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- 저자 : 이연태(Yun Tai Lee) (검색결과 58 건)
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이연태,이종훈,Lee, Yun-Tai,Lee, Chong-Hoon 대한미생물학회 1981 大韓微生物學會誌 Vol.16 No.1
Total 984 specimens were collected from sweages(130 specimens) and human rectal swabs(854 specimens) during period from October 1979 to November 1980 in Korea. Sixteen strains of salmonella were isolated from the human rectal swabs at the St. Mary's Hospital in Dae Jeon. They were confirmed into fifteen strains of S. typhi, one strain of S. paratyphi A. In other hand, fourty three strains of Shigella had been isolated from the stool specimens. They were typed as thirty four strains of Shigella flexneri, five strains of Shigella sonnei and one strain of Shigella dysenteriae. However, 16 strains of Vibrio eltor had been isolated from patients and carriers in the first epidemic areas in Chunla Namdo in September 1980. The serotype of isolated strains was determined as a Inaba which was resistant to the Mukerjee phage group IV but was susceptible to El Tor phage groupe I and II. Authors had been concluded that the strains were certain to be identified with Vibrio cholerae biotype El Tor.
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한국에 서식하는 조류와 다람쥐의 Hantavirus 감염에 대한 생태학적 연구
이연태,박철희,조규봉,송재옹,박은병,최승구,Lee, Yun-Tai,Park, Chul-Hee,Cho, Kyu-Bong,Song, Jae-Ong,Park, Eun-Byung,Choi, Sung-Gu 대한미생물학회 1996 Journal of Bacteriology and Virology Vol.26 No.1
Hantavirus is the etiologic agent of hemorrhagic fever with renal syndrome (HFRS). It has been known that the natural reservoirs of Hantavirus are not only field mice but also other animals in parts of the world. In this study, to research on the host range of Hantavirus, immunofluorescent antibody against Hantavirus was investigated in wild birds from 1991 to 1992, duck from 1991 to 1992 and squirrels (Tamias sibiricus) in 1990 in Korea. The results were as follows: 1. Of total 179 wild birds of 14 species, Emberiza elegans elegans and Passer montanus dy-bowsky were antibody positive. The positive rates were 3.92% (2 out of 51) and 1.64% (1 out of 61), respectively. 2. The antibody titers of wild birds were 1:16 and 1:64 in Emberiza elegans elegans, 1:16 in Passer montanus dybowsky. 3. The positive rate of antibody in ducks was 2.3% (3 out of 129). 4. The positive rate of antibody in squrrels was 48.10% (38 out of 79). According these results, we newly showed that passer montanus dybowsky, domestic ducks and Tamias sibiricus possessed the antibody against Hantavirus.
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A Study of the HI Antibody of the Koreans and Swine to Reovirus
이연태,이종훈,Lee, Yun-Tai,Lee, Chong-Hoon The Korea Society for Microbiology 1980 大韓微生物學會誌 Vol.15 No.1
본 연구는 한국인 및 한국 각지의 가축에 대한 reovirus 2형의 혈구응집저지항체의 분포를 알어보고저 실시된 연구이다. 사람의 피검물은 1979년 6월부터 12월까지 시내 종합병원에 래원한 신검대상자 총 614명과 한국각지의 가축(돼지) 총 877수를 대상으로 하였다. 돼지의 혈액은 1977년 6월부터 동년 9월까지 전국 25개 지역에서 채취했다. 이들에 대한 혈청을 분리하여 $-20^{\circ}C$에 보관하면서 실험하였고, 혈구응집저지시험은 Rosen(1960b, 1974)의 수기를 따랐다. 항원(Reovirus 2형)은 이호왕(1975) 교수로부터 분양받어 본 교실에서 HeLa 세포에 계대하여 혈구응집가를 확인하여 사용했다. 실험 결과는 다음과 같다. 1. 한국인 총 614명의 Reovirus 2형에 대한 10배 이상 HI항체 보유율은 73.29%로서 한국인이 높은 항체를 보유하고 있었다. 그리고 남녀비는 남자(76.47%)가 여자 (65.12%)보다 약간 높은 경향을 보였다. 2. 연령별로 본 한국인의 항체 보유율은 전 연령군에 고루게 분포되어 있었으나 41세에서 50세군이 85.71%로 약간 높았다. 3. 월별 항체보유율은 6월이 93.22%로 높았고, 10월이 47.62%로 낮았다. 4. 한편 한국의 25개 지역의 총 877수의 돼지에 분포된 항체보유율은 61.80%(542수)였다. 이를 도별로 구분한 바 서울이 83.37%로 가장 높았고, 가장 낮은 지역은 충남으로 40%였다. 5. 월별로 검출된 돼지의 항체보유율은 6월(63.21%)부터 9월(72.25%)까지 사이에 점차 증가되어 가는 경향을 보였다. 6. 사람과 돼지에 분포한 HI 항체가는 그림 2와 같이 대부분이 1:20이내에서 1:80이내에 분포하였으며 상호 차가 있었다. 이상의 실험결과를 토대로 볼때 한국자연계에는 Reovirus 2형이 광범하게 분포되어 있음을 알 수 있었으며, 한국인 및 가축(돼지)에 있어서 높은 항체가를 보유하고 있다는 사실을 새로히 알 수 있었다. The purpose of this paper is to study the incidence of humoral antibody to reovirus type 2 in the sera of the Koreans and animal(swine) at random. All the 614 of human beings and 877 of swine sera were collected during the period from June to December, 1979, from the healthy persons in the National Seoul Hospital and swine blood was collected from 25 different areas of June to 30th of September in 1977. The HI test was put with plastic plates according to the methods by Rosen(1960 a and 1974). The total 73.29% of the 614 cases in human and the 61.80% of the 877 in swine confirmed as a hemagglutination inhibition antibodies. In human the 76.47% of the 442 male cases and the 65.12% of the 172 female ones were confirmed to have humoral antibodies. The positive rate was widely shown in each age group. But the 31 to 50 old age groups showed a little higher than any other age group, which came to the 85.71% in 41-50 and the 78.72% in 31-40 old age groups. The monthly distribution of HI antibody was shown to reach the 93.22% of the 59 cases in June. This per cent was much higher than of any other distribution. Accordingly, the auther came to the conclusion that there is reovirus type 2 in all the parts of Korea and most of the Koreans have the higher rates of antibody. However, the positive rate of antibody was the 542 out of the 877 cases(61.8%) from the swine and antibodies was confirmed from the 25 different areas in Korea. The seasonal distribution of the antibody showed these high rates. In domestics animals; blood from the swine showed that distribution of HI antibodies to reoviras type 2. These antibody appears from the various areas of the province in Korea. For this reasons, reovirus was widely distributed in this country.
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상황버섯(Phellinus linteus) 자실체 분비물의 면역활성 및 항암효과
맹은호,이연태,조규봉,홍승희,Maeng, Eun-Ho,Lee, Yun-Tai,Cho, Kyu-Bong,Hong, Seung-Hee 대한면역학회 2002 Immune Network Vol.2 No.2
Background: The chemical characteristics of the exo-secretion from Phellinus linteus (referred to as exo-secretion) including the compositions of amino acids and monosaccharides were investigated. In addition, cytotoxicity of the exo-secretion on 5 tumor cell lines derived from human cancers and its antitumor activity against ascitic sarcoma-180 cells were examined. Methods: The antitumor activity of exo-secretion from Phellinus linteus was determined by measuring parameters including tumor weight, life span of mice, chemotatic activity of leukocytes, counts of immune cells, and activity of cytokines. Results: The exo-secretion from Phellinus linteus showed no direct cytotoxicity to the five tumor cell lines tested, but it had a strong antitumor activity against sarcoma-180 cells in ICR mice as measured by tumor weight and life span of mice. The exo-secretion stimulated the chemotaxis of leukocytes and production of immune cells and cytokines. Conclusion: These results suggest that the exo-secretion from Phellinus linteus do not act as a direct cytotoxic substance to cancer cells but as an immunomodulator.
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1985년 한국 각지에서 분리한 이질균속의 특성에 관한 연구
최재두,이연태,정태화,Choi, Jae-Doo,Lee, Yun-Tai,Jung, Tae-Hwoa 대한미생물학회 1987 大韓微生物學會誌 Vol.22 No.1
The result of various researches mainly in search of 194 Shigella strains, isolated by the Health Research Centers(situated in Seoul city, Inchon city, Pusan city, Kyonggi-Do, Kangwon-Do, Chungchongnam and Buk-Do, Kyongsangnam and Buk-Do, Jollanam and Buk-Do, and Jaeju-Do) in addition to those clinical laboratories of all the general hospitals situated down twon Seoul, conducted during the month of Jan. through Dec. 85, through the reisolating-activity program following its transportation into the laboratory, particularly for a complete check on its correctiveness, are as follows: 1. Isolation processes were performed with the 194 strains obtained from each placeduring the period of investigation: 164 Strains(84.5%) of Sh. flexneri, B group; 6 Strains(3.1%) of Sh. boydii, C group; 24 Strains(12.3%) of Sh. sonnei, D group, which means there's quite a lot in B group while Sh. dysenteriae, A group was not isolated at all. 2. The isolation rate of the 164, B group for subserotype was 1b, 84(51.2%) the highest one, 2(1.2%) on 3a the lowest one, 4, on C group; In D group subserotype II showed 14(58.4%) more than subserotype I. 3. The biological data on sexuality regarding the isolation-strain showed traditional particularity. But the subserotype 1b in B group 2(2.4%) showed gas-growth from glucose. In subserotype 1a, the indole-growth was 88.9% on masculine which was considerably a good one. In the test of arginine dihydrolase subserotype I among D group showed 100% masculine rate. The subserotype 6 among B group showed 92.5% masculine. In the dissolution test of manitol, all subserotypes showed 100% maculine except subserotype 1b. In the dissolutioning test of rhamnose, the subserotype I among D group showed 100% masculine which is the unusual one. 4. Interms of the area among 13 districts examined, Kangwon-Do had 41(21.1%) which is the highest one on its ratio. 5. In terms of season on the strain isolation category, 44(22.7%) is the number isolated in April which is the highest one. 6. In terms of ages, the strain isolation ratio was notably high above the ages of 60 which was 34(17.5%). Next one was 29(14.9%) which was under the ages of 4. 7. In terms of sex, female was 113 or 58.2% while male was 74 or 38.2%, which means the female had more than the male. 8. The result of the resisting capability on the usage of 12 antibiotic medication was; 100% on chloramphenicol; 94.3% on tetracycline, 82.0% on streptomycin, 76.3% on carbenicillin, 74.7% on ampicillin, in regular order. The strain source bearing multimedication resisivity against the 5 antibiotic medication is as many as 117 or 60.3%. Of which 43.3% of 1b sub serotype, B group was the best one, and thus the resistivity against the antistrain medication seems the tendency is being changed. The summing up of the above result shows the total specific strains isolated in each branch in Korea is 194, of which the main type is Sh. flexneri 84.5%. The isolating rate is almost evenly spreading, although the Kangwon-Do showed the highest rate on the above data. It also shows female is higher than male on its statistics. The tendency on age category showed both on old and infancy generations high. However, the resistant capability against antibacteria medication or vaccine was still remaining on habitual one, particularly tending towards multimedication or vaccine trend.
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