슬관절 전치환술 노인 환자를 위한 정맥혈전색전증 예방교육의 효과

이미희(Lee, Mi Hee),구미옥(Gu, Mee Ock) 기본간호학회 2019 기본간호학회지 Vol.26 No.4

Purpose: This study was conducted to develop and test the effects of venous thromboembolism prevention education for elderly patients with total knee arthroplasty. Methods: A non-equivalent control group posttest only non-synchronized design was used. The participants were 43 older adults (experimental group: 21, control group: 20) who had experienced total knee arthroplasty surgery at *university hospital located in *city. Venous thromboembolism prevention education consisted of a 20 minute intervention on the evening before the operation and a 5 minute intervention on the operation day including education and strategies for enhancing health belief. Data were collected from October 20, 2017 to March 10, 2018. Data were analyzed using independent t-test and Mann-Whitney U test with SPSS/WIN 24.0. Results: The experimental group showed significantly higher levels of knowledge, self-reported preventive behaviors, and number of ankle movements compared to the control group. Conclusion: The study findings indicate that venous thromboembolism prevention education can be recommended as an effective nursing intervention for preventing venous thromboembolism of elderly patients with total knee arthroplasty.

고성오광대 문둥북춤에 나타난 지역성에 관한 연구

김운미 ( Woon Mee Kim ),이미희 ( Mi Hee Lee ) 대한무용학회 2007 대한무용학회논문집 Vol.51 No.-

This study was focused on ascertaining a locality through Goseong Five-Clown Leper Drum Dance, one of the traditional dances in which Korean traits are distinctly expressed. Since dance is the surface culture of human life, looking for the character of a region expressed through dance is a way to discover the identity of our dance. Therefore, this study, as the first step of the plan, analyzes the relationship between the dances of Mundunbukchum of Goseongogwangdae and the regional characters, by studying the relevant literature and video documents. The results are the followings. First, its motion had been arranged with local characteristics over time. Such characteristics are distinctly shown in realistic expression and descriptive construction. Second, connection and diversion, the unique factors of the dances of the residents in Southern Gyeongsang Province, and impromptuness, periodical repetitivity and nonspeaking solo dances, the characteristics of the Leper Drum Dance express local characteristics well. Third, the locality is well shown in the significance of snare drums and the conflict between lepers, and also Goseong Five-Clown Leper Drum Dance is esthetically significant even in performing arts. Fourth, the form has reduced and established into a one-man dance while it flew into the local culture from the preceding region as a local cultural character. Fifth, the regional character of Gos대ng was derived through the realistic descriptive movement such as “Picking the ears of barley.” Sixth, the communications between entertainers and the audience took place in the Madang, a large circular space which the public entertainment culture is easily accessible to in the Goseong region that does not have hilly areas but much extensive field. On this wise, the general construction of the Leper Drum Dance and its motion were analyzed concurrently with local characteristics, and conversely, the locality was ascertained on the basis of the result. It is considered that such researches are significant in various aspects. Consequently, local dances should be continuouslyprotected and studied in respect that local characteristics have been expressed through dances and locality has been changed proportionally with the change of dancing characteristics.

보체 인자 9 결핍을 동반한 수막구균성 수막염 1례

최선미,이경일,이형신,홍자현,이미희,이병철,Choi, Sun-Mee,Lee, Kyung-Yil,Lee, Hyung-Shin,Hong, Ja-Hyun,Lee, Mi-Hee,Lee, Byung-Cheol 대한소아청소년과학회 2005 Clinical and Experimental Pediatrics (CEP) Vol.48 No.1

저자들은 12세 여아로 수막구균 수막염에 이환 후 시행한 보체 검사에서 C9 결핍을 확인한 1례를 경험하였다. 수막구균 수막염에 이환된 환아에 대한 보체 검사는 보체 결핍을 갖는 환자와 가족 내 위험이 있는 사람을 찾아내어, 향후 예방접종 등의 예방과 감염 관리에 필요하다. Meningococcal disease is not rarely associated with abnormalities of the complement system. We experienced a case of C9 deficiency with meningococcal meningitis from a 12-year-old girl. Identification of complement deficiency has implications for management, including family studies, prophylaxis, vaccination, and altered threshold for infection screening and treatment.

유기주석화합물이 명주조개 ( Coelomactra antiquata ) 의 약물대사효소계에 미치는 영향

전중균(Joong Kyun Jeon),이미희(Mee Hee Lee),김도진(Do Jin Kim),심원준(Won Joon Shim),오재룡(Jae Ryong Oh),이수형(Soo Hyung Lee) 한국수산과학회 2002 한국수산과학회지 Vol.35 No.2

강원 북부연안에 많이 서식하는 명주조개 (C. antiquata)를 대상으로 중장선의 미크로좀을 in vitro로 유기주석화합물 (TBTO, TBTC, TPTC)과 배양하여 약물대사효소계의 cytochrome P450 (CYP)과 7-ethoxyresorufin-O-deethylase (EROD)의 변화를 조사하였다. 그 결과, 이들 화합물은 모두 명주조개의 약물대사효소계를 짧은 시간 내에 저해한다는 것을 확인하였다. 즉, 미크로좀을 0.4 mM농도의 TBTC, TBTO 및 TPTC와 20분간 배양한 후의 CYP 함량은 첨가하기 전에 비해 각각 52%, 72% 및 40%로 줄었는데, 이것으로 화합물의 종류에 따라서 저해 정도는 차이가 있었고 butyltin화합물보다는 phenyltin화합물의 저해 정도가 더 컸다. 그리고 EROD 활성의 경우도 0.4mM의 TBTC, TBTO 및 TPTC와 20분간 배양하였더니 각각 100%, 92% 및 85%로 butyltin 화합물보다는 phenyltin 화합물의 저해가 더 컸다. 한편, TBTC, TBTO 및 TPTC 모두는 패류 중장선의 CYP와 EROD 활성을 농도의존적으로 저해하였으며, 그리고 두 효소는 모두 오염물질에 노출된 패류의 좋은 생체지표 (bioindicator)로 활용할 수 있을 것이라 여겨진다. This study was carried out to measure the in vitro interaction of trialkyltin with the microsomal monooxygenase (MFO) system of the clam, Coelomactra antiquata. Cytochrome P450 (CYP) level and 7-ethoxyresorufin-O-deethylase (EROD) activity were inveti-gated in the microsome isolated from digestive gland of the clam (C. antiquata) exposed to tributyltin chloride (TBTC), bis-tributyltin oxide (TBTO) and triphenyltin chloride (TPTC). The specific contents of CYP in clam microsome exposed to 0.4 mM TBTC, TBTO and TPTC for 20 minutes were decreased 52, 72 and 40%, respectively, compared to control group. The EROD activities also were inhibited by exposure to TBTO (92%) and TPTC (85%) except for TBTC. The level of CYP and the EROD activities were decreased according to the OTC exposure concentrations. The toxic effects on the level of CYP and the EROD activities were in order of TPTC >TBTC >TBTO in this study. The measurement of CYP level and EROD activity could be applied as a biomarker for environmental study.

Cytochrome P450 유도제에 노출시킨 명주조개 ( Coelomactra antiquata ) 약물대사효소계의 in vitro 반응

전중균(Joong Kyun Jeon),이미희(Mee Hee Lee),심원준(Won Joon Shim),이수형(Soo Hyung Lee) 한국수산과학회 2002 한국수산과학회지 Vol.35 No.2

강원 북부 연안에 많은 명주조개 (Coelomactra antiquata)의 중장선으로 미크로좀을 만들고, cytochrome P450 (CYP)의 유도제로 알려진 phenobarbital (PB), 3-methylcholanthrene (MC) 및 β-naphthoflavone (BNF)을 DMSO에 녹여 함께 30℃의 수조 상에서 in vitro로 배양하면서 약물대사효소계의 CYP 함량과 7-ethoxyresorufin-O-deethylase (EROD) 활성의 변화를 경시적으로 조사하였다. 그리고 비교를 위한 sham구는 미크로좀에 DMSO만을 첨가하여 같은 조건으로 배양하였다. 그 결과, sham구의 CYP 함량은 배양 6시간이 지나서는 처음 수준의 91%로 줄었으며, 0.1 mM과 0.2mM, 0.4mM 및 1.0mM BNF 배양구는 배양 4∼6시간 후에 최대값이 되었는데 각각 처음보다 116%, 114%, 126% 및 132%로 되었다. PB와의 배양에서는 0.1 mM과 0.4mM 및 1.0nIM 배양구는 배양 4∼6시간 후에 최대값이 되었고 각각 처음의 112%, 114% 및 114%로 되었으며, MC와의 배양에서도 0.1 mM과 0.4mM 및 1.0mM 배양구는 배양 4시간 후에 최대값이 되어 각각 116%, 130% 및 132%로 증가하였다. 그리고 EROD 활성의 변화도 sham구는 배양 7시간 후에도 변화가 거의 없었으나, BNF의 0.1 mM과 0.4mM 및 0.8mM 배양구는 배양 7시간 후에 각각 처옴의 120%, 123% 및 115%로 되었고, PB의 0.1mM과 1.0mM 배양구는 배양 3시간 후에 최대로 되어 각각 121% 및 136%로 증가하였으며, MC와의 배양에서는 0.1mM과 0.4mM 및 0.8mM 배양구는 배양 5시간 후에 최대값이 되어 각각 204%, 198% 및 191%로 증가하였다. 이처럼 BNF나 PB, MC는 명주조개에서도 미크로좀의 CYP 함량과 EROD 활성을 증가시키는 유도효과를 나타내었으며, 특히 MC에 의한 유도효과가 가장 강했고 BNF, PB의 순이었고, 대체로 약물의 농도가 높을수록 유도 효과도 큰 경향을 보였다. Induction of cytochrome P450 (CYP) and 7-ethoxyresorufin-O-deethylase (EROD) in the microsome exposed to 3-methylcholan-threne (MC), β-naphthoflavone (BNF) and phenobarbital-Na (PB) was investigated. Microsome was isolated from digestive gland of clam (Coelomactra antiquata) and then exposed to each chemical in concentration range of 0.1 to 1.0 mM for 7 hours. The CYP content and EROD activity in the microsome exposed to each chemical significantly increased compared to the control group. The overall CYP and EROD induction potency was in order of MC>BNF>PB. The induction response of EROD was two times higher than that of CYP level in the microsome exposed to MC, but the induction response of EROD was slightly higher than that of CYP level in BNF and PB exposure groups.

화소의 위치정보를 이용한 효과적인 Reversible 워터마킹

윤정혜(Jeong-Hye Yun),이미희(Mee-Hee Lee),정성환(Sung-Hwan Jung) 한국정보과학회 영남지부 2005 한국정보과학회 영남지부 학술발표논문집 Vol.13 No.1

인터넷의 급속한 발달로 인하여 디지털 데이터는 빠른 정보의 배포뿐만 아니라 복사본으로 쉽게 복제 및 변조가 가능하다. 이것을 방지하기 위하여 저작권 보호기법의 기술이 부각되고 있으나 이미 지의 왜곡을 피할 수 없어 화질의 저하를 가져온다. 본 논문에서는 이러한 화질 저하를 극복하여 화질에 민감한 군사 및 의료 영상에서도 사용할 수 있는 reversible 워터마킹을 연구하였다. 본 연구는 원 영상에 Hadamard matrix를 적용하여 워터마크 삽입이 용이한 이미지로 변환한 후, Seed 이미지와 델타 이미지를 생성하여 워터 마크를 삽입하고 추출하는 알고리즘을 제안한다. 이때 사용하는 워터마크 영상은 64X64 크기의 시각적으로 쉽게 인지 할 수 있는 연구실 로고인 이진 영상을 워터마크로 사용하였다. Lena를 포함한 여러 개의 표준 실험 영상들을 사용하여 실험한 결과, 워터마크가 삽입된 영상과 원 영상을 비교할 때 객관적인 PSNR 측정에서 약 4㏈을 유지하였으며, 주관적인 관찰에서도 시각적인 차이를 거의 느끼지 못하였다.

XML 문서에 대한 효율적인 검색기법

윤정혜 ( Jeong-hye Yun ),이미희 ( Mee-hee Lee ),우용태 ( Yong-tae Woo ) 한국정보처리학회 2004 한국정보처리학회 학술대회논문집 Vol.11 No.1

최근에 전자상거래, e-learning, e-book 등과 같은 다양한 분야에서 디지털 문서의 효율적인 관리를 위하여 XML문서를 이용하고 있다. 이에 따라 대량의 XML 문서들을 효율적으로 저장하고 관리하는 시스템의 필요성이 증가하고 있다. 이러한 시스템의 대부분은 XML 문서가 트리 구조로 이루어져 있기 때문에 DOM을 이용하고 있다. 그러나 DOM은 문서 전체의 문서 구조 정보를 메모리 트리 구조로 생성하는 과정에서 많은 시스템 자원을 필요로 한다. 본 논문에서는 이벤트-기반인 SAX를 이용하여 문서의 구조 정보를 내부 트리 구조로 만드는 대신 구문 분석 이벤트를 직접 응용프로그램에 전달하는 방법을 사용함으로써 DOM에서의 시스템 자원을 많이 사용하는 문제를 해결하였다.

소엽 Ethyl acetate 분획의 세포독성 평가

김성은,천현자,김일광,한두석,이현옥,안종웅,이미희,백승화,Kim Sung-Eun,Chun Hyun-Ja,Kim Il-Kwang,Han Du-Seok,Lee Hyun-Ok,Ahn Jong-Woong,Lee Mee-Hee,Baek Seung-Hwa 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.2

The Cytotoxic activity of the ethyl acetate soluble fraction of Perilla frutescens on human oral epithelioid carcinoma cell lines was evaluated by 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyl-2H-tetrazalium bromide (MTT) colorimetric method. The light microscopic study was carried out to observe the morphological changes of cultured human oral epitheloid carcinoma cell lines (KB) These results were obtained as follows; 1. subfraction 1 of the ethyl acetate soluble fraction of perilla frutescens was shown significant cytotoxic activity (p<0.001) at 10-2 mg/ml concentration, this concentration was decreased the cytotoxic activity of 70.3% . 2. The comparison of IC50 values of various subfractions in human oral epithelioid carcinoma cell lines was exhibited that their susceptibility to these subfractions decreased in the following order ; subfraction 5 > subfraction 4 > subfraction 3 > subfraction 2 > subfraction 1 by MTT assay. In light microscopy, the subfraction 1 of the ethyl acetate soluble fraction of Perilla frutescens showed the highest cytotoxic activity. These findings suggest that subfraction 1 possessed the most cytotoxic constituents.

카드뮴 독성으로 손상된 NIH 3T3 섬유모세포에 대한 어성초 추출물의 재생효과(VII)

이정호,오현주,정승일,천현자,한두석,이현옥,안종웅,이미희,백승화,Lee Jeong-Ho,Oh Hyun-Ju,Jeong Seung-Il,Chun Hyun-Ja,Han Do-Seok,Lee Hyun-Ok,Ahn Jong-Woong,Lee Mee-Hee,Baek Seung-Hwa 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.2

This study was carried out to evaluate antitoxic effects of Houttuynia cordata extract on cadmium by colorimetric methods. The antitoxic activity ofc in NIH 3T3 fibroblasts was evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide) and SRB (sulforhodamine B protein) assays. The light microscopic study was carried out to observe morphological changes of the treated cells. The concentration of 10-2 mg/ml of Houttuynia cordata extract was shown significant antitoxic activity. The number of NIH 3T3 fibroblasts were antitoxic and tend to regenerate. These results suggest that the ethyl acetate extract of Houttuynia cordata retains a potential antitoxic activity.

각 국가별 치과의료보장의 유형과 치과의료보험급여화에 관한 연구

이미희 제주관광대학 2001 論文集 Vol.7 No.-

치과의 진료는 발치, 충전, 치료에 한하므로 치아결손에 따른 보철을 실시하였을 경우에는 이에 소요된 비용은 본인이 전액 부담하고 있다. 우리나라는 상당수의 국민들이 아직도 과중한 진료비 부담 때문에 치아결손부를 방치하고 있거나 아니면 의료기관을 이용하지 않고 부정구강 진료업소에서 보철진료를 받고 있는 실정이다. 본 논문에서는 부정구강진료에 대한 예방책의 하나로써 외국의 의치보철실시에 관한 사례를 연구하므로서 의료보험의 요양급여화의 필요성을 제시한다. Research shows that, when dental-medical security was adopted, 45.4% of the old people who were over sixty-five needed a full denture: 28% of them needed a full denture in an upper jaw and 19.6% needed it in a lower jaw. According to the Data in 1995, 4% of old people who were aged from 65 to 74 needed afull denture in the upper jaw was 3% and in the lower jaw was 1%. The denture-need rate in 1995 is very different from the full denture need rate in 1978. The data in 1978 show that the partial denture installation rate of those who were over sixty-five in case of the upper jaw was 19.5% and of the lower jaw was 9.9%. The total partial denture installation rate in 1978 was 29.4%. That teels the difference between in 1978 and in 1995. The rate in 1995 is 24.5% higer than in 1978. It is reporated that in case of the upper jaw, the partial denture-need rate was 29.2% and in case of the lower jaw, 33.5%-the total was 62.7%- in 1978. If the installation rate and the need rate were mixed, the total partial denture need rate is 67.6%. The data in 1995 reported that the partial denture need rate of the upper jaw was 12.0% and that of the lower jaw was 18.2% and the total was 30.2%. So the installation rate and the need rate made 59.5% in 1995. In Japan, the old people aged over seventy have the benefits of the denture from medical system and in England the old people aged over sixty-five are exempted from individual of expenditure. Medicare in America provides the old over sixty five with good medical service and in Alberta, Canada, those who are over sixty-four are supplied with the expense of the denture by medical ibsurance system. The countries which inclued the denture installation into the expense list of the medical insurance system are carrying the inclusive grant. The Dutch children and adolescences under nineteen are furnished Br and Crown by the medical insurance system. In Danmark.