사료내 카드뮴 첨가가 체조직과 피모의 카드뮴, 아연, 철 및 구리함량에 미치는 영향

이근우,이현범,Lee, Keun-woo,Lee, Hyun-beom 대한수의학회 1987 大韓獸醫學會誌 Vol.27 No.2

This thesis was designed to find out whether the cadmium content of hair in living animals reflects the status of cadmium accumulation in internal organs or muscles so that this status can be used as a diagnostic method. Forty-five rats were divided into 4 experimental groups and one control group. The control group received a basal diet which contained zinc $100{\mu}g/g$, iron $80{\mu}g/g$ and copper $135{\mu}g/g$. The experimental group received experimental diets sllpplemented with 1, 10, 100 or $1,000{\mu}g/g$ cadmium as cadmium sulfate. Rats were dissected on the 28th or 56th day of experimental periods and tissues, blood and hair samples were taken, dried and burned to ash and analysed. The cadmium, iron zinc and copper concentrations were measured with an atomic absorption spectrophotometer. In addition feed efficiency and hematological changes were observed. The results obtained can be summerized as follows: A marked decrease in feed intake, weight gain and feed efficiency were observed from 1 or 2 weeks of experimental periods, which was in accordance with the dosage and periods. The cadmium contents of kidney, liver, spleen and muscle were significantly increased in all experimental rats; the accumulation was marked in kidney and liver tissues. It was shown that the cadmium contents of hair reflects the cadmium accumulation in internal organs and muscle; the higher the cadmium levels of diet and of rat tissues, the higher the cadmium content of hair. In the $100{\mu}g/g$ group of rats erythrocyte counts and. hemoglobin concentrations were decreased. A significant(p<0.01, p<0.05) increase in iron contents of kidney, liver and muscle was observed in 10, 100, $1,000{\mu}g/g$ groups of rats on the 28th day of experiment. A significant (p<0.01, p<0.05) increase in zinc contents of kidney, liver and muscle was observed in all experimental rats. On the other hand, serum zinc concentration was decreased. A significant(p<0.01) increase in copper contents in the liver was observed on the 28th day in $100{\mu}g/g$ and $1,000{\mu}g/g$ groups of rats. From these results it may be concluded that the analysis of hair for cadmium is a useful diagnostic approach for the cadmium status of internal organs and muscle in living animals.

섬유주세포에서 Dipyridamole이 활성산소종과 산화스트레스에 미치는 영향

이근우,김재우,Keun Woo Lee,Jae Woo Kim 대한안과학회 2013 대한안과학회지 Vol.54 No.3

Purpose: To investigate the effects of dipyridamole (DPD) on the production of reactive oxygen species (ROS) and oxidative stress in cultured human trabecular meshwork cells (HTMC). Methods: Antioxidant activity of DPD was determined by DPPH assay. Primarily cultured HTMC were exposed to 0, 20, and 50 μm DPD using serum-deprived media. The effect of DPD on the production of ROS was assessed with the DCHFDA assay. The effect of DPD on the t-butyl hydroperoxide (tBHP)-induced oxidative stress was assessed with resazurin assay. Results: DPD showed significant antioxidant activity. DPD significantly decreased the production of ROS (p < 0.05) and improved cellular activity significantly after treatment with t-BHP (p < 0.05). DPD did not affect the generation of nitric oxides. Conclusions: DPD suppressed the formation of ROS and possessed cytoprotective activity against the oxidative stress in HTMC.

Rat에 있어서 ethanol투여가 체조직의 무기질 함량에 미치는 영향

이근우,이현범,Lee, Keun-woo,Lee, Hyun-beom 대한수의학회 1989 大韓獸醫學會誌 Vol.29 No.1

This study was designed in order to clarify the effect of ethanol drinking on the mineral contents on liver, kidney, muscle and hair. Forty-five rats were divided into 2 groups and a control group. The control group received tap water and the other 2 groups were given 8% and 40% ethanol as drinking source. Liver, kindney, muscle and hair samples were taken and analyzed for zinc, calcium and copper contents by atomic absorption spectrophotometric methods. The results obtained are summrized as follows; 1. The zinc content of muscle showed significant (p<0.01) decrease in both groups. 2. The calcium content of hair showed significant (p<0.1) increase in 8% ethanol group. 3. The copper contents of kidney and muscle in 8% ethanol group and liver in 40% ethanol group showed significant (p<0.1) decrease.

수지접합 수복물용 합금의 피착면처리에 따른 결합력에 관한 실험적 연구

이근우,Lee, Keun-Woo 대한치과보철학회 1991 대한치과보철학회지 Vol.29 No.1

This study investigated the effects of surface treatment on the tensile bond strength of resinbonded prosthesis. The Rexillium III specimens were treated with $50{\mu}m\;Al_2O_3$ blasting. Type IV gold alloy specimens were treated with $400^{\circ}C$ heating and tin plating method. All specimens were bonded with MBAS composite resin cement and followed by immersion test into the $37^{\circ}C$ water bath for 7 days. The specimens were debonded in tension with an Instron machine and observed with SEM. The modes of failure were recorded also. The following conclusions were obtained : 1. The tensile bond strength decreased in following order. $50{\mu}m\;Al_2O_3$ basted Resillium III group, Type IV gold alloy group treated with $400^{\circ}C$ heat and tin plating type IV gold alloy group, and statistical significant differences were observed(p<0.05). 2. The tensile bond strength decreased in all groups after 7 days immersion test, but statistical significant differences were observed in Rexillium III specimens only. 3. The sharp and irregular surface were observed in Rexillium III, but $400^{\circ}C$ heat treated and tin plated groups had round and broad surface in SEM. 4. The models of bond failure were cohesive-adhesive failure mainly.

도저용 착시 도재-금속 개면에서의 원소이동에 관한 실험적 연구

이근우,이호용,Lee, Keun-Woo,Lee, Ho-Yong 대한치과보철학회 1987 대한치과보철학회지 Vol.25 No.1

This study was undertaken to observe the elemental transition of Interface depending on different pretreatment methods, the number of filings, the kinds of porcelain powders and the various alloys in ceramo-metal restoration. The materials used in this study were Pors-on $4^{(R)}$ and Ceramco porcelain powder to compare the differences depending on the pretreatement methods and the number of firings. Ceramco porcelain powder and Vita porcelain powder were used to compare the differences of elemental transition depending on the porcelain powders. The $Parasil^{(R)},\;PGV^{(R)}$ and Pors-on $4^{(R)}$ as Pd-Ag alloy were used to compare the difference of elemental transition depending on the various alloys. The pretreatment methods were : no treatment, treatment under vacuum and air, treatment with 50 % hydrofluoric acid and double heat tretament. The number of firings were 3, 5 and 7 repeated firings All specimens were observed by SEM and concentration of elements were analyzed quantitatively with EPMA The results of this study were obtained as follows : 1. In the groups of air-treatment, concentration of Sn were the highest and widest. A high concentration of In were in the groups of vacuum and air treatment. 2. There were no significant differences in concentration of Sn between the group of vacuum, 5 minutes hydrofluoric acid and double heat treatment. (p>0.05) 3. As the period of time of hydrofluoric acid treatment increased, not only were the trace elements reduced but the main components such as Pd and Ag were also reduced. 4. Concentration of Sn and In increased and diffused with repeated firings but 5 repeated and 7 repeated firings groups had no significant differences. (p>0.05) 5. Sn were more concentrated in the group of Ceramco porcelaion powder than Vita porcelain powder. 6. The higher concentration of trace elements in the alloy, the more increasing concentration of Sn and In in the interface.

사료내의 아연과 칼슘이 돼지 부전각화증의 발생에 미치는 영향

이근우,이현범,Lee Keun-Woo,Lee Hyun-Beom 대한수의사회 1984 대한수의사회지 Vol.20 No.1

Present experiments were conducted in order to clarify the effect of dietary low zinc and excess calcium on the zinc and calcium concentrations of serum and feces, and to show the therapeutic effect of external application of zinc or soybean oil on the sk

염화제이철 용액을 이용한 베릴륨동 기판의 식각 특성

이근우(Lee Keun Woo),이병욱(Lee Byung Wook),이태성(Lee Tae Sung),이종하(Lee Jong Ha),이재홍(Lee Jae Hong),김창교(Kim Chang Kyo) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.10

구리와 강철의 성질을 혼합한 것과 같은 우수한 성질을 갖고 있어서 열전도율이 좋고 내마모성이 뛰어난 베릴륨동 기판(BeCu foil)에 대한 식각 특성에 관하여 연구하였다. 일반적으로 베릴륨구리에 대한 식각용액은 염화제이철(FeCl₃)이 널리 알려져 있으며, 이 용액은 농도와 온도에 따라 식각시간이 달라지게 되어 식각되는 면의 상태가 영향을 받게 된다. 염화제이철의 농도를 변화시켜 본 결과 염화제이철의 농도가 증가할수록 식각률이 증가하였고, 염화제이철에 염산(HCl)을 첨가한 결과 식각률이 증가함을 알 수 있었다. 이는 염화제이철의 성분 중에서 염산(HCl)의 농도가 식각률에 영향을 미치고 있음을 나타낸다. 또한 영화재이철의 용도가 40℃ 일때 식각륜이 가장 우수하며 식각되는 면의 상태가 매우 양호해지고 식각되는 면의 각도도 수직에 가까워진다.

감치제도의 변용 혹은 오용: 질서벌로서의 신체의 자유 제한

이근우 ( Keun Woo Lee ) 법과사회이론학회 2011 법과 사회 Vol.0 No.41

Confinement has been in our legal system for quite some time. Although this system had not been in application for long since the birth of it, recently this system has been actively applied, since this system has been introduced in Court Organization Act as an exceptional system. Whole legal systems must comply with the constitutional spirit (such as Constituion of the Republic Korea, Article 37). In particular, the scheme involves the redemption of the body must balance the proportion. In this Act, the confinement system in terms of appearance has become the main sanction. Recent trends in the Criminal Procedure Code amendment would reduce the redemption of the body. However, detention system with the redemption of the body is developed especially in Civil Procedure law. The court summon witnesses to court is apprehension. I think that the intention of developing the confinement system is that the court wants easier way cause apprehension is not easy in reality. But I think detention system should be ``ultima ratio`` when other systems(e.g. departure of prohibition, witness who didn``t attend the court put on the computer network as a most wanted and so on) do not work properly and only in this case this system can be agreed. However it`s promoted widely its own territory in Act on the Regulation of Violations of Public Order. It`s criticized that this is because lawmakers and law-executors want a system that is too easy to apply.

큰구슬 우렁이 (Neverita didyma) 보일드 통조림의 加熱殺菌 條件에 따른 品質變化

이근우(Keun-Woo Lee),류홍수(Hong-Soo Ryu),주현규(Hyen-Kyu Joo) 한국식품영양과학회 1984 한국식품영양과학회지 Vol.13 No.3

西海産 큰구슬우렁이의 보다 效率的인 利用方案을 모색하기 위하여 試圖한 보일드통조림의 加熱殺菌條件究明 結果는 다음과 같다.<br/> 1. 큰구슬우렁이生肉은 高蛋白, 低脂肪食品이었으며, 特히 炭水化物含量은 1% 前後였다.<br/> 2. 加熱處理時 凝固性物質은 液汁 1ml當 0.37~0.40g N. 이상에서만 凝固現象이 일어났다. 따라서 105℃, 20分, 110℃, 40分, 115℃, 20分이상 처리 시에만 發見할 수 있었다.<br/> 3. 有效性 lysine은 110℃, 20分보다는 125℃, 20分에서 12% 減少하는 반면, 20分에서 109分까지는 約 17%~22.8%의 變化를 보였다.<br/> 4. 각 處理區의 生菌檢出은 110℃, 80分, 115℃, 40分 이상에서는 檢出되지 않았다.<br/> 5. 큰구슬우렁이 生肉에서는 tryptophan이 制限아미노산이었으며, 다른 貝類의 約 57%(0.83g/16g N.) 밖에 되지 않았고, 보일드肉에서는 methionine (보유율 87%)이 가장 많이 損傷되었다.<br/> 또한 PPDRI値는 生肉 63.16, 보일드肉 65.85(115℃, 40分 處理로 生肉보다 加熱處理肉이 높았다.<br/> 6. 이상의 結果로 보아 最適加熱殺菌溫度 및 時間은 生菌數, 凝固性物質, 有效性 lysine을 감안하여 115℃, 40分 處理가 바람직하다고 생각되었다. Changes in available lysine and water soluble proteins were checked to obtain the desirable condition of processing for boiled Neverita didyma under the various autoclaving temperatures and times. It was also carried out to assess the affect of heat treatments upon the solubility of coagulable substances in boiled products.<br/> In order to evaluate the nutritional quality of processed Neverita didyma under the highest available lysine retention and without bacteria, it was studied the value of pepsin-pancreatin digest residue index in comparison with unprocessed (raw) material.<br/> The crude protein content of raw material was higher than that of the other mollusks, while the content of crude fat was showing lower value. It was noticed that the higher contents of coagulable substances and water soluble proteins in processed Neverita didyma were obtained under the conditions, retort temperature at 120℃ above, and 40-60 min. sterilization.<br/> After the pannel test, the coagulable substances were not found below the level of 0.40±0.03 gram nitrogen/ml of juice. The remarkable retention of available lysine (FDNB-reactive lysine) was resulted in the conditions of autoclaving at 115℃ for 40 minutes in boiled Neverita didyma products, and that processing condition was coincide with the condition of commercial sterilization for boiled top shell. It was revealed that the boiled meat of Neverita didyma showed the higher PPDRI(65.85) than that of raw material (63.16).

신발 구성요인이 만족도 및 행동의도에 미치는 영향

이근우(Lee Keun Woo) 한국경영학회 2020 한국경영학회 통합학술발표논문집 Vol.2020 No.8