치명적인 Amiodarone 폐독성 4예

이승우,이상학,여동승,이숙영,김석찬,김관형,문화식,송정섭,박성학,정은선,Lee, Seung-Woo,Lee, Sang-Haak,Yeo, Dong-Seung,Lee, Sook-Young,Lee, Seok-Chan,Kim, Kwan-Hyoung,Moon, Hwa-Sik,Song, Jeong-Sup,Park, Sung-Hak,Jung, Eun-Sun 대한결핵및호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.53 No.6

Amiodarone 폐독성은 약제 복용력이 있는 환자에서 새로운 증상과 X-선의 변화가 있을 때 의심하여야 하며 울혈성 심부전이나 폐감염증, 폐색전증, 악성종양 등과 감별하는 것이 중요하다. 진단은 임상적, 방사선학적, 조직학적 소견을 종합하여 내릴 수 있으며 대부분의 경우에는 약제 중단을 통해서 폐독성의 호전을 기대할 수 있으나 일부에서는 호흡부전으로 진행하거나 기존의 심부정맥의 재발 등으로 인하여 사망하는 경우도 있다. 저자들은 심부정맥으로 amiodarone을 사용하던 환자에서 치명적인 폐독성이 발생한 4예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. The lungs are frequently the site of adverse drug reactions because of their higher oxygen concentration, the distinctive properties of the pulmonary circulation, and the close proximity of the alveolar epithelium to the blood. Amiodarone, an iodinated benzofuran derivative, is an effective antiarrhythmic drug commonly used for refractory tachyarrhythmia. However, it has a wide range of adverse effects, the most serious of which is lung disease. Most patients present with the insidious onset of dyspnea and a nonproductive cough, and generally recover after withdrawing the drug. We recently experienced four fatal cases of amiodarone pulmonary toxicity. Therefore, we discuss these unusual drug-induced pulmonary toxicity cases with a review of the relevant literature.

수중 음향 환경에서의 영상 전송 성능 비교분석

이승우,Lee, Seung-Woo 한국군사과학기술학회 2008 한국군사과학기술학회지 Vol.11 No.3

Underwater acoustic(UWA) communication is one of the most difficult field in terms of severe channel environments such as multipath propagation, high temporal and spatial variability of channel conditions. Therefore, it is important to model and analyze the characteristics of underwater acoustic channel such as multipath propagation, transmission loss, reverberation, and ambient noise. In this paper, UWA communication channel is modeled with a ray tracing method and applied to image transmission. Quadrature phase shift keying(QPSK) and multichannel decision feedback equalizer(DFE) are utilized as phase-coherent modulation method and equalization technique, respectively. The objective is to improve the performance of the image transmission using vertical sensor array instead of single sensor in the viewpoint of bit error rate(BER), constellation diagram, and received image quality.

지출환(枳朮丸)의 흰쥐 위(胃) 운동성(運動性)에서 정상 상태 및 위벽 국소손상 후에 대한 효능

이승우,윤상협,Lee, Seung-Woo,Yoon, Sang-Hyub 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.1

Background & Objective : Jichul-hwan(JCH) has been used for the treatment of functional dyspepsia, regarded as a gastric dysmotility disease. We investigated the effects of JCH on gastric motility and its mechanisms of action in rats. Methods : The gastric wall was injured by tracting a part of stomach body in rats. Gastric emptying was measured after administration of normal saline(NS) or JCH in normal rats and gastric wall injured rats. To evaluate the mechanism of JCH under delayed gastric emptying conditions, normal rats were treated with atropine sulfate(1mg/kg, s.c.), quinpirole HCl(0.3mg/kgg, i.p.), $NAME(N^{G}-nitro-L-arginine$ methyl ester, 75mg/kg s.c.) and cisplatin(10mg/kg, i.p.). The gastric slow waves were measured for 30 minutes before and after administration of each solution(NS, JCH). Results : JCH 110.1mg/kg improved gastric emptying for 2 hrs(p=0.014). JCH 110.1mg/kg improved gastric emptying in the gastric wall injured rats(p=0.001). Under the delayed gastric emptying, JCH 110.1mg/kg improved gastric emptying in the group treated with atropine $sulfate(1.83{\pm}0.96$ vs $8.43{\pm}8.46$, p=0.003), but aggravated it with quinpirole $HCl(4.7{\pm}2.9$ vs $1.61{\pm}2.09$, p=0.021). Administration JCH 110.1mg/kg increased EGG power in rats. Conclusions : JCH stimulates gastric motility through the cholinergic pathway, so we expect that it would be effective in the treatment of dysmotility-like functional dyspepsia with low activity of vagus nerve.

해혈(咳血)에 대(對)한 문헌적(文獻的) 고찰(考察)

이승우,Lee, Seung-Woo 대한한방내과학회 1991 大韓韓方內科學會誌 Vol.12 No.1

The following results were obtained according to these fact which is considered peviodically and bibliographically ; 1. The cause of bleeding of cough was Oegampunghan(外感風寒), Pyosaoesok(表邪外束), Chohwasangpye(燥火傷肺) in external cause, Eumhuhwadong(陰虛火動), Sinhu(腎虛), Hyulhu(血虛), Damhwajukyul(痰火積熱), Pyesuyul(肺受熱) ect. in internal cause. 2. The symptoms of bleeding of cough because of external cause was similar to generally cold symptom, because of internal cause were similar to Yeumhuhwadong(陰虛火動) and generanl Huyul(虛熱) symptom. 3. The treatment of external were Mahwangtang, Soshihotang, Sabaeksan ect. internal were Samultang, Yookmijihwangtang, Jaeumganghwatang, Gesosan ect.

사무소용 건물의 냉방시스템 운전에 관한 수치적 연구

이승우,민만기,Lee, Seung Woo,Min, Man Ki 대한설비공학회 1988 설비저널 Vol.17 No.6

An algorithm and a computer program were developed for the operational simulation of office building cooling system. Using this computer program, the following results were obtained. ${\bullet}$ There is a critical number of coil rows in AHU with which the cooling system can be operated in maximum efficiency. ${\bullet}$ Energy conservation can be achieved in an office building through TAB(Testing Adjusting and Balancing) of zone air volumes.

안와하벽재건술 후 발생한 지연성 눈뒤출혈: 증례보고

이승우,최영웅,남상현,김훈,Lee, Seung-Woo,Choi, Young-Woong,Nam, Sang-Hyun,Kim, Hoon 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.4

Purpose: Retrobulbar hemorrhage is a rare complication followed by blepharoplasty, trauma, orbital reconstruction, and so on. Most of the cases occur within 24 hours, half of them in the first 6 hours. Some authors have reported delayed retrobulbar hemorrhage after blepharoplasty and trauma within 1 day to 9 days. However, there have been few reports of delayed retrobulbar hemorrhage resulting from the complication of orbital reconstruction. Methods: A 22-year-old male underwent orbital floor reconstruction due to the orbital floor fracture. In 84 hours after the surgery, he complained sudden onset orbital pain and decreased visual acuity immediately after defecation. Intraocular pressure was unmeasurable due to the swelling at that time. Emergency computed tomography was performed. Results: Computed tomography revealed subperiosteal hematoma on inferior orbital wall extended to the apex. Emergency decompressive surgery was performed within 1 hour. After evacuation of hematoma, orbital symptom was improved and visual acuity was restored. Conclusion: Delayed retrobulbar hemorrhage is rare but vision-threatening. Therefore early diagnosis and treatment of delayed retrobulbar hemorrhage is thought to be crucial. The cause of delayed hemorrhage was not clear, however, valsalva maneuver might be the cause of hemorrhage.

저수축 시멘트 안정처리 기층의 특성분석

이승우,전범준,김종원,Lee, Seung-Woo,Jeon, Beom-Jun,Kim, Jong-Won 한국도로학회 2004 한국도로학회논문집 Vol.6 No.2

시멘트 안정처리는 우수한 강도발현, 내구성, 강성, 동상저항 등의 우수한 능력을 발휘하지만 건조수축으로 인해 표층부로의 반사균열을 발생시키는 단점을 가지고 친다. 이에 본 연구에서는 시멘트의 건조수축을 억제하여 표층부로의 반사균열을 억제할 수 있는 저수축 시멘트 안정처리기법에 대한 타당성을 연구하였다. Cement treated Soil has superior characteristics as pavement-base including strength, curability, hardness, freezing resistance. However drying shrinkage of Cement treated base has been indicated as disadvantage, since reflection crack of surface layer is induced from drying shrinkage of cement treated base. This study propriety about low-shrinkage cement treated base that can control shrinkage of cement and control reflection crack at asphalt overlay & concrete slab.

탄산화 및 저온 결정화를 통한 나트륨 농축수로부터 나트륨 화합물 합성

이승우,채수천,방준환,Lee, Seung-Woo,Chae, Soochun,Bang, Jun-Hwan 한국자원리싸이클링학회 2020 資源 리싸이클링 Vol.29 No.4

Carbonation (step I) and cryo-crystallization (crystallization at low temperature) (step II) were performed to synthesize Na compounds from sodium concentrated solution. In the step 1, the solubility and pH of carbon dioxide (95 wt.%) affecting carbonation could be changed by the variation of reaction temperature. The step II was performed at 2 ℃ after carbonation. The injection of carbon dioxide was carried out twice for the stable production and the saturated solubility of carbonate ions in solution. Firstly, we tried to inject CO₂ for controlling the solubility of CO₂ by changing the reaction temperature from 35 ℃ to 10 ℃, and the second injection was aimed at 10 ℃ for inducing nucleation of Na compound through carbonation after NaCl solution addition. In the cryo-crystallization step, the crystal growth of Na compounds could be induced by slowing the carbonation rate through reaction temperature change from 10 ℃ to 2 ℃. In this study, the effect on NaOH concentration was examined and the purity of Na compound was increased when 2M NaOH was used. In addition, the synthesized Na compounds were mostly rod-shaped and consisted of sodium carbonate or sodium carbonate with monohydrate.

인쇄 롤의 간접식 레이저 가공을 위한 코팅과 에칭 기술

이승우,김정오,강희신,Lee, Seung-Woo,Kim, Jeong-O,Kang, HeeShin 한국레이저가공학회 2013 한국레이저가공학회지 Vol.16 No.4

For mass production of electronic devices, the processing of the printing roll is one of the most important key technologies for printed electronics technology. A roll of printing process, the gravure printing that is used to print the electronic device is most often used. The indirect laser processing has been used in order to produce printing roll for gravure printing. It consists of the following processing that is coating of photo polymer or black lacquer on the surface of printing roll, pattering using a laser beam and etching process. In this study, we have carried out study on the coating and etching for $25{\mu}m$ line width on the printing roll. To do this goals, a $4{\mu}m$ coating thickness and 20% average coating thickness of the coating homogeneity of variance is performed. The factors to determine the thickness and homogeneity are a viscosity of coating solution, the liquid injection, the number of injection, feed rate, rotational speed, and the like. After the laser patterning, a line width of $25{\mu}m$ or less was confirmed to be processed through etching and the chromium plating process.

최저가낙찰제 확대 시행에 따른 파급영향

이승우,Lee, Seung-Woo 한국건설관리학회 2006 한국건설관리학회 논문집 Vol.7 No.1