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국내 평가 가이드 라인 제시를 위한 전동식 부항기의 특성 조사에 관한 연구
이승호,김은정,신경훈,남동우,강중원,이승덕,이혜정,이재동,김갑성,Yi, Seung-Ho,Kim, Eun-Jung,Shin, Kyung-Hoon,Nam, Dong-Woo,Kang, Jung-Won,Lee, Seung-Deok,Lee, Hye-Jung,Lee, Jae-Dong,Kim, Kap-Sung 대한침구의학회 2010 대한침구의학회지 Vol.27 No.1
Objectives : The mechanical properties of Korean electric cupping systems are studied via experimental measurements. The study aimed at establishing the fundamentals of industrialization and systemization of oriental medicine device industry, as well as improving the quality of life for many Koreans. Methods : We reviewed the studies on traditional cupping as well as modern one to fine necessary factors for electric cupping systems. To characterize the mechanical properties of Korean electric cupping systems, we measured the pressure characteristics of commercially available electric cupping system by using an automatic pressure acquisition system and a standard cup. The pumping capability was checked at 40 seconds, and the stability of the suction cup was checked at 600 seconds. We also acquired the noise level of each system in clinical setting. To check the portability of each system, we also measured its physical dimensions. We scrutinized system manuals provided by the system manufacturers. Results : It took less than 5 second to reach the pressure if the connection between the air hose and the vacuum valve of the cupping system was secure. Pressure diminished to no more than 10% for 600s for all systems. Noise levels were 55~70 dB. Increase in pressure was too fast to control for a designated vacuum level except for one product. Conclusions : The Pumping ability of the systems is impressive and reliable. Pressure retention ability of each cup is quite reliable and reproducible. Therefore, their mechanical performances were worthy of recommendation. Some of them had noise level higher than 60 dB and they were bothersome. It was also suggested that the control for low to middle pressure needed to be accomplished by the cupping system.
위성망을 이용한 파워 그리드 위기관리 시스템의 테스트베드 구현
이승호,Lee, Seung-Ho 한국전기전자학회 2011 전기전자학회논문지 Vol.15 No.1
본 논문에서는 위성망을 이용한 파워 그리드의 위기관리 시스템을 검증하기 위한 테스트베드 시스템을 제안하였다. 위기관리 시스템의 검증을 위해, 제안된 테스트베드는 위성통신의 통신품질을 기상상황에 맞추어 시뮬레이션 하였으며, 파워 그리드의 동작과 이상상황에 대한 정확한 재현을 위해 FPGA 기반의 Phase Measurement Unit(PMU) 에뮬레이터를 구현하였다. 제안된 위성통신 시뮬레이터는 전국 각 지역의 순간 강수량 및 최대 강수량 데이터를 데이터베이스화하여, 습도와 강수량에 기반을 둔 위성통신의 신뢰성을 모델링 하였으며, 인터넷을 통한 실시간 순간 강수량 데이터를 이용해 실시간 위성통신 신뢰도 맵을 구현하였다. 또한 PMU 에뮬레이터는 FPGA 를 이용한 하드웨어 기반의 에뮬레이터 구현을 통해 동작의 신뢰도를 높였다. 본 논문에서 제안한 테스트베드 시스템은 위성망을 이용한 파워 그리드 위기관리 시스템의 검증과 운영에 적용하였다. In this paper, we propose a testbed system for the crisis management system of the power grid(CMS-PG) using satellite communication network. For the verification of CMS-PG, the proposed system composed of the simulator of satellite communication network and the simulator of phase measurement unit. Proposed satellite communication simulator can evaluate the delay and the robustness of the communication according to the rainfall and the humidity of local site. And the proposed simulator can calculates the voltage stability by hardware implementation using FPGA. Using the proposed testbed system, we adapted its function of crisis management system for the conventional power grid.
이승호,허신,Lee, Seung-Ho,Heu, Shin 한국정보처리학회 1997 정보처리학회논문지 Vol.5 No.1
본 논문은 SRT 시스템에서 고정 우선순위 정책을 사용하는 쓰레드가 기존보다 더 빠른 응답시간과 반환시간을 갖도록 하기 위한 개선된 스케쥴링 모델과 알고리즘을 제시하였다. 보조 실행 큐를 첨가하여 고정 우선순위 정책을 사용하는 쓰레드의 빠른 실행 및 에이징(aging)에 사용하였다. 시뮬레이션을 통하여 기존의 방식과 비교하였 으며 그 결과, 새로 제안된 모델의 경우, 고정 우선순위 쓰레드의 반응시간과 반환시 간이 기존보다 향상되었다. This paper proposes an improved scheduling model and algorithm which threads in the fixed-priority policy have faster response time and turnaround time than existing ones in SRT system. Sub run queue is added into the system and is used for the quick execution and aging of threads in the fixed-priority policy. Using simulation two method are compared. The results shows that the new scheduling model gets threads in the fixed-priority policy to run faster than existing ones.
Antihypertensive activity of KR-31081, an orally active nonpeptide AT1 receptor antagonist
이승호,Lee, Sung-Hou The Korea Academia-Industrial cooperation Society 2009 한국산학기술학회논문지 Vol.10 No.11
The pharmacological profile of KR-31081, a newly synthesized AT1 receptor antagonist, was evaluated in pithed rats, conscious renal hypertensive rats (RHRs) and conscious furosemide-treated beagle dogs. In pithed rats, KR-31081 (i.v.) induced a non-parallel right shift in the dose-pressor response curve to angiotensin II (ID50: 0.05 mg/kg) with a dose-dependent reduction in the maximum responses; this antagonistic effect was about 40 times more potent than losartan (ID50: 1.74 mg/kg) which showed competitive antagonism. KR-31081 did not alter the responses induced by other agonists such as norepinephrine and vasopressin. In RHRs, orally given KR-31081 produced a dose-dependent and long-lasting (>24 h) antihypertensive effect with a higher potency to losartan (ED20: 0.30 and 3.36 mg/kg, respectively). In furosemide-treated dogs, orally given KR-31081 produced a dose-dependent and long-lasting (>8h) antihypertensive effect with a rapid onset of action (time to Emax: 1-1.5 h) and 20-fold greater potency than losartan (ED20: 0.41 and 8.13 mg/kg, respectively). These results suggest that KR-31081 is a potent, orally active AT1 receptor antagonist useful for the research and diagnostic tools as an added exploratory potential. 비펩타이드성 안지오텐신 수용체 길항제로 새롭게 개발된 KR-31081에 대한 생체 내 활성을 세가지 동물모델에서 검증하였다. 척수장애 동물모델에서 KR-31081은 로사탄보다 40배 이상의 경쟁적인 혈압강하 효과를 나타내었으며, 신성고혈압쥐 모델에서 KR-31081은 로사탄보다 10배 가량의 지속형 효과를 나타내었다. 또한 개실험에서 구강 투여한 KR-31081은 로사탄보다 20배 이상의 지속적인 혈압강하 효과를 나타내었다. 실험에 사용된 동물 모델 시스템에서 다른 혈관조절물질들과 상호작용을 하지 않는 것으로 나타난 KR-31081은 향후 고혈압 및 혈관질환에 대한 연구 및 진단에 활용될 수 있을 것이라고 판단된다.
큰 두위를 주소로 내원하여 헌터 증후군으로 일찍 진단된 증례 1례
이승호,박우성,이영석,유지숙,Lee, Seung Ho,Park, Woo Sung,Lee, Young Seok,Yu, Jeesuk 대한유전성대사질환학회 2014 대한유전성대사질환학회지 Vol.14 No.2
A 25-month-old boy was referred to the hospital due to large head detected on routine physical examination. At visit, dysmorphic facial appearances, including broad nose, prominent forehead, and coarse face, were noted. Nasal obstruction with nasal voice, prominent adenoids, and bilateral middle ear effusions were detected. His abdomen was distended, and liver and spleen were palpated about 3 finger and 2 finger breadths, respectively. He was operated for bilateral inguinal hernias. The motion of both elbow joints was mildly limited on supination and pronation. Urinary level of glycosaminoglycan was elevated and the enzyme activity of iduronate sulfatase in leukocytes was decreased. The mutational analysis of the gene iduronate 2-sulfatase (IDS) revealed c.263G>A (p.Arg88His) mutation. His developmental scale showed delayed development and there was cardiac valvular involvement (tricuspid regurgitation and mitral valve prolapse). After the diagnosis of Hunter syndrome, enzyme replacement therapy started on a weekly basis without progression of any clinical features. Here we report a case of early diagnosed Hunter syndrome detected by large head on routine examination. Thus, it is important to associate Hunter syndrome in the patient with large head especially, if there is the history of bilateral inguinal hernia and prominent adenoids to increase the possibility of early diagnosis and treatment.
이승호,전영미,김정기,Lee Seung-Ho,Jeon Young-Mi,Kim Jong-Ghee 대한구순구개열학회 1999 대한구순구개열학회지 Vol.2 No.1
구순구개열은 악안면의 선천기형중 발생빈도가 가장 높은 것으로 알려져 있으며,출생시부터 성장이 완료되는 시기까지 일관된 치료계획에 의한 종합적인 진료체계가 필수적이다. 구순구개열이 존재할 경우 구개부의 조기 봉합후의 반흔조직 형성으로 인한 치열궁의 협착 또는 중안모의 함몰 경향과 함께 상악 측절치의 선천적 결손 또는 기형치, 전치의 회전과 경사 등이 수반되므로 교정치료에 의한 기능적, 심미적인 치열의 회복이 필요하게 된다. 구순구개열 환자의 교정치료에 있어서 상악치열의 정상적인 배열과 구치부 반대교합의 치료를 위해 상악골 확대가 종종 필요하며, 이를 위하여 Hyrax appliance, Quad-helix 및 Fan-type expansion screw, Jointed fan type expander 등 다양한 장치가 활용될 수 있다. 심하지 않은 구순구개열 환자의 교정치료에서 상악골 확대를 위한 장치의 선택은 환자의 치열궁 형태, 연령, 구치부와 전치부의 치열궁 폭경 등 다양한 요인이 고려되어야 하며, 치료 후 악궁형태의 보정에 특별한 주의를 기울여야 할 것이다. Cleft lip and palate is the most frequent congenital facial deformity of the orofacial area. Successful management of patients with cleft lip / palate requires a multidiciplinary approach from birth to adult stage. Coordinated treatment by the cleft palate team is an essential requirement to obtain optimum treatment results. One of the negative effect of the early surgical interventions of lip and palate is a significant incidence of maxillary growth restriction that produces secondary deformities of the jaws and malocclusion that includes congenital missing of lateral incisor, malformed teeth, rotation or ectopic position of upper anterior teeth, and it has been thought due to the resistance of palatal scar tissue. In Orthodontic treatment for cleft lip / palate patients, expansion of upper dental arch or palatal suture is often needed to correct posterior and/or anterior cross bite and align upper teeth. Various appliances such as hyrax, quad-helix, fan-type expansion screw and jointed-fan type expander can be used for palatal expansion. In the orthodontic treatment of the cleft lip / palate patient, we must consider patient age and severity of palatal constriction for proper appliance selection, and must pay special attention to maintain the treatment results.
행소음전탕액(杏蘇飮煎湯液)이 가토혈장(家兎血漿) COTISOL농도(濃度) 및 $PCO_2,\;CO_2$와 GUINEA PIG의 기관지(氣管支) 평활근(平滑筋)에 미치는 영향(影響)
이승호,Lee, Sueng-Ho 대한한방내과학회 1992 大韓韓方內科學會誌 Vol.13 No.1
The following results were obtained from the observation on the change of plasma cortisol concentration in the experiment of intravenous administration of Haengsoyeum Water Extract in the rabbit. And the effects of Haengsoyeum extract on the contractile force of the isolated guinea pig trachea smooth muscle. 1. In intravenous administration the plasma cortisol concentration increased significantly about 1 hours after with a does of 0.2 ml/kg. 2. In intravenous administration the plasma cortisol concentration increased significantly about from 1 to 3 hours after with a does of 0.4 ml/kg. 3. The contractile response of the trachea smooth muscle of isolated guinea pig to histamine $10^{-4}\;M$ was significantly inhibited by Haengsoyeum extract. 4. The contractile response of the trachea smooth muscle of isolated guinea pig to acetylcholine $10^{-4}\;M$ was considerably inhibited by Haengsoyeum extract. 5. The contractile response of the trachea smooth muscle of isolated guinea pig to 5-hydroxytryptamine $10^{-4}\;M$ was inhibited by Haengsoyeum extract.