지역약국 방문 성인 환자의 Acetaminophen 사용 현황 평가

이유정(Yu Jeung Lee) 대한약학회 2010 약학회지 Vol.54 No.3

Acetaminophen is one of the most commonly used over-the-counter medication in Korea. It is a safe and effective medication for the treatment of mild to moderate pain or fever when used in therapeutic doses. However, acetaminophen overdose is a frequent cause of acute liver failure. The purpose of this study was to evaluate the acetaminophen use for adult patients at community pharmacies in Korea. This study was a 11-questionnaire survey conducted from December 15, 2009 to January 5, 2010. Of the 204 respondents, 117 (57.4%) had used acetaminophen products within 6 months. Only 20 (9.8%) reported having knowledge about the daily maximum doses of acetaminophen, and 3 out of 20 knew it correctly. Only 10 (4.9%) reported having knowledge about the potentialtoxicity of acetaminophen overdose, and 7 out of 10 knew that acetaminophen overdose could cause liver toxicity. The results of this study indicates a need for pharmacists to educate patients regarding the appropriate doses and potential toxicities of acetaminophen.

지역약국 방문 성인의 제네릭 의약품 인식도 평가

이유정(Yu Jeung Lee) 대한약학회 2011 약학회지 Vol.55 No.3

Generic medication market has been increased for economic reasons in Korea. Health authorities worldwide recommend the use of generic medications nowadays. However, patients in Korea are not familiar with the generic medications and considerable percent of those do not know the definition of the generic medications. The purpose of this study was to evaluate adults' knowledge and perception on the generic medications at community pharmacies in Korea. This study was a 11-questionnaire survey conducted from August 9, 2010 to August 27, 2010. Of the 204 respondents, 63 (30.9%) responded that they knew what a generic medication was, but only 16 (25.4%) of those answered that generic medications had the same efficacy as brand medications. When pharmacists were the source of generic medication information, more patients reported having knowledge about the definition of generic medications correctly compared with other sources. Patients with negative experience with generic medications within 6 months were more reluctant to generic substitution suggested by a pharmacist than those with positive experience. Based on the results of this study, further studies should be conducted to establish the best way to provide generic medication information for patients.

외래 환자들의 의약품 정보원과 선호도 분석

이유정(Yu Jeung Lee) 大韓藥學會 2010 약학회지 Vol.54 No.4

Appropriate drug information is essential in pharmaceutical care practice. In recent years, educating patients with their prescription and drug therapy is becoming an increasingly important aspect of health care. Appropriate drug information has been shown to improve patients’ adherence to their medication and the results of pharmacotherapy. The purpose of this study was to study patients’ sources of drug information and their preferences in Korea. This study was a 11-questionnaire survey conducted from February 8, 2010 to February 25, 2010. Major sources of drug information used by respondents, proportions of respondents who received drug information on administration, dosage, indication, or warnings and precautions, sources of drug information which patients prefer, and the reasons of their preferences were studied. Of the 303 respondents, the most common sources of drug information were pharmacists (29.7%), doctors (23.8%), and the Internet (17.2%). There were significant differences according to sources of drug information in proportions of respondents who received drug information on administration, dosage, indication, or warnings and precautions. Patients preferred pharmacists as a drug information source the most (38.9%), and the reasons were reliability (72.0%) and easy to use (28.0%). Based on the results of this study, further studies should be conducted to establish the best way to provide appropriate drug information for patients and improve the results of pharmacotherapy.

방사선 검사에 사용되는 조영제 Iopamidol의 안전성 평가

박창묵(Chang Mook Park),이명구(Myung Koo Lee),송태범(Tea Bum Song),이보름(Bo Reum Lee),임성실(Sung Cil Lim),장제관(Je Kwan Jang),이유정(Yu Jeung Lee) 대한약학회 2009 약학회지 Vol.53 No.6

Contrast media are substances that are used to enhance the contrast of structures or fluids within the body in medical imaging. Those are commonly used to enhance the visibility of blood vessels and the gastrointestinal tract. The aim of this study is to evaluate patients who got injected iopamidol, developed as one of contrast medium regarding changes in cardiovascular system and especially, adverse drug reactions. This study were performed on randomly selected a total of 51 patients (range of 15~85 years old) who got injected contrast medium, Iopamidol at a P hospital in Gyeonggi province from September 22nd, 2008 to January 24th, 2009. Data were collected by questionnaire though person to person. We analyzed the data by SPSS (Version 12. for windows). Methods of analysis were frequency and cross analysis. In results, 19.6% (n=10) were founded for adverse drug reactions of contrast medium. 25.0% (n=4) of 10 patients who had adverse drug reactions of contrast medium had took abdomen contrast test. 2 patients of those took contrast test for chest. Also, 3.9% (n=2) patients felt vomiting and nausea after injection of contrast medium. In conclusion, 19.6% patients experienced adverse drug reaction of contrast medium. Therefore, when taking radiation test, we should make efforts to minimize adverse drug reactions to achieve suitable and effective treatment.

노인 환자에서 Vancomycin 사용과 관련한 신독성의 위험인자 연구

김하늬,김해숙,이양현,이경주,신승우,박선철,이유정,Kim, Ha Nui,Kim, Hae Sook,Lee, Yang Hyun,Lee, Kyeong Ju,Shin, Seung Woo,Park, Seon Cheol,Lee, Yu Jeung 한국임상약학회 2017 한국임상약학회지 Vol.27 No.1

Objective: Infection is very common in the elderly, so there is a high prevalence of antibiotics use among this population. Especially, due to the emergence of resistant bacteria, the use of vancomycin is growing. The purpose of this study was to evaluate risk factors associated with vancomycin-induced nephrotoxicity in elderly patients. Methods: The subjects of this study were patients over 18 years old who received intravenous vancomycin in a general hospital located in Gangneung-si, Korea between August 1, 2013 and July 31, 2015. Data collection regarding vancomycin use and baseline characteristics was conducted using computerized hospital database. Logistic regression analysis was used to identify risk factors associated with vancomycin-induced nephrotoxicity. Results: A total of 290 patients were finally included, and 191(66%) out of these patients were age 65 or older. The incidence of vancomycin-induced nephrotoxicity was 11.0%, 12.6%, and 7.0% in the all adult patients, the elderly patients, and the non-elderly patients, respectively. There were significant differences in comorbidities between patients with nephrotoxicity and patients without nephrotoxicity in the all adult patients, and there were significant differences in vancomycin duration, comorbidities, and number of nephrotoxic agents between patients with nephrotoxicity and patients without nephrotoxicity in the elderly patients. However, according to the logistic regression analysis, there was no significant risk factor that increases the incidence of vancomycin-induced nephrotoxicity in all three age groups. Conclusion: There were no differences in risk factors that increase the incidence of vancomycin-induced nephrotoxicity between all adult patients, elderly patients, and non-elderly patients. Further studies with larger sample sizes to identify risk factors associated with vancomycin-induced nephrotoxicity in the elderly to improve the outcome of pharmacotherapy are required.