실시간 신호제어를 위한 신경망 적용 지체최소화 주기길이 설계모형 개발

이정윤,김진태,장명순,Lee, Jeong-Yun,Kim, Jin-Tae,Jang, Myeong-Sun 한국도로교통협회 2005 도로교통 Vol.99 No.-

질량감도 해석에 의한 2차원 연속계의 진동특성에 관한 연구

이정윤,박호,오재응,Lee, Jung-Yoon,Park, Ho,Oh, Jae-Eung 대한기계학회 1990 대한기계학회논문집 Vol.14 No.2

Techniques which are able to predict and control dynamic characteristics, not affecting the vibrational characteristics on the modification of structural design, are being studied. As one of these techniques, experimental modal analysis is widely applied by many researchers. In this study, modal analysis is performed using transfer matrix method by a macro computer. The developed program would estimate the structural modal parameters precisely, and the validity of this program is certified by comparing with the experimental results of .GAMMA A. structure. Estimated modal parameters(natural frequency, vibrational mode, equivalent mass, etc.) are in accord with the experimental results. Also, the optimal location of the additive mass is determined by the evaluation of the vibrational mode and the equivalent mass. The relation between the additive mass and the equivalent mass is specified, and we come to know that the ratio of equivalent mass to additive mass alter linearly within the range of 20%.

Short-term Effect of Botulinum Toxin Injection on the Surface EMG of Masticatory Muscles and Jaw Function

이정윤,박희경,정진우,Lee, Jeong-Yun,Park, Hee-Kyung,Chung, Jin-Woo Korean Academy of Orofacial Pain and Oral Medicine 2006 Journal of Oral Medicine and Pain Vol.31 No.1

Botulinum toxin injection has been used in the masticatory muscle area as an effective treatment method of various movement disorders and facial contouring, but its effects on jaw function have not been evaluated. The aims of this study were to evaluate the effects of botulinum toxin type A injection into the masseter muscle on the EMG activities of masseter and anterior temporal muscles, and the limitation of jaw function. Fourteen healthy subjects were recruited. Five subjects were injected with 80 units of botulinum toxin type A(Dysport, Ipsen, Wrexham, UK) into each side of masseter muscle, and nine subjects were injected with saline into the same site as the botulinum toxin group. The surface EMG activities at maximum voluntary contraction of masseter and anterior temporal muscles were recorded before, 1 week, 2 weeks, and 3 weeks after injection. Presence of jaw functional limitations in each subject was investigated using Korean version of Jaw Functional Limitation Scale(JFLS) questionnaire. The masseter muscle EMG was gradually decreased in the botulinum toxin group comparing with that of the control group(p<0.001), but the anterior temporal muscle EMG did not show significant changes. There was significant increases in the mastication (p<0.01), and global jaw limitation(p<0.05) subscales of JFLS at 1 week after injection, but no significant changes in the other subscales including opening, and verbal and emotional expression during the recording periods. Our results suggest that botulinum toxin injection into masseter muscle can affect modest limitation in mastication function at 1 week after injection but recovered to the baseline until 3 weeks after injection. The EMG activity of masseter muscle had been gradually decreased until 3 weeks after botulinum toxin injection but the anterior temporal muscle did not show any significant changes.

도로표지 설계에 사용성 평가기법 도입방안 검토 연구

이정윤,김주영,Lee, Jeong-Yun,Kim, Ju-Yeong 한국도로교통협회 2004 도로교통 Vol.96 No.-

HR-WPAN에서 채널 상태에 따른 우회 채널 할당

이정윤,김성수,김장형,송왕철,Lee Jung-Yun,Kim Sung-Su,Kim Jang-Hyung,Song Wang-Cheol 한국정보통신학회 2006 한국정보통신학회논문지 Vol.10 No.5

High-rate WPAN 은 CAT의 Time Slot 할당 스케줄링 방법을 정의 하고 있지 않다. 이에 CAT의 Time Slot 할당 스케줄링 방법 에 관한 많은 연구가 진행 중이다. 하지만 지금까지의 연구들은 Air Interface의 에러 요소의 미적용이나 특정 DEV의 기아 현상 등의 단점 등을 내포하고 있다. 이에 본 논문에서는 채널의 상태에 따른 우회 경로를 제공하여 채널 타임 할당 스케줄링 방법의 단점을 극복하는 알고리즘을 제안한다. Wireless Personal Area Networks(WAPANs) are designed for short-range ad hoc connectivity among portable devices. They have gained much attention in the industry recently. One of them, High-rate WPAN, is designed to support multimedia traffic that requires high data rates. But, High-rate WPAN standards don't specify the time slot assignment scheduling method of CAT(Channel Time Allocation). So, there has been many studies regarding time slot assignment scheduling of CAT. However, present studies involve demerits about not applying various types of errors in air interlace or having a starvation of a specific DEV(data device). In this paper, we propose algorithms about supplying the intermediate channel assignment in order to avoid these demerits. This method will help other methods that use time slot assignment scheduling of CTA.

"적게 먹지 않아도 된다"에 속지 말라

이정윤,Lee, Jeong-Yun 한국과학기술단체총연합회 2003 과학과 기술 Vol.36 No.7

제77회 REAAA Council Meeting 및 제3회 HORA Meeting 참관기

이정윤,Lee, Jeong-Yun 한국도로교통협회 2004 도로교통 Vol.98 No.-

설계파라미터 변경에 따른 구조물의 동특성 변화 해석

이정윤,Lee, Jeong-Yun 대한기계학회 2002 大韓機械學會論文集A Vol.26 No.4

This study predicts the modified structural eigenvectors and eigenvalues due to the change in the mass and stiffness of a structure by iterative calculation of the sensitivity coefficient using the original dynamic characteristics. The method is applied to examples of a cantilever and 3 degree of freedom lumped mass model by modifing the mass and stillness. The predicted dynamic characteristics are in good agreement with these from the structural reanalysis using the modified mass and stiffness.

적극적 스트레스 대처매개 중재가 임상실습 스트레스와 만족도에 미치는 영향

이정윤,황혜경,Lee, Jeong-Yun,Hwang, Hye-Kyung 한국임상보건과학회 2019 한국임상보건과학회지 Vol.7 No.2

Purpose: This study aimed to determine the mediating effects of aggressive stress response on the association between clinical practice stress and clinical practice satisfaction in ophthalmic optics majors and provide basic data that could help form opticians' professionalism and make clinical practice more effective. Methods: This study was conducted in 236 sophomores and juniors in Daegu and North Gyeongsang Province who had finished clinical practice. Hierarchical regression analysis and mediating effect testing were performed to determine the associations among clinical practice stress, clinical practice satisfaction, and aggressive stress response and determine the mediating effects of aggressive stress response on the association between clinical practice stress and clinical practice satisfaction. Results: Clinical practice stress was significantly negatively correlated with clinical practice satisfaction and aggressive stress response (p<0.01), and aggressive stress response was significantly positively correlated with clinical practice satisfaction (p<0.01). The association between clinical practice stress and clinical practice satisfaction was more likely to be explained by the addition of clinical practice stress than by being aggressive stress response controlled, which statistically significantly met the criteria for mediating effects (p<0.001). Conclusions: It is necessary to pay more attention to program development and teaching methods within the department of ophthalmic optics so that ophthalmic optics majors can utilize aggressive stress response to overcome clinical practice stress effectively and improve clinical practice satisfaction.

Biomarker-guided targeted therapy in platinum-resistant ovarian cancer (AMBITION; KGOG 3045): a multicentre, open-label, five-arm, uncontrolled, umbrella trial

이정윤,김병기,Jae Weon Kim,Jung Bok Lee,Eunhyang Park,Je-Gun Joung,김성훈,Chel Hun Choi,Hee Seung Kim 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.4

Objective: Management of heavily pre-treated platinum-resistant ovarian cancer remains a therapeutic challenge. Outcomes are poor with non-platinum, single-agent chemotherapy (CT); however, molecularly targeted anticancer therapies provide new options. Methods: This open-label, investigator-initiated, phase 2 umbrella trial (NCT03699449) enrolled patients with platinum-resistant ovarian cancer (at least 2 prior lines of CTand Eastern Cooperative Oncology Group 0/1) to receive combination therapy based on homologous recombination deficiency (HRD) and programmed death ligand 1 (PD-L1) status determined by archival tumour sample assessment. HRD-positive patients were randomised to either olaparib 200mg bid tablet + cediranib 30mg qd (arm 1) or olaparib 300mg bid tablet + durvalumab 1,500mg q4w (arm 2). HRD-negative patients were allocated to either durvalumab 1,500 mg q4w + pegylated liposomal doxorubicin (PLD) or topotecan or weekly paclitaxel (6 cycles; arm 3, those with PD-L1 expression) or durvalumab 1,500 mg q4w + tremelimumab 75mg q4w (4 doses) + PLD or topotecan or weekly paclitaxel (4 cycles; arm 4, those without PD-L1 expression). Arm 5 (durvalumab 1,500 mg q4w + tremelimumab 300mg [1 dose] + weekly paclitaxel [60 mg/m2 D1,8,15 q4w for 4 cycles] was initiated after arm 4 completed. The primary endpoint was objective response rate (ORR; Response Evaluation Criteria in Solid Tumours 1.1). Results: Between Dec 2018 and Oct 2020, 70 patients (median 57 years; median 3 prior treatment lines [range 2–10]) were treated (n=16, 14, 5, 18, and 17, respectively). Overall ORR was 37.1% (26/70, 95% confidence interval=25.9, 49.5); 2 achieved complete response. ORR was 50%, 42.9%, 20%, 33.3%, and 29.4%, respectively. Grade 3/4 treatment-related adverse events (TRAEs) were reported in 37.5%, 35.7%, 20%, 66.7%, and 35.3% of patients, respectively. No TRAEs leading to treatment discontinuation and no grade 5 TRAEs were observed. Conclusion: This study, the first biomarker-driven umbrella trial in platinum-resistant recurrent ovarian cancer, suggests clinical utility with biomarker-driven targeted therapy. All treatment combinations were manageable, and without unexpected toxicities.