체외수정시술 환자의 과배란유도시 저용량 아스피린 투여의 효용성에 관한 연구

이은실,이상훈,Lee, Eun-Sil,Lee, Sang-Hoon 대한생식의학회 2001 Clinical and Experimental Reproductive Medicine Vol.28 No.3

Objective : To evaluate the efficacy of low-dose aspirin on IVF outcome and endometrium in patients undergoing IVF-ET. Materials and Methods : From February, 2001 to Jun, 2001, 60 infertile patients were randomly divided into study group (28 cycles) and control group (32 cycles). The study group received a daily oral dose of 25 mg of aspirin for at least 2 weeks from first visiting day. Controlled ovarian hyperstimulation was initiated in all patients with the GnRH agonist starting in the midluteal phase of the previous cycle. Results: There were no significant differences in age of the patients, basal serum E2, LH, FSH level and endometrial thickness among two groups. There were no statistically significant differences between the study group and the control group respectively in dosage ($26.5{\pm}4.8$ vs $26.2{\pm}5.3$ amples) and duration ($10.4{\pm}4.2$ vs $9.8{\pm}5.3$ days) of gonadotropin administration, serum E2 level on the hCG administration day ($1823{\pm}342$ vs $1854{\pm}543$), LH ($14.5{\pm}2.7$ vs $14.8{\pm}3.1$), FSH ($16.7{\pm}3.4$ vs $18.3{\pm}4.7$), the number of follicles > 15 mm ($13.2{\pm}6.3$ vs $12.8{\pm}5.9$), the number of oocytes retrieved ($9.2{\pm}2.4$ vs $8.4{\pm}1.7$), the number of embryos transferred ($4.7{\pm}2.0$ vs $4.7{\pm}2.0$), fertilization rate (68.4% vs 64.5%), implantation rate (21.3% vs 17.6%), and clinical pregnancy rate (28.4% vs 26.2%). The endometrial thickness and the percentage of endometrial trilaminar pattern on hCG day were significantly higher in study group than control group ($12.9{\pm}3.7mm$ vs $10.4{\pm}2.8mm$, 78.3% vs 64.5%). Conclusion: Many reports suggest that low-dose aspirin improve ovarian response, implantation rate, fertilization rate, implantation rate, and pregnancy rate by increasing the blood flow, but we couldn't prove the significant effect of low-dose aspirin on the IVF outcome except on endometrium. This may be affected by dose of aspirin, duration, and number of patients studied. This trial is small, so our results highlight the need for a large randomized controlled trial to identify the effect of low-dose as pirin on IVF-ET outcome.

젖소 유방염으로부터 분리한 그람음성균의 분포 및 항생제 감수성

이은실,강현미,정충일,문진산,Lee, Eun-Sil,Kang, Hyun-Mi,Chung, Chung-il,Moon, Jin-San 대한수의학회 2007 大韓獸醫學會誌 Vol.47 No.1

Environmental mastitis has increased particularly in well-managed or low somatic cell countherds that have successfully controled contagious pathogens. Major pathogens of environmental mastitisare Escherichia coli (E. coli) and Streptococcus uberis. The present study was conducted to investigate1,865 quaters of 241 Korean dairy farms from 2001 to 2004. Prevalence of major gram-negative bacteriaisolated from mastitis milk were E. coli (22.7%) and Enterobacter spp. (16.3%) in coliforms and Pseudomoassp. (10.3%) and Serratia spp. (7.9%) in non-coliforms. The results on antibiotic susceptibility by agardifusion test against these pathogens were 86.7% in piperaciliin, 94.6% in cefepime, 85.5% in amikacin,87.7% in gentamicin and so on. In contrast, the susceptibility against ampicillin (41.9%), cephalothin (9.9%),streptomycin (39.9%) and tetracycline (46.7%) appeared to be below 50%. Gram-negative bacteria showed(96.8%). Acording to year, distribution of high $256{\sim}64{\mu}g/ml$ on cephalothin get increased, but the othersare diferent. These findings demonstrate that major gram-negative bacteria were E. coli and Enterobacterspp. isolates, and often encountered the diverse antibiotic resistant patterns.

레몬 머틀 추출물을 첨가한 젤리의 품질 특성

이은실,이영주,김지현,전순실,Lee, Eun-Sil,Lee, Young-Ju,Kim, Ji-Hyun,Chun, Soon-Sil 한국식품영양학회 2020 韓國食品營養學會誌 Vol.33 No.2

This purpose of this study was to investigate the quality characteristics of jellies added with lemon myrtle extract. Lemon myrtle leaves were extracted for 0, 3, 5, 7, 9 minutes, respectively, in 90℃ water and used for jelly preparation. The moisture content of control showed the lowest value and the content increased significantly as the extraction time of lemon myrtle increased. The pH of L0 was significantly high and increased significantly with the increase of extraction duration time. The lightness value was the lowest in the L3. The redness showed the lowest value in the L9. The yellowness showed the lowest value in the L0. In texture properties the hardness of L9 showed the highest value and the lemon myrtle extraction duration increased significantly. The cohesiveness was highest in the L0 and lowest in the L5. Gumminess and chewiness increased significantly with increasing extraction duration. Total polyphenol content was the highest in the L5 and the jellies with lemon myrtle extracts were significantly higher than the L0. DPPH radical scavenging activities increased significantly with increasing extraction duration. The ABTS radical scavenging activity of the L0 was the lowest. In the sensory evaluation overall preference, color, sweetness, texture, and lemon myrtle flavor did not show any significant differences among the samples.

소아기 골 감염의 진단방법에 관한 조사

이은실,최광해,Lee, Eun Sil,Choi, Kwang Hae 대한소아감염학회 1997 Pediatric Infection and Vaccine Vol.4 No.2

목 적 : 골 감염의 조기 진단 및 적절한 치료는 감염의 만성화와 영구적 신체 장애를 예방하는데 중요하며, 조기 진단에는 동위 원소 검사가 가장 도움이 된다고 알려져 있다. 이에 저자는 세균학적으로 확진된 소아기 골 감염 환자들의 진단에 이용되었던 방법들을 검토하여 골 감염의 조기 진단에 가장 유용하였다고 생각되는 방법을 찾아 보고자 하였다. 방 법 : 1991년 1월부터 1997년 6월까지 6년 5개월간 영남대학교 의과대학 부속병원에 골 감염을 의심하여 입원했던 소아 환아 중 압통 부위 천자 후 검체를 배양하여 세균학적으로 증명된 급성 화농성 골수염 및 급성 화농성 관절염을 가졌던 29명을 대상으로 병록지 검토와 방사선학적 검사 및 동위원소 검사의 결과를 분석하는 후향적 연구를 시행하였다. 결과: 1) 대상 환아 29명의 연령 분포는 생후 4주 이내의 신생아가 5례(17.2%), 4주에서 l년 이내의 영아가 l례(3.4%), 1 세에서 15세 미만이 23례(79.3%)였고 남녀비는 1.4:1 이었다. 2) 진단시 진찰 소견으로는 국소 압통이 29례(100.0%) 전례에서 관찰되어 가장 흔한 소견이었고 그 외 환부종창, 관절 운동 제한, 열, 국소 열강 등의 순으로 많았으며 병적 골절도 1례에서 있었다. 3) 증상 발현 후 1주 이내 내원한 경우가 15례(51.7%)였고 29례(100.0%) 모두는 15일 이내에 내원하였다. 4) 검사소견으로 입원 당시 말초혈액 총 백혈구 수는 증가된 경우는 17례(58.6%)에 불과하였으나, 적혈구 침강 속도가 증가된 경우는 28례(96.6%)였고 CRP는 27례(93.1 %)에서 증가되었다. 5) 천자한 검체에사 배양된 균주는 Staphylococcus aureus가 전체 29례중에서 25례(86.0%)로 가장 많았다. 6) 단순 방사선 소견이 정상이거나 연부조직 종창만 보인 경우가 15례(51.7%), 골의 변화를 동반한 경우가 14례(48.3%)였다. 단순 방사선 소견이 정상이었던 환아 중에서 동위원소 검사를 시행했던 경우가 6례 있었으며, 이 중 동위 원소의 흡수 증가가 관찰된 경우가 5례였다 단순 방사선 검사상 비특이적 소견만 보인 1 례에서 시행한 골 자기 공명 촬영에서 골막하 농양이 관찰되었다. 결 론 : 골 감염의 조기 진단시 단순 방사선 검사에서 특이 소견을 관찰할 수 있는 경우는 48.3%에 지나지 않았고 동위 원소 검사 역시 6례 중 1례에서는 음성 소견을 보였다. 따라서 소아에서 임상적으로 골 감염이 의심되는 경우에는 압통 부위의 천자를 시행하여 세균학적 검사를 시행한 후 즉시 치료를 시작하는 것이 골 감염의 진단과 치료에 유용하다고 생각되며, 방사성 동위 원소 검사와 자기 공명 촬영이 조기 진단에 도움이 되는 검사이기는 하나 진단이 모호할 경우 치료를 시작한 후 시행해도 무방할 것으로 생각된다. Purpose: To prevent residual physical disability and chronic infection, prompt diagnosis and adequate treatment are important in the skeletal infections in children. Although radioisotope scanning is knwon as the method of choice for early diagnosis of bone infection, we conducted a study on twenty nine children who had skeletal infections to reevaluate the most appropriate way in diagnosis and management. Methods: A retrospective study was conducted on twenty nine children, who were admitted to the departments of Pediatrics and Orthopedic Surgery and who had acute osteomyelitis or septic arthritis, through review of medical records, radiologic & radioisotope study results. Their diagnoses were confirmed by bacteriologic cultures on the aspirated specimens from suspected bony lesions. Results: 1) Among twenty nine patients, there were 6 infants including 5 newborn infants, and 23 children were aged between 1 and 15 years. Male to female ratio was 1.4 to 1. 2) Point tenderness was noted in all cases, and the common physical signs were swelling, limitation of motion, fever and local heat in the order of frequency. 3) Fifty two percents of the patients were diagnosed within a week after onset of symptoms and all cases were within 15 days. 4) Leukocytosis was noted in only 58.6% of cases but erythrocyte sedimentation rate was increased in all cases except only one case. Staphylococcus aureus was revealed as the most common etiologic agent. 5) Radioisotope scans showed hot uptake in five of six cases(83.3%) who had no abnormal finding on plain skeletal radiolograms. Conclusions: Although radioisotope scan and MRI are helpful in early diagnosis before radiologic finding was detected on plain X-ray film, the antimicrobial therapy can be started after bacteriologic study of the aspirated specimens from the suspected skeletal lesions if skeletal infection is highly suspected clinically.

연구와 교육의 균형: 포항공대 대학교육개발센터 운영사례

이은실,Lee, Eun-Sil 한국대학교육협의회 2003 大學敎育 Vol.121 No.-

신경망을 이용한 언어장애인용 문장발생장치의 동사예측

이은실,민흥기,흥승홍,Lee Eunsil,Min Hongki,Hong Seunghong 한국융합신호처리학회 2000 융합신호처리학회 논문지 (JISPS) Vol.1 No.1

In this paper, we proposed a method which predict the verb by using the neural network in order to enhance communication rate in augmentative communication system for Korean language disorders. Each word is represented by an information vector according to syntax and semantics, and is positioned at the state space by being partitioned into various regions different from a dictionary-like lexicon. Conceptual similarity is realized through position in state space. When a symbol was pressed, we could find the word for the symbol at the position in the state space. In order to prevent verb prediction's redundancy according to input units, we predicted the verb after separating class using the neural network. In the result we can enhance $20\% communication rate in the restricted space

거대세포바이러스 대장염 환자에서 대장내시경에 의해 발생한 의인성 긴장 기복 1예

이은실 ( Eun Sil Lee ),장명국 ( Myoung Kuk Jang ),박소영 ( So Young Park ),이재형 ( Jae Hyung Lee ),이자영 ( Ja Young Lee ),임은주 ( Eun Ju Lim ),김형수 ( Hyung Su Kim ),이준호 ( Jun Ho Lee ),김경호 ( Kyung Ho Kim ),박용범 ( Yong 대한소화기학회 2006 대한소화기학회지 Vol.47 No.4

임화 시에 나타난"용기"의 양상과 의미

이은실 ( Eun Sil Lee ) 한국언어문화학회 2010 한국언어문화 Vol.0 No.43

This research aims to analyze the poetic change in Hwa Im``s early, middle, and late poems and its process to explore the aspect and meaning of ``courage`` portrayed in these poems. The poetic word ``courage`` in his poetry is a product of self-consciousness around the internal circumstances of the youth, the main agents of modern society; so, we need to analyze the word in details. In particular, the word ``courage`` is frequently used in his early and middle poems. Further, composed were many of poems which show a peculiar attitude toward ``courage`` although the poetic word ``courage`` is not used in those poems. After that time, the word ``courage`` in his early and middle poems shows an aspect that the word returns to his late poems through the process of poetic change. The word ``courage`` used in Im`s poetry has three aspects and meanings. First, other-directed courage is given by female mediators. This is mainly found in his early poems and means that the main agents have a correlation (i.e. close relations) with other people. The second one is bilateral ``courage`` as a twofold declaration (i.e. the agents` fear and will). It is a recurring aspect in his middle poems, and it reveals the insides of the main agents who fight a tough struggle. The final one is ex post ``courage`` (re)formed by the main agents` memory. This is an aspect which appears in his middle and late poems, and means the change of self-consciousness following other-directed ``courage`` and bilateral ``courage.`` The poetic word ``courage`` portrayed in Hwa Im`s poetry is a product of a poet`s self-consciousness which adopts the construction of historic confrontation will and self-identity as a method of overcoming bleak reality. In conclusion, the word ``courage`` dramatically does not act as a method of overcoming reality but it is a prototype which inspired the main agents constantly.

김수영의 시 「미농인찰지」에 나타난 주체 의식

이은실 ( Lee Eun Sil ) 한양대학교 동아시아문화연구소(구 한양대학교 한국학연구소) 2019 동아시아 문화연구 Vol.76 No.-

본 논문은「미농인찰지」가 김수영의 부정 정신과 관련하여 매우 중요한 텍스트라는 전제하에, 앞서 언급한 바와 같이 황현산이 김수영 시의 특별함이라고 말한 “현실에서 시를 추출하고, 현실로 시를 끌어올리는 이 능력”과 관련하여 시「미농인찰지」를 문제적 텍스트를 정립하고자 했다. 나아가 시「미농인찰지」를 자세히 읽기 위해 산문「민락기」를 교차적으로 살펴보았다. 시와 산문은 공통적인 경험을 바탕으로 하고 있지만, 일종의 의미적 균열을 내장하고 있는데, 여기서 중요한 지점이 바로 시에 나타나 있는 주체 의식이기 때문이다. 이를 위해 1장에서 김수영 시의 현재적 독법 요청을 위한 제언을 서술하였다. 2장에서는 편지의 수신인과 ‘미농인찰지’라는 기표에 대해 살펴보았다. 편지 쓰기 행위와 관련하여 매부라는 대타자에게 시적 주체 의식의 공백을 가리고자 하는 베일로 기능하고 있는 ‘미농인찰지’의 실패를 살펴보았다. 이를 통해 편지 쓰기 행위와 매부 그리고 미농인찰지가 갖는 가상적 지위를 살펴본다. 또한 대립물처럼 보이는 ‘밀용인찰지’가 주체의 생활이며 동일성을 갖게 되는 지점 그리고 그것을 인식하는 과정에 대해 알아보았다. 다음으로 3장에서는 편지 쓰기의 중단과 시적 개진의 교차 지점에 대해 살펴보았다. 시적 주체가 편지 쓰기를 중단할 수밖에 없는 심층의 원인이 ‘꽉 막히는 이것’의 기원 즉 여행에서 돌아오는 길에 대면하게 되는 ‘노동의 참경’ 및 식모가 갖는 타자성을 살펴보고 이에 대한 시적 주체의 의식을 분석한다. 끝으로 4장에서는 시적 주체가 타자 즉 ‘식모’를 부르는 행위와 관련하여, 그 무엇도 미안하지 않지만 식모를 부르는 단호한 목소리에 대해서는 미안하다고 언급하는 시적 주체를 통해 역설적 반성의 지점을 살펴보았다. 편지는 완성 중이며 끊임없이 마침표가 지연되는 상황을 통해 이는 부정정신과 관련지을 수 있으며, 결국 편지의 진정한 수신인이 시적 주체 자신이라는 것을 밝혔다. This article was intended to establish the poem 「Lined Rice Paper (Minonginchalji)」 as a problematic texts related to “This ability to extract the poem from the reality and to sublimate the poem to the reality”, the uniqueness of Kim Soo-Young’s poem according to Hwang Hyun-San, under the premise that 「Lined Rice Paper (Minonginchalji) 」 is very important text related to the negative spirit of Kim Soo-Young. And further, to read 「Line Rice Paper (Minonginchalji)」 carefully, the prose 「Minrakgi」 was examined as a cross-reference The poem and the prose were written based on common experience but they include the semantic cracks, because here, the important point is the sense of sovereignty appeared in the poem. To do that, in Chapter 1, the proposal for the modern reading of poem by Kim Soo-Young. In Chapter 2, the recipient and 「Lined Rice Paper (Minonginchalji)」, which are the signifier, were examined. And the failure of 「Lined Rice-Paper (Minonginchalji)」, which serves as veil to conceal the blank of poetic sense of sovereignty from the other, the brother-in-law, related to the act of writing letter, through which the hypothetical status of the act of writing letter, the brother-in-law and 「Minonginchalji」was examined. In addition, the point where 「Milyonginchalji」, which seems to be opposite, becomes the life of subject and has homogeneity, and the process of recognizing that point were examined. In Chapter3, the point where that writing the letter is stopped and that the poetic expression starts are crossed was examined. The origin of ‘this that the deep cause that the poetic subject cannot but stop writing the letter is blocked, that is, the terrible sight of labor’ and the otherness of housekeeper were examined and the consciousness of the poetic subject for that was analyzed. Finally, in Chapter 4, regarding the act of poetic subject's calling the other, that is, ‘housekeeper’, the point of paradoxical reflection was examined through the poetic subject who mentioned sorry about the forceful tone of calling the housekeeper although he does not feel sorry about anything. The situation that the letter is being completed and the period is being delayed endlessly can be related to the negative spirit, and after all, this article showed that the true recipient of the letter is the poetic subject itself.

부인암 환자의 생존단계별 건강증진행위, 외상 후 성장 및 삶의 질 비교

이은실(Lee, Eun Sil),박정숙(Park, Jeong Sook) 한국성인간호학회 2013 성인간호학회지 Vol.25 No.3