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족관절 외측 불안정성 재건 시 시행하는 탐험적 관절경의 유용성
이경태,김진수,양기원,박영욱,김준범,김태원,조재호,Lee, Kyung-Tai,Kim, Jin-Su,Young, Ki-Won,Park, Young-Uk,Kim, Jun-Beom,Kim, Tae-Won,Jo, Jae-Ho 대한족부족관절학회 2010 대한족부족관절학회지 Vol.14 No.2
Purpose: To evaluate the efficacy of the arthroscopic exploration combined with modified Brostrom operation (MBO) for the treatment of chronic lateral ankle instability (CAI). Materials and Methods: Sixty patients who diagnosed a CAI were performed MBO. We divided to 2 groups, whether simultaneously inspected by arthroscopy (group B) or not (group A). The both group's results were compared according to American Orthopedic Foot and Ankle Society Ankle-hindfoot score (AOFAS), functional ankle score and visual analog scale (VAS) at preoperative and final follow-up period. Results: There were no significant differences of AOFAS, functional ankle score and VAS between both groups at final follow-up. However, in group A, 2 cases associated with medial ankle instability and syndesmotic injuries were did not diagnosed preoperatively, showed poor prognosis. In group B, one case had a permanent peroneal nerve symptom. The match rate of intra-articular lesions between preoperative diagnosis and postoperative arthroscopic diagnosis was 30% in group B. Conclusion: Combination of arthroscopic exploration and MBO is effective strategy for intra-operatively discrimination of intra-articular associated lesions for CAI.
흰쥐의 배양 간세포를 이용한 세포독성시험에 있어서 뉴트랄레드 및 젖산 탈수소효소법의 비교
이경태,서성훈 ( Kyung Tae Lee,Seong Hoon Seo ) 한국약제학회 1995 Journal of Pharmaceutical Investigation Vol.25 No.4
The acute cytotoxicities of chloroquine sulfate, propranolol, ascorbic acid, acetylsalicylic acid and acrylamide on cultured adult rat hepatocytes were evaluated by the use of LDH leakage and NR uptake test. On the basis of IC_(50) values, the rank order of cytotoxicities of these drugs in both tests was chloroquine sulfate > propranolol > acetylsalicylic acid > ascorbic acid. The IC_(50) of LDH test was very similar to that of NR uptake test. Thus, we concluded that both tests are reliable and sensitive methods in detecting toxicity in adult cultured rat hepatocytes.
${\beta}$-시클로덱스트린과의 포접에의한 디플로페낙나트륨의 용해도 및 생체흡수율 증가
이경태,김종환,김주일,김승조,서희경,서성훈,Lee, Kyung-Tae,Kim, Jong-Hwan,Kim, Joo-Il,Kim, Seung-Jo,Seo, Hee-Kyoung,Seo, Seong-Hoon 한국약제학회 1996 Journal of Pharmaceutical Investigation Vol.26 No.3
Inclusion complexes of diclofenac sodium with ${\beta}-cyclodextrin$ were prepared in aqueous solution, alkaline solution and solid phase. The interaction of diclofenac sodium with ${\beta}-cyclodextrin$ in pH 9.0 alkaline solution was evaluated by the solubility method and the instrumental analysis such as thermal analysis, infrared spectroscopy, X-ray diffractometry. The solubility of diclofenac sodium was increased linearly with the increase in the concentration of ${\beta}-cyclodextrin$up to 0.15 mol and showed that the aqueous solubility rate of diclofenac sodium was significantly increased by complex with ${\beta}-cyclodextrin$. The optimum composition of this complex was one molecule of ${\beta}-cyclodextrin$ included 1.59 molecular weight of diclofenac sodium as a guest molecule. The pharmacokinetic parameters of the diclofenac sodium and the complex with ${\beta}-cyclodextrin$ were studied in rats by oral route. $T_{max}$ between drug alone and inclusion complex showed significant difference to be 120 minute and 20 minute respectively. Both of $C_{max}$ and AUC of inclusion complex was about 40% higher than drug alone. It is estimated from the data in this study that complexation of diclofenac sodium with ${\beta}-cyclodextrin$ increased the absorption rate and improved the bioavalability of the diclofenac sodium by the formation of a water-soluble complexes.
에칠렌디아민을 배위자로 한 백금(II) 착체의 합성과 항암효과
이경태,정지창,노영수,Lee, Kyung-Tae,Jung, Jee-Chang,Roh, Young-Soo 한국약제학회 1994 Journal of Pharmaceutical Investigation Vol.24 No.4
An attempt was made to develop new water-soluble antitumor Pt(ll) complexes containing ethylenediamine, and their structures were determined by infrared spectroscopy, $^{13}C$ nuclear magnetic resonance and elemental analysis. Their antitumor activities in vitro against L-1210, p-388 leukemia cells and M-14 melanoma cells were investigated and acceptable antitumor activity was found as compared with cisplatin.
한국 성인에서의 당뇨병성 족부 질환의 신발 및 족부 질환 연구
이경태,최병옥,Lee, Kyung-Tae,Choi, Byung-Ok 대한족부족관절학회 2003 대한족부족관절학회지 Vol.7 No.2
Purpose: To provide baseline data for prevention and education of diabetic foot in Korea. Materials and Methods: 216 diabetic patients are included in this survey. The average age is 58.64 year old with average 9.92 years of diabetes mellitus periods. Among them, 41% used insulin injection, 42% oral medication, 14% both and 3% diet were used for their blood sugar control. The diabetic foot survey was done. Results: The survey of patients symptom and disease of their feet results: 49% had sensory decrease in their feet. Associated disease in foot were callus(15%), heel pain(10%), bunion(4%), toe deformity(2%), Tinea pedis were 9%, tingle sensation were 17%, and swelling on feet were 2%, The survey of patients privious history of foot problems are: 8% had previous operation history on their feet and 17% had history of infection on their feet, 23% had bullae history, The survey of patients prevention and education are: Those who have had more than one diabetic foot education were 45.7%, and among them 24% had routine regular foot check up. Only 5% wear special diabetic shoe and 3% had custom orthotics. Conclusion: Interests to diabetic foot care is increasing in diabetic patients in Korea. However still we need more education, and efforts for prevention. Special education and diabetic shoe is still low, The survey data could be good baseline for diabetic prevention and education.
무지 외반증 환자의 근위부 절골술 후 발생한 의인성 제 1 중족골의 족배 굴곡증의 치료 -1예 보고-
이경태,양기원,김재영,차승도,김응수,손상우,Lee, Kyung-Tae,Young, Ki-Won,Kim, J-Young,Kim, Eung-Soo,Cha, Seung-Do,Son, Sang-Woo 대한족부족관절학회 2004 대한족부족관절학회지 Vol.8 No.2
Purpose: We report a case that iatrogenic dorsiflexion deformity after hallux valgus surgery treated successfully with crescenteric plantar flexion metatarsal osteotomy. Materials and Methods: 43 years old female who suffered from left fore foot pain and deformity after hallux valgus surgery was evaluated. Results: Preoperatively she did not put on ordinary shoes and had had persistent pain and discomfort on 1st metatarsal area. She also had a callus on plantar surface of 2nd metatarsal head. Simple AP and Lateral x-ray identified that 1st metatarsal bone had a 23 degree dorsiflexion deformity. For correction of deformity, plantarflexion crescenteric osteotomy was performed on proximal 1st metatarsal area. After operation, All of symptom eliciting patient was gone and 43 points of AOFAS scale preoperatively improve 100 points and the patient very satisfied. Post operative x-ray was showing complete correction of deformity. Conclusion: As a treatment of iatrogenic dorsiflexion deformity after hallux valgus surgery, the crescenteric plantar flexion osteotomy can be good and safe modality for correction.
이경태,양기원,김재영,차승도,김응수,손상우,Lee, Kyung-Tae,Young, Ki-Won,Kim, J-Young,Kim, Eung-Soo,Cha, Seung-Do,Son, Sang-Woo 대한족부족관절학회 2004 대한족부족관절학회지 Vol.8 No.2
Purpose: To analyze clinical symptom and clinical course of accessory navicular bone and to evaluation of surgery of accessory navicular bone in sports players Materials and Methods: Twenty-two patients with accessory navicular bone were identified between January 1 2001 and June 30. 2003 Results: Subjective satisfaction of 23 patients rated very satisfaction (16), satisfaction (6), common (1). Symptomatic pain were thoroughly disappeared at average 2.5 months ($1{\sim}6$ months) after operation. On one year follow-up, most of patients could maintain daily life and could go back to their sports carreer at 3 months. Conclusion: In athlete, excision of accessory navicular and reattachment of posteior tibial tendon to navicular like non-athletes is the best solution to management of symptomatic accessory navicular failed to manage conservatively.
이경태,송춘호,Lee Kyung-Tae,Song Choon-Ho 대한침구의학회 1998 대한침구의학회지 Vol.15 No.2
This study examined the histomorphomeric and histological changes of the left and right kidney in uninephrectomized rat. The results were as follows: 1. In the control, the right kidney was more prominent than the left in the basement membrane of glomerular capillaries. The podocyte had well developed Golgi apparatus in the left kidney and rough endoplasmic reticulum in the right kidney. 2. At the 30 days after unilateral nephrectomy, the basal lamina of glomerular capillaries was prominently thickened in the right kidney. The cytoplasm of the podocyte of the left kidney was markedly increased and had free ribosomes, developed Golgi apparatus and rough endoplasmic reticulum. 3. At the 30 days, the section of the glomeruli were more enlarged in the left kidney than in the right. 4. At the 20 day, the nuclear section of the podocytes were markedly enlarged in the right kidney, but those of the left kidney were diminished. The mitochondrial section of the podocytes were prominently increased in the right kidney. 5. The nuclear section of the parietal layer lining cells was no significant change in the right kidney. That of the left kidney was increased at the 20 days and decreased at the 40 days. The nuclear section of glomerular endothelium of the left kidney increased earlier than the right. 6. In the morphometry of the control kidney, the section areas, long and short diameters, the nuclear section, the mitochondrial section of the proximal tubule cells, and the changes of those were more large in the right kidney than in the left. 7. The luminal secretory vesicles and peroxisomes of the left kidney were more than the right at the 20 days. The increase of mitochodrial section in the proximal tubule cells of the left kidney was more prominent than the right. The large cytoplasmic vacuoles were more prominent in the left kidney than in the right. 8. The thickness of cytoplasm and brush border was more thick in the control left kidney than in the control right. The change of cytoplasmic thickness of the left kidney was increased earlier than in the right and both kineys were increased in the thickness of brush border at the 30 days.
이경태,정민길,최호림,Lee, Kyung-Tae,Jeong, Min-Gil,Choi, Ho-Lim 대한전기학회 2017 전기학회논문지 Vol.66 No.1
We propose a switching control scheme for the control of a ball and beam system. It was reported in [4] that a ball and beam system is a nonlinear system which has an ill-defined relative degree. So, the traditional control approaches have been mostly either Jacobian-based control or approximate input-output linearized control in nature. In this paper, motivated by [7], we combine these two traditional control approaches and operate each controller via a pre-designed switching logic so that the improved control result can be obtained without any excessive use of control input. Switching algorithm is developed based on both analysis and actual experimental observation. We verify the effectiveness of our proposed controller via actual experimental results.
이경태,임형주,김상욱,안윤호,윤여동,Lee Kyung-Tae,Lim Hyung-Joo,Kim Sang-Wook,Ahn Yun-Ho,Youn Yeo-Dong 한국디지털콘텐츠학회 2002 한국디지털콘텐츠학회논문지 Vol.3 No.1
Radiologic images are widely used in hospitals for diagnosing and treating patients' diseases. The radiologist accurately reads radiologic images, and thus helps diagnose patients correctly. The number of radiologists is much smaller than is necessary, however. In some small or rural hospitals, there are no radiologists residing there. In these cases, correct diagnosis and treatment are infeasible. Also, radiologists are not resident at hospitals all day long. Thus, emergency patients would suffer from the absence of radiologists at night. XRay21 Inc. and Data & Knowledge Engineering Lab. at Kangwon National University have been working together since 2000 in order to alleviate the problems above. Currently, the advances of the computer and network technology make it possible to connect a lot of radiologists and hospitals together through the Internet. By fully utilizing the Internet environment, we have developed an Internet-based medical diagnosis system, thus permitting remote diagnosis of radiologic images. This paper presents the technical experiences obtained in developing the system.