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- 저자 : 이응배 ( Lee Eung Bae ) (검색결과 5 건)
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신무철 ( Moo Cheol Shin ),이승준 ( Seung Jun Lee ),윤석진 ( Seok Jin Yoon ),김은진 ( Eun Jin Kim ),이응배 ( Eung Bae Lee ),차승익 ( Seung Ick Cha ),박재용 ( Jae Yong Park ),정태훈 ( Tae Hoon Jung ),김창호 ( Chang Ho Kim ) 대한결핵 및 호흡기학회 2006 Tuberculosis and Respiratory Diseases Vol.60 No.5
배경 : 결핵성 농흉은 단순 결핵성 흉막염보다 빈도는 낮으나 공동이나 중증 폐결핵과 흔히 동반되고, 배농과 함께 장기적인 치료를 요하는 흉강의 만성적 활동성 감염질환이다. 국내에서도 이러한 결핵성 농흉 환자가 드물지 않게 발생하고 있으나 지금까지 이에 대한 연구가 거의 없었다. 방법 : 1991년 1월부터 2004년 4월까지 경북대 학교병원에서 결핵성 농흉으로 진단된 17예의 환자를 대상으로 후향적 조사를 시행하였다. 결과 : 대상환자 17예 중 12예(17%)에서 폐결핵 치료 과거력(6예) 혹은 현재 치료중인 폐결핵(6예)과 관련이 있었으며, 가장 흔한 증상으로는 객담이 동반된 기침, 발열, 호흡곤란의 순이었다. 중증 폐결핵 병변이 53%, 공동성 병변이 12%, 농기흉이 41%에서 관찰되었다. 흉막액 분석이 가능하였던 8예 모두에서 다형핵백혈구 우세의 삼출액이었으며, 세균성 감염이 47%에서 동반되어 있었다. 객담 항산균 도말검사는 71%, 객담 결핵균 배양검사는 64%에서 양성을 보였으며, 흉막액의 항산균 도말검사는 33%, 흉막액 결핵균 배양검사는 36%에서 양성을 보였다. 추적 관찰된 16예 중에서 외과적 치료를 시행한 3예를 포함한 12예(75%)에서 성공적으로 치료되었고, 2예(12%)는 사망하였다. 결론 : 결핵성 농흉은 농기흉을 동반한 중증의 폐결핵과 흔히 동반되고, 흉막액의 백혈구 감별계산에서 다형핵백혈구 우세를 보이며, 흉막강의 세균성 감염이 흔히 동반되었다. 따라서 심한 폐병변과 동반되어 완전한 농이나 다형백혈구 우세 소견을 보이는 화농성 흉막액 환자에서 결핵성 농흉을 감별진단에 반드시 고려하여 이에 대한 적극적인 조사와 치료가 필요할 것으로 생각된다. Background : In contrast to tuberculous pleurisy, tuberculous empyema is a chronic active infectious disease of the pleural cavity that is frequently accompanied by cavitary or advanced pulmonary lesions. The condition requires long-term anti-tuberculous medication with external drainage. The clinical features and treatment outcome of tuberculous empyema are unclear despite the high prevalence of tuberculosis in Korea. Methods : From January 1991 through April 2004, 17 patients diagnosed with tuberculous empyema in Kyungpook National University Hospital were enrolled in this study. Their medical records and chest radiographs were reviewed. Results : Twelve patients(71%) had a history of tuberculosis and six of the 12 patients were under current anti-tuberculous medication. Productive cough, fever, and dyspnea were the main complaints. There was no predominance between the right and left lungs. Nine patients(53%) had far-advanced pulmonary tuberculosis, two(12%) had a cavitary lesion, and seven(41%) had a pyopneumothorax on the chest radiograph. All eight cases in whom the data of pleural fluid WBC differential count was available showed polymorphonuclear leukocyte predominance. Eight patients(47%) had other bacterial infections as well. The overall rates of a positive sputum AFB smear and culture for M. tuberculosis were 71% and 64%, respectively. The positive AFB smear and culture rates for M. tuberculosis from the pleural fluid were 33% and 36%, respectively. Twelve of the 16 patients(75%) were treated successfully. Three underwent additional surgical intervention. Two patients (12%) died during treatment. Conclusion : Tuberculous empyema is frequently accompanied by advanced pulmonary lesions, and polymorphonuclear leukocytes are predominant in the pleural fluid. Other accompanying bacterial infections in the pleural cavity are also common in tuberculous empyema patients. Therefore, tuberculous empyema should be considered in differential diagnosis of patients with polymorphonuclear leukocyte-predominant pleural effusion. In addition, more active effort will be needed to achieve a bacteriological diagnosis in the pleural fluid. (Tuberc Respir Dis 2006; 60: 516-522)
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한국인에서 Myeloperoxidase (MPO) 유전자의 -463G>A 다형성과 원발성 폐암의 위험도
박재형 ( Jae Hyoung Park ),박정민 ( Jung Min Park ),김은진 ( Eun Jin Kim ),윤석진 ( Suk Jin Yun ),이승준 ( Sung Jun Lee ),차승익 ( Sung Ick Cha ),이응배 ( Eung Bae Lee ),김창호 ( Chang Ho Kim ),감신 ( Sin Kam ),김동선 ( Dong Sun 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.59 No.2
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최창훈,이신원,정귀화,박시형,이순희,김정국,하승우,김보완,이상철,이응배,박태인 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.2
Paraganglioma is an extraadrenal pheochromocytoma originating from chromaffin cells distributed in the sympathetic nervous systems. Functioning extraadrenal paragangliomas represent more than 10% of all pheochromocytomas, and seems to be highly malignant tumor in comparison to intraadrenal pheochromocytomas. Recently, we experienced a case of a paraganglioma in the posterior mediastinum. A 32-year-old woman was admitted to hospital due to dyspnea on exertion, and intractable hypertension. A chest X-ray showed a well-defined mass density on the right cardiac border, and biochemical studies showed characteristic findings of pheochromocytoma. A solitary pheochromocytoma was located in the posterior mediastinum using 131I-MIBG scintigraphy. The clinical manifestations, including hypertension and dyspnea were improved after operation
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흉강경하 흉부교감신경절단에 따른 심박수 변이도의 스펙트럼 분석
박성식,김석희,김시오,홍정길,문철원,이응배 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.42 No.2
Background : In general, we know that a thoracic sympathicotomy may have influence an cardiac autonomic nervous activity to change vital signs. The purpose of this study was to analyse preoperative and postoperative heart rate variability to evaluate the influence of a sympathicotomy on cardiac autonomic activity. Methods : We studied 14 healthy patients, ASA physical status Ⅰ and Ⅱ, undergoing an endoscopic thoracic sympathicotomy. A laryngeal airway mask was performed on all patients for tracheal intubation. Intravenous anesthesia was induced by administration of propofol 10 ㎎/㎏, and fentanyl 2 ㎍/㎏ and was maintained with propofol 10 ㎍/㎏/hr and N_2O-O_2 (2 L/min-2 L/min). An electrocardiogram was checked in the supine position with Biopac Student Lab. at an hour before anesthetic induction, after a left and right sympathicotomy and at 3-4 hours after emergence. A spike 2 version 3.0 was used for analyzing heart rate variability and a Fast Fourier Transform was used to yield a power spectrum. Frequency bands were divides to low frequency (0.02-0.09 ㎐) components. Results : There were no significant changes of heart rate, high frequency component, low frequency component and ratio of low to high frequency component. Conclusions : Influence of a thoracic sympathicotomy on cardiac autonomic activity was less in the supine position at rest. However, we think that the response of the cardiac autonomic activity to sympathetic stimulation like position change and exercise after a sympathicotomy may yield different results and studies about this must be done. (Korean J Anesthesiol 2002; 42: 177~182)
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