할 수 있는 방송이라는 문제점이 있다. 본 논문에서는 T-DMB의 문제점을 해결하기 위한 방법으로 T-DMB 방송을 수신하여 모바일 디바이스로 재전송해주는 시스템을 연구하였다. 이를 통해 T-DMB 수신이 불가능한 모바일 디바이스에서도 방송을 수신하여 시청할 수 있으며 제한수신 기능을 통한 단방향/양방향 인증 메커니즘을 제공하여 등록되어 있는 사용자에 한해서 방송을 시청할 수 있도록 시스템을 구성하였다. Current terrestrial Digital Multimedia Broadcasting (T-DMB) is conducting the emergency alert broadcast, or can view a variety of broadcasting. However, propagation shadow area is a situation where the service is limited due to limitations of facilities investment. In addition, there is the problem of T-DMB broadcasting is for viewing only a restricted area and a mobile device because the mobile is also T-DMB viewing device impossible. In this paper, it receives a T-DMB broadcasting as a way to solve the problems of the T-DMB system, which was studied the re transmission to the mobile device. Accordingly, by receiving the broadcast may be watched in the mobile device the T-DMB reception impossible. Also provides a one-way/two-way authentication mechanism using a conditional access function, and the system was configured so that the user can watch only the registered broadcasting.

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