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함양산양삼과 열매 복합물의 항산화 및 항염증 효능에 대한 연구
이종상,주인환,박종민,김동희,Jong-Sang Lee,In-Hwan Joo,Jong-Min Park,Dong-Hee Kim 대한동의생리학회·한의병리학회 2023 동의생리병리학회지 Vol.37 No.3
The purpose of this study is to examine the antioxidant effect of hamyang wild-simulated ginseng and ginseng berry complex(HGC) and to investigate the mechanism of anti-inflammatory effect on macrophage cell line (RAW264.7 cells). For antioxidant activity of HGC was measured by total polyphenol contents were estimated with folin-ciocalteu method, and total flavonoid contents were estimated with aluminum chloride methods. And, assessed with 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity assay. MTT assay was performed to determine the effect of HGC on cell viability in RAW264.7 cells. In addition, anti-inflammatory effect of HGC was investigated in RAW264.7 cells. RAW 264.7 cells, in which an inflammatory response was induced by lipopolysarccharide (LPS), were treated with HGC, and nitric oxide production was measured by griess assay. And protein expression level of inflammatory cytokine and phosphorylation of MAPK signaling pathways were confirmed by western blot analysis. Total polyphenols and flavonoids contents in HGC were quantified, and increased DPPH and ABTS radical scavenging activity in a concentration-dependent manner was confirmed. In addition, HGC was significantly inhibited nitric oxide (NO) production and inflammatory cytokine (iNOS, IL-1β, IL-6, and TNF-α) expression in LPS-stimulated RAW264.7 cells. Also, HGC was significantly inhibited the phosphorylation of MAPK signaling pathways. These results suggest that HGC can be used as effective herbal medicine extract for antioxidant and anti-inflammatory effect. As a result, it is thought that HCG can be used as a functional material effective for antioxidant and anti-inflammatory effects. And it will be possible to promote industrialization using hamyang wild-simulated ginseng and ginseng berry, and to increase high-value-added.
이종상(Jong-Sang Lee),장갑만(Kap-Man Jang),이윤형(Yoon Hyoung Lee),임상식(Sang-Sik Yim),이진한(Jin-Han Lee) 한국가스학회 2014 한국가스학회지 Vol.18 No.6
본 연구에서는 STS304로 만든 소형프로판용기의 내압증가에 따른 형상변화를 분석하였다. 소형 프로판용기는 내압이 증가하면 하부 경판이 아래쪽으로 볼록하게 형상이 변한다. 이러한 형상변화에 따른 소형 프로판용기의 내압의 변화를 분석하고자 기존의 내압시험과는 다른 방법인 수조식 내압 시험방법을 이용하였다. 수조식 내압시험 방법은 가압에 따른 용기의 체적변화량을 실시간으로 측정해 용기의 내압과 체적과의 관계를 분석 가능하다. 분석결과 하부 경판부의 형상변화에 따른 용기변형구간이 존재하고 용기의 하부 경판부의 변형이 시작되면 가압에 따른 부피증가량이 비례하지 않고 더 많이 증가되어 내압이 감소하는 경향을 나타낸다는 것을 확인하였다. 본 연구의 결과는 소형 프로판용기 뿐만 아니라 다양한 압력용기의 안전성 향상에 기여할 것을 기대한다. In this study, it is analyzed that a change in the shape of small propane containers made of STS304 when increasing of internal pressure. When internal pressure of a small propane container increased, bottom of end plate is convexly changed. This test is applied to a water bath pressure test to analyze the characteristics of the container. Water bath is able to analyze relationship between internal pressure and volume. In result, shape change section is confirmed because bottom of end plate is convexly changed. In addition, this section tend to decrease internal pressure because a volume increment increase out of proportion to pressure. The results of this study are expected to contribute to improving the safety of the pressure vessel, as well as various small propane container.
李鍾祥(LEE Jong-sang),李源福(토론자) 고구려발해학회 2003 고구려발해연구 Vol.16 No.-
The major themes discussed in this paper is the technical significance of Koguryo murals and Koguryo murals in the history of Korean paintings. The emphasis was given on revealing the fact that Koguro murals were produced by a creative technique different from that of other countries. As of a technique of wall paintings, in the history of Europe art, a dry fresco technique developed into an oil painting technique using oil solvent with high viscosity. Secco-Fresco coexists with an oil painting as a watercolor painting technique in the west. In the history of Asian art, dry fresco technique developed into color paintings of Northern School. Buon-Fresco evolved into an ink painting of Southern School. However, the distinguished characteristics of Koguryo murals has its secret in that it achieves a plastered surface without using adhesives on wall painting on the natural wall and wall painting with a dry technique. This type of technique in Koguryo fresco sometimes evolved as using completely different materials and techniques from those of Chinese wall paintings according to her regional feature. It also became the basis of Korean art in later periods, and we can see that its basic frame still continues to the present time.