메니에르병 치험 1례

이승엽,김미영,김영지,최원우,민인규,박주영,정우상,문상관,조기호,김영석,Lee, Seung-Yeop,Kim, Mi-Young,Kim, Young-Jee,Choi, Won-Woo,Min, In-Kyu,Park, Joo-Young,Jung, Woo-Sang,Moon, Sang-Kwan,Cho, Ki-Ho,Kim, Young-Suk 대한중풍순환신경학회 2008 대한중풍.순환신경학회지 Vol.9 No.1

Meniere's disease is characterized by intermittent episodes of vertigo lasting from minutes to hours, with fluctuating hearing loss, tinnitus, and aural pressure. The primary histopathological correlate is endolymphatic hydrops, but its etiology is still disputed. Several medical therapies have been offered to patients with this disease since 1961 that the first report had been given by Prosper Meniere. Some will be helpful for relieving the symptoms but there is still no absolutely effective treatment to cure the disease. One male patient with Meniere's disease was hospitalized in Kyung-Hee medical center, and we treated him with oriental medical therapies. The treatment was effective to relieve his symptoms, and they had been successfully controlled until he was discharged from hospital. The result suggests that the oriental medical therapy is safe and helpful to patients with Meniere's disease, so we reported this case.

토착미생물의 생지화학적 활동에 의한 지하수의 산화/환원전위 변화 특성

이승엽,노열,정종태,Lee, Seung Yeop,Roh, Yul,Jeong, Jong Tae 대한자원환경지질학회 2014 자원환경지질 Vol.47 No.1

중금속류나 방사성 물질로 오염된 지하수를 원위치에서 처리(정화 혹은 고정화)하고자 할 때, 반드시 고려해야 할 지화학적 요소 중의 하나는 지하수의 산화/환원전위 값이다. 우리는 생지화학적 작용에 의한 현장 지하수의 산화/환원전위 변화 특성을 알아보기 위해 실험실 조건에서 한국원자력연구원의 심부지하수를 대상으로 전자공여체(젖산), 전자수용체(황산염) 및 토착미생물을 주입하여 시간별로 산화/환원전위 변화를 관찰하였다. 질소가스-충전 글로브박스에 있는 순수 지하수는 시간이 경과함에 따라 미약한 Eh 상승(약산화)이 있었다. 하지만, 젖산, 황산염 혹은 미생물이 주입된 지하수 대부분의 Eh는 감소(환원)하는 특성을 보여주었다. 특히, 국내 토착 황산염환원미생물인 '바쿨라텀'이 주입되었을 때, 지하수의 Eh가 -500 mV 근처까지 감소하여 강환원성 지하수로 바뀌었다. 이처럼 일반 금속환원박테리아에 비해 황산염환원박테리아의 지하수 환원화 능력이 매우 우수함에도 불구하고, 용존 황산철을 필요로 하였고 최종적으로 황화광물(예; 맥키나와이트)이 생성되면서 추후 반응에 관한 예측을 어렵게 하였다. 결과적으로, 미생물 외에도 미량의 영양물질 주입 여하에 따라 지하수의 산화/환원전위가 크게 달라졌으며, 이는 산화/환원전위의 영향을 받는 용존 오염 물질의 산화수, 용해도 및 수착 등의 특성들이 생물자극법에 의해 바뀌거나 조절될 수 있음을 의미한다. As we are trying to in-situ treat (purify or immobilize) heavy metals or radionuclides in groundwater, one of the geochemical factors to be necessarily considered is the value of oxidation/reduction potential (ORP) of the groundwater. A biogeochemical impact on the characteristic ORP change of groundwater taken from the KAERI underground was observed as a function of time by adding electron-donor (lactate), electron-acceptor (sulfate), and indigenous bacteria in a laboratory condition. There was a slight increase of Eh (slow oxidation) of the pure groundwater with time under a $N_2$-filled glove-box. However, most of groundwaters that contained lactate, sulfate or bacteria showed Eh decrease (reduction) characteristics. In particular, when 'Baculatum', a local indigenous sulfate-reducing bacterium, was injected into the KAERI groundwater, it turned to become a highly-reduced one having a decreased Eh to around -500 mV. Although the sulfate-reducing bacterium thus has much greater ability to reduce groundwater than other metal-reducing bacteria, it surely necessitated some dissolved ferrous-sulfate and finally generated sulfide minerals (e.g., mackinawite), which made a prediction for subsequent reactions difficult. As a result, the ORP of groundwater was largely affected even by a slight injection of nutrient without bacteria, indicating that oxidation state, solubility and sorption characteristics of dissolved contaminants, which are affected by the ORP, could be changed and controlled through in-situ biostimulation method.

소양인 형방도적산과 양격산화탕의 항 스트레스효과에 관한 실험적 연구

이승엽,최애련,하진호,이정환,김판준,구덕모,Lee, Seung-Yeop,Choi, Ae-Ryun,Ha, Jin-Ho,Lee, Jung-Hwan,Kim, Pan-Joon,Goo, Deok-Mo 사상체질의학회 2008 사상체질의학회지 Vol.20 No.3

1. Objective This study was done to identify the anti-stress effect of Hyeongbangdojeok-san (HDS), Yanggyeoksanhwa-tang(YST) in Soyangin. 2. Methods Experimental animals were composed of YST, HDS+stress groups which were administered each by 200mg/kg, 400mg/kg and the Saline+stress group. On the 1st day, making the rats forced swim and on the 2nd day, applying Forced swimming test to the rats. After FST, the levels of Corticosterone in the blood were measured. For the study of learning retardation, memory ability and anxiety reaction, experimental animals were composed of YST, HDS+restraint stress groups which were administered each by 400mg/kg, no stress group and the Saline+restraint stress group. Restraint stress were applied 2 hours a day for 3 weeks. On the last day of the 3rd week, Elevated Plus Maze(EPM) was applied to the groups and Morris Water Maze(MWM) was applied to the groups for 7 days. 3. Results 1. As the results of measuring FST which reflects depression, the YST+stress group and the HDS+stress group showed significant effect in comparison with the Saline+stress group. The levels of Corticosterone in the blood were decreased only in the 400mg/kg YST+stress group. 2. As the results of measuring how long EPM which reflects anxiety reaction stayed in the open arm, there was the trend which can suppress anxiety reaction in the HDS+restraint stress group bur no statistical significance. But there was any suppression of anxiety reaction in the YST+restraint stress group. 3. According to the result of MWM, the saline+restraint stress group showed the learning retardation which means increased time arriving at goal compared to the normal group at the second and third day of measurement. On the contrary, a learning retardation was significantly decreased in the YST+restraint stress group at the third day of measurement. 4. Among the Probe trial test a memory loss occurred in the saline+restraint stress group, but memory ability was significantly increased in the YST+restraint stress group. 4. Conclusion: As the results above, Soyangin Yanggyeoksanhwa-tang has significant influence to the antidepression effect, the learning retardation, the anxiety reaction and also in the Hormone level. Hyeongbangdojeok-san has significant influence to the antidepression effect, in the Hormone level, bur not to the learning retardation and anxiety reaction. prefer to drink cold water, and who are suffering from chronic gastritis.

유향-가중 그래프 이론의 상수도관망에 적용

이승엽,정동휘,Lee, Seung-Yeop,Jeong, Dong-Hwi 한국수자원학회 2018 물과 미래(한국수자원학회지) Vol.51 No.6

한국원자력연구소 지하처분연구시설(KURT)의 암석 풍화 및 지화학적 특성

이승엽,백민훈,조원진,한필수,Lee, Seung-Yeop,Baik, Min-Hoon,Cho, Won-Jin,Hahn, Pil-Soo 한국방사성폐기물학회 2006 방사성폐기물학회지 Vol.4 No.4

A basic research was conducted on the mineral weathering and geochemical characteristics in the KURT (KAERI Underground Research Tunnel), which was recently constructed at a site in KAERI. Some rock samples exposed during the KURT construction were examined using a microscope and chemical analysis for some micro-changes of the rocks caused by the chemical weathering. The weathered granite has some small and fine cracks around the rock-forming minerals. In particular, there are a characteristic weathering of feldspar mineral and a preferential leaching of Ca component from the mineral dissolution. In addition, by the dissolution of biotite containing $Fe^{2+}$ component there were iron-oxides precipitates as secondary products into the microcracks of around minerals. The results also show that the micro-cracks initiated from the mineral interior are extended and connected into the larger cracks along the grain boundary with the progress of the weathering. Thus, it is considered that some chemicals dissolved from the fresh rock would be involved in the formation of secondary minerals and migrate interacting with them.

한방병원에 내원한 파킨슨 증후군 환자 증례군 보고

이승엽,김미영,김영지,최원우,민인규,선종주,홍진우,나병조,정우상,문상관,조기호,김영석,Lee, Seung-yeop,Kim, Mi-young,Kim, Young-jee,Choi, Won-woo,Min, In-kyu,Sun, Jong-joo,Hong, Jin-woo,Na, Byong-jo,Jung, Woo-sang,Moon, Sang-kwan,Cho, Ki-h 대한중풍순환신경학회 2007 대한중풍.순환신경학회지 Vol.8 No.1

Objective : To report cases of patients with Parkinson's syndrome. Design : Case-series Patients and methods : 35 of patients with Parkinson's syndrome who visited Department of Cardiovascular and Neurologic Diseases of Kyunghee Oriental Medical Center were treated by acupuncture and herbal medicine from May until December 2007. 35 patients were participated in this study. 21 patients were dropped out during the trial, and we evaluated symptom progress of 14 patients by using several questionnaires such as Unified Parkinson's Disease Rating Scale(UPDRS), modified Hoehn & Yahr stage (H&Y stage) and Schwab & England ADL scale(S&E ADL scale). Results : The whole group consists of 14 male patients and 21 female patients. Mean±SD age range is 64.5±8.4. There were no significant differences of the demographic and clinical characteristics between the case group and drop-out group. The mean±SD medical treatment period of the Case group were 8.4±6.3weeks, the mean±SD of the total score in first medical treatment UPDRS section 1~3 were 29.6±11.0, the mean±SD of the final score were 27.1±12.6, all of which showed significant improvement(p=0.007). There were no significant changes on the H&Y stage and S&E ADL scale. Conclusion : Patients with Parkinson's syndrome who visited Department of Cardiovascular and Neurologic diseases of Kyunghee Oriental Medical Center had a tendency of showing improvement in clinical symptoms.

스와넬라균(Shewanella p.)에 의한 용존우라늄 제거 특성 및 방사성폐기물 처분에의 응용

이승엽,백민훈,송준규,Lee, Seung-Yeop,Baik, Min-Hoon,Song, Jun-Kyu 대한자원환경지질학회 2009 자원환경지질 Vol.42 No.5

물속에 우라닐이온(${UO_2}^{2+}$) 형태로 존재하는 산화우라늄을 철환원세균인 스와넬라균(Shewanella p.)을 이용하여 제거하는 실험을 수행하였다. 용액상의 우라늄 초기농도는 $50{\mu}M$ 이었으며 미생물과의 반응에 의해 점차 그 농도가 감소하였고, 약 2주 후에 거의 대부분의 우라늄이 제거되었다. 우라늄이 제거된 기작은 대부분 미생물 표면에 대한 흡착, 침전 및 광물화에 의한 것이었다. 투과전자현미경으로 관찰한 결과로는 미생물 표면에 흡착되어 점차 결정화되어가는 우라늄이 큰 광물로 성장하고 여러 미생물개체 및 유기분비물과의 결합을 통해 그 크기가 수 ${\mu}m$ 이상으로 커져가는 것을 확인하였다. 이러한 미생물에 의한 우라늄 광물의 성장 및 결합은 방사성폐기물처분장의 우라늄 거동에 큰 영향을 끼칠 수 있으며, 특별히 본 실험에서 관찰한 생지화학적인 금속환원미생물의 역할에 의해 지하 우라늄의 이동이 상당히 지연되는 효과를 거둘 수 있을 것으로 사료된다. An experimental removal of dissolved uranium (U) exsiting as uranyl ion (${UO_2}^{2+}$) was carried out using Shewanella p., iron-reducing bacterium. By the microbial reductive reaction, initial U concentration ($50{\mu}M$) was constantly decreased, and most U were removed from solution after 2 weeks. Major mechanism that U was removed from the solution was adsorption, precipitation and mineralization on the microbe surface. Under the transmission electron microscopy, the U adsorbed on the microbe was observed as being crystallized and eventually enlarged to several ${\mu}m$ sizes of minerals by combining with individual microbes and organic exudates. It seems that such U growth and mineralization on the microbial surface could affect the U behavior in a radioactive waste disposal site. Thus, the biogechemical reaction of metal-reducing bacteria observed in this experiment could give an affirmative measure that the microbial activity may retard U movement in subsurface environment.

온라인 동영상 서비스와 기존 매체 간의 경쟁관계에 관한 적소분석

이승엽(Seung Yeop Lee),이상우(Sang Woo Lee) SBS 2014 미디어경제와 문화 Vol.12 No.3

최근 인터넷망을 통해 동영상 콘텐츠를 제공하는 서비스가 다양한 사업자들에 의해 시도되고 있다. 미국에서는 이러한 온라인 동영상 서비스로 인해 기존의 유료방송 가입자가 줄어들고 있다는 주장이 제기되기도 하였다. 본 연구에서는 최근 확산되고 있는 온라인 동영상 서비스가 지상파TV, 케이블TV, IPTV, 위성방송, DMB, 라디오, SNS, 게임, 신문, 도서 등 기존 매체와 어떠한 경쟁관계를 형성하는지 적소이론을 통해 분석하였다. 분석 결과 온라인 동영상 서비스는 지상파TV, 케이블TV, IPTV, 위성방송, 게임 등의 매체와 경쟁관계를 형성하였으나 이들 매체에 대해 경쟁적으로는 상당히 열위에 있는 것으로 나타났다. 특히 케이블TV에 대해서는 경쟁적 열위가 매우 심하였다. 그 이유는 이용자들이 온라인 동영상 서비스 이용시간의 대부분을 집에서 이용하고 있으며, 집에서는 전통적으로 지상파TV나 유료방송과 같은 텔레비전의 경쟁적 우위가 강하기 때문이었다. Lately many service providers have been attempting to provide video contents via the Internet. And some reports in the United States showed that the number of pay TV subscribers was decreasing while the number of online video users was increasing. Based on the niche theory, this study analyzed the competition between online video service and traditional media, such as terrestrial TV, cable TV, IPTV, direct broadcast satellite (DBS), and so on. The results showed that there was a high degree of competition between online video service and some media, such as terrestrial TV, cable TV, IPTV, DBS and games. However, online video service had competitive inferiority compared to these media. In particular, it had extreme competitive inferiority compared to cable TV. This is because users tend to watch the online video service mostly at home, where traditional pay TV, such as cable TV, has had strong competitive superiority.

기획논문 : 온라인 동영상 서비스의 유료방송에 대한 대체현상 연구

이승엽 ( Seung Yeop Lee ),이상우 ( Sang Woo Lee ) 정보통신정책학회 2013 정보통신정책연구 Vol.20 No.4

최근 다양한 형태의 온라인 동영상 서비스가 출시되고, 그 이용도 증가하면서 이서비스가 유료방송과 같은 기존 미디어에 미치는 영향에 대한 관심이 높아지고 있다. 아직까지 우리나라에서는 온라인 동영상 서비스의 성공사례를 찾아보기 어려우나 미국 등 일부 해외 주요국에서는 많은 이용자를 확보한 온라인 동영상 서비스가 등장하고 있으며, 이들이 유료방송시장에 미치는 영향에 대해 주목하고 있다. 본 연구는 온라인 동영상 서비스와 유료방송 간의 경쟁관계를 이용자들의 온라인동영상 서비스 이용시간이 유료방송 이용시간을 대체하는 현상을 통해 밝혀보고자 한다. 즉 이용자들이 온라인 동영상 서비스를 이용한 이후 유료방송 이용시간이 감소되었는지 여부와, 감소되었다면 그 정도가 온라인 동영상 서비스 유료서비스와 무료서비스 사이에 어떠한 차이가 있는지 분석하였다. 그리고 온라인 동영상서비스의 콘텐츠 장르 중 유료방송 이용시간이 감소하는데 영향을 미친 콘텐츠 장르에 대해서 알아보았다. 설문조사를 통해 분석한 결과, 온라인 동영상 서비스 이용시간이 길수록 유료방송 이용시간이 더 많이 감소되었다. 또한 온라인 동영상유료서비스 이용이 무료서비스 이용보다 유료방송 이용시간을 더 감소시켰다. 그리고 온라인 동영상 서비스의 콘텐츠 장르 중에는 온라인 동영상 유료서비스로 제공되는 코미디, 뉴스, 드라마가 유료방송 이용시간을 감소시켰다. Access to video contents through the internet is increasing due to the deployment of both high-capacity internet infrastructure and advanced internet-connected devices. The growth of internet video usage has led to the development of online video service market over the past few years. FCC`s recent report shows that the usage of online video service affects the usage pattern of other types of video services in the United States. This paper examines the relationship between online video viewing and traditional pay TV viewing. The data for this study was collected from 193 public institution employees in the field of ICT and 28 students at graduate school of mass communication. The result shows that online video viewing causes reduction to the amount of time that was previously spent on traditional pay TV viewing. Also, pay online video users show higher displacement effect for their pay TV than free online video users. In addition, this study shows that there are certain genres of online video content that reduce the amount of time spent on pay TV. In the case of comedies, news, and dramas provided by pay online video services, the amount of time spent on pay TV was reduced, while other genres were not significantly related to the usage amount of traditional pay TV. Although respondents in this study were not representative of general population, the video usage pattern of these respondents, including early adopters and heavy users of internet-based services, may provide us preview point for a future trend for online video usage.

초고층 건축물에서 아웃리거와 벨트트러스 시스템의 구조적 거동 및 효율성

이승엽(Lee, Seung Yeop),우태욱(Woo, Tae Uk),김대경(Kim, Dae Kyung) 대한건축학회 2022 대한건축학회 학술발표대회 논문집 Vol.42 No.1