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Isoproterenol 정주에 의한 심박수의 변화가 고혈압 환자의 대동맥 경직도에 미치는 영향
이무용 ( Moo Yong Rhee ),권나영 ( Na Young Kwon ),김재덕 ( Jae Deok Kim ),송승호 ( Seung Ho Song ),윤영원 ( Young Won Yoon ),이명용 ( Myoung Yong Lee ),김영권 ( Young Kwon Kim ) 대한내과학회 2003 대한내과학회지 Vol.64 No.1
목적 : 고혈압 환자에서 대동맥 경직도의 증가는 심혈관 질환의 위험도를 반영하는 독립적인 위험인자로, 혈압의 상승이나 교감신경계의 항진은 대동맥의 경직도를 증가시킨다. 그러나 인공심박기에 의한 심박수의 상승은 대동맥의 경직도를 증가시키지 않는 것이 보고되고 있다. 본 연구에서는 고혈압 환자에서 교감신경계 흥분제인 isoproterenol을 투여하여 심박수를 상승시켰을 때 대동맥 경직도의 변화를 연구하였다. 방법 : 고혈압 환자를 대상으로 하였으며, 연구 Background : Increased aortic stiffness (AS) is an independent risk factor of cardiovascular disease in patients with hypertension. Elevation of blood pressure (BP) or sympathetic tone increases AS. It was reported that acute changes in heart rate by arti
경기 일부 지역 중년 성인의 식사 패턴에 따른 대사증후군 위험에 관한 연구
이유신(You Sin Lee),이무용(Moo Yong Lee),이심열(Sim Yeol Lee) 대한지역사회영양학회 2014 대한지역사회영양학회지 Vol.19 No.6
The aim of this study was to assess how nutrient intakes are related to risk factors for metabolic syndrome according to dietary patterns in the middle-aged adults. Methods: The subjects (n = 187; 47 men, 140 women) consisted of middle-aged adults over 30 years old in Ilsan area. The metabolic syndrome was diagnosed according to the data collected from each subject, including anthropometric measurements and blood analyses. The dietary patterns were derived from the average of two-day dietary intake data. Results: Factor analysis identified three major dietary patterns which were “Meats and alcohol”, “Mixed grains, vegetables and fruits”, and “Rice, Kimchi and fish & shellfish”. The daily intakes of energy, protein, and sodium increased across quartiles of “Meats and alcohol” pattern scores (p < 0.05), whereas the intakes of carbohydrates, potassium, calcium, and fiber increased across quartiles of “Mixed grains, vegetables and fruits” pattern scores (p < 0.001). The “Meats and alcohol” pattern scores were positively correlated with protein and sodium intakes but inversely correlated with carbohydrates, fiber and potassium intakes which were adjusted for age, sex and energy (p < 0.05). The highest quartile pattern score of “Meats and alcohol” pattern had elevated odds ratio of abdominal obesity and metabolic syndrome (p < 0.05). The risk of hypertriglyceridemia decreased in the highest quartile of “Mixed grains, vegetables and fruits” pattern (OR 0.35, 95% CI 0.12-1.00). Conclusions: Our results suggested that reducing the consumption of meat and alcohol along with increasing fruits, vegetables and mixed grains would be helpful for preventing the metabolic syndrome and chronic diseases.
이병은(Byeong-Eun Lee),김종인(Jong-In Kim),김무용(Moo-Yong Kim) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.11
Moisture contained in the steam generated in the steam generator for large nuclear power plants is removed initially in the moisture separator by the centrifugal force acting on them. Then, the rest of moisture, which is composed of relatively small water droplets, is removed in the dryer vane by inertia force and finally dry steam, which is almost superheated steam, is produced in the steam generator and it is sent to steam turbine to produce electricity. The mechanism of moisture removal is quite complex because of complex geometry and complex flow behavior in it. CFD techniques have been used to investigate the flow behavior and calculate the moisture removal efficiency in the present study. Unit cell test has also been conducted to validate CFD results. Comparison of the numerical predictions for the water droplet removal in a steam generator with experimental data shows very good agreement. However, only CFD results have been discussed in this paper.
최락경(Rak Kyeong Choi),이무용(Moo Yong Rhee),전원호(Won Ho Jeon),김인수(In Su Kim),김석연(Seog Yeon Kim),전용덕(Yong Deog Jeon),이홍순(Hong Soon Lee),유수웅(Soo Woong Yoo),이학중(Hak Choong Lee) 대한내과학회 1995 대한내과학회지 Vol.49 No.5
N/A Objectives: The exercise test is commonly used in conjunction with baseline clinical information to estimate the likelihood that a patient has significant coronary diseases. The purpose of this study was to determine if patterns of ST depression or elevation during exercise testing provide reliable information about the location of an underlying coronary lesion. Methods: We reviewed 49patients out of 137patients who performed treadmill test and coronary angiography at National Medical Center from January, 1984 through August, 1993. All the patients underwent modified Bruce protocol treadmill exercise test and coronary angiography. Exercise ST changes were classified as depression or elevation by lead groups involved(V1-V3, V4-6, I AVL, II III AVF), Coronary angiography was done in several oblique projections and results were reviewed by at least two senior angiographers. Results: 1) There were significant stenosis in coronary angiography in 22cases(70.9%) among positive 31cases, 0cases(0%) among borderline positive 4cases, 5cases(10.2%) among negative 49cases. 11cases(47.8%) among nondiagnostic 23cases, and 3cases(25%) among pseudonormalization 12cases in exercise treadmill tests. 2) The sensitivity of treadmill exercise electrocardiography was 61.2%, and specificity was 81.8%. The sensitivity of each coronary artery diseases was 6l.7% in Left anterior descending artery disease, 66.6% in Right coronary artery disease, 38.5% in Left circumflex artery disease, 100% in 2-vessel disease, and 100% in 3-vessel disease. 3) ST depression was not useful in predicting the site of coronary artery narrowing. In contrast, ST elevation was correlated with coronary artery disease. 4) ST depression was most often seen in leads V4-V6 and leads II III AVF without correlation between the diseased coronary artery and the leads in which ST depression occurred. Conclusion: The exercise treadmill induced depression of the ST segment is an significant sign for predicting the presence of coronary artery disease and for the decision to perform coronary angiography. But, site of ST depression during exercise is not a good predictor of anatomic site of coronary artery disease. The other noninvasive test and coronary angiography may be necessary to nondiagnostic group which revealed insufficient exercise load or target heart rate during exercise test because the presence of coronary artery disease can't be ruled out.
이창원(Chang Won Lee),장덕환(Duk Whan Jang),백인석(In Seok Baek),김장원(Jang Won Kim),배순철(Soon Chul Bae),김철우(Cheol Woo Kim),권재구(Jae Koo Kweon),최락경(Rak Kyeong Choi),이무용(Moo Yong Rhee),이홍순(Hong Soon Lee),유수웅(Soo Wo 대한내과학회 1997 대한내과학회지 Vol.52 No.4
N/A Objectives: Signal-averaged electrocardiography (SAECG) has been found to be a useful noninvasive technique for identifying patients at risk for life-threatening ventricular tachycardia. Delayed and fragmented activation of abnormal myocardial tissues causes the occurrence of high frequency low amplitude (HFLA) electocardiographic signals or late potentials. Generally, there are two methods in analyzing signal-averaged electrocardiography. Late potentials in the time domain analysis do not provide sufficient diagnostic power with regard to life-threatening Ventricular tachycardia. Buckingham et al. (1989) reported a time-domain sensitivity of 62%, a specificity of 75%. Spectral turbulence analysis (STA) of the signal-averaged ECG is the most recent frequency domain technique to improve the time domain sensitivity and specificity. So, We designed the study to compare the efficacy of Time Domain Analysis and Spectral Turbulence Analysis among five groups (Normal control, QRS widening, Postmyocardial infarction, Frequent VPC's with group beats, Nonsustained ventricular tachycardia). Methods: 88 patients were selected from the patients who had been admitted between January 1994 and October l994, at National Medical Center. Patients were divided into five groups, which were respectively, Group A: Normal control group (n=33), Group B: QRS widening group (n=14), Group C: Postmyocardial infarction group (n=10), Group D: Frequent VPC's with group beats (n=22), Group E: Nonsustained VT group (n=9). We compared Spectral Turbulence Analysis and Time Domain Analysis of Signal-Averaged Electrocardiogram by 24 hours-Holter monitoring. Results: 1) In normal control group(Group A), 9.1%(3 patients) were positive by Time Domain Analysis, but, all were negative by Spectral Turbulence An- alysis. 2) In QRS widening group (Group B), 71.4%(10 patients) were positive by Time Domain Analysis, but, all were negative by Spectral Turbulence Analysis. 3) In postmyocardial infarction group (Group C), 309o were positive by Time Domain Analysis, and 10% were positive by Spectral Turbulence Analysis. 4) In frequent VPC's group (Group D), 22.7% (5 patients) were positive by Time Domain Analysis, and, 4.5%(1 patient) was positive by Spectral Tur-bulence Analysis. 5) In Nonsustained VT group (Group E), 33.3% (3 patients) were positive by Time Domain Analysis, and 11.1% (1 patient) was positive by Spectral Turbulence Analysis. Conclusions: In Time Domain Analysis, abnormal results were presented at Group R (QRS widening group) by 71.4%, which was markedly higher than other groups. But, in Spectral Turbulence Analysis, abnormal results were not presented at Group A and Group B. In Group A and Group B, Spectral Turbulence Analysis shows less false positive results than Time Domain Analysis.
오형태(Hyung Tae Oh),이무용(Moo Yong Lee),송일한(Il Han Song),박석건(Seok Gun Park) 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.3
In patients with chronic liver disease,hepatopulmonary syndrome, the right to left shunt without previous pulmonary and cardiac disease, can develope and cause respiratory distress. Tools to prove shunt are contrast echocardiography, pulmonary angiography, and ^99mTC-MAA perfusion lung scan. Among them, ^99mTc-MAA scan is a simple and safe method detecting the right to left shunt. At the same time, quantitation of shunt amount is possible by this method. We report a case of hepatopulmonary syndrome confirmed by ^99mTc-MAA scan and contrast echocardiography with review of literlatures. (Korean J Nucl Med 2002;36;203-8)