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이순애(Lee, Sun Ae),손수경(Sohn, Sue Kyung) 대한종양간호학회 2013 Asian Oncology Nursing Vol.13 No.4
Purpose: This study was to describe the relationship between optimism and post-traumatic stress disorder (PTSD) in breast cancer patients. Methods: The data were collected by self-administered questionnaires from March 5 to April 24, 2012. The participants included 204 breast cancer patients at K university hospital in D city. The utilized measurements were Life Orientation Test-revised (LOT-R) and Impact of Event Scale (IES). Results: The mean scores of optimism and PTSD were 21.61±3.54 and 30.18±10.43, respectively. There were significant differences in the score of optimism by monthly income, engaging in a hobby, perceived level of stress management, need to manage stress, and people thought to be helpful in stress management. There were significant differences in the score of PTSD by engaging in a hobby, recurrence of cancer, the number of hospitalization, perceived level of stress management, need to manage stress, and people thought to be helpful in stress management. There was a negative correlation between optimism and PTSD. Conclusion: To relieve post-traumatic stress in breast cancer patients, nurses should provide ongoing psychological stress assessment from the beginning of the diagnostic stage and offer proper nursing intervention to improve optimism in dealing with their stress.
대황고(大黃膏)의 메티실린 내성 황색 포도상구균에 대한 항균활성
이순애 ( Sun-ae Lee ),공룡 ( Ryong Kong ),강옥화 ( Ok-hua Kang ),서윤수 ( Yun-soo Seo ),주전 ( Tian Zhou ),김상아 ( Sang-a Kim ),송옥희 ( Ok-hee Song ),김민철 ( Min-chul Kim ),한형선 ( Hyoung-sun Han ),최지나 ( Ji-na Choi ),이영섭 대한본초학회 2017 大韓本草學會誌 Vol.32 No.2
Objectives : Infectious diseases by Methicillin-Resistant Staphylococcus aureus (MRSA) are a growing problem worldwide. Characteristic of MRSA is endlessly mutation to resist antibiotics. Daehwanggo (DHG) is one of the oriental medicine prescriptions contained in Principles and Practice of Eastern Medicine. Daehwanggo was mainly used for external preparation from old times. The purpose of this study is to confirm possibility as supplementary drug of DHG about antibiotics through observation of synergy effect between DHG and commercial antibiotics and to observe restriction on growth of MRSA on any pathway through observation of mechanism. Methods : The minimum inhibitory concentration (MIC) of DHG against MRSA is 500 ~ 2000 ㎍/㎖ by broth dilution method. In the checkerboard method, the combinations of DHG with antibiotics has partial synergistic effect or synergy effect and DHG markedly reduced the MICs of the antibiotics oxacillin (OX), gentamicin (GT) against MRSA. In the inhibition of resistance mechanism of DHG against MRSA, the expression of resistance gene and protein about β-lactam antibiotic was reduced. Also, we observed the effect of DHG about cell membrane permeability against MRSA, and confirmed that DHG suppressed growth of strains by increasing cell membrane permeability. Results : Basis on the result, we speculate that DHG increase antibacterial activity of antibiotics against MRSA by changing the structure of cell wall of MRSA. Conclusions : These data suggest that Daehwanggo possesses possibility as supplementary drug about antibiotics against MRSA.
유경선 ( Kyoung Sun You ),신정규 ( Jeong Gyu Shin ),최원준 ( Won Jun Choi ),이순애 ( Soon Ae Lee ),이종학 ( Jong Hak Lee ),백원영 ( Won Young Paik ) 대한주산의학회 2002 Perinatology Vol.13 No.3
30세 이하 여성에서의 유병률은 위암 발생률 중 단 0.4~0.5%를 차지하며 임신과 동반된 경우는 발생빈도가 매우 드물며 비특이적인 증상으로 인하여 진행된 병기에서 진단됨으로 매우 불량한 예후를 보인다. 임신시 동반된 위암의 연구자료는 부족한 형편이며 위암의 발병률이 비교적 높은 일본에서는 1916년 이후 1988년까지 103례에 국한된 보고가 있으나 국내에서는 임신과 동반된 위암의 역학 및 그 임상례의 보고는 찾기 어렵다. 저자들은 임신 전 기간을 통하여 오심, 구토, 속쓰림을 호소하던 산모가 임신 말기에 위천공을 동반한 태아 절박 가사로 응급 제왕 절개술을 시행, 수술시 태반 조기박리 및 임상병기 4기의 위암을 진단하였기에 문헌 고찰과 함께 증례 보고하는 바이다. The coincidence of stomach cancer and pregnancy is a rare event. Most of the cases are diagnosed in advanced stage either because the patient`s symptoms are attributed to her pregnancy or because of a reluctance to pursue diagnostic studies during pregnancy. So, the prognosis for a pregnant woman with stomach cancer is very poor. We experienced a case of perforated stomach cancer with placental abruption during pregnancy and report with a brief review of literature.
Shih-tzu견에서 초음파 검사에 의한 분만일 예시표 확립
김방실,고진성,이순애,조양택,김재풍,오기석,김종택,박인철,김영홍,손창호,Kim, Bang-sil,Ko, Jin-sung,Lee, Sun-ae,Cho, Yang-tak,Kim, Jae-pung,Oh, Ki-seok,Kim, Jong-taek,Park, In-chul,Kim, Young-hong,Son, Chang-ho 대한수의학회 2004 大韓獸醫學會誌 Vol.44 No.2
To establish a prediction table of parturition day real-time B-mode ultrasonographic examinations were performed in 12 pregnant Shih-tzu bitches. Measurement of inner chorionic cavity diameter and fetal head diameter was performed from 15 days of gestation to parturition. These were converted retrospectively based on the day of parturition (Day 0). The data of inner chorionic cavity diameter obtained from Day -44 to Day -25 and fetal head diameter obtained from Day -25 to Day -1 were used to compile a prediction table of parturition day. The 22 pregnant Shih-tzu with unknown mating time were examined to assess an accuracy of the table established in this study. And these results were applied to the prediction of parturition day and compared to actual parturition day. Parturition day prediction based on the inner chorionic cavity diameter and fetal head diameter was 100% accurate within ${\pm}2$ days. In addition, the accuracy for parturition day within 0, ${\pm}1$, and ${\pm}2$ days interval using the prediction table of parturition day were 68, 82, and 100%, respectively. Therefore, the prediction table of parturition day seems to be a useful tool for the prediction of parturition day in practice.
유방암 환자에서 타목시펜 사용 후 발생한 자궁내막 폴립, 난소 낭종 및 지방간
이종학 ( Jong Hak Lee ),유경선 ( Kyoung Sun You ),이정희 ( Jeong Hee Lee ),신정규 ( Jeong Gyu Shin ),이순애 ( Soon Ae Lee ),백원영 ( Won Young Paik ) 대한폐경학회 2003 대한폐경학회지 Vol.9 No.1
Tamoxifen, a nonsteroidal hormone that acts as antiestrogen in breast tissue, is used among women of all ages for treatment of all stages of breast cancer and reduces the risk of subsequent contralateral breast cancer as well as breast cancer recurrences and mortality. However, there is mounting evidence that tamoxifen may affect other hormone sensitive organs, including uterus and ovaries. An increased risk of gynecologic diseases; endometrial polyps, endometrial hyperplasia, endometrial adenocarcinoma and ovarian cysts have been reported in tamoxifen treated women. We have met a case of endometrial polyp, ovarian cysts, and fatty liver which were associated with tamoxifen use in breast cancer patient and report with the brief review of literatures.
지유 (Sanguisorbae officinalis L.)의 항암 및 항균효과
안봉전 ( An Bong Jeon ),이순애 ( Lee Sun Ae ),손준호 ( Son Jun Ho ),곽재훈 ( Gwag Jae Hun ),박정미 ( Park Jeong Mi ),이진영 ( Lee Jin Yeong ) 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.1
The cytotoxic and antibacterial activities of Sanguisorbae officinalis L., which is blown as a major tannin source, were investigated to check the possible use of natural nutraceutics or cosmetics. The S. officinalis inhibited cancer cell growth in a dose-dependant manner. Also, the clear zone against various bacteria such as Staphylococcus aureus, S. epidermidis, E. coli were evident at 0.5 and 1 ㎎/dusc. When the concentrations were 500 and 1,000 ppm. growth of all aerobic bacteria increased at early stage but decrease afterward. The results indicated that S. officinalis had the anti-skin cancer activity as well as antibacterial activity against skin-related bacteria.
30대 젊은 여성에서 발생한 자궁내막암 6예의 임상 병리학적 고찰
신수경 ( Sin Su Gyeong ),이풍구 ( Lee Pung Gu ),신정규 ( Sin Jeong Gyu ),최원준 ( Choe Won Jun ),이순애 ( Lee Sun Ae ),이종학 ( Lee Jong Hag ),백원영 ( Baeg Won Yeong ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.10
목적 : 본 연구는 40세 이하의 젊은 여성에서 발생한 자궁내막암의 임상적인 특성, 조직 병리학적 소견, 치료 및 예후 등을 알아보기 위하여 본원에서 진단받은 젊은 자궁내막암 환자를 대상으로 임상적 고찰을 시행하였다. 연구 방법 : 1999년 1월부터 2002년 12월까지 경상대학교병원 산부인과에서 진단 및 치료를 받은 총 45예의 자궁내막암 환자 중 30대 젊은 여성 6예를 대상으로 하였으며 환자의 임상 병리학적 특성과 치료 및 예후를 알아보기 위하여 Objective : This study was performed to evaluate the clinical characteristics, histopathology and prognosis of endometrial cancer under 40 years of age. Methods : This retrospective study was based on medical records including pathologic reports of 6 wome
유방암 환자에서 Toremifene 사용 후 발생한 자궁내막암
백원영 ( Baeg Won Yeong ),이정희 ( Lee Jeong Hui ),신정규 ( Sin Jeong Gyu ),최원준 ( Choe Won Jun ),이순애 ( Lee Sun Ae ),이종학 ( Lee Jong Hag ) 대한폐경학회 2003 대한폐경학회지 Vol.9 No.2
Tamoxifen, a nonsteroidal hormone that acts as antiestrogen in breast tissue, is used among women of all ages for treatment of all stages of breast cancer. Tamoxifen reduces the risk of subsequent contralateral breast cancer as well as breast cancer recurrences and mortality. Toremifene is another antiestrogen, less uterotrophic agent which has been proven to be effective in the treatment of breast cancer. The use of both tamoxifen and toremifene has been linked to the risk of endometrial polyps, endometrial hyperplasia and tamoxifen may increase the risk of endometrial cancer. However due to the rare use of toremifene up to the mid-1990s, the risk assessment concerning endometrial cancer was inconclusive. We experienced a case of endomerial cancer associated with toremifene use in breast cancer patient and report with the brief review of literatures.