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Sunitinib (SU11248)에 의한 수족 증후군 2예
정진섭 ( Jin Seob Jeong ),윤정현 ( Jeong Hyun Yun ),윤석중 ( Seok Jung Yoon ),김원재 ( Wun Jae Kim ),이지연 ( Ji Yeoun Lee ),윤태영 ( Tae Young Yoon ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.9
Sunitinib (SU11248) is a novel orally administered small molecule that inhibits multiple receptor tyrosine kinases so that can block tumor growth and angiogenesis. It was approved on 2006, for the treatment of advanced renal cell carcinoma and gastrointestinal stromal tumor. Various cutaneous adverse reactions induced by sunitinib have been reported, including hand-foot syndrome. We report two cases of hand-foot syndrome induced by sunitinib for treatment of advanced renal cell carcinoma. (Korean J Dermatol 2008;46(9):1236~1239)
이주호,윤석중,김광수,유경무 고신대학교 의학부 1998 高神大學校 醫學部 論文集 Vol.13 No.1-2
Amnesia is a pathologic impairment of memory. The causal sites for amnesia are the medial temporal lobe and its connection to the mammillary body, upper brainstem, and hippocampus. We report a 66-year-old man who presented global amnesia. His brain MRI showed hemorrhage in the posteromedial area of the left thalamus. Brain SPECT showed small irregular focal hypoperfusion in the anteromedial area adjacent to the left frontal base.