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Anti-LKM1 양성 자가면역 간염에서 병발한 전신홍반루프스 1예
최대한 ( Dae Han Choi ),김해경 ( Hae Kyung Kim ),박태일 ( Tae Il Park ),전병민 ( Byung Min John ),강성환 ( Sung Hwan Kang ),이윤석 ( Yoon Serk Lee ),김태현 ( Tae Hyun Kim ),이우주 ( Uh Joo Lee ),이태승 ( Tae Seung Lee ),윤귀옥 ( G 대한소화기학회 2008 대한소화기학회지 Vol.51 No.3
Overlap of autoimmune hepatitis and systemic lupus erythematosus (SLE) is a comparatively rare condition. Although both autoimmune hepatitis and SLE can share common autoimmune features such as polyarthralgia, hypergammaglobulinemia and positive ANA, it has been considered as two different entities. We report a case of anti- LKM1 positive autoimmune hepatitis who developed SLE two years later. The presence of interface hepatitis with lymphoplasma cell infiltrates and rosette formation points to the autoimmune hepatitis rather than SLE hepatitis. Autoimmune hepatitis is infrequently accompanied by SLE, therefore, it could be recommended to investigate for SLE in patients with autoimmune hepatitis. (Korean J Gastroenterol 2008;51:190-193)