비신생물성 질환에 대한 췌십이지장 절제술의 안정성 및 수술 후 삶의 질에 대한 평가

은영아(Young A Eun),김상걸(Sang Geol Kim),윤혁진(Hyuk Jin Yun),김종렬(Jong Yeol Kim),김갑철(Gab Chul Kim),염현규(Hyun Kyu Ryeom),김성희(Sung Hi Kim),황윤진(Yun Jin Hwang),윤영국(Young Kook Yun) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.1

Purpose: Pancreaticoduodenectomy for mass-like lesions that are suspicious of malignancy sometimes reveals only nonneoplastic disease, especially in those cases where adequate tissues for biopsy are unavailable. In this study, we evaluated the outcomes and quality of life (QOL) after pancreaticoduodenectomy for treating nonneoplastic disease. Methods: The clinical data of 28 patients who underwent pancreaticoduodenectomy for nonneoplatic disease and trauma from Jan. 1992 to Feb. 2006 were reviewed retrospectively. The QOL was evaluated using the FACT-Hep questionnaire. The patients who underwent laparoscopic cholecystectomy for benign gallbladder disease were utilized as the control group. Results: 13.8% (28/203) of all the pancreaticoduodenectomized patients had nonneoplatic disease and trauma. Male patients were predominant (25/28) and all the trauma patients were male. The mean age was 48 (23∼72) years old. The indications for surgery included lesions suspicious for malignancy (16 cases), pancreaticoduodenal artery aneurysm (1 case), and pancreatoduodenal injury (11 cases). The histologic findings of the nonneoplastic lesions revealed benign inflammation of the bile duct (6 cases), chronic pancreatitis (8 cases), pancreatic pseudocyst (1 case), and fibrosis of the Ampulla of Vater (1 case). No surgical mortality occurred. However, the trauma patients group had higher morbidity (72.7% Vs 23.5%, respectively, P=0.01) and a longer hospital stay (68.0 days Vs 32.6 days, respectively, P=0.02) after surgery compared to the nonneoplastic disease patient group. The QOL of the patient who underwent pancreaticoduodenectomy for nonneoplatic disease was not different from that of the control group. Conclusion: Since pancreaticoduodenectomy for nonneoplastic disease was safe and the QOL of the patients was acceptable, it should be performed more often when malignancies can not be excluded from the differential diagnosis.

타이치 운동이 혈압과 심폐기능에 미치는 영향에 대한 논문 분석

은영,이혜영,최정현,이은옥,Eun, Young,Lee, Hea-Young,Choi, Jung-Hyun,Lee, Eun-Ok 대한근관절건강학회 2005 근관절건강학회지 Vol.12 No.2

Purpose: The purpose of this study is to analyze the effect of Tai Chi exercise on Cardiorespiratory function and to identify directions for future research. Method: 19 articles from Medline search of english journals(1981-2004) and 2 from Korean nursing journals were surveyed. The contents analysis were focused on outcome measures and relative factors regarding cardiopulmonary function. Results: There are 21 articles including 8 articles with quasi experimental design, 7 articles with randomized controlled design and 6 articles with comparative non experimental research design. The major subjects of research were older adults, but hypertensive patients, cardiac rehabilitative patient, and osteoarthritic patient also included. The major style of Tai Chi was Yang style with 108-form. The duration of Tai Chi exercise was from 12weeks to 13.2 years in comparative non experimental studies, but 6 weeks to 16weeks in randomized controlled experimental studies. The most effective duration for cardiopulmonary function was over 16weeks. The variables for cardiopulmonary function were blood pressure, heart rate and cardiopulmonary function via $VO_2$ max(ml/kg/min). To reduce the blood pressure in the result was found in 2 articles, to reduce the heart beat was found in 1 article, to improve the cardiopulmonary function via $VO_2$ max in results were found in 7 articles(73%) among 11 articles. Conclusion: The Tai Chi exercise over 16weeks improves the cardiopulmonary function. It is suggested that to verify the effect of Tai Chi on cardiopulmonary function, the difference of gender, age, health status will be identified through repeated experiments.

자기통제의 개념 분석

은영,이인숙,이경숙,송경자,최은옥,서순림,양영희,박영임,구미옥,김성재,김인자,이은남,박송자,이동숙,이은옥,Eun, Young,Lee, In-Sook,Lee, Keung-Sook,Song, Keung-Ja,Choi, Eun-Ok,Shu, Soon-Rim,Yang, Young-Hee,Park, Young-Im,Gu, Mee-Ok,Kim, Sung-Jae,Kim 한국간호과학회 1999 Journal of Korean Academy of Nursing Vol.29 No.4

Today human needs for health promotion and maintenance are increasing. The nursing profession as a great responsibility to develop the knowledge for helping clients to practice good health behavior under self-control. But there are few studies about the concept of self-control, or the operational definition of self-control. The purpose of this study was to analyze and clarify the meaning of the concept of self-control. This study used Walker and Avant's process of concept analysis. Antecedents of self control consist of 1) perception of the conflict situation to change his or her behavior ; 2) perception of self as the causes of the barrier for a certain behavior ; 3) internal standard or belief such as self-efficacy and learned resourcefulness ; 4) internal motivation for change of behavior. Critical attributes of self-control were 1) goal-orientation ; 2) self-decision ; 3) time sequence ; 4) effort ; 5) possibility of being learned ; 6) individuality ; 7) social desirability. Consequences occurring as a results of self-control consist of 1) achievement of the controlled behavior whose purposes were planned ; 2) enhancement of the internal standard such as self-efficacy and learned resourcefulness ; 3) eventual elevation of physical and emotional wellness. Therefore, this concept is defined as a cognitive behavior which is attempted by his or her decision when one is confronted with the conflict situation, which is characterized by being changed by time, learned by effort and individual characteristics. One is taking such behavior with the perception of self as the causative barrier for a certain behavior, planning a specific objective for a certain behavior which demands self sacrifice, supplies the internal reward, is socially desirable with the internal standard of self-efficacy and learned resourcefulness and environmental factors.

흰쥐 대뇌피질 절편에서 허혈에 의한 Norepinephrine 유리에 있어서 Nitric Oxide의 영향

은영아,김동찬,조규박,김기원,Eun, Young-Ah,Kim, Dong-Chan,Cho, Kyu-Park,Kim, Kee-Won 대한약리학회 1997 The Korean Journal of Physiology & Pharmacology Vol.1 No.6

It has been generally accepted that glutamate mediates the ischemic brain damage, excitotoxicity, and induces release of neurotransmitters, including norepinephrine(NE), in ischemic milieu. In the present study, the role of nitric oxide(NO) in the ischemia-induced $[^3H]norepinephrine([^3H]NE)$ release from cortex slices of the rat was examined. Ischemia, deprivation of oxygen and glucose from $Mg^{2+}-free$ artificial cerebrospinal fluid, induced significant release of $[^3H]NE$ from cortex slices. This ischemia-induced $[^3H]NE$ release was significantly attenuated by glutamatergic neurotransmission modifiers. $N^G-nitro-L-arginine$ methyl ester(L-NAME), $N^G-monomethyl-L-arginine$ (L-NMMA) or 7-nitroindazole, nitric oxide synthase inhibitors attenuated the ischemia-evoked $[^3H]NE$ release. Hemoglobin, a NO chelator, and 5, 5- dimethyl-L-pyrroline-N-oxide(DMPO), an electron spin trap, inhibited $[^3H]NE$ release dose-dependently. Ischemia-evoked $[^3H]NE$ release was inhibited by methylene blue, a soluble guanylate cyclase inhibitor, and potentiated by 8-bromo-cGMP, a cell permeable cGMP analog, zaprinast, a cGMP phosphodiesterase inhibitor, and S-nitroso-N-acetylpenicillamine (SNAP), a nitric oxide generator. These results suggest that the ischemia-evoked $[^3H]NE$ release is mediated by NMDA receptors, and activation of NO system is involved.

한약처방제의 인체 위암 세포주에 대한 세포독성 효과에 관한 연구

김은해,은영아,강봉주,성현제,박갑주,Kim, Eun-Hae,Eun, Young-Ah,Kang, Bong-Joo,Sung, Hyun-Jae,Park, Kap-Joo 한국생약학회 1997 생약학회지 Vol.28 No.4

ln order to search for antigastric cancer agents from Korean traditional prescriptions. We selected 41 traditional prescriptions, based on a review of the Korean traditional medicine books. Both boiling water and methanol extracts were tested, by means of the Sulforhodamine B (SRB) protein assay. Six of the 41 water extracts; #3, #34, #35, #38, #40, #41 showed efficacy against gastric cancer cell (AGS: Human gastric carcinoma, ATCC HTB 103). #3 inhibited 50% cancer cell growth1 at the concentration of $152\;{\mu}g/ml$, #34, #35, #38, #40 and #41 inhibited 50% cancer cell growth at the concentration of $145\;{\mu}g/ml$, $129\;{\mu}g/ml$, $173\;{\mu}g/ml$, $10\;{\mu}g/ml$ and $19\;{\mu}g/ml$ respectively. Ten of the 41 methanol extracts; #1, #3, #32, #33, #35, #36, #37, #38, #41 were active. #1 inhibited 50% cancer cell growth at the concentration of $206\;{\mu}g/ml$, #3, #32, #33, #35, #36, #37, 738, #40, #41 inhibited 50% cancer cell growth at the concentration of $133\;{\mu}g/ml$, $159\;{\mu}g/ml$, $199\;{\mu}g/ml$, $147\;{\mu}g/ml$, $113\;{\mu}g/ml$, $187\;{\mu}g/ml$, $130\;{\mu}g/ml$, $9\;{\mu}g/ml$, $15\;{\mu}g/ml$ respectively. Prescription #3, #35, #38, #40, #41 were also interesting because both methanol and water extracts were active.

조기 유방암으로 변형 근치적 절제술 후 단독국소재발한 환자의 예후

이승재(Seung Jae Lee),황승욱(Seung Oook Hwang),정진향(Jin Hyang Jung),박호용(Ho Yong Park),이준혁(Jun Hyuk Lee),은영아(Young A Eun) 대한외과학회 2009 Annals of Surgical Treatment and Research(ASRT) Vol.76 No.5

Purpose: Isolated local recurrence (ILR) after mastectomy is associated with increased risk of cancer-specific survival. This study evaluated the long-term survival and prognostic factors after ILR. Methods: Between January 1988 and December 2004, 1,169 patients with early breast cancer (stage Ⅰ or Ⅱ) were treated with modified radical mastectomy at Kyungpook hospital. Retrospectively, 40 patients with isolated local recurrence (ILR) were found by medical records and we investigated their clinicopathologic factors and conducted analyses of prognostic factors, calculated overall survival, and relapse-free survival. Results: The median follow-up times after initial operation and ILR were each 91 (range, 18∼219) months and 40 (range, 1∼205) months. There were 18 patients of 2nd recurrence and 15 expired by distant metastasis. The overall survivals at 5 years and 10 years after ILR were 65% and 49%. The relapse-free survivals at 5 years and 10 years after ILR were 54% and 29%. After 2nd recurrence, the mean survival time was 21 months and the 3-year overall survival rate was 21%. By univariate and multivariate analyses, the time interval between initial operation and ILR was only statistically significant independent prognostic factor of overall survival after ILR. The 10 year-overall survival rates of ≤24 months and >24 months to ILR were each 26% and 70%. There was no independent prognostic factor of relapse-free survival after ILR. Conclusion: For patients who developed isolated local recurrence after modified radical mastectomy for early breast cancer, shorter time interval to ILR is a poor prognostic factor of overall survival after ILR.

일지역 노인의 관절 건강 상태

은영(Eun Young),김은심(Kim Eun-Shim),강영실(Kang Young-Sil),권인수(Kwon In-Soo),오현숙(Oh Hyun-Sook),구미옥(Gu Mee-Ock) 기본간호학회 2004 기본간호학회지 Vol.11 No.2

상급종합병원과 종합병원의 근거기반 임상간호실무지침의 활용도

은영 ( Eun Young ),전미양 ( Jeon Mi Yang ),구미옥 ( Gu Mee Ock ),조용애 ( Cho Young Ae ),김정연 ( Kim Jung Yeon ),권정순 ( Kwon Jeong Soon ),김경숙 ( Kim Kyeong Sug ) 병원간호사회 2021 임상간호연구 Vol.27 No.3

Purpose: The purpose of this study was to investigate the actual utilization of clinical practice guidelines developed by Hospital Nurses Association. Methods: The subjects were 70 nurses who were in charge of guideline distributions in 70 advanced general hospital and general hospitals with 500 beds or more nationwide. Data were collected between June and August, 2020 by mail (return rate: 88.6%). Data were analyzed using descriptive statistics, t-test, and ANOVA with SPSS/WIN 24.0. Results: Among the clinical practice guidelines developed by Hospital Nurses Association, 72.9~90.1% were placed with book and electronic file in nursing department and 24.3~35.8% were placed with book and electronic file in each nursing unit at hospital. The average number of utilized clinical practice guidelines were 3.96±3.88, and average score of guideline utilization was score 2.85±0.79 which means ‘use sometimes’. Conclusion: To improve the distribution and utilization of the clinical practice guidelines, it is necessary to enhance the recognition of values of evidence based nursing practice targeting head of nursing department and to stimulate the distribution and utilization of the clinical practice guidelines using diverse education programs for staff nurses.

노인의 관절 건강증진 프로그램 효과

은영(Eun Young),강영실(Kang Young-Sil),김은심(Kim Eun-Shim),권인수(Kwon In-Soo),오현숙(Oh Hyun-Sook),구미옥(Gu Mee-Ock) 기본간호학회 2005 기본간호학회지 Vol.12 No.2

국내 상급종합병원과 종합병원에서의 정맥주입간호실무지침에 대한 태도와 확산정도

은영(Young Eun),구미옥(Mee Ok Gu),조용애(Young Ae Cho),김신미(Shin Mi Kim),정재심(Jae Shim Jeong),권정순(Jeong Soon Kwon),유정숙(Cheong Suk Yoo),정영선(Young Sun Jeong),정인숙(In Sook Jung),김경숙(Kyeong Sug Kim)이선희(Seon Heui Lee 한국근거기반간호학회 2014 근거와 간호 Vol.2 No.1

Purpose: This study was conducted to investigate the level of attitudes to and diffusion of Intravenous infusion nursing practice guideline in advanced general hospitals and general hospitals in Korea. Methods: The subjects were 41 nurses who were in charge of guideline diffusion in 41 advanced general hospitals and general hospitals. Data were collected between September 25 and November 2, 2014 by mail (return rates: 68.3 %). Data were analyzed using descriptive statistics, t-test, and ANOVA with SPSS/WIN 18.0. Results: The average attitude score of guideline among nurses in charge of guideline diffusion were 3.98±0.38 (range 1~5). The average guideline diffusion score and levels of diffusion was 2.26±1.39 (level of “persuasion of nursing knowledge”) for staff nurses, 3.05±0.86 (level of “use sometimes”) for nurses in charge of guideline diffusion, 2.87±0.78 (level of “use sometimes”) for nurse directors. 41.4 % of nursing divisions in 41 hospitals reviewed the intravenous infusion nursing practice guideline, educated the guideline to nurses, and implemented the guideline in clinical practice for guideline diffusion. Conclusion: Study findings indicate that nurses in charge of intravenous infusion nursing practice guideline in hospitals had positive attitude for guideline. The levels of guideline diffusion in hospitals was “persuasion of nursing knowledge” to “use sometimes”. Therefore, the strategies for promoting the diffusion and implementation of guideline in clinical practice in the level of nursing division is needed. Further study of outcome evaluation of guideline implementation will be needed.