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사염화탄소-유발지방간에 대한 L-글루탐산 일나트륨의 보호작용
김형춘(Hyoung Chun Kim),이왕섭(Wang Seop Lee),전완주(Wan Jhoo Chun),최용순(Yong Soon Choi),김수희(Soo Hee Kim),이현우(Hyun Woo Lee),주왕기(Wang Kee Jhoo) 대한약학회 1992 약학회지 Vol.36 No.1
To achieve better understanding of the effects of monosodium-L-glutamate(MSG) against CCl4 fatty liver in Wister male rats, 5% MSG solution was given as drinking water and CCl4 0.1ml/kg was injected subcutaneously twice a week for four weeks. It was showed that increased hepatic phospholipid and hepatic triacylglycerol levels by CCl4 challenge were significantly decreased by additional MSG, respectively. However, MSG had no apparent effect on the elevated hepatic cholesterol level in the presence of CCl4. Histrionically, additional MSG markedly inhibited fatty degeneration, spotty necrosis, inflammation and periportal vascular proliferation manifested by CCl4. respectively. Theses results indicated that effects of MSG against CCl4 induced-fatty liver appeared to be involved with partial restoration of altered hepatic lipid composition.
사염화탄소와 Monosodium-L-Glutamate 병용투여에 의한 간조직의 환원형글루타치온 함량 및 그의 관련효소활성의 변화
김형춘(Hyoung Chun Kim),이왕섭(Wang Seop Lee),전완주(Wan Jhoo Chun),김수희(Soo Hee Kim),주왕기(Wang Kee Jhoo) 大韓藥學會 1991 약학회지 Vol.35 No.5
To explore the effect of monosodium-L-glutamate(MSG) on CCl4-damaged liver in Wister male rat, 5% MSG solution as drink water were administered after S.C. injection of 0.1 mg/kg CCl4 twice a week for 4 weeks. After last administration of MSG, heptic glutathione(GSH) dependent system was assayed. It showed that MSG increased significantly hepatic glutathione(GSH) and glutathione peroxidase(GSHpx), but decreased glutathione-S-transferase(GST) activity in normal rats. MSG increased significantly the GSHpx. and GST activities in rats with CCl4-induced liver damage. These results indicate that decrease of GSH dependent systems in CCl4 liver injury might be partially elevated by coadministration of MSG.
조강형 시멘트의 종류 및 양생방법에 따른 콘크리트의 강도특성
장준호(Chun-Ho Chang),이왕섭(Wang-Sup Lee),정용욱(Yong-Wook Jung),정연인(Youn-In Chung) 한국건설순환자원학회 2017 한국건설순환자원학회 논문집 Vol.5 No.1
본 연구는 콘크리트 2차제품의 양생시간과 양생에너지원을 감소시키기 위한 방안으로써 조강형 시멘트 사용으로 거푸집 탈형이 가능한 콘크리트의 목표 강도를 15㎫로, 양생시간을 6시간으로 설정하여 콘크리트 2차제품의 조기강도 개선을 검토하였다. 실험결과, 목표 양생시간 6시간 내 탈형 강도 15㎫의 대기양생만으로 달성가능 했던 실험체는 ACC-100에서만 가능하였으며, TRC-100과 TRC-50 실험체의 경우 증기양생을 통한 6시간, 15㎫ 값을 만족하였다. 그러나 ACC-100 실험체의 경우 초기 높은 급결성으로 인해 작업성 확보가 곤란하였으며, 작업성 개선을 위해서는 무수구연산 등의 지연제의 사용이 필요함을 알 수 있었다. 물-결합재비 변화에 따른 양상을 살펴보면 OPC-100, TRC-100, TRC-50의 경우 물-결합재비 저감에 따라 6시간 내 목표 탈형 강도 달성은 증기양생의 경우 모두 만족하는 것으로 나타났으나, 대기양생의 경우 TRC-100, TRC-50은 12시간 이내 15㎫ 달성이 가능하였다. This study selected a method which uses high early strength cement as a way to reduce the curing time and curing energy source of concrete secondary products and reviewed the improvement in the initial strength of concrete secondary products setting the target strength of the concrete capable of removing the form to 15MPa and the curing time to 6 hours. As a result of the test, the only specimen which achieved the form removal strength of 15 MPa only through atmospheric curing within the target curing time of 6hours was ACC-100, and the specimens of TRC-100 and TRC-50 satisfied the values of 6 hours and 15MPa through steam curing. However, we could see that it was difficult to secure workability in the case of the specimen of ACC-100 due to its high rapid setting property and a retarder such as anhydrous citric acid was required to be used to improve the workability. When we look into the pattern following changes in the water to binder ratio, while, in the case of stream curing, OPC-100, TRC-100, and TRC-50 were all found to satisfy achievement of the form removal strength within 6hours as the water to binder ratio decreased, in the case of atmospheric curing, TRC-100, and TRC-50 achieved 15MPa within 12hours.