소비음(消肥飮)이 비만아의 체질량지수와 비만도 감소에 미치는 영향

이동형,김덕곤,Lee, Dong-Hyung,Kim, Deog-Gon 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.1

Objectives The purpose of this study is to evaluate the effects of Sobieum on decrease of BMI and obesity index of obese children. Methods 66 children (33 boys, 33 girls) were involved in this study. We measured height and weight for each time their visit, and calculated BMI and obesity index. Results After medication, BMI level and obesity index were significantly reduced (p<0.001). Conclusions We speculate that Sobieum is effective in the treatment of childhood obesity, and further controlled studies are needed with clinical cases of hematological evaluation.

골연령의 측정에서 Greulich-Pyle법, Tanner-Whitehouse법, 완관절 초음파 통과속도를 이용한 골연령 측정법의 비교 연구

이동형,이진용,김덕곤,Lee, Dong-Hyung,Lee, Jin-Yong,Kim, Deog-Gon 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.2

Objectives : The purpose of this study was to evaluate the correlation of 3 methods of bone age measurements. Methods : 102 children(49 boys, 53 girls) were involved in this study. We measured the height, weight and bone age based when they visited for the first time. We measured bone age using BoneAge of Sunlight Co.,Ltd. Two of the bone age measurement methods, Greulich-Pyle and Tanner-Whitehouse, were used to analyze the left dorsopalmar hand-wrist radiographs of 102 children who visited in Department of Pediatrics, O O University Oriental Hospital. This study was designed to investigate the correlation of the bone age between two methods. Results : The bone ages were related with age, height, weight and BMI according to this study(P<0.01). Each bone age assessment method had statistically significant correlation to each other(P<0.01). Conclusions : The ultrasound transonic velocity of inferior radiocarpal joint will become a sufficient diagnostic tool of bone age assessment if measurement error can be minimized by proper effort.

8-Hydroxyquinoline 誘導體에 關한 硏究 (第2報) Fe (II)-7-Nitroso-8-Hydroxyquinoline-5-Sulfonate 에 關하여

이동형,Lee, Dong-Hyung 대한화학회 1965 대한화학회지 Vol.9 No.1

The properties of Fe(II)-7-nitrose-8-hydroxyquinoline-5-sulfonate have been studied spectrophotometrically at 700$m{\mu}$, $26^{\circ}C$. The absorbance of the complex shows a maximum at pH 6.0 and good thermal stability. Excess of the ligand and the reducing agent do not interfere the formation of the complex. The composition of the complex is found to be 3:1 ligand to metal species by molar ratio and continues variation methods. Calibration curve follow Beer's law over the range of concentratiion studied. 7-Nitroso-8-hydroxyquinoline-5-sulfonate의 Fe(II)錯鹽의 性質을 700$m{\mu}$, $26^{\circ}C$에서 分光光度法으로 調査하였다. 이 錯鹽은 pH6.0에서 가장 큰 吸光度를 나타내며 熱安定度도 대단히 좋다. Ligand나 Fe(III)의 還元에 使用한 hydroxylamine이 過剩으로 存在할때 에도 錯鹽의 生成에 影響을 주지 않는다. 錯鹽의 組成을 몰比法과 連續變化法으로 調査한 結果, 金屬과 ligand의 몰比는 1:3이였다. 檢量線은 實驗한 濃度範圍內에서 Beer의 法則에 따른다.

용적변조회전 방사선치료에서 선량전달의 중단 및 재시작에 따른 정확성 평가

이동형,배선명,곽정원,강태영,백금문,Lee, Dong Hyung,Bae, Sun Myung,Kwak, Jung Won,Kang, Tae Young,Back, Geum Mun 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.1

목 적: 용적변조회전 방사선치료는 겐트리 회전과 다엽콜리메이터, 선량률이 연동되어 진행되며 치료 중 선량 전달의 중단이 발생한 경우 겐트리와 다엽콜리메이터가 최초위치부터 다시 동작하여 정지된 지점부터 선량전달이 재개된다. 본 연구는 용적 변조회전 방사선치료의 치료 중단과 재 진행에 따른 선량전달의 오차를 분석하고자 하였다. 대상 및 방법: 10명의 환자를 대상으로 전산화치료계획시스템(Eclipse V10.0, Varian, USA)을 이용하여 용적변조회전 방사선 치료 계획을 수립하였다. TRILOGY (Varian, USA)의 6 MV 선속을 이용하여 계획된 선량을 이차원 배열 검출기와 CUBE (IBA dosimetry, Germany)팬텀에 조사하였다. OmniPro I'mRT system (V1.7b, IBA dosimetry, Germany)을 통해 4회에 걸쳐 일반적인 선량전달의 일관성을 평가 하고 선량 전달의 중단 또는 도어 인터락 발생으로 인해 선량 전달이 중단되고 최초지점부터 다시 시작되어 조사되는 경우와 비교하여 감마지수(Gamma index)의 변화를 분석하였다. 결 과: 선량 전달이 정상적으로 이루어진 경우에 각각의 감마 평균 신호 값의 차이는 0.1로 나타났고, 선량 전달의 중단이 발생한 경우 0.128로 나타났으며 도어 인터락의 경우 0.141로 나타났다. 각각의 경우 감마 표준편차 값의 차이는 0.071, 0.091, 0.099로 나타났고, 감마 최대값의 차이는 0.286, 0.379, 0.413으로 나타났다. Gamma pass rate (3%, 3 mm)는 허용 오차 범위를 만족하였고, T검증 결과 95% 신뢰구간에서 P-value가 0.05 미만으로 유의한 차이를 보였다. 결 론: 본 실험에서 치료 중 선량 전달의 중단 및 재시작에 관한 정확성을 평가해 본 결과 통계적으로는 차이가 있으나 임상적으로 허용 오차 범위이내로 문제가 없다는 것을 알 수 있었다. 그러나 겐트리와 다엽콜리메이터, 선량률의 연동으로 정확성이 요구되는 치료방법인 만큼 선량적인 측면에서 치료 중단에 따른 차이는 간과할 수 없다. 그러므로 갑작스러운 치료 중단 상황이 발생한 경우 추가적인 정도관리 절차를 통해 정확한 선량평가가 이루어져야 할 것으로 사료된다. Purpose: The accurate movement of gantry rotation, collimator and correct application of dose rate are very important to approach the successful performance of Volumetric Modulated Arc Therapy (VMAT), because it is tightly interlocked with a complex treatment plan. The interruption and restart of dose delivery, however, are able to occur on treatment by various factors of a treatment machine and treatment plan. If unexpected problems of a treat machine or a patient interrupt the VMAT, the movement of treatment machine for delivering the remaining dose will be restarted at the start point. In this investigation, We would like to know the effect of interruptions and restart regarding dose delivery at VMAT. Materials and Methods: Treatment plans of 10 patients who had been treated at our center were used to measure and compare the dose distribution of each VMAT after converting to a form of digital image and communications in Medicine (DICOM) with treatment planning system (Eclipse V 10.0, Varian, USA). We selected the 6 MV photon energy of Trilogy (Varian, USA) and used OmniPro I'mRT system (V 1.7b, IBA dosimetry, Germany) to analyze the data that were acquired through this measurement with two types of interruptions four times for each case. The door interlock and the beam-off were used to stop and then to restart the dose delivery of VMAT. The gamma index in OmniPro I'mRT system and T-test in Microsoft Excel 2007 were used to evaluate the result of this investigation. Results: The deviations of average gamma index in cases with door interlock, beam-off and without interruption on VMAT are 0.141, 0.128 and 0.1. The standard deviations of acquired gamma values are 0.099, 0.091, 0.071 and The maximum gamma value in each case is 0.413, 0.379, 0.286, respectively. This analysis has a 95-percent confidence level and the P-value of T-test is under 0.05. Gamma pass rate (3%, 3 mm) is acceptable in all of measurements. Conclusion: As a result, We could make sure that the interruption of this investgation are not enough to seriously affect dose delivery of VMAT by analyzing the measured data. But this investigation did not reflect all cases about interruptions and errors regarding the movement of a gantry rotation, collimator and patient So, We should continuously maintain a treatment machine and program to deliver the accurate dose when we perform the VMAT for the many kinds of cancer patients.

한방소아과에 성장치료를 주소로 내원한 환아들의 양도락 특성에 관한 연구

이동형,이진용,Lee, Dong-Hyung,Lee, Jin-Yong 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.3

Objectives The object of this study is to investigate the characteristics of Ryodoraku score in the Children who visited Department of Pediatrics, Hospital of Oriental Medicinewith Growth treatment as a chief complaint. Methods Subjects were 58 children who visited Department of Pediatrics, Hospital of Oriental Medicine the first time with Growth treatment as a chief complaint. We measured the height and Ryodoraku score, and we also checked bone age from some of them. This study was designed to investigate the characteristics of Ryodoraku score in children with Growth treatment as a chief complaint. Results and Conclusions The results were follows 1. The average value of Ryodoraku score in 58 children was $41.8800{\pm}13.82641$. 2. The value of H1(肺), H5(三焦), H6(大腸), H2(心包), H3(心), F4(膀胱) and F5(膽) had significant statistical differences compared to its total average. 3. The value of F3(腎) had no relationship with Mid-Parental Height(MPH) percentile. 4. The value of F1(脾), F3(腎) and total average was classified by the height percentile values when children visitedand the difference between the predicted height percentile, and it resulted as there were no relationship between those two

7-Nitroso-8-Hydroxyquinoline-5-Sulfonate 에 依한 Co (Ⅱ) 의 吸光光度定量

이동형,Lee, Dong-Hyung 대한화학회 1965 대한화학회지 Vol.9 No.2

7-Nitroso-8-hydroxyquinoline-5-sulfonate(NHQS)는 pH 4.5에서 Co(Ⅱ)와 安定한 赤色 complex를 形成하므로 이것을 利用하여 NHQS에 依한 Co(Ⅱ)의 吸光光度定量方法을 檢討하였다. 吸光度는 528$m{\mu}$, $25^{\circ}C$에서 測定하였다. Co(Ⅱ)의 濃度 0.3∼6p.p.m에서 Beer의 法則은 成立하며 complex의 分子吸光係數는 $1.1{\times}10^4$이었다. 共存이온中 Fe(Ⅱ), Fe(Ⅲ), Cu(Ⅱ), Mn(Ⅱ), Hg(Ⅰ), CN-, EDTA 等은 本定量에서 妨害가 된다. Complex의 組成을 몰比法과 連續變化法으로 檢討한 結果 NHQS와 Co(Ⅱ)의 몰比는 3:1이었다. Spectrophotometric method for the determination of Co(Ⅱ) is developed based on the fact that Co(Ⅱ) forms a stable red complex with 7-nitroso-8-hydroxyquinoline-5-sulfonate at pH 4. 5. The absorbance is measured at 528$m{\mu}$, $25^{\circ}C$. Beer's law is followed in the concentration range of 0. 3 to 6. 0 p.p.m. of Co(Ⅱ) and molar extinction coefficient of the complex was $1.1{\times}10^4$. Of the diverse ions checked, Fe(Ⅱ), Fe(Ⅲ), Cu(Ⅱ), Mn(Ⅱ), Hg(Ⅰ), CN-, EDTA interfere. The composition of the complex is found to be 3:1 ligand to metal species by mole ratio and continuous variation methods.

8-Hydroxyquinoline 誘導體에 關한 硏究 5-Acetyl-8-Hydroxyquinoline의 酸解離定數

이동형,Lee, Dong-Hyung 대한화학회 1965 대한화학회지 Vol.9 No.1

5-Acetyl-8-hydroxyquinoline 의 酸解離定數를 $25^{\circ}C({\mu}$=0.1)에서 分光光度法과 pH滴定法에 依하여 測定하였다. 두 方法에 의하여 얻은 $pK_1$은 近似하게 一致하였으며 pK값은 8-hydroxyquinoline의 該當 pK값보다 작다. 그것은 acetyl group의 芳香族環에 대한 電子吸引性에 基因한 結果라고 생각한다. Acid dissociation constants of 5-acetyl-8-hydroxyquinoline have been determined by spectrophotometric and potentiometric methods at $25^{\circ}C$. $pK_1$, $pK_2$ values obtained by potentiometric method were 4.56, 8.20 respectively and $pK_1$ obtained by spectrophotometric method was 4.21. pK values were lower than those of 8-hydroxyquinoline. The lower basicity of 5-acetyl-8-hydroxyquinoline compared with 8-hydroxyquinoline was considered as the result of the electronic attraction of the acetyl group with aromatic ring.

8-Hydroxyquinoline 誘導體에 關한 硏究 (第 1 報) 7-Nitroso-8-Hydroxyquinoline-5-Sulfonate 의 合成과 그 酸解離定數

이동형,Lee, Dong-Hyung 대한화학회 1965 대한화학회지 Vol.9 No.1

8-Hydroxyquinoline-5-sulfonic acid 를 alkali 媒質에서 $10^{\circ}C$以下로 維持하여 nitroso 化시켜 7-nitroso-8-hydroxy-quinoline-5-sulfonate (NHQS)를 合成하였으며 그 酸解離定數를 分光光度法과 pH滴定法에 依하여 測定하였다. 두 方法에 依하여 近似하게 같은 값은 얻어졌고 이것들은 8-hydorxyquinoline의 該當 pK값에 比해 작다. 8-hydroxyquinoline에 比해 NHQS의 낮은 鹽基性은 導入된 電子吸引性基들의 影響으로 생각되며 特히 nitroso 基는 ortho位의 phenol性 OH基의 酸性度의 增加에 많은 影響을 주는 것으로 생각된다. 7-Nitro-8-hydoxyquinoline-5-sulfonate (NHQS) have been synthesized from 8-hydroxyquinoline-5-sulfonic acid by nitrosation in alkaline medium at temperature below $10^{\circ}C$ and the acid dissociation constants of NHQS have been determined by spectrophotometric and potentiometric methods. Almost same values are obtained by both methods but the values are lower than the corresponding 8-hydroxyquinoline. The lower basicity of NHQS is considered as the effect of electron withdrawing groups, especially adjacent nitroso group.

녹색 인광 유기발광다이오드에서 전하 조절층의 두께 변화가 성능에 미치는 효과에 대한 연구

이동형 ( Dong Hyung Lee ),이석재 ( Seok Jae Lee ),구자룡 ( Ja Ryong Koo ),이호원 ( Ho Won Lee ),이송은 ( Song Eun Lee ),양형진 ( Hyung Jin Yang ),박재훈 ( Jae Hoon Park ),김영관 ( Young Kwan Kim ) 한국유화학회 2013 한국응용과학기술학회지 Vol.30 No.2

본 연구에서는 전하 조절층을 이용하여 녹색 인광 유기발광다이오드의 효율의 향상을 나타냈다. 양극성의 4,4,N,N``-dicarbazolebiphenyl (CBP)를 호스트와 전하 조절층으로 사용하여 발광층 내에서 전하의 이동을 원활하게 할 수 있다. 게다가 전하 조절층의 삽입으로 엑시톤을 효과적으로 발광층 내에 제한하여, 삼중항-삼중항 소멸 현상을 억제할 수 있음을 확인하였다. 발광층의 전체 두께는 유지하고, 전하 조절층의 변화를 준 다섯 개의 소자를 제작하여 최적화된 전하 조절층의 두께를 이용한 Device D는 외부 양자 효율 16.22%와 휘도 효율 55.76 cd/A의 성능을 보였다. We investigated green phosphorescent organic light-emitting diodes (PHOLEDs) with charge control layer (CCL) to produce high efficiency. The CCL and host material which was 4,4,N,N`-dicarbazolebiphenyl (CBP) of bipolar property can control the carrier movement in emitting layer (EML). The performance improvement by the insertion of CCL was realized to the well confined exciton and the reduced triplet exciton quenching effect in EML. Five types of devices (Device A, B, C, D, and E) were fabricated following the thickness of CCL within EML. The properties of device D using optimized thickness of CCL showed external quantum efficiency of 16.22% and luminous efficiency of 55.76 cd/A, respectively.

H기업 프레스 작업자의 근골격계 질환 실태에 관한 연구

이동형 ( Dong Hyung Lee ),조기훈 ( Gie Hoon Cho ) 한국감성과학회 2003 춘계학술대회 Vol.2003 No.-

Recently, WRMSD(Work-Related Musculoskeletal Disorders) that can be frequently found among simple and repetitious works has been a big occupational safety issue, and has begun to being studied actively by many Korean researchers. However, those researches have been largely relied on foreign ones, due to the lack of basic data in Korea. In this study, we have tried to search the actual conditions and factors on WRMSD of press workers in a local company. In addition, we examined how the contents of works and postures of the workers affect the disease. It is expected that the data collected in this study will be able to used for planning the preventive measures on WRMSD effectively and for implementing its corresponding programs.