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헬스케어 빅데이터 유통을 위한 블록체인기술 활성화 방안
유형원,이은솔,고우균,한호성,한현욱,Yu, Hyeong Won,Lee, Eunsol,Kho, Wookyun,Han, Ho-seong,Han, Hyun Wook 한국빅데이터학회 2018 한국빅데이터학회 학회지 Vol.3 No.1
미래 의학의 핵심은 개인을 중심으로 한 정밀의료(Precision Medicine)의 실현이다. 이것이 가능하기 위해서는 헬스케어 데이터를 언제 어디서나 열람, 관리 및 유통 할 수 있는 개방형 생태계를 갖추어야 한다. 하지만, 헬스케어 데이터는 민감한 개인정보를 다루기 때문에 상당한 수준의 신뢰성과 보안성이 동시에 요구된다. 이를 해결하기 위한 방안으로 최근 의료계에서도 블록체인 기술에 주목하고 있다. 블록체인 기술은 거래정보를 중앙 서버에 저장 및 관리하는 기존의 정보통신 인프라와는 달리 유통되는 데이터를 네트워크에 참여하는 모든 사용자가 분산 및 관리하는 방식의 분산 운영망 이다. 본 연구에서는 블록체인 기술을 이용해 헬스케어 데이터 유통 실증에 필요한 기술적 및 법리적 제반 사항, 코렌(KOREN SDI)망 기반 헬스케어 빅데이터 유통 실증 연구의 소개 및 헬스케어 분야에서 블록체인 기술을 활성화하기 위한 정책적 전략에 대해 논의한다. At the core of future medicine is the realization of Precision Medicine centered on individuals. For this, we need to have an open ecosystem that can view, manage and distribute healthcare data anytime, anywhere. However, since healthcare data deals with sensitive personal information, a significant level of reliability and security are required at the same time. In order to solve this problem, the healthcare industry is paying attention to the blockchain technology. Unlike the existing information communication infrastructure, which stores and manages transaction information in a central server, the block chain technology is a distributed operating network in which a data is distributed and managed by all users participating in the network. In this study, we not only discuss the technical and legal aspects necessary for demonstration of healthcare data distribution using blockchain technology but also introduce KOREN SDI Network-based Healthcare Big Data Distribution Demonstration Study. In addition, we discuss policy strategies for activating blockchain technology in healthcare.
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점탄성층이 부분적으로 삽입된 샌드위치보의 횡진동 감쇠특성
박진택,유형원,장석원,최낙삼,Park, Jin-Taek,Yu, Hyeong-Won,Jang, Seok-Won,Choe, Nak-Sam 대한기계학회 2002 大韓機械學會論文集A Vol.26 No.2
The flexural vibration characteristics of a sandwich beam system with a partially inserted viscoelastic layer have been quantitatively studied using a finite element analysis in combination with a sine-sweep test. Antisymmetric mode shapes of the flexural vibration were visualized by the holographic interferometry and agreed with those calculated by the finite element simulation. Effects of the beam thickness as well as the length and thickness of partial viscoelastic layers on the system loss factor(η$\_$s/) and resonant frequency($\omega$$\_$r/) were significantly large fur the symmetric and antisymmetric modes of the beam system.
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김영민(Young Min Kim),김수진(Su jin Kim),이진욱(Jin Wook Yi),성찬용(Chan Yong Seong),김종규(Jong Kyu Kim),유형원(Hyeong Won Yu),채영준(Young Jun Chai),최준영(June Young Choi),이규언(Kyu Eun Lee) 대한갑상선-내분비외과학회 2016 The Koreran journal of Endocrine Surgery Vol.16 No.4
Purpose: Postoperative adhesion after thyroidectomy results in neck discomfort and swallowing difficulty. However, risk factors for adhesive symptom after thyroidectomy have not been well studied. This study evaluated symptoms related to postoperative adhesion after thyroidectomy. Methods: The Glasgow-Edinburgh Throat Scale (GETS) questionnaire was used to evaluate postoperative adhesion. Patients who completed the GETS questionnaire either pre- or post- operatively were enrolled. Patient clinical and pathological details including age, gender, body weight, body mass index (BMI), tumor size, thyroid volume, extent of thyroidectomy, postoperative months, and neck thickness on ultrasonography and computed tomography (CT) were abstracted. Results: Twenty-eight preoperative (22 females, six males) and 101 postoperative (83 females, 18 males) patients were enrolled. The mean age of the pre-operative enrollees was 52.1±11.7, and of post-operative enrollees 51.8±12.4 years. Patients who were within one month post-surgery had higher GETS scores than preoperative patients (27.4±20.1 vs. 6.5±11.1, P<0.001). Two months after surgery, GETS scores of postoperative patients did not differ significantly from the scores of the preoperative patients. There were no significant associations between clinical and pathologic features (age, tumor size, BMI, neck thickness on ultrasonography and CT) and GETS scores. Conclusion: Postoperative adhesive symptoms were most severe at one month after surgery, while questionnaire scores two months after surgery were comparable with preoperative patients. Further studies will be required for better understanding of the natural course of postoperative adhesion after thyroidectomy.
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원격전이가 동반된 미세 침윤형 여포암 환자의 임상병리학적 양상
주영욱(Young Wook Ju),김수진(Su jin Kim),채영준(Young Jun Chai),이진욱(Jin Wook Yi),성찬용(Chan Yong Seong),김종규(Jong Kyu Kim),유형원(Hyeong Won Yu),최준영(June Young Choi),이규언(Kyu Eun Lee) 대한갑상선-내분비외과학회 2016 The Koreran journal of Endocrine Surgery Vol.16 No.4
Purpose: Although minimally invasive follicular thyroid carcinoma (MIFTC) is considered a thyroid tumor with low malignant potential, some MIFTC can spread, metastasize, and eventually lead to death. This study investigates the risk factors for distant metastasis in MIFTC patients. Methods: Between 1981 and 2014, the records of 365 consecutive patients who underwent thyroidectomy for MIFTC at Seoul National University Hospital were reviewed. Univariate and multivariate analyses were performed to identify risk factors associated with distant metastasis. Results: Of 351 patients, 10 (2.9%) presented with distant metastasis. Of these, two (0.6%) were found at the time of thyroidectomy, while eight (2.3%) were detected at later exams, over a median of 7.3 years (range, 0.2∼30.8). In univariate analysis, lymph node metastasis (P<0.001) was significantly associated with distant metastasis. In multivariate analysis, lymph node metastasis (P<0.001) and locoregional recurrence (P=0.008) were significantly associated with distant metastasis. Conclusion: Distant metastasis in MIFTC patients were associated with high-risk clinicopathologic features and more aggressive clinical courses. Further study will be needed to ascertain these results with long-term surveillance.
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