전신조사방사선치료 시 Isodose Structure를 이용한 Field-in-Field Technique의 유용성 평가

이윤희,반태준,이우석,강태영,백금문,Lee, Yoon Hee,Ban, Tae Joon,Lee, Woo Seok,Kang, Tae Young,Back, Geum Mun 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.1

목 적: 본원에서는 전신조사방사선치료 시 양 팔을 몸에 붙이고 누워있는 환자에게 좌우 양방향으로 방사선을 조사한다. 누운 자세는 기준점 두께에 대하여 신체 다른 부위와 두께 차이가 크기 때문에 보상체의 제작이 필요하고, 기준 깊이(Umbilicus) 처방선량에 대하여, 양팔(Arms)로 가려지지 않은 흉부와 복부 전면(Anterior)은 최대 20%까지의 선량차이가 나는 고 선량 영역이 된다. 이에 본 연구에서는 전신조사방사선치료 시 고 선량 영역과의 선량 차이를 줄일 수 있는 Isodose Structure를 이용한 Field-in-Field (FIF) Technique의 유용성을 평가 하고자 한다. 대상 및 방법: 인체모형등가팬텀(Rando Phantom, Alderson Resarch Laboratories Inc. Stamford. CT, USA, With Arm)으로 전산화단층촬영모의치료기의 영상을 획득하여 FIF와 납(Pb) 보상체를 이용한 전산화치료계획(Eclipse, version 10.0, Varian, USA)을 수립하였다. 두 치료계획의 흉부와 복부 부위의 선량분포를 비교하고, 수립된 치료계획을 이용하여 인체모형등가팬텀에 선량을 조사한 후, 열형광선량계(thermoluminescence dosimeter, TLD)와 필름(Film)을 이용하여 측정하였다. 결 과: 두 치료계획을 비교해 본 결과 기준깊이 처방선량에 대하여 팔로 가려지지 않은 흉부와 복부 전면의 선량차이는 FIF에서는 106~107%, 납 보상체를 이용한 치료계획에서는 114~124%였다. 열형광선량계를 분석한 결과로 FIF에서는 104~107%, 납 보상체를 이용한 치료계획에서는 110~117%의 기준깊이 처방선량과의 선량차이가 나왔다. 결 론: 본 실험에서 인체모형등가팬텀에 양 팔을 제작하여 치료 계획 및 선량을 조사해 보았다. 양 팔의 투과 유무에 따라 약 7~17%의 선량차이가 발생 하였다. 4단계의 FIF 기법으로 3차원 치료계획을 수립하여 전신에 약 95~107%의 균등한 선량 분포를 확인하였고 ${\pm}10%$ 이내의 선량 균일성을 유지 할 수 있을 것으로 분석 되었다. FIF 기법을 이용한 3차원 치료 계획은 환자 전신에 조사되는 선량을 미리 분석 할 수 있는 치료 계획으로 기존 치료 방법보다 균등한 선량의 전달이 가능할 것으로 사료된다. Purpose: In Asan Medical Center, Two parallel opposite beams are employed for total body irradiation. Patients are required to be in supine position where two arms are attached to mid axillary line. Normally, physical compensators are required to compensate the large dose difference for different parts of body due to the different thicknesses compared to the umbilicus separation. There was the maximum dose difference up to 30% in lung and chest wall compared to the prescription dose. In order to resolve the dose discrepancy occurring on different body regions, the feasibility of using Fieid-in-Field Technique is investigated in this study. Materials and Methods: CT scan was performed to The RANDO Phantom with fabricated two arms and sent to Eclipse treatment planning system (version 10.0, Varian, USA). Conventional plan with physical lead compensator and new plan using Field-in-Field Technique were established on TPS. AAA (Anisotropic Analytical Algorithm) dose calculation algorithm was employed for two parallel opposite beams attenuation. Results: The dose difference between two methods was compared with the prescription dose. The dose distribution of chest and anterior chest wall uncovered by patient arms was 114~124% for physical lead compensator while Field-in-Field Technique gave 106~107% of the dose distribution. In-vivo dosimetry result using TLD showed that the dose distribution to the same region was 110~117% for conventional physical compensator and 104~107% for Field-in-Field Technique. Conclusion: In this study, the feasibility of using FIF technique has been investigated with fabricated arms attached Rando phantom. The dose difference was up to 17% due to the attached arms. It is shown that the dose homogeneity is within ${\pm}10%$ with the CT based 3-dimensional 4 step FIF technique. The in-vivo dosimetry result using TLD was showed that 95~107% dose distribution compared to prescription dose. It is considered that CT based 3-dimensional Field-in-Field Technique for the total body irradiation gives much homogeneous dose distribution for different body parts than the conventional physical compensator method and might be useful to evaluate the dose on each part of patient body.

동원(東垣) ${\ll}$비위론(脾胃論)${\gg}$ 수록(收錄) 처방(處方)의 치법(治法)에 대(對)한 문헌적(文獻的) 고찰(考察)

이윤희,황희정,김상찬,박순달,변준석,Lee, Yun-Hee,Hwang, Hui-Jeung,Kim, Sang-Chan,Park, Soon-Dal,Byun, Joon-Seok 대한한의학방제학회 2001 大韓韓醫學方劑學會誌 Vol.9 No.1

Objectives : 'Pi Wei Lun' is the principal medical work of Li Dongyuan's writings, which contains most of his medical theories. There are sixty-three prescriptions in 'Pi Wei Lun', and fifty-two of them were originated from him. This study was planned to present assistance to those who apply Dongyuan's theory clinically. Methods : We investigated those fifty-two prescriptions literary, and studied them from a viewpoint of the principle and method of treatment. Results : Dongyuan's fifty-two prescriptions can be classified into eight groups from the viewpoint of the principles and methods of treatment which are composed of 'tonify the spleen and stomach & elevate the spleen Yang', 'elevate the spleen Yang & expel fire', 'elevate the spleen Yang & relieve dampness', 'promote blood flow to eliminate blood stasis', 'invigorate the spleen', 'replenish Ki & and dispel phlegm', 'purgation with drugs warm in nature', and 'the other' eight methods. Conclusions : From above, we concluded that Dongyuan considered 'the primordial energy of the spleen and stomach' as the most important when making up prescriptions, but, at the same time, he used diverse methods of treatment on the ground of differentiation of syndromes.

나노 압입곡선의 이론적 분석을 통한 박막의 잔류응력 평가

이윤희,장재일,권동일,Lee, Yun-Hee,Jang, Jae-Il,Kwon, Dong-Il 대한기계학회 2002 大韓機械學會論文集A Vol.26 No.7

Residual stress is a dominant obstacle to efficient production and safe usage of device by deteriorating the mechanical strength and failure properties. Therefore, we proposed a new thin film stress-analyzing technique using a nanoindentation method. For this aim, the shape change in the indentation load-depth curve during the stress-relief in film was theoretically modeled. The change in indentation depth by load-controlled stress relaxation process was related to the increase or decrease in the applied load using the elastic flat punch theory. Finally, the residual stress in thin film was calculated from the changed applied load based on the equivalent stress interaction model. The evaluated stresses for diamond-like carbon films from this nanoindentation analysis were consistent with the results from the conventional curvature method.

멀티미디어 시대의 대학

이윤희,Lee, Yun-Hui 한국대학교육협의회 1997 大學敎育 Vol.85 No.-

간호대학생의 인유두종바이러스 접종 의도 및 영향요인: 계획된 행동이론을 기반으로

이윤희,박금옥,Lee, Yoon-Hee,Park, Keum-Ok 한국융합학회 2021 한국융합학회논문지 Vol.12 No.9

본 연구는 계획된 행동이론을 적용하여 간호대학생의 인유듀종바이러스(Human Papilloma Virus, HPV) 예방접종 의도를 파악하고, 관련 요인을 알아보기 위함으로 D광역시에 소재한 간호대학에 재학중인 학생을 대상으로 총 195명의 자료를 수집하였다. SPSS 25.0 program을 이용하여 분석한 결과, 대상자의 HPV 예방접종 의도는 5.24±1.66(7점 척도)이었으며, HPV 예방접종 의도에 태도(β=.446 p<.001), 주관적 규범(β=.134, p=.041), 지각된 행동 통제(β=.321, p<.001) 모두 유의미한 영향을 미치는 것으로 나타났다. 이들 변수는 대상자의 HPV 예방접종 의도를 54.4% 설명하였다. 본 연구결과 바탕으로 HPV 예방접종에 대한 긍정적인 태도를 가지고, HPV 예방접종을 용이하게 할 수 있는 정책 및 접종을 독려하기 위한 프로그램이 요구되며, 본인의 접종 및 미래의 간호교육자로서의 성교육과 홍보활동을 위한 교육이 필요하다고 사료된다. The purpose of this study was to apply Ajzen's theory of planned behavior to identify factors that affect nursing students decisions to receive Human Papilloma Virus(HPV) vaccination. Data collection was done using self-report questionnaires with 195 nursing students in D city. Data were analyzed using percentage, mean, standard deviation, t-test, Pearson correlation analysis and hierarchial regression with the SPSS Win 25.0 Program. The mean score of intention to receive HPV vaccine was 5.24±1.66 out of a possible 7. In the hierarchial regression analysis, attitudes (β=.446, p<.001), perceived behavior control (β=.321, p<.001) subjective norm (β=.132, p=.041), to receive HPV vaccine were significant predictors and explained 54.4% of intention to receive HPV vaccine. it is suggested that promotion programs and social environment to encourage to think it positively and perceive it easy and convenient should be developed, with nursing students' educatinon for sex education and public relations activitiesas as a nursing educators.

연속압입시험법을 이용한 재료의 강도 , 잔류응력 및 파괴인성 평가

이윤희,이정환,옥명렬,안정훈,권동일 ( Yun Hee Lee,Jeong Hwan Lee,Myoung Ryul Ok,Jeong Hoon Ahn,Dong Il Kwon ) 대한금속재료학회 ( 구 대한금속학회 ) 1997 재료강도 심포지엄 Vol.- No.-

근대 건축물에 사용된 서양식 목조 지붕 트러스의 구조요인 및 기타 영향요인에 관한 연구 - 공공기관이 관리하는 문화재 중 근대건축물 기록을 중심으로 -

이윤희,유혜란,권기혁,Lee, Yoon-Hee,Yu, Hye-Ran,Kwon, Ki-Hyuk 한국건축역사학회 2011 건축역사연구 Vol.20 No.4

Western style timber roof trusses used as typical roof structures of buildings during a modern period have been developed with the interactions with their facade and functionality. The shapes of trusses and member sizes have been diversely changed by the purposes of architects, historical circumstances, and structural characteristics. For this reason, the change in the shapes of western style timber trusses along the times is one of important technology assets demonstrating the development of their structures during the modern period. Therefore, the purpose of this paper is to find out their structural characteristics throughout parametric analysis of which parameters were determined from the collected and classified documents on western style timber roof structure built in the modern period carefully obtained from public institutions. Results of the parametric analysis are as follows. The number of king-post trusses and modified king-post trusses built between 1920 and 1937 reaches almost half of the total number of truss types investigated. The mean values of their spans, distances, tributary areas, and height are respectively, 10.5m, 2.4m, $24.37m^2$and 3.24m. The cross-section areas of trusses tend to reduce since the city construction law was enacted in 1920. Also, this study found that western architects usually used larger structural members than eastern architects and usages and finishing materials of roof trusses are not always considered as one of the important design parameters.

교류자기장에 의한 유도가열체를 이용한 평판 디스플레이용 COG (Chip On Glass) 접속기술

이윤희,이광용,오태성,Lee Yoon-Hee,Lee Kwang-Yong,Oh Tae-Sung 한국마이크로전자및패키징학회 2005 마이크로전자 및 패키징학회지 Vol.12 No.4

교류자기장에 의한 유도가열체를 이용하여 LCD 평판 디스플레이 패널의 가열을 최소화하면서 IC 칩을 실장시킬 수 있는 COG 접속기술에 대해 연구하였다. 크기 5mm${\times}$5mm, 두께 $600{\mu}m$의 Cu 도금막으로 제조한 유도가열체에 14 kHz, 230 Oe의 교류자기장을 인가시 60초 이내에 유도가열체의 온도가 Sn-3.5Ag 무연솔더의 리플로우에 필요한 $250^{\circ}C$에 도달하였으며, 유도가열체로부터 2 mm 떨어진 부위에서부터 기판의 온도는 $100^{\circ}C$ 이하로 유지되었다. 이와 같은 Cu 도금막 유도가열체에 14 kHz, 230 Oe의 교류자기장을 120초 동안 인가하여 Sn-3.5Ag 솔더범프를 리플로우 시켜 COG 실장을 하는 것이 가능하였다. Chip-on-glass technology to attach IC chip directly on the glass substrate of flat panel display was studied by using induction heating body in AC magnetic field. With applying magnetic field of 230 Oe at 14 kHz, the temperature of an induction heating body made with Cu electrodeposited film of 5 mm${\times}$5 mm size and $600{\mu}m$ thickness reached to $250^{\circ}C$ within 60 seconds. However, the temperature of the glass substrate was maintained below $100^{\circ}C$ at a distance larger than 2 mm from the Cu induction heating body. COG bonding was successfully accomplished with reflow of Sn-3.5Ag solder bumps by applying magnetic field of 230 Oe at 14 kHz for 120 seconds to a Cu induction heating body of 5mm${\times}$5mm size and $600{\mu}m$ thickness.

PWR 사용후핵연료의 Li 환원과정 모사 프로그램 개발

이윤희,신희성,장지운,김호동,윤지섭,Lee, Yun-Hee,Shin, Hee-Sung,Jang, Ji-Woon,Kim, Ho-Dong,Yoon, Ji-Sup 한국방사성폐기물학회 2006 방사성폐기물학회지 Vol.4 No.4

In this paper a computer program was developed, which simulates the Li reduction process of PWR spent fuel, and the amount of a produced metal or chloride compound was calculated at the various amount of Li with the program. It establishes a database, which is composed of some characteristics related to a chemical reaction equation and thermodynamic data, and it calculates the transformed rate of PWR spent fuel oxide at the certain amount of Li by using the database as input data. As the results of the performance test of the program, it was validated that the transformed values of oxides, except for $Eu_2O_3$ and $Sm_2O_3$, were almost the same to within about a 6 % error with those calculated by the previous code and that the calculated amount of Li was also exactly consistent with the theoretical one, which is used for a complete reaction of each oxide in a single chemical reaction. A relationship between Li and the transformed metal of each oxide was analyzed on the basis of the quantities calculated with the verified development program. Of the results, when the amount of Li was given to be 250 mole, the 83.73 percentage of $UO_2$ was transformed into U while the remainder was still to be $UO_2$. In addition, it was appeared that the 297 mole of Li was needed to completely convert $UO_2$ into U.

한국 성인의 심혈관질환에 영향을 미치는 위험요인: 요코티닌을 포함한 흡연행태 및 건강행태를 중심으로

이윤희,곽은미,조미래,Lee, Yoon Hee,Kwak, Eun Mi,Jo, Mirae 국제문화기술진흥원 2021 The Journal of the Convergence on Culture Technolo Vol.7 No.3

본 연구는 국민건강영양조사 제7기 2016~2018년도 자료를 이용하여 우리나라 성인의 심혈관질환 유병에 영향을 미치는 요인에 대해 규명하고자 하였다. 연구대상자는 7,290명, 자료는 SPSS 26프로그램으로 복합표본 빈도분석, 교차분석, 로지스틱 회귀분석을 실시하였다. 주요 결과로 40~59세 9.0배, 60세 이상 29.44배, 고졸 이하 1.26배, 소득수준 '하' 1.68배, 요코티닌 50ng/mL 미만 1.54배, 50~499.9ng/mL 1.56배, 하루 평균 흡연량 20개비 이상 1.48배, BMI 25kg/m² 이상 2.06배, 유산소운동을 실천하지 않는 경우 1.17배 심혈관질환 유병을 유의하게 증가시키는 것으로 확인되었다. 이상의 결과로 우리나라 성인의 심혈관질환 유병정도를 감소시키기 위해 흡연을 포함한 비만, 운동부족의 생활습관 개선이 필요하며, 고혈압, 이상지혈증등의 유병기간이 길어진 40세 이상의 연령층, 사회경제적 수준이 낮은 층에게 금연을 포함한 건강관리에 대한 적극적인 노력이 요구된다. This study was to find out the influence of urine cotinine in Korean adults on Cardiovasculardiseases using data from the seventh Korea national health and nutrition examination survey 2016-2018. The subjects were 7,290. The data were analyzed by frequency analysis, 𝞆2 test and logistic regression analysis using SPSS 26. The main findings were that 40-59 age, higher than 60 age, lower than high school level, Income status low, urine cotinine level under 50ng/mL, urine cotinine level 50-499ng/mL, Average cigarette per day over the 20 loosey, BMI 25g/m², no aerobic exercise, the prevalence of cardiovascular disease increased 9.0 times, 29.44 times,1.26 times, 1.68 times, 1.54 times, 1.56 times, 1.48 times, 2.06 times and 1.17 times, respectively. As a result, it is necessary to improve lifestyles such as obesity and lack of exercise, to reduce the prevalence of cardiovascular disease in Korean adults, and to pay attention to older age groups and low socioeconomic groups.