구강암으로 변연골 절제술 시행한 환자를 임플란트 보조 국소의치로 수복한 증례

윤영석,한동후,김형준,김지환,Yoon, Young-Suk,Han, Dong-Hoo,Kim, Hyung-Joon,Kim, Jee Hwan 대한치과보철학회 2016 대한치과보철학회지 Vol.54 No.3

하악골의 결손은 선천적 기형, 외상, 골수염, 종양 절제술 등에 의하여 초래될 수 있는데, 이중 결손부위가 큰 경우는 주로 종양절제술에 의한 결손이다. 악골 결손 부위가 커질수록 저작, 연하, 교합, 발음 등에 큰 지장을 초래하게 되며 심미적으로도 불량하여 일상생활에 많은 불편을 주게 된다. 하악골이 절제된 후 그 자리에 완전히 재생되는 경우는 희박하며 인공적으로 재건해 주어야 한다 일반적으로 자가골 이식을 이용한 재건술을 시행하며, 통상적인 부분의치 혹은 총의치를 시행하거나, 지지할 수 있는 골을 얻은 상태에서 임플란트 고정성 보철, 임플란트 보조 국소의치 혹은 피개의치 등을 시행할 수 있다. 본 증례는 2004년 2월 25일, 편평세포암종 pT1N0M0, stage I로 진단 받고 구강악안면외과에서 동년 3월, 하악 좌측 부위 COMMANDO 수술(combined mandibulectomy and neck dissection operation), 광범위 절제술(wide excision), 하악골 변연절제술(marginal mandibulectomy), 견갑 설골 상부 경부청소술(supraomohyoid neck dissection, SOHND), 시행받은 환자를 하악 좌측 중절치, 하악 좌측 제3대구치 부위에 임플란트 식립하여 임플란트 보조 국소의치로 수복하였고 충분한 피개와 임플란트로의 적절한 교합력 분산을 통해 통상적인 국소의치보다 더 이로운 지지, 유지, 안정을 얻을 수 있었다. 현재까지 경과 관찰 기간은 4년 정도 되었으며, 하악 좌측 제3대구치 부위에는 주위골의 흡수양상이 관찰되어 주기적인 검진이 필요한 상황이다. Mandible defects could be caused by congenital malformations, trauma, osteomyelitis, tumor resection. If large areas are included for reconstruction, those are primarily due to tumor resection defects. The large jaw defect results in a problem about mastication, swallowing, occlusion and phonetics, and poor esthetics causes a lot of inconvenience in daily life. It is almost impossible to be a part underwent mandibular resection completely reproduced, should be rebuilt artificially. This case is of a patient who was diagnosed with squamous cell carcinoma pT1N0M0, stage I in February 2004 and received surgery (combined mandibulectomy and neck dissection operation (COMMANDO) in oromaxillofacial surgery) in March 2004, by implant assisted removable partial denture. We could obtain good retention and stability through sufficient coverage and implant holding. Follow up period was about four years. Mandibular left third molar regions have been observed to have resorption of surrounding bone, and periodic check-ups are necessary conditions.

본태성 고혈압 환자에서 혈소판내 유리칼슘의 변화

윤영석(Young Suk Yoon),구완서(Wan Suh Koo),박인석(In Suk Park),김석영(Suk Young Kim),최의진(Euy Jin Choi),방병기(Byung Kee Bang) 대한내과학회 1991 대한내과학회지 Vol.41 No.2

N/A To investigate a possible association between intracellular free calcium and blood pressure in normotensive subjects and patients with essential hypertension, intraplatelet free calcium was measured with intracellularly trapped fluorescent indicator Fura 2-AM. The results were as follows: 1) Intraplatelet free calcium levels were significantly higher in patients with essential hypertension than in normotensive subjects (222.4±58.0 vs. 119.6±10.9 nM; p < 0.0001). 2) There was a close correlation between the intraplatelet free calcium levels and the systolic, diastolic and mean blood pressure (n=45; r=0.817 for SBP, 0.728 for DBP, 0.800 for MBP; p<0.0001, respectively). 3) Antihypertensive treatment with calcium channel blookers or beta-blockers resulted in a reduction in both blood pressure and intraplatelet free calcium(p<0.0001). 4) There was a significant correlation between intraplatelet free calcium and serum cholesterol concentration (r=0.462, p<0.05). Based on the above findings, there was a close correlation between the free calcium level in platelets and blood pressure, and the serum cholesterol concentrations. Antihypertensive treatment with calcium channel blockers or beta blockers resulted in a reduction in free calcium, which correlated with the fall in blood pressure.

생체 신장이식에서 이식신 생존율에 미치는 HLA 적합성의 영향

윤영석(Young Suk Yoon),방병기(Byung Kee Bang),김원일(Won Il Kim),고용복(Yong Bock Koh) 대한내과학회 1992 대한내과학회지 Vol.43 No.4

N/A Background & Methods: HLA matching continues to stand out as an important factor in renal transplantation despite improvement in immunosuppression. Therefore, we have analyzed 478 first living renal transplants who had been treated with Aza (n=68) or CsA (n=410) between April 1979 and March 1991 to determine the beneficial effect on graft survival of HLA antigens matching. Results: CsA signiftcantly improved kidney graft survival by 17% at 5years as compared with Aza group (77% vs. 65%; p=0.0252), Matching for the HLA-A+B significantly improved kidney graft survival, which the difference between 1 mismatched group and 2mismatehed group was 27% at 5years (67% vs. 40% p=0.0436) in the Aza group, but not in the CsA group, An impressive 34% difference in kidney graft survival was observed at 5years between the CsA-treated patients who received 0 and 2HLA-DR mismatches (83% vs. 49%; p=0,00001), but not between Aza-treated patients. The 5-year kidney graft survival in the 1 B+ DR mismatched CsA group was 86d, which was significantly different from 64Fp survival in the 4 B+DR mismatched group (p=0.0105), but not in the Aza group. The effect of HLA -A+DR and HLA-A+B+DR matching showed a little difference between the groups with different mismatches number in the Aza and CsA groups. Conclusion: Matching for the HLA-A+B significantly improved kidney graft survival in the Aza group. Matching for the HLA-DR and B+DR significantly improved kidney graft survival in the CsA group. The best kidney graft survival was observed in the HLA -A+B+DR identical combination group treated with Aza (80Fp at 5years); while in 0 HLA-A+B mismatched recipients treated with CsA (95% at 5years).

Catholic Medical Center 에서의 신이식 22 년 - 생체 신이식 600 예의 결과 -

윤영석(Young Suk Yoon),김용수(Yong Soo Kim),방병기(Byung Kee Bang),윤재영(Jae Young Yoon),박용현(Yong Hyun Park),박철주(Chul Joo Park),고용복(Yong Bock Koh) 대한내과학회 1992 대한내과학회지 Vol.43 No.4

N/A Background: The results of twenty-two years of renal transplantation at the Catholic Medical Center have been reviewed to analyze data of transplants performed between March 1969 and March 1991, During these time our center has transplanted 578patients with 600allografts. We reviewed the factors which effect on the graft survival. Methods: The data have stratified to reflect differences in 1) immunosuppressants; 2) HLA matching; 3) donor sources; 4) graft number; 5) diabetics; 6) HBV status; 7) donor specific transfusion (DST); 8) number of pretransplant blood transfusion. Results: Overall actuarial 5-year patient and graft survivals were 77% and 66%, respectively. The actuarial 5-year graft survivals for the Aza-(n=141) and the CsA-(n=431) treated recipients were 51% and 76% respectively (p=0,00001), The actuarial 5-year graft survivals for the HLA-identical (n=4), haploidentical (n=85) and mismatched (n=26) groups were 75%, 54g and 3196 in the Aza group (p-0.0159); and HLA-identical (n=14) 77% haploidentical, (n=197) 77% 4mismatched groups (n=220) 81% in the CsA group (p= 0. 7432). The actuarial 5-year graft survivals according to related (n=294), non-related living donors (n=275) and cadavers (n =9) were 66%, 70% and 44%, respective- 1v (p=0.1182). The actuarial 5-year graft survivals for the first graft (n=578) and regraft (n=22) were 66% and 35% respectively (p=0.1751). The actuarial 5-year graft survivals for the diabetics (n=18) and non-diabetics (n=560) were 62% and 66%, respectively (p=0.5457). The actuarial 5-year graft survival for the HBV positive (n=47) and the negative (n =381) groups were 61% and 78%, respectively (p=0.1195). The actuarial 5-year graft survivals according to DST (n=123) and non-DST (n=314) in the CsA-treated recipients were 75% and 76%, respectively (p=0.6538); and the number of pretransplant blood transfusion, 0 (n=54), 1-4 (n=180) and over 5 (n=206) units groups were 77%, 71 and 73% respectively (p= 0.7929). Conclusion: The best graft survivals were obtained in recipients who received CsA for immunosuppression, and HLA-identical for the Aza group; but not in the HLA matching for the CsA group, donor sources, diabetics or not, HBV status, graft number, DST and number of pretransplant transfusion.

텍스트 핑거프린트를 이용한 전자 출판물 식별 시스템

윤영석(Young-Suk Yoon),박지현(Jee-Hyun Park),이상광(Sang-Kwang Lee),유원영(Won-Young Yoo),이정문(Jung-Mun Lee) 한국통신학회 2011 한국통신학회 학술대회논문집 Vol.2011 No.6

조감도 기반의 객체 검출 시스템

윤영석(Young-Suk Yoon),정성욱(Sung-Uk Jung) 대한전자공학회 2019 대한전자공학회 학술대회 Vol.2019 No.6

삼차원 메쉬 모델에서 색상 정보와 법선벡터 정보의 압축 방법

윤영석(Young-Suk Yoon),김성열(Sung-Yeol Kim),호요성(Yo-Sung Ho) 한국통신학회 2005 한국통신학회 학술대회논문집 Vol.2005 No.6

연결성 정보와 기하학 정보를 이용한 삼차원 메쉬 모델의 광학성 정보 압축 방법

윤영석(Young-Suk Yoon),호요성(Yo-Sung Ho) 대한전자공학회 2008 電子工學會論文誌-CI (Computer and Information) Vol.45 No.3

본 논문에서는 삼차원 메쉬 모델의 광학성 정보를 부호화하기 위한 새로운 방법을 제안한다. 색상 정보, 법선벡터 정보 및 텍스처 정보의 부호화 효율을 개선하기 위하여 제안한 방법들은 기하학 정보와 연결성 정보를 이용하여 광학성 정보를 예측 부호화한다. 먼저 연결성 정보를 이용하여 광학성 정보의 부호화 순서를 결정하고, 이를 통해 얻어진 인접한 꼭지점들의 기하학 정보를 이용하여 광학성 정보를 예측 부호화한다. 색상 정보는 기하 예측기를 사용하여 부호화하고, 법선벡터 정보는 거리 균등화기와 최적화 평면 발생기를 적용하여 부호화하며, 텍스처 정보는 삼차원 메쉬 모델 분석기, 텍스처 좌표 분석기, 텍스처영상 재배열기와 예측 부호화기를 이용하여 부호화한다. 색상 정보는 현재 꼭지점과 인접한 꼭지점 사이에 기하학 정보를 고려하여 인접한 꼭지점들의 색상 정보의 가중치 합으로 계산할 수 있다. 또한 법선벡터 정보는 현재 꼭지점의 법선벡터를 예측하기 위해서 이등변 삼각형의 특성을 이용한 거리 균등화 기법과 상호연관성이 높은 인접한 꼭지점의 특징을 이용한 최적화 평면을 개발했으며, 효율적으로 삼차원 좌표를 압축하기 위해서 구면 좌표계와 6-4분할 양자화 방법을 사용하였다. 마지막으로 텍스처 정보는 부호화 순서에 따라 텍스처 영상의 조각을 재배열하여 텍스처 좌표를 불연속성을 제거한다. 다양한 삼차원 메쉬 모델들에 대해 실험한 결과를 살펴보면 제안된 압축 방법이 이전의 방법보다 개선된 부호화 효율을 제공하였다. In this paper, we propose new coding techniques for photometry data of three-dimensional (3-D) mesh models. We make a good use of geometry and connectivity information to improve coding efficiency of color, normal vector, and texture data. First of all, we determine the coding order of photometry data exploiting connectivity information. Then, we exploit the obtained geometry information of neighboring vertices through the previous process to predict the photometry data. For color coding, the predicted color of the current vertex is computed by a weighted sum of colors for adjacent vertices considering geometrical characteristics between the current vertex and the adjacent vertices at the geometry predictor. For normal vector coding, the normal vector of the current vertex is equal to one of the optimal plane produced by the optimal plane generator with distance equalizer owing to the property of an isosceles triangle. For texture coding, our proposed method removes discontinuity in the texture coordinates and reallocates texture image segments according to the coding order. Simulation results show that the proposed compression schemes provide improved performance over previous works for various 3-D mesh models.

시간지연 시스템의 PID제어기 동조방법 비교

윤영석(Young-Suk Yoon),서병설(Byung-Suhl Suh) 대한전기학회 2005 대한전기학회 학술대회 논문집 Vol.2005 No.10

만성요독증에서 적혈구막 Na+ - K+ ATPase 활성도에 대한 혈액투석의 효과

윤영석(Young Suk Yoon),양철우(Chul Woo Yang),조현미(Hyun Mi Cho),이길환(Kil Whan Lee),손현식(Hyun Sik Son),전영수(Young Soo Chun),최규보(Kyu Bo Choi),방병기(Byung Kee Bang),조규철(Kyu Chul Cho) 대한내과학회 1986 대한내과학회지 Vol.31 No.1

N/A To study the effects of hemodialysis on erythrocyte membrane Na+-K+ ATPase activity, we measured cytochemical Na+-K+ ATPase activity of erythrocyte in 36 patients with chronic uremia. The results were summarized as follows: 1) The Na+-K+ ATPase activity in the predialytic subjects was lower than that of normal controls(P=0), however value in the post-dialytic subjects was greater than that of normal controls(P<0.05). Also the value of postdialytic subjects increased significantly than that of predialytic subjects(P<0.001). 2) When an erythrocyte membrane taken from normal human was incubated with supernatantes of boiled plasma from predialytic individuals, the Na+-K+ ATPase activity of erythrocyte membrane was significantly lower than that of normal control(P<0.01). However, not significant difference between normal control and postdialytic subjects was seen. 3) The percent inhibition of Na+-K+ ATPase in the predialytic individuals was significantly higher than that of postdialytic individuals; the median value of inhibition in the predialytic group was 52.4%(range; -15.5~77.5%) and that of postdialytic group was -15.5%(range; -130.9~38.4%) (P<0.001). Based on the above findings, it is suggested that the hemodialyiss may acutely affect the erythrocyte sodium pump, possibly through the modulation of a dialyzable ouabain-like factor triggered by the extracellular volume change and removal of uremic toxin.