딥러닝을 활용한 엣지 컴퓨팅 기반 산업현장 작업자 행동 분석 시스템

이세훈(Se-Hoon Lee),박정준(Jeong-Jun Bak),이태형(Tae-Hyeong Lee) 한국컴퓨터정보학회 2020 한국컴퓨터정보학회 학술발표논문집 Vol.28 No.1

조사료와 농후사료의 급여 순서가 In vitro 반추위 발효성상, 총 가스 발생량과 메탄 발생량에 미치는 영향

이유경,이성실,성필남,이슬,백열창,김기현,이성대,천주란,지상윤,김정은,Lee, Yookyung,Lee, Sungsill,Seong, Pilnam,Lee, Seul,Baek, Youlchang,Kim, Kihyun,Lee, Sungdae,Chun, Julan,Ji, Sangyun,Kim, Jungeun 한국초지조사료학회 2021 한국초지조사료학회지 Vol.41 No.2

본 연구는 국내 고유종인 한우에서 1) 농후사료 급여 후 조사료 급여, 2) 조사료 급여 후 농후사료 급여, 3) TMR 급여의 총 세 가지 형태의 사료급여가 반추위 발효성상, 총 가스 및 메탄 발생량에 미치는 영향을 in vitro로 평가하기 위해 수행되었다. 사료 급여 형태에 따라 반추위 환경이 변화할 것으로 가설을 세우고, 옥수수 (M)와 티모시 (T)를 기질로 하여 반추위액의 24시간 in vitro 배양을 실시하였다. 따라서 시험 처리구는 총 6개로 구성되었다: M1, M2, M3, T1, T2, T3. 반추위 pH는 사료 급여방식 2에서 다른 처리구보다 높았고 (P < 0.001), 티모시 기질에서 옥수수 기질보다 높았다 (P < 0.001). 휘발성 지방산 (VFA; volatile fatty acid) 조사항목들 (Total VFA, acetate, propionate, butyrate, valerate)은 사료 급여방식 1에서 가장 높았고 급여방식 2에서 가장 낮았으며 (P < 0.001), 옥수수 기질에서 더 많이 생산되었다 (P < 0.001). 반추위액 내 acetate:propionate 비율은 사료 급여방식에 따른 효과는 없었으나 (P = 0.116), 티모시 기질이 옥수수 기질보다 더 높은 값을 나타냈다 (P < 0.001). 암모니아태 질소 (NH₃-N)는 사료 급여방식 1에서 다른 처리구보다 높았으며(P < 0.001), 티모시 기질에서 높은 수치를 보였다 (P < 0.001). 총 가스 및 메탄가스 발생량은 사료 급여방식 1에서 가장 높았고(P < 0.001), 옥수수 기질에서 더 많이 생산되었다 (P < 0.001). 메탄은 이산화탄소의 20배 이상의 지구온난화효과를 갖는 것으로 알려져 있고, 반추가축이 섭취한 에너지의 손실로 작용하고 있어 장내발효 메탄 발생량을 저감하는 것은 매우 중요한 과제라 할 수 있다. 반추가축에서 사료급여 방식에 따른 메탄 발생량 차이에 대한 결론을 얻기 위해서는 보다 다각적인 형태의 연구가 필요할 것으로 사료된다. The objective of this study was to evaluate effects of feeding methods on in vitro ruminal fermentation, total gas and methane production in Hanwoo steers. Six Hanwoo steers fitted with rumen cannula (430 ± 21 kg of body weight) were randomly assigned to one of three feeding systems: 1) feeding forage 1 hour after concentrate, 2) feeding concentrate 1 hour after forage, 3) feeding mixed ration. Rumen fluid sampled from each animals was incubated 24 hours with maize or timothy substrates in in vitro. Ruminal pH was increased in feeding method 2 or maize substrate than that of other methods or timothy substrate (P < 0.001). The production of total volatile fatty acid, acetate, propionate, butyrate, and valerate were increased when steers fed diets using feeding method 1 or rumen fluid was incubated with maize substrate (P < 0.001). Increased production of total gas and methane was observed in feeding method 1 and maize substrate compared to those of other methods or timothy substrate (P < 0.001). Due to the inconsistent results between ruminal fermentation and gas production in this study, further research is required to estimate effects of feeding method on enteric fermentation and gas production in in vivo.

Chryseobacterium sp. JK1이 분비하는 세포외 단백질분해효소 특성

이유경,오지성,노동현,Lee, Yu-Kyong,Oh, Ji-Sung,Roh, Dong-Hyun 한국미생물학회 2013 미생물학회지 Vol.49 No.1

이전의 연구에서 토양으로부터 많은 양의 세포외 단백질분해 효소를 생산하는 신종 중온세균 Chryseobacterium sp. JK1를 분리하였다. 이 균주가 생산하는 단백질 분해효소의 특성조사 결과 최적반응온도와 pH는 각각 $40^{\circ}C$와 7.0이였으며, 좁은 최적온도 구간과 비교적 넓은 pH 구간인 pH 6.0-9.0에서 높은 활성을 보여주었다. 그리고 단백질 분해효소는 EDTA 또는 EGTA, PMSF와 금속이온 $Ag^+$ 또는 $Cu^{2+}$의 첨가에 의해 강하게 저해 되었으며, $Al^{3+}$의 첨가에 의해 약하게 저해되었다. Pepstatin과 금 속이온 $K^+$, $Ca^{2+}$, $Na^+$, $Fe^{2+}$ 또는 $Mg^{2+}$의 첨가는 저해에 큰 영향을 주지 않았다. 이와 반대로 단백질분해효소는 이가 금속이온인 $Mn^{2+}$ (5 mM)의 첨가에 의해 효소활성이 향상되었다. 농축된 배양 상등액의 활성염색 분석으로 67과 145 kDa 크기의 주요 밴드 두 개가 관찰되었다. 이러한 결과들로 Chryseobacterium sp. JK1 균주가 식품산업에 응용 가능한 세포외 중성의 serine 단백질 분해효소를 생산한다는 것을 알 수 있었다. A novel Chryseobacterium sp. JK1 strain isolated from soil had been reported that this isolate produced large amount of extracellular protease at mesophilic temperature in previous study. The optimal temperature and pH of extracellular protease were $40^{\circ}C$ and 7.0, respectively, showing narrow range of optimal temperature and relatively broad activity from pH 6.0 to 9.0. In addition, the protease showed greatest activity against skim milk and lowest against bovine serum albumin (BSA). The protease strongly inhibited by ethylenediaminetetraacetic acid (EDTA), ethylene glycol tetraacetic acid (EGTA) or phenylmethylsulfonyl fluoride (PMSF), and addition of cation $Ag^+$ or $Cu^{2+}$, and slightly inhibited by $Al^{3+}$. No significant inhibition was found with pepstatin, and addition of cation, $K^+$, $Ca^{2+}$, $Na^+$, $Fe^{2+}$ or $Mg^{2+}$. On the contrary, protease was enhanced by addition of divalent cation $Mn^{2+}$ (5 mM). Zymography analysis of concentrated culture supernatant revealed two major bands at 67 and 145 kDa. These results suggest that Chryseobacterium sp. JK1 strain produced extracellular neutral serine proteases which could apply in food industry.

김치의 국제식품규격 승인의 의미

이유경,Lee, Yu-Gyeong 한국식품연구원 2000 食品技術 Vol.13 No.3

Variation in Fucoidan Contents and Monosaccharide Compositions of Korean Undaria pinnatifida (Harvey) Suringar (Phaeophyta)

이유경,임동정,이윤희,박용일,Lee, Yoo-Kyung,Lim, Dong-Jung,Lee, Yoon-Hee,Park, Yong-Il The Korean Society of Phycology 2006 ALGAE Vol.21 No.1

Three different forms of Undaria pinnatifida, the southern form (U. pinnatifida f. typica), the northern form (U. pinnatifida f. distans), and Samcheok form (recently cultivated strain), were examined for the contents and compositions of fucoidans. Fucoidans were extracted from the dried edible portions of three forms of U. pinnatifida in low pH condition, mainly by ethanol precipitation and CaCl2 treatment. It was shown that Samcheok form contains 1.8 and 3.5 times more fucoidans than the northern and the southern forms, respectively. The monosaccharide compositions of individual fucoidans were also varied. The fucoidans from the southern and the northern forms were shown to be composed of mainly fucose and galactose with the molar percentage ratios of 83.5%:16.5% and 87.4%:12.6%, respectively, indicating that these are F-type fucoidans. The fucoidan from Samcheok form, however, consisted of fucose (62.7%), galactose (32.9%), and small amount of glucose (4.4%). The results of this study showed that both amount and monosaccharide compositions of fucoidans are variable depending on U. pinnatifida forms.

Real-world Adverse Events Associated with Fluconazole and Itraconazole: Analysis of Nationwide Data Using a Spontaneous Reporting System Database

이유경,이정민,천부순,Lee, Yu gyeong,Lee, Jungmin,Chun, Pusoon Korean College Of Clinical Pharmacy 2022 한국임상약학회지 Vol.32 No.3

Objective: This study aimed to investigate the occurrence and types of the adverse events (AEs) associated with oral fluconazole and itraconazole and factors associated with specific types of AEs. Methods: We analyzed AEs reported by community pharmacies nationwide over 10 years using the Korea Adverse Event Reporting System database. Various AE terms were categorized into 18 types, and concomitant medications were classified by drug-drug interaction (DDI) severity. The relationship between the specific type of AE and age, sex, and number of concomitant medications was investigated using multiple logistic regression analysis. Results: A total of 879 AE reports of fluconazole and 401 reports of itraconazole were analyzed; of these reports, 321 and 83 reports of fluconazole and itraconazole, respectively, described concomitant drug administration categorized as DDI severity of contraindicated or major. Women had a higher risk of psychiatric AEs associated with fluconazole use (OR, 1.587; p=0.042). Polypharmacy increased the risk for psychiatric AEs (OR, 3.598; p<0.001 for fluconazole and OR, 2.308; p=0.046 for itraconazole). In dermatologic AEs, the mean age of patients who received itraconazole was lower than that of patients who received fluconazole (46.3±16.8 vs. 54.9±15.4; p<0.001). Co-administration of fluconazole with 1-3 drugs increased the risk of neurological AEs (OR, 1.764; p=0.028). Conclusion: When using fluconazole and itraconazole, psychiatric AEs should be noted, particularly in women and in case of polypharmacy; moreover, when fluconazole is co-administered with other drugs, attention should be paid to the occurrence of neurological AEs.

행지(行遲)로 진단된 하지부 운동발달지연 환아의 치험 1례 보고

이유경,채중원,Lee, Yu-Gyoung,Chae, Jung-Won 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.3

Objectives This is the clinical report about 1 case of patient with delayed motor development in lower limbs. Methods The herb medication, acupuncture therapies were applied for treating delayed motor development from June 9 to November 20, 2007. Results After 5 months treatment, the patient's delayed motor development were improved by oriental medical therapy. Conclusions We report the good results of oriental medical therapy on a pediatric patient with delayed lower limbs motor development. For more accurate studies, further studies would be needed with more cases.

연근(蓮根)이 Steptozotocin으로 유발된 당뇨병(糖尿病) 백서(白鼠)의 혈당(血糖) 및 혈중(血中) 지질(脂質)에 미치는 영향

이유경,채중원,Lee, Yu-Gyoung,Chai, Jung-Won 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.2

Objectives : This study was designed to investigate the effects of Nelumbinis Rhizomatis Nodus(NRN) on production levels of Blood Glucose and Serum Lipid Levels. Methods : This study is about changes of blood glucose levels, body weights, levels of food and water uptake, levels of total cholesterol in the body, triglyceride, Creatinine, and BUN production by NRN extract. Results : Treatment with NRN regulated blood glucose levels effectively, but treatment with NRN did not affect body weights, food and water uptake. In addition, treating with NRN also lowered levels of total cholesterol, which is important for diabetes, and also lowered levels of triglyceride, too. Serum Creatinine levels were not affected, but serum BUN levels were lowered by treating with NRN, which were elevated in diabetes. Conclusions : These results demonstrate that NRN is effective to treat DM level and also has anti-hyperlipidemic effect.

반점각막이상증, TGFBI각막이상증, 푹스각막이상증 환자의 전층각막이식술 후 장기 예후

이유경,김만수,You Kyung Lee,Man Soo Kim 대한안과학회 2012 대한안과학회지 Vol.53 No.10

Purpose: To compare long-term outcomes of penetrating keratoplasty in treating macular corneal dystrophy, transforming growth factor beta induced (TGFBI) dystrophy, and Fuchs’ dystrophy. Methods: The present retrospective study describes the postoperative results of 123 eyes in 70 patients; 53 eyes with macular corneal dystrophy, 20 eyes with TGFBI dystrophy, and 50 eyes with Fuchs’ dystrophy. All patients received penetrating keratoplasty. The outcome measures included recurrence rate, graft rejection, graft survival rate and corneal endothelial density and other complications. Results: As compared with the other groups, TGFBI dystrophy had the highest recurrence rate (p-value < 0.0001). Fuchs’ dystrophy had the lowest graft survival rate (p-value = 0.03). Corneal endothelial cell density was lowest in Fuchs’ dystrophy 10 years postoperatively (p-value = 0.0006), but there was no significant difference in corneal endothelial cell density between the 3 groups 1 and 5 years postoperatively. There was no significant difference between the 3 groups in other complications such as graft rejection, secondary glaucoma and persistent epithelial defect (p-value = 0.809, p-value = 0.584, p-value = 0.972, respectively). Conclusions: Penetrating keratoplasty showed different long-term outcomes in treating 3 types of corneal dystrophies. The difficulty may depend on the pathogenesis of corneal dystrophies. J Korean Ophthalmol Soc 2012;53(10):1397-1402

A Simple Method for DNA Extraction from Red Algae

이유경,이홍금,Lee, Yu Gyeong,Lee, Hong Geum The Korean Society of Phycology 2003 ALGAE Vol.18 No.1