Servo 구동 장력 조절 장치 최적화 설계에 관한 연구

이상화,정혜천,이혁진,이재원,전두환,Lee, Sang-Hwa,Jeong, Hye-Cheun,Lee, Huck-Jin,Lee, Jeh-Won,Chun, Du-Hwan 한국섬유공학회 2008 한국섬유공학회지 Vol.45 No.3

Tension control of fiber manufacturing process system is usually achieved by using loadcell and powder clutch, which require additional mounting space, reduce the reliability in harsh environments and increase the cost of the system. The physical properties of textile fabrics are very sensitive to several factors(temperature, humidity, radius change of warp beam etc.)which result in tension change. In this paper, the optimal tension control of servo motor driver system using PI control algorithm is presented. The proposed tension algorithm is robust to disturbance and tension variation. First the modeling and dynamic behaviors of the tension system is described. Then validity and usefulness of the proposed algorithm and mechanical system are thoroughly verified through numerical simulation and actual conditions.

Increased Protein of the Secretory Leukocyte Pretense Inhibitor (SLPI) and the Expression of Growth Factors in NIH3T3 Cells by LPS Stimulation

이상화,최백동,정순정,장현선,김병옥,임도선,박주철,왕관림,정문진,Lee, Sang-Hwa,Choi, Baik-Dong,Jeong, Soon-Jeong,Jang, Hyun-Seon,Kim, Byung-Ock,Lim, Do-Seon,Park, Joo-Cheol,Wang, Guan-Lin,Jeong, Moon-Jin Korean Society of Electron Microscopy 2006 Applied microscopy Vol.36 No.3

분비백혈구단백분해효소억제제 (SLPI)는 염증 부위에서 중성구 엘라스타제에 의한 손상 작용에 대해 조직을 보호하는 역할을 한다. SLPI의 새로운 기능에 대한 연구들은 단백질분해효소억제제 역할보다는 선천적 면역반응 작용에 주로 관여 할 것임을 보고하였다. 따라서 본 연구는 섬유모세포 세포주(NIH3T3)에서 박테리아성지질다당류(LPS)자극에 의한 SLPI의 기능을 확인하기 위하여 LPS처리에 따른 여러 성장 인자들과 비교하여 SLPI의 발현을 알아보았다. 역전사효소 중합반응(RT-PCR)과 면역학적 단백질 검출법 (Western blot)은 LPS 처리 후 SLPI와 몇몇 성장 인자들(VEGF, bFGF, PDGF)의 mRNA와 단백질의 검출을 위해 수행하였다. NIH3T3 세포주를 mL당 100ng의 LPS에 각각 30, 60, 90분, 24, 48시간 동안 노출시켰다. RT-PCR 결과 SLPI와 VEGF mRNA는 LPS처리와는 상관없이 강한 발현 양상을 보였다. bFGF mRNA는 대조군과 같이 약하게 발현하였고, PDGF mRNA는 LPS 노출 시간에 따라 점진적으로 증가하는 양상을 나타냈다. 그러나 세포질 용해액과 세포 배양액에서 SLPI단백질의 수준은 LPS처리에 의해 증가하였다. 또한 광학 현미경 관찰과 전자 현미경 관찰은 LPS가 NIH3T3세포주의 형태학적인 변화를 유발시킴을 증명하였다. 따라서 LPS는 NIH3T3세포에서 SLPI의 발현 증가를 조절하며, 분비된 SLPI는 세포분열과 이동을 자극할 것이라는 결론을 얻었다. SLPI가 세포분열과 세포이동에 어떻게 관여하는지는 아직까지 규명되지 않은 실정이므로-추후에 SLPI단백질이나 유전자 도입을 통하여 세포 이동에 관련된 실험이 진행되어야 할 것이다. Secretory leukocyte protease inhibitor (SLPI) involves tissue protection against the destructive action of neutrophil elastase at the site of inflammation. Several studies on new functions of SLPI have demonstrated that SLPI may play a primary role in innate immunity than protease inhibitor, To identify the function of SLPI by lipopolysaccharide (LPS) stimulation in the embryonic fibroblast (NIH3T3) cells. we studied the expression of SLPI compared to other growth factors involving the LPS treatment. To address this, we performed the reverse transcriptase polymerase chain reaction (RT-PCR) and Western blots for the detection of mRNA and protein expression of the SLPI and some growth factors such as VEGF. bFGF, and PDGF-BB after LPS stimulation. NIH3T3 cells were exposed 100 ng/mL Escherichia coli LPS for 30min, 60min, 90min, 24h, and 48h, respectively. The result of RT-PCR showed that SLPI and VEGF mRNA was expressed strongly in NIH3T3 without related to LPS stimulation. mRNA of bFGF was weakly expressed such as the expression of the control. PDGF mRNA expression gradually increased follows at time course. However, SLPI protein level was increased in lysates and culture medium by LPS stimulation. Phase contrast microscopic and scanning electron microscopic observation showed that the increased cell number and cytoplasmic enlargement of the NIH3T3 cells. Therefore, it suggests that the LPS upregulates SLPI expression in NIH3T3 cells. Moreover, secreted SLPI may stimulate cell proliferation and migration.

시험연구의 영역을 확대해야

이상화,Lee, Sang-Hwa 한국화재보험협회 1991 防災와 保險 Vol.49 No.-

보험설계에 도움줄 수 있는 위험관리 기대

이상화,Lee, Sang-Hwa 한국화재보험협회 1992 防災와 保險 Vol.53 No.-

약인성 급성 이상운동증 환자의 한방 치험 1례

이상화,신희연,김정화,김연진,조승연,박정미,고창남,박성욱,Lee, Sang-hwa,Shin, Hee-yeon,Kim, Jeong-hwa,Kim, Yeon-jin,Cho, Seung-yeon,Park, Jung-mi,Ko, Chang-nam,Park, Seong-uk 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5

Objectives: The objective of this study was to report a clinical case that suggests potential beneficial effects of Korean medicine therapy for the treatment of levosulpiride-induced acute dyskinesia. Methods: A patient having drug-induced acute dyskinesia was given a series of Korean medicine therapy treatments, including administration of the herbal medicine Chengsimyeonja-tang-gamibang, acupuncture, electroacupuncture, pharmacopuncture, and moxibustion over the 17 days of the hospitalization period. During the therapy, the progression of the disease was measured by the Abnormal Involuntary Movement Scale (AIMS). Results: During the therapy, the remission of orofacial dyskinesia and improvement of AIMS scores were observed. Conclusion: Korean medicine therapy has potential benefits for the treatment of drug-induced acute dyskinesia.

기업의 리스크에 대한 보험대책 - 경제적 손해를 최소한도로 경감시켜야

이상화,Lee, Sang-Hwa 한국화재보험협회 1996 防災와 保險 Vol.68 No.-

비정형과 정형 주거공간의 시지각적 특성에 관한 연구

이상화,Lee, Sang-Hwa 한국주거학회 2007 한국주거학회 논문집 Vol.18 No.3

This study is aimed at understanding objectively on the visual perception of atypical space and form in contemporary architecture. It is accomplished to compose the various form and the atypical space in contemporary architecture, which by means of applying digital technology to architecture is able to materialize complicated form and space. Therefore this the sis is needed to understand user's senses and affects in atypical space and form. Atypical space is able to interpret geometrically and analyze quantitatively into visual perception. This analysis is applied to Isovist used as quantitative analysis recently, and physical analysis of space used as quantitative analysis defined to vertical elements, which is analysed comparatively to visual perception in observer's point and characteristics in spatial elements. Examples are selected to four examples represented to typical and atypical space in contemporary houses. As examples are analysed to visual perception of spatial character, this study is intended to understand to spatial character in aspects of spatial composition and observer's visual perception. In results of perceptive analysis on four spatial examples, Atypical spaces are composed of changeable spatiality, which are composed changeably of the relational method with adjacent spaces. Also, typical spaces are composed monotonously of spatiality and relational method on control of the length in boundary plane and openness.

화순 홍수조절지의 유입유출 구조물에 대한 수리모형실험 연구

이상화,진광호,류종현,김수근,Lee, Sang-Hwa,Jin, Kwang-Ho,Ryu, Jong-Hyun,Kim, Soo-Geun 한국수자원학회 2012 한국수자원학회논문집 Vol.45 No.7

Recently, a heavy rainfall under climate change causes the flood exceeded river's conveyance. Flood control methods under the limited river width are the increase of embankment, the construction of storage pockets and diversion channel, the dredging of river bed. Hwasun flood control reservoir of washland is designed as the storage pockets and the regulating gate for the control of water level. In this study, the propriety of design was investigated through hydraulic experiments for the circumstances to exclude the constant flood discharge during operation period. In the results, the over flow rate of side weir exceeded the flow of design and indicated to be able to discharge the designed flow in the regulating gate opened 1.1 m. The high velocity 7.1 m/s behind the gate has investigated to reduce under 3.3 m/s by the baffle block. 최근 기상변화에 의한 집중호우는 하천의 통수능력을 초과하는 홍수를 발생시키고 있다. 하천의 폭이 제한된 상태에서 이러한 초과 홍수에 대비할 수 있는 관리방법은 제방증고, 저류지 및 방수로 건설, 하상 준설 등을 생각할 수 있다. 천변저류지인 화순홍수조절지는 저류지와 수위조절을 위한 제수문이 설계되어 있다. 본 연구는 저류지 운영시간동안 일정 홍수량만을 배제해야 할 상황에 대해 설계의 적정성을 수리모형실험을 통해 검토하였다. 검토결과 저류지 유입부의 횡월류위어 월류량은 설계상의 월류량을 초과하였고, 제수문 1.1m 개방시 설계유량($326m^3/s$)을 방류할 수 있는 것으로 나타났다. 설계유량 방류시 제수문 직하류에 7.19m/s의 고유속은 baffle block을 설치할 경우 3.3m/s까지 저감시킬 수 있는 것으로 검토되었다.

출판저널 칼럼

이상화,Lee, Sang-Hwa 대한출판문화협회 1998 출판저널 Vol.242 No.-

위험관리와 보험

이상화,Lee, Sang-Hwa 한국화재보험협회 1978 防災와 保險 Vol.9 No.-