태양열 집열판에 작용하는 풍압력 평가

윤현재(Yoon, Hyun-Jae),유장열(You, Jang-Youl),유기표(You, Ki-Pyo Kim),김영문(Kim, Young-Moon) 대한건축학회 2010 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.30 No.1(구조계)

Micro-block Stacking 방법으로 제작한 집적형 Triplexer 제작 및 특성 측정

윤현재,김진원,Yoon, Hyun-Jae,Kim, Jin-Won 한국광학회 2012 한국광학회지 Vol.23 No.5

본 논문에서는 정밀 세라믹 부품을 이용한 MBS(Micro-Block Stacking) 방법으로 1550 nm 파장의 아날로그 신호 수신과 1310nm/1490nm 파장의 디지털 신호 송, 수신이 가능한 8 pin mini DIL 형태의 집적형 Triplexer를 제작하였다. 제작된 전체 어셈블리는 $5.40mm{\times}2.15mm{\times}1.05mm$ 크기로 통신용 광모듈 국제 표준인 MSA(Multi Source Agreement) 규격의 SFP(Small Form Pluggable) 광모듈 제작이 가능하다. 자동 능동 광정렬 장비를 사용하여 제작된 집적형 Triplexer를 단일모드 광섬유에 광정렬하였을 때, 1310 nm 송신부 최대 광출력이 -14.5 dBm이었고, 송신부에 의하여 위치가 자동 정렬된 1550 nm와 1490 nm 수신부 수신감도는 각각 0.83 A/W, 0.73 A/W로 단거리 통신에 적용 가능한 값을 얻었다. In this paper, we have fabricated by means of the "Micro-Block Stacking (MBS)" method the 8 pin mini DIL integrated Triplexer, which can transmit CATV and voice/data at the same time in a single fiber. Our MBS technique is a novel scheme of compact optical module packaging which secures precision positioning of the components on the optical beam path by prefixed stacks of ceramic blocks. The subassembly in which a laser diode, two receiver photodiodes, two WDM filters, and four micro lenses are integrated is only $5.40mm{\times}2.15mm{\times}1.05mm$ in size. As the Triplexer is aligned to the single mode fiber, the transmitter power of -14.5 dBm and the receiver sensitivities of 0.83 A/W, 0.73 A/W for 1550 nm, 1490 nm, respectively are obtained.

통신용 광모듈 패키징 기술

윤현재(Hyun-Jae Yoon) 한국통신학회 2009 한국통신학회 기타 간행물 Vol.2009 No.12

Micro Block Stacking 방법으로 제작한 집적형 단일모드 외부 공진 레이저

윤현재,Yoon, Hyun-Jae 한국광학회 2008 한국광학회지 Vol.19 No.2

Micro-Block Stacking(MBS) 방법으로 1550nm FP-LD와 박막 필터, 마이크로 볼 렌즈를 사용하여 집적형 외부 공진기 레이저를 제작하였다. 제작한 집적형 외부 공진기 레이저 모듈 크기는 $2.0{\times}2.1{\times}0.7\;mm^3$이었으며 TO-CAN 형태로 패키징하였다. 투과율이 1.8%인 박막 필터를 사용한 집적형 외부 공진기 레이저의 경우 광출력이 -27.1 dBm이고 SMSR이 31.7 dB인 양호한 단일모드 레이저 특성을 얻을 수 있었다. The integrated external cavity laser has been fabricated with a 1550 nm FP-LD, an optical filter, a micro ball lens and accurate ceramic blocks using a micro-block stacking (MBS) technique. The integrated external cavity laser module whose size is only $2.0{\times}2.1{\times}0.7\;mm^3$ has been mounted on the TO-CAN package. For the case of the 1.8% transmission filter, the single mode characteristic has been obtained with the optical power of -27.1 dBm and the SMSR of 31.7 dB.

광 HDMI 인터페이스용 2채널 광송신기 광학 설계

윤현재,강현서,Yoon, Hyun-Jae,Kang, Hyun-Seo 한국광학회 2015 한국광학회지 Vol.26 No.5

본 논문에서는 code V 시뮬레이터를 이용하여 광 HDMI 인터페이스에 적용하기 위한 집적형 2채널 TO 구조 광송신기의 광학계 설계를 하였다. 제안된 집적형 2채널 TO 구조 광송신기는 지름의 6.4 mm인 하나의 8 pin TO-CAN 패키지 안에 2개의 VCSEL을 평행하게 부착하고 그 위에 반구(hemisphere) 렌즈가 부착된 직육면체 모양($1mm(H){\times}2mm(W){\times}4mm(D)$)의 렌즈필터 블록 (lens filter block) 을 올려놓은 구조이다. 집적형 2채널 TO 구조 광송신기 제작 시 1060 nm/1270 nm와 1330 nm/1550 nm로 두 개 파장씩 묶어 TO-CAN 형태로 제작하므로, 이들 파장 조합에서 반구 렌즈의 지름은 0.6 mm, 볼 렌즈와 렌즈 필터 간격(L)은 파장 1060 nm/1270 nm 조합의 경우 1.7 mm, 파장 1330 nm/1550 nm 조합의 경우 2.0 mm일 때 최적의 결과를 얻을 수 있었다. 이때 렌즈필터 블록의 초점거리($f_0$)는 1060 nm, 1270 nm, 1330 nm, 1550 nm 파장에 대하여 0.351 mm, 0.354 mm, 0.355 mm, 0.359 mm이었으며 렌즈 필터 블록과 볼 렌즈를 통과한 빛의 초점 위치(F)는 파장 1060 nm/1270 nm 조합의 경우 0.62 mm, 파장 1330 nm/1550 nm 조합의 경우 0.60 mm ~ 0.66 mm이었다. In this paper we design the optical system for an integrated two-channel TO-type optical transmitter to apply the HDMI interface using the code V simulator. The proposed integrated two-channel optical transmitter has two VCSELs attached in parallel on an 8-pin TO-CAN package, on top of which is a lens filter block ($1mm{\times}2mm{\times}4mm$) composed of hemispherical lenses and WDM filters. Considering two-channel transmitters manufactured with wavelength combinations of 1060nm/1270nm and 1330nm/1550nm, we obtain the optimum value of the diameter of the hemispherical lens as 0.6 mm for both combinations, and the distances L between the lens filter block and ball lens as 1.7 mm and 2.0 mm for the 1060nm/1270nm and 1330nm/1550nm wavelength combinations, respectively. At this time, the focal length f0 of the lens filter blocks for wavelengths of 1060, 1270, 1330, and 1550 nm are 0.351, 0.354, 0.355, and 0.359 mm, respectively, and the focal lengths F of light passing through the lens filter block and ball lens are 0.62 mm for 1060nm/1270nm and 0.60-0.66 mm for 1330nm/1550nm wavelength combinations.

MBS 방법으로 제작한 집적형 Triplexer의 광학 설계

윤현재,김종혁,Yoon, Hyun-Jae,Kim, Jong-Hyuk 한국광학회 2011 한국광학회지 Vol.22 No.4

본 논문에서는 FTTH(fiber to the home) 망에 사용되는 $1.55{\mu}m$ 파장의 아날로그 신호 수신과 $1.31{\mu}m/1.49{\mu}m$ 파장의 디지털 신호 송, 수신이 가능한 집적형 Triplexer를 설계하였다. 이 집적형 Triplexer는 세라믹 재질로 정밀 제작한 서브마운트, 레이저 다이오드 홀더, 포토다이오드 홀더를 이용하여 마이크로 볼렌즈, WDM 필터, FP-LD, PIN-PD 등 광부품을 광 축에 자동으로 정렬시키는 micro block stacking 방법으로 제작 가능한 구조로 설계하였으며 code V 소프트웨어를 이용하여 각 부품의 제작 공차와 조립 공차에 따른 초점의 위치 변위를 분석하였다. 공차 분석 결과 송신부에서 초점의 위치 변화에 가장 큰 영향을 주는 것은 LD spot의 위치 변위로 x, y, z 방향으로 각각 ${\pm}25{\mu}m$, ${\pm}25{\mu}m$, ${\pm}30{\mu}m$ 움직였을 때 초점이 최대 $72{\mu}m$ 이동하였으며 수신부의 경우 0.8mm 볼렌즈(아날로그 신호 수신부)와 마이크로 볼 렌즈(디지털 신호 수신부) 위치 변화가 가장 큰 영향을 주는 것을 알 수 있었으며 디지털 신호 수신부의 경우 마이크로 볼 렌즈가 x, y, z 방향으로 각각 ${\pm}55{\mu}m$, ${\pm}5{\mu}m$, ${\pm}55{\mu}m$ 움직였을 때 초점이 최대 $55{\mu}m$ 이동하였다. In this paper, we have designed an integrated triplexer which is the basic component for a FTTH(Fiber To The Home) system which can transmit CATV and voice/data at the same time in a single fiber. The integrated triplexer can be fabricated with a novel technique of "Micro-Block Stacking (MBS)" method which automatically aligns the optical components in the optical beam pass using accurate ceramic holders. We analyze the displacement of the optical focus according to the tolerances of the component dimensions and the assembly process using code V simulator. For the transmitter, the most serious shift of the focal points is caused by the displacements of the LD spot. So the focal point moves up to $72{\mu}m$ from the center point for ${\pm}25{\mu}m$, ${\pm}25{\mu}m$, ${\pm}30{\mu}m$ displacements. For the receiver the most serious shift of the focal points is caused by the displacements of a 0.8mm ball lens (for the analog receiving part) and a micro ball lens (for the digital receiving part), and the focal point moves up to $55{\mu}$ for ${\pm}55{\mu}m$, ${\pm}5{\mu}m$, ${\pm}55{\mu}m$ micro ball lens displacements.

위치 변화에 따른 연성 막구조물의 풍진동 응답연구

정재용(Jeong Jae-Yong),윤현재(Yoon Hyun-Jae),유기표(You Ki-Pyo),김영문(Kim Young-Moon) 대한건축학회 2009 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.29 No.1(구조계)

In this paper, With relevant literatures about wind tunnel similarity law of tensioned membrane structure. First, from selected materials to manufacture the model and because modeling selects membrane structure water of umbrella style hanging banner form that is using much recently ductility keeping form just according to wind tunnel law of similarity model manufacture. Does not change its form, under the conditions , around the model ,respectively Evenly imposed on two pretension, using the BLWT (Eiffel type) wind tunnel of CBNU Division of Architectural and Urban Engineering for their flexibility wind vibration responsion test. Observation of the existence of significant differences in pretension circumstances, the wind speed at different umbrella membrane structure under the conditions of X-axis, Y-axis wind vibration response, through drawing contour lines, analysis tensioned membrane structure by the wind vibration changes of each location to explore the comparison in different pretension, different wind speeds, the membrane structure of the wind vibration response (displacement) response. For the future to engage in field measurements and numerical wind tunnel simulation analyse of similar form model, provide an effective basis experimental evidence is far-reaching significance.

한국인 가족성 고콜레스테롤혈증 진료에 대한 2022년 합의안

이찬주 ( Chan Joo Lee ),윤민재 ( Minjae Yoon ),강현재 ( Hyun-jae Kang ),김병진 ( Byung Jin Kim ),최성희 ( Sung Hee Choi ),정인경 ( In-kyung Jeong ),이상학 ( Sang-hak Lee ) 대한내과학회 2022 대한내과학회지 Vol.97 No.6

Familial hypercholesterolemia (FH) is the most common monogenic disorder. Due to the marked elevation of cardiovascular risk, the early detection, diagnosis, and proper management of this disorder are critical. Herein, the 2022 Korean guidance on this disease is presented. Clinical features include severely elevated low-density lipoprotein cholesterol (LDL-C) levels, tendon xanthomas, and premature coronary artery disease. Clinical diagnostic criteria include clinical findings, family history, or pathogenic mutations in the LDLR, APOB, or PCSK9. Proper suspicion of individuals with typical characteristics is essential for screening. Cascade screening is known to be the most efficient diagnostic approach. Early initiation of lipid-lowering therapy and the control of other risk factors are important. The first-line pharmacological treatment is statins, followed by ezetimibe, and PCSK9 inhibitors as required. The ideal treatment targets are 50% reduction and < 70 or < 55 mg/dL (in the presence of vascular disease) of LDL-C, although less strict targets are frequently used. Homozygous FH is characterized by untreated LDL-C > 500 mg/dL, xanthoma since childhood, and family history. In children, the diagnosis is made with criteria, including items largely similar to those of adults. In women, lipid-lowering agents need to be discontinued before conception. (Korean J Med 2022;97:339-352)

산지별 더덕 추출물의 폐암 및 난소암에 대한 항암 효능

조영락 ( Young Rak Cho ),김수현 ( Soo Hyeon Kim ),윤현재 ( Hyun Jae Yoon ),홍삼열 ( Sam Yeol Hong ),고희영 ( Hee Young Ko ),박은희 ( Eun Hee Park ),김명동 ( Myoung Dong Kim ),서동완 ( Dong Wan Seo ) 한국산업식품공학회 2011 산업 식품공학 Vol.15 No.1

Codonopsis lanceolata L. (Campanulaceae) has long been used in traditional Korean medicine to treat bronchitis, cough, and inflammatory diseases, however, the efficacy of anti-tumor activities remains to be defined. In this study the effects of Codonopsis lanceolata (C. lanceolata) on proliferation, migration and adhesion in lung (A549, H1299) and ovarian cancer (SKOV-3) cells were investigated. To assess and compare the pharmacological effects and production places of C. lanceolata, the ethanolic extracts of C. lanceolata from different places in Korea (Hongseong, Yecheon, Yeongwol, Yanggu, Gangjin, and Hoengseong) were prepared. The extract from Hoengseong county did have only marginal anti-proliferative activity in all the cell lines tested, however, other extracts had little or no effect on cell proliferation. The extracts from Hongseong, Gangjin or Hoengseong county had partial anti-migratory activity in lung cancer cells, but not in ovarian cancer cells. In addition, the extract from Hoengseong county had partial anti-adhesive activity in ovarian cancer cells, however, other extracts did not affect cell adhesion in both lung and ovarian cancer cells. Taken together, these findings provide the first description of anti-tumor efficacy of C. lanceolata from different production places in Korea, and suggest that C. lanceolata from Hoengseong county may have therapeutic potential in lung and ovarian cancers.

Tissue Inhibitor of Metalloproteinases-2와 Endostatin의 혈관신생 제어 효능 평가

김수현(Soo Hyeon Kim),조영락(Young-Rak Cho),윤현재(Hyun Jae Yoon),고희영(Hee-Young Ko),김평현(Pyeung-Hyeun Kim),서동완(Dong-Wan Seo) 대한약학회 2010 약학회지 Vol.54 No.6

Therapeutic manipulation of angiogenesis, the formation of new vascular sprouts from existing capillaries, is one of the promising strategies for treatment of human diseases such as cancer, arthritis, and cardiovascular disorder. In the present study, we examined the effects and molecular mechanism of tissue inhibitor of metalloproteinases-2 (TIMP-2) and endostatin on fibroblast growth factor-2 (FGF-2)-stimulated endothelial cell proliferation, migration and adhesion in vitro, and angiogenesis in vivo. TIMP-2 and endostatin showed potent anti-angiogenic activity in vitro and in vivo. These effects appear to be mediated through different angiogenic signaling pathways. Collectively, our findings demonstrate that TIMP-2 and endostatin strongly inhibit FGF-2-induced angiogenic responses, and the establishment of fast and reproducible evaluation system in vitro and in vivo for the development of anti-angiogenic biomaterials and therapeutics.