대한약침학회지에 개재된 약침관련논문의 유형 분석

이종영,한영주,김진호,김영진,권기록,Lee, Jong-Young,Han, Young-Joo,Kim, Jin-Ho,Kim, Young-Jin,Kwon, Ki-Rok 대한약침학회 2006 Journal of pharmacopuncture Vol.9 No.3

Objectives : The focus of the analysis was laid on changes in research pertaining to pharmacopuncture in regards to time progression. Methods : Type analysis was done on pharmacopuncture related papers published in the Journal of Korean Institute of Pharmacopuncture from the inaugural issue to June 2006 issue. 196 papers are analyzed to the sort of type. Results : For type analysis of the type of studies, experiment papers outnumbered other types with 94 cases, followed by 67 for clinical trials, and 35 for literary studies. Type analysis on the type of illnesses listed in the Methods section, 31 papers concentrated on arthritis or HIVD of spine, 6 for Pharmacopuncture response in human, 5 for anti-cancer and immune disorders, etc. Conclusion : Since its inaugural issue in 1997 to August 2006 issue ranging 10 years, type analysis revealed that the number of journals pertaining to pharmacopuncture has risen steadily over the years and nearly half of papers published recently are dealing with pharmacopuncture. Pharmacopuncture is a treatment method based on the unique theory of Korean traditional medicine. Its superior efficacy is proven through numerous research works, and effort and academical approach on pharmacopuncture are expected to receive positive evaluation.

Development of A Device Constantly Stimulating Tuning Fork and Variability of Its Vibration Perception Time

이종영,홍대용,윤형렬,Lee, Jong-Young,Hong, Dae-Yong,Yoon, Hyeong-Ryeol The Korean Society for Preventive Medicine 1991 Journal of Preventive Medicine and Public Health Vol.24 No.1

진동감각의 이상을 검사하는데 음차를 이용한 진동 감지 시간을 측정하는 방법이 임상에서 널리 이용되고 있으나 이 방법은 동일 피검자에 대해서도 검사자에 따라 많은 차이가 있다. 이는 주로 음차에 가해지는 자극이 표준화되어 있지 못하고 경험에 의해 이루어 지고 있기 때문이다. 검사자간의 오차를 제거하기 위해 음차에 일정한 자극을 줄 수 있는 장치 (그림 1)를 전자석의 원리를 이용하여 개발하였다. 본 장비를 이용하여 28명의 건강한 의예과 남학생을 대상으로 그들의 오른손 집게손가락에서 측정된 진동 감지시간은 평균 12.44 초 였고, 9.47 에서 17.25 초 사이에 분포되었다. 그 변이 계수는 16.89% 였다. 30 분 후 재검사 한 결과와 첫 검사 사이의 상관계수는 0.957 이었다 (p<0.01). 본 검사법은 비침입적이며, 비염오적이고 간단하다. 이를 실시함에 있어 숙련이 요하지 않으며, 현상에서 쉽게 이루어질 수 있다. 검사 시간은 1 분 정도 밖에 걸리지 않으며 추적 조사도 가능하다. 또한 본 장비는 휴대에 간편하다. 진동감각의 장애가 말초신경 질환의 초기 징후일 수 있으며, 진동 지각 역치를 측정하는 방법들이 말초신경 질환의 조기발견에 이용되고 있음에 비추어 볼 때, 본 장치에 의해 진동 감지 시간을 측정하는 방법이 직업성 말초신경 질환의 조기발견을 위한 집단검진에 널리 사용될 수 있을 것으로 생각된다. The time honoured tuning fork at present widely available for examining vibration sensation is brought about the problem of great interobserver variation. To resolve t his problem, author developed a divice using electric magnet that stimulates constantly tuning fork. The perception time of vibration from tunung fork by this device was tested on the index finger of dominant hand of twenty eight subjects. It was 12.44 seconds on average and ranged from 9.47 to 17.25. Coefficient of variation of it was 16.89 percent. Correlation coefficient between test and retest after 30 minutes was 0.957(p<0.01). This device is portable. Test procedure in non-invasive, non-aversive and simple, can be performed within one minute, and does not require the skilled technician. It is felt that this device testing vibration perception time is suitable as screening tool for early detection of occupational peripheral neuropathy.

비인강암의 방사선 치료 성적

이종영,노준규,서창옥,이연구,홍원표,Lee Jong Young,Loh John J.K.,Suh Chang Ok,Lee Youn Goo,Hong Won Pyo 대한방사선종양학회 1988 Radiation Oncology Journal Vol.6 No.1

This study is the retrospective evaluation of ninety-six patients with biopsy-proven carcinoma of nasopharynx treated with radiotherapy at Yonsei University, College of Medicine, Radiation Oncology from January 1971 to December 1985. Patient's age ranged from 15 to 71 years with a median age of 49 years. Fifty-two point five percent of local control and $47.5\%$ of actuarial 5 year survival were achieved with radical radiotherapy. Five year survival rate for Stage I&II, III and IV were $75.0\%,\;74.6\%\;and\;41.4\%$, respectively. Distant metastasis rate was related with N stage $(N1\;12.5\%,\;N1\;0\%,\;N2\;23.5\%,\;N3\;32.1\%$and histologic type (lymphoepithelioma $41.7\%$, squamous cell carcinoma $6.5\%$) but not with T stage. Thirty-one of sixty-seven patient covered adequate radiation field received induction chemotherapy. However induction chemotherapy does not appear to improve over all survival.

혈맥(血脈)에 대한 문헌적 고찰

이종영,조병준,강대인,권기록,Lee, Jong-Young,Cho, Byung-Jun,Kang, Dae-In,Kwon, Ki-Rok 대한약침학회 2005 Journal of pharmacopuncture Vol.8 No.3

Objectives : This study focused on how the modem blood vessel is defined in Oriental medicine through literary investigation. Methods : Contents from 35 classical texts representing each era were analyzed for the expression of Hyeolmaek and affiliate information, as well as terms used for the current concept of blood vessel. Results : Following results were obtained through investigating literary information on Hyeolmaek. 1. In the Yellow Emperor's Classic, Hyeolmaek is associated with heart and widely used for physiological, pathological, diagnosis, and treatment purposes. 2. During the Song Dynasty, a term Cheonggeun (靑節). is used to describe the vein in the abdomen. 3. During the Ming Dynasty, terms such as Cheonggeun(靑節) and Cheongmaek(靑脈) were used. 4. The term Hyeolmaek was used inclusively for blood, blood vessels, arteries, veins, and as well as meridians.

Sweet Bee Venom 시술이 Rat의 호흡기계에 미치는 영향

이종영,권기록,Lee, Jong-Young,Kwon, Ki-Rok 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.3

Objectives: This study was performed to analyse the effects of Sweet Bee Venom(SBV-purified melittin supported by G&V Co., the major component of honey bee venom) on the respiratory system in rats. Methods: All experiments were conducted at Biotoxtech Company, a non-clinical studies authorized institution, under the regulations of Good Laboratory Practice(GLP). Male rats of 5 weeks old were chosen for this study and after confirming condition of rats was stable, SBV was administered in thigh muscle of rats in 0.175, 0.35 and 0.7 mg/kg dosage. And checked the effects of SBV on the respiratory system using the whole body plethysmography. And respiratory rate, tidal volume and minute volume of rats were checked after administered SBV (melittin). Results: 1. In the measurement of respiratory rate, there were not observed any significant differences compared with control group. 2. In the measurement of tidal volume, there was not observed any significant differences compared with control group. 3. In the measurement of minute volume, 0.35mg/kg dosage group showed significant differences compared with control group. But we estimated that this result was caused by individual differences. Conclusions: Above findings suggest that SBV seems to be safe treatment in the respiratory system of rats. And further studies on the subject should be conducted to yield more concrete evidences.

섬유공장(纖維工場)의 소음(騷音)이 근로자(勤勞者)들의 혈압(血壓)에 미치는 영향(影響)

이종영,Lee, Jong-Young 대한예방의학회 1984 예방의학회지 Vol.17 No.1

작업장소음(作業場騷音)에 의한 실제 근로자혈압변화(勤勞者血壓變化)의 양상을 파악(把握)하기 위하여 1983년 6월 8일부터 2주간 모(某) 섬유업체의 기숙사에서 생활(生活)하는 건강(健康)한 여성(女性) 근로자(勤勞者)들 중에서 기직공(機織工) 70명(名)과 가공공(加工工) 70명(名)을 대상(對象)으로 작업(作業) 전(前)과 30분(分) 후(後)의 혈압(血壓), 연령(年齡), 근무년수(勤務年數), 신장(身長), 체중(體重) 그리고 작업장소음(作業場騷音)에 대해 조사(調査) 분석(分析)하였다. 작업환경(作業環境)의 소음(騷音)은 가공부(加工部)에서 평균 80dB(A), 기직부(機織部)에서 평균99dB(A)였다. 일반적 특성에 있어 연령(年齡)은 가공공(加工工) 17.7세(歲), 기직공(機織工) 18.6세(歲)로 유의한 차(差)가 있으나(p<0.05), 신장, 체중 그리고 근무년수는 양 군(群)사이에 유의한 차(差)가 없었다. 수축기와 이완기의 평균혈압(平均血壓)은 각각 가공공(加工工)에서 108.9mmHg, 67.8mmHg, 기직공(機織工)에서 112.5mmHg, 71.6mmHg로 양 군(群)사이에 유의한 차(差)를 보였다(p<0.05). 작업(作業) 전(前)과 30분(分) 후(後)의 혈압변화(血壓變化)가 가공공(加工工)에서는 통계적으로 유의하지 않았으나, 기직공(機織工)에서는 수축기 3.2mmHg, 이완기 2.5mmHg의 유의한 증가(增加)를 보였다.(p<0.05) 혈압(血壓)에 대한 이원변량분석에서는 소음(騷音)에 의한 영향만이 유의하였고(p<0.05), 연령(年齡)과 이들의 상호작용(相互作用)에 의한 영향은 유의하지 않았다. 소음(騷音)이 근로자(勤勞者)들의 혈압증가(血壓增加)에 중요한 역할을 할 것이므로 소음작업(騷音作業) 근로자(勤勞者)들의 건강관리(健康管理)를 위해서는 작업장소음(作業場騷音)의 감소, 이보호구(耳保護具)의 사용(使用), 정기적인 혈압변화(血壓變化)의 관찰 그리고 고혈압(高血壓) 소질자(素質者)의 소음작업(騷音作業)의 제한 등의 대책이 필요하리라 생각된다. To assess the effect of noise on the blood pressure of workers, 70 weaving and 70 refining female workers in 15 to 24 years of ages were tested for the changes of blood pressure before and after exposure to the noise. The noise levels at work place were 99 dB (A) for weavers and 80 dB(A) for refiners. The mean age of refiners was 17,7 years and that of weavers was 18.6 years, and the difference in mean ages was statistically significant (p<0.05). The means of heights, weights and working durations were not significantly different between two groups. The mean systolic blood pressure of the weavers was 112.5mmHg before exposure to the noise and it was increased to 115.7mmHg after exposure to 99 dB(A) of noise for 30 minutes, and the mean diastolic blood pressure from 71.6mmHg to 74.1mmHg. These increments of blood pressure were statististically significant (p<0.05). The mean systolic blood pressure of the refiners was decreased from 108.9mmHg to 106.7mmHg after exposure to 80 dB(A) of noise for 30 minutes, and the mean diastolic blood pressure from 67.3mmHg to 67.1mmHg. These changes of blood pressure were not statistically significant. The mean systolic and diastolic blood pressure of the weavers before exposure to the noise were significantly higher than that of refiners (p<0.05). The difference of blood pressure between refiners and weavers was significantly associated with noises (p<0.05), and not ages and their interactions. The study results support the hypothesis that exposure to excessive noise increases the blood pressure of workers.

뇌하수체 선종의 방사선치료 후 발생한 교모세포종 - 증례 보고 -

이종영,박경란,김헌주,이종인,김명순,정순희,Lee Jong-Young,Park Kyung-Ran,Kim Hun-Joo,Lee Chong-In,Kim Myung-Soon,Jung Soon-Hee 대한방사선종양학회 1999 Radiation Oncology Journal Vol.17 No.4

A 39-year-old woman developed a glioblastoma about 7 years and 10 months after local radiotherapy (45 Gy) for pituitary adenoma. Clinical and histopathological details are presented, and previously reported cases of radiation-induced glioma are reviewed. 39세 여자환자에서 뇌하수체 선종으로 방사선치료(45 Gy)를 받은 지 7년 10개월 후에 교모세포종(glioblastoma)이 발생되었다. 본 저자들은 이에 대한 문헌고찰과 함께 증례 보고를 하고자 한다.

경락약침의 윤제(CF, JsD)에 의한 부작용 사례보고

이종영,강현민,임청산,권기록,Lee, Jong-Young,Kang, Hyun-Min,Lim, Chung-San,Kwon, Ki-Rok 대한약침학회 2007 Journal of pharmacopuncture Vol.10 No.3

Objectives This study aims to report inflammatory reactions of Pharmacopuncture lubricants (CF and JsD) when administered on GB21, GB20, and TE23 in clinical trials. Methods Follow-up studies were made on each patient's clinical observation and specific managemen. Results 1. Inflammation induced by pharmacopuncture lubricants were limited to local area of administration. 2. Intensity of inflammation was depended on the patient's condition. 3. Inflammation caused pain, skin flare, and discomfort on the patient. Inflammation subsided when dissipating technique was rendered with the conventional acupuncture needle. Conclusions It appears that prolonged usage of pharmacopuncture lubricant on the specific point can induce inflammation, thus using alternative pharmacopuncture is recommended.

혈중(血中) 셀레늄 농도(濃度)와 위장질환(胃臟疾患)의 관련성(關聯性)

이종영,김두희,박승국,Lee, Jong-Young,Kim, Doo-Hie,Park, Seoung-Kook 대한예방의학회 1988 예방의학회지 Vol.21 No.1

혈중 셀레늄 농도와 위장질환과의 관련성을 밝히기 위해, 1986년 7월에서 9월 사이에 대구시내 2개 대학병원 외래를 방문하여 위내시경검사를 받은 사람들 중에서 간장질환, 신장질환, 식도정맥류 및 십이지장질환을 제외한 175명을 대상으로 일반적 특성을 조사하고, 정맥혈 5ml를 채취하여 flameless atomic absorption spectrophotometry를 이용하여 혈중 셀레늄농도를 측정하였다. 평균 혈중 셀레늄농도는 위염($155.5{\pm}14.0{\mu}g/{\ell}$), 위궤양($154.8{\pm}29.3{\mu}g/{\ell}$) 그리고 위암($133.0{\pm}8.4{\mu}g/{\ell}$)으로 모두가 위내시경 음성군($173.3{\pm}33.6{\mu}g/{\ell}$) 보다 통계적으로 유의하게 낮았다(p<0.05). 남성에서도 위염, 위궤양 그리고 위암 모두는 통계적으로 유의하게 낮았지만(p<05), 여성에서는 위염과 위암이 음성군 보다 유의하게 낮았고(p<0.05), 위궤양은 평균 혈중 셀레늄농도가 $177.7{\mu}g/{\ell}$로 음성군($169.7{\mu}g/{\ell}$)보다 높았지만 통계적으로 유의하지는 않았다. McGee의 LOGRESS Program에 의한 logistic분석에 있어 혈중 셀레늄농도의 계수는 위염과 -0.0436(p<0.05 ; odds ratio 0.957), 위궤양과 -0.0197(p=0.17 ; 0.981), 위암과 -0.4876(p<0.05 : 0.614) 그리고 위장질환 전체와는 -0.0411(p<0.05 ; 0.960)이었다. 이상의 성적은 비록 그 검사예수가 적지만 위염, 위궤양 특히 위암에 있어서 혈중 셀레늄농도가 위내시경 정상 소견을 보인 예에 비하여 낮았다는 사실은 혈중 셀레늄과 몇가지 위장질환과는 어떠한 관련성을 시사하는 자료가 된다고 하겠으며 추후 많은 추적검사가 필요할 것으로 보인다. (본 논문의 자료 수집을 위해 협조해 주신 경북의대와 계명의대 내과학교실 및 임상병리학교실 여러 선생님께 깊은 감사를 드립니다. 또한 셀레늄 분석과 원고 교정을 도와준 장봉기 선생과 자료의 통계처리를 도와준 천병렬선생께도 뜨거운 감사를 드립니다.) To reveal the association between blood selenium level and the gastric diseases, 180 persons received the gastrofiberscopic examination at the outpatients department of the two university hospitals from July to September 1987, after the exclusion of the persons having the esophageal varix, were randomly selected. Their general characteristics such as age, sex and educational level and so on, were inverstigated. Five mi venous blood was collected from each subjects and stored at $0^{\circ}C$ in heparinized vaccum tube. The blood selenium level was measured by the flameless atomic absorption spectrophotometry. In the procedure of data analysis, five subjects having benign tumor and anomaly of the stomach, were also excluded. The mean blood selenium levels of the $155.5{\mu}g/{\ell}$ among gastritis cases, the $154.8{\mu}g/{\ell}$ gastric ulcer and the $133.0{\mu}g/{\ell}$ gastric malignancy were significantly lower(p<0.05) than that of the $173.3{\mu}g/{\ell}$ among normal controls. In men the mean blood selenium levels .among gastritis, gastric ulcer and gastric malignancy cases were significantly lower(p<0.05) than that among normal controls. In females, the mean blood selenium levels among gastritis and gastric maligancy cases were significantly lower(p<0.05) than that among normal controls($169.7{\mu}g/{\ell}$), but that among gastric ulcer cases($177.7{\mu}g/{\ell}$) was not significantly higher. In the logistic analysis, coefficient of the blood selenium level was -0.0436(p<0.05 : odds ratio 0.957) for gastritis, -0.0197(p=0.17 : 0.981) for gastric ulcer, -0.4876(p<0.05 : 0.614) for gastric malignancy and -0.0411(p<0.05 ; 0.960) for gastric diseases including the gastritis, the gastric ulcer and the gastric malignancy. These data support the hypothesis that the gastric diseases are to be associated with the low selenium level but, for the gastric ulcer, the further research is recommended.

국내 연약지반의 심도별 과압밀비 산정에 관한 사례연구

이종영,한중근,Lee, Jong-Young,Han, Jung-Geun 한국지반신소재학회 2021 한국지반신소재학회 논문집 Vol.20 No.4

본 연구에서는 국내 연약점토지반을 대상으로 현장에서 불교란 상태로 채취된 흙을 이용해 실내 물리실험 및 역학시험을 실시하여 OCR을 산정하였으며, 실험 결과를 이용해 기존의 경험식과 심도별로 OCR을 예측하였다. 액성지수와 NAVFAC의 경험식을 실제 측정값과 비교·검토한 결과 액성지수를 이용한 방법이 지반의 개략적인 OCR을 추정하기에 적절한 것으로 나타났으나 지하수위 상부 지반의 경우에는 건조로 인한 영향을 고려하지 못한 것으로 나타났다. 따라서 지하수위 상부지반을 포함한 각 지역별 심도-OCR간의 상관관계식을 제안하였으며, 제안된 식을 인접지역의 OCR 예측에 적용한 결과 점토(CL, CH)로 구성된 지역에서의 예측값은 실측값과 상당부분 일치하는 경향을 보였다. 그러나 실트(ML)로 구성된 지역에서는 예측값이 실제값과 불일치한 결과를 보여 흙의 공학적 특성보다는 퇴적 및 구성 특성이 OCR예측에 중요한 영향인자임을 확인할 수 있었다. In this study, the overconsolidation ratio (OCR) of soft clay soil was calculated by conducting an indoor physical experiment and a dynamics test using undisturbed soil samples from a soft clay soil field in South Korea. The OCR by depth was predicted by comparing the experimental results with the existing empirical equations. Methods using the liquidity index and the existing empirical equation by the Naval Facilities Engineering Systems Command (NAVFAC) were examined, and the results were compared with the actual measured values. The method using the liquidity index was found to be suitable for estimating the rough OCR of the ground. However, the effect of drying was not considered for the ground above the groundwater level. Therefore, an equation for the correlation equation between the depth and OCR of each region, including the ground above the groundwater level, was proposed. The proposed equation was applied to the OCR prediction of the adjacent area. The predicted values in the area composed of clay (CL, CH) were found to be in good agreement with the actual values. In the region composed of silt (ML), however, the predicted values were not consistent with the actual values. This suggests that the sedimentation and compositional characteristics, rather than the engineering characteristics of the soil, are important factors that affect the OCR prediction.