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      • 실내외 미세먼지 농도에 따른 침입계수에 관한 연구

        이신혜(Shin Hye Lee),장휴산(Hyu San Jang),주은지(Eun Ji Ju),김희강(Hee Gang Kim),강동화(Dong Hwa Kang),임동현(Dong Hyun Rim),여명석(Myoung Souk Yeo) 대한설비공학회 2019 대한설비공학회 학술발표대회논문집 Vol.2019 No.11

        The purpose of this study is to analyze the effect of outdoor particulate matter(PM) on indoors in recent high-rise residential housing unit in Korea by estimation and comparison of penetration coefficient and deposition rate. The experiment was based on natural decay test and was conducted by measuring the particulate matters after generating dusts. Penetration coefficient and deposition rate were estimated using lumped indoor particle model based on the mass conservation, and compared with the result obtained by excluding the effect of infiltration of outdoor particle. There was no significant difference in the deposition rate when the particle infiltration and penetration effect was excluded. The result suggests that recent Korean residential housing is tight and are less susceptible to external fine particle when there are no significantly high concentration of outdoor particles.

      • KCI등재후보

        급성 양측성 중심 망막 동맥 폐쇄를 동반한 시신경 척수염 1례

        이신혜(Shin Hye Lee),임진아(Gina Lim),염미선(Mi-Sun Yum),임현택(Hyun Taek Lim),고태성(Tae-Sung Ko) 대한소아신경학회 2008 대한소아신경학회지 Vol.16 No.2

        시신경 척수염은 일측성 또는 양측성 시신경염과 횡단 척수염이 동시에 또는 시간 간격을 두고 발생하는 원인미상의 탈수초성 질환이다. 소아에서는 매우 드물며, 다른 여러 탈수초성 질환들과 임상 양상만으로는 감별이 어려운 경우가 많다. 저자들은 양측 망막 동맥 폐쇄를 동반한 시신경염 소견과 지연되어 나타난 하지마비를 보인 8세 여아에서 뇌척수 자기공명영상, 뇌척수액 검사, 혈청 NMO-IgG 검사를 통해 시신경 척수염을 진단하고 유지요법으로 rituximab을 사용하여 이를 보고하는 바이다. Neuromyelitis optica(NMO) or Devic's syndrome is an uncommon clinical syndrome associating with unilateral or bilateral optic neuritis and transverse myelitis. It is rarely found in children and usually reported in adults with serious neurologic manifestations. We report a case of an 8-year-old girl with neuromyelitis optica whose first clinical manifestation was acute visual loss of both eyes. Initially the patient had been diagnosed with central retinal artery occlusion and optic neuritis by ophthalmologic examination, a brain magnetic resonance imaging, and cerebrospinal fluid findings. She was treated with intravenous methylprednisolone pulse therapy and heparinization. Then the treatments were replaced with oral prednisolone and warfarin. At the fifteenth day after the start of oral prednisolone tapering, she visited our emergency room for voiding difficulty and paresthesia on both legs. A spinal magnetic resonance imaging revealed increased signal intensity in T2-weighted images from cervical to lumbar level, and neuromyelitis optica- IgG(NMO-IgG) was detected in the patient's serum. After we diagnosed her as having neuromyelitis optica, intravenous methylprednisolone and nine courses of daily plasmapheresis were tried. However, the patient still had visual loss, pain, and sensory loss below the sixth thoracic dermatome, and we tried maintenance therapy with intravenous rituximab. We report our case with reviews of the related literatures.

      • SCOPUSKCI등재

        위식도 역류가 의심되는 소아에서 Multichannel Intraluminal Impedance-pH Metry의 유용성

        이신혜 ( Shin Hye Lee ),장주영 ( Joo Young Jang ),윤인자 ( In Ja Yoon ),김경모 ( Kyung Mo Kim ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.1

        Background/Aims: pH monitoring of the esophagus has been considered as the gold standard for the measurement of acid reflux. However, it has several limitations related to its inability to detect nonacid reflux. We conducted this study to characterize the proportion of acid and non-acid reflux events in children using pH-multichannel intraluminal impedance (MII) monitoring and to determine the correlation of the symptom index with non-acid and acid reflux events. Methods: Seventy-five children, aged from 9 days to 12 years, underwent 24 hour pH-MII monitoring at Asan Medical Center from March 2006 to June 2007. We investigated the underlying disease and main problems related to gastroesophageal reflux (GER) of the patients, the number of acid and nonacid reflux, symptom index, symptom sensitivity index in pH monitoring only and pH-MII monitoring. Results: While 2,247 reflux events were detected by MII, and only 967 reflux events were detected by pH probe alone. The percentage of acid reflux was 43% (967) and that of non-acid was 57% (1,280). The non-acid reflux increased at postprandial time (p<0.001). The symptom index increased when measured by pH-MII (31.1%) compared with those by pH probe alone (8.2%) (p=0.003). Conclusions: This study suggests that significant number of GER include non-acid reflux which cannot be detected by pH probe alone, therefore combining pH with MII monitoring is a valuable diagnostic tool for diagnosing GER in children. (Korean J Gastroenterol 2008;52:9-15)

      • KCI등재

        『風に紅葉』の性愛に關する一考察

        이신혜 ( Shin Hye Lee ) 한국일어일문학회 2015 日語日文學硏究 Vol.93 No.2

        本稿では、激變の時代を生きた中世貴族たちの性愛の斷面を調べる一つの方法として、『風に紅葉』に描かれた性愛の樣相を、人妻たちの積極的な愛情攻勢、男色、戀人の共有の三つに分類し、その特徵について考察してみた。中將に對する人妻たちの積極的な愛情攻勢では、人妻たちの密通があまりにも輕いタッチで描かれていて、密通が罪であるという意識があまり强く作用していないという点において、物語製作當時の性的本能に充實した自由な性意識をうかがうことができた。『風に紅葉』の男色は、中將と若宮との男色關係を通して權力や榮華、財産などを獲得していくという面において、物語製作當時の貴族社會に流行していた男色文化が反映されていると言えるが、二人の男性の出會いやその後の信賴關係、氣遣いなどという面においては、異性、同性を越えた眞の愛とそれを守りぬこうとする理想的な愛の形が物語に投影されたものと見ることができると思う。女性による中將共有においては、光り輝く貴公子を一人占めするよりは、仲間と共有することで、より大きな喜びと愛を分かちあえるという感覺で輕く描かれている反面、中將と若君による一品の宮共有は、分身關係にある男性二人の固い絆によるしかるべき行爲として描かれていた。なお、そのために犧牲者となり死んでしまう一品の宮の悲しみや怒りもそれなりに描かれていることもわかった。 In this story, I studied about the special feature which I classified married woman`s aggressive love offense, men`s homosexual love and sharing lover in 『Kazenimomiji』 described sexual love patterns. I could study free sexual consciousness by faithful sexual instinct in Monogatari times with the point that was lightly described about married woman`s intercourse and it was not strong criminal case. Men`s homosexual love in 『Kazenimomiji』, I think it`s reflection of homosexual love at that time society as the nephew made prosperity and fortune through homosexual love with Chujyo. However, I can guess it`s reflection of true love keeping in Monogatari as two men trust and consider each other after their meeting. In Women`s sharing love with Chujyo, it was described lightly meaning as they didn`t possess exclusively their brilliant lover but sharing then they would like to share bigger joy and love. But in the second story of Ipponnomiya sharing, I would notice that was described natural two men`s human being by the other self`s close love and it was described sacrificing died Ipponnomiya`s sorrow and anger.

      • KCI등재

        시판 젓갈에서 분리한 Clostridium perfringens의 독소 유전자 및 항균제 내성 분석

        이신혜 ( Shin-hye Lee ),박권삼 ( Kwon-sam Park ) 한국수산과학회 2023 한국수산과학회지 Vol.56 No.6

        Clostridium perfringens causes diarrhea and other diseases in humans and animals. We investigated the prevalence, toxin gene profiles, and antimicrobial resistance of C. perfringens isolated from commercial jeotgal sample. C. per-fringens was isolated from 11 of 22 commercial jeotgals. All C. perfringens strains were positive for the alpha toxin gene, but not for the beta, epsilon, iota, CPE or NetB toxin genes; therefore, all strains were identified as type A C. perfringens. However, the beta2 toxin gene was identified in 54.5% of isolates. Disk diffusion susceptibility tests showed that most isolates were resistant to kanamycin (90.9%), nalidixic acid (72.7%), oxacillin (54.5%), erythro-mycin (27.3%), ciprofloxacin (9.1%) and clindamycin (9.1%). However, all strains were susceptible to 14 other an-timicrobial including amoxicillin, ampicillin, and chloramphenicol. The average minimum inhibitory concentrations against C. perfringens of clindamycin, kanamycin, and nalidixic acid were 128.0, 128.0, and 54.0 μg/mL, respec-tively. These results provide new insight into the necessity for sanitation of commercial jeotgal, and provide evidence to help reduce the risk of contamination with antimicrobial-resistant bacteria.

      • KCI등재
      • KCI등재
      • KCI등재

        중세왕조모노가타리의 대체자(형대(形代))

        이신혜 ( Shin Hye Lee ) 한국일어일문학회 2014 日語日文學硏究 Vol.89 No.2

        본고에서는 모노가타리의 주요 테마라 할 수 있는 대체자에 주목하여 『겐지 모노가타리』와 『사고로모 모노가타리』에 등장하는 후지쓰보와 오키미, 겐 지노미야의 대체자인 무라사키노우에와 우키후네, 시키부쿄노미야 아가씨를 간단하게 살펴본 후에, 대체자가 등장하는 중세왕조모노가타리 5작품(『아키기 리』,『아사지가쓰유』,『이와데시노부』,『고이지유카시키 다이쇼』,『효부 쿄노미야 모노가타리』)에 나오는 대체자에 주목하여 각 작품에서의 남자주인 공과 대체자의 관계와 그 특징에 대하여 고찰하였다. 중세왕조모노가타리는 이루어지지 않는 사랑이라는 주제를 이어받아 전 시 대의 사고로모와 겐지노미야처럼 남자주인공은 사랑하는 사람과 좀처럼 맺어 지지 않는다. 그렇기 때문에 대체자가 등장하게 되는데 둘이서 여생을 함께 하 는 예는 3예이고, 2예는 비련으로 끝난다. 대체자와 맺어지는 해피엔딩의 경우 에도 용모가 비슷해서 총애를 받는데 지나지 않고 헤이안시대 모노가타리에 비해 대체자의 등장장면이 생략되거나 유형화되어버린 감이 있다. 본고의 고찰에 의하면, 『사고로모 모노가타리』의 영향이 강하다는 것을 알 수 있다. 즉 『아사지가쓰유』『이와데시노부』의 남자주인공은 사고로모와 마찬가지로 초출 관직이 이니노주죠이고, 사고로모와 겐지노미야처럼 남자주 인공이 사랑하는 여성에게 마음을 전하지 못하고 여성이 갑자기 사이구(?宮) 나 사이인(?院)이 되어버리는 『아사지가쓰유』『효부쿄노미야 모노가타리』 의 경우, 대체자인 여성과 비련으로 끝난다. 그리고 사고로모와 겐지노미야처럼 어릴 적에 친형제처럼 자라다가 연정을 품게 되는 경우는 『이와데시노부』와 『효부쿄노 모노가타리』이다. 다른 작품은 첫눈에 반하거나 우연히 만난다. 마지막으로 대체자 여성과의 만남은 우연한 엿보기, 행사 중 엿보기에 의한다. 우연히 엿본 대체자 여성은 사랑하는 사람과 꼭 닮은 얼굴이었다. 중세왕조모노가타리의 대체자 이야기는 기본적으로는 『사고로모 모노가타 리』의 영향 하에 있지만, 당시에 유행했던 비련둔세담인 『시노비네』의 영향 으로 비련 끝에 둔세해버리는 내용이 『아사지가쓰유』와 『효부쿄노미야 모 노가타리』에 나온다. 또한 『아키기리』는 중심인물이 없는 중세왕조모노가 타리답게 세 남자의 산조 아가씨와 그 대체자 아가씨에 대한 사랑으로 엮어져 있으며 복수의 남성이 대체자 아가씨를 사모하는 점이 특이하다. 『이와데시노 부』에서는 대체자 여성을 남자 주인공의 아들이 엿보고서 첫 눈에 반하는데 이것은 무라사키노우에에게 마음이 뺏긴 유기리의 경우와 똑같은 설정이다. 『고이지유카시키 다이쇼』에서는 다이쇼가 대체자 아가씨와 결혼한 후에 꼭 닮은 아가씨가 또다시 등장한다 In this story, I had studied that relationship between man of title role and substitute with the special feature from Medieval Dynasty Monogatari 5works which are 『Akigiri』 , 『Asajigatsuyu』 , 『Iwadeshinobu』 , 『Koijiyukashiki Taishou』 and 『Hyoubukyou Monogatari』 after I simply considered about Murasakinoue Ukihune Shikibukyounomiyano Hime who is a substitute of 『Genji Monogatari』 and 『Sagoromo Monogatari』 in the main theme. The story of substitute of Medieval Dynasty Monogatari is basically under 『Sagoromo Monogatari』`s influence but the contents of seclusion in the end of tragic was described in 『Asajigatsuyu』,『Hyoubukyou Monogatari』 by influnce of that time tendency tragic seclusion story 『Shinobine』. Also, 『Akigiri』 was consists of love between three man`s Sanjyounohime and the substitute like a Medieval Dynasty Monogatari which there is no main character and it was special that couple of men love the substitute. In the 『Iwadeshinobu』, title role of man`s son fell in love with the substitute that was the same story in case of Yugiri was loving Murasakinoue. After Taishou married with the substitute, the same character lady came out in the 『Koijiyukashiki Taishou』. It tried to distinguish with other works as above substitute of Medieval Dynasty Monogatari story became typology and simplify then various changed substitute put in each Monogatari.

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