철도 차량 유리창에 발열 유리 시스템 사용시 객실 온도 변화에 대한 연구

안종곤(Ahn jong-kon),유석희(Yoo suk-hee),강범수(Kang beom-su),권진(Kwon-jin),임원석(IM won-suk),강주희(Kang ju-hee) 한국철도학회 2009 한국철도학회 학술발표대회논문집 Vol.2009 No.5월

건축기술의 발달로 유리가 벽의 구조로 일반화되어 건축되고 있으며. 기존 벽의 역할인 수직 하중을 지탱하는 역할이 없어지게 되었다. 기능과 아름다운 면을 강조하게 되어 벽이 커튼의 역할만 하게 되어 객차 실내 유리창에 접근시 차가운 느낌으로 불쾌감을 유발 한다. 그리고 유리창 아래에 바닥 난방을 했음에도 유리창에 외풍 발생으로 결로 현상이 발생하며 즉 유리창 주변에 물방울이 발생(곰팡이 발생 원인)하여 겨울철 난방 에너지와 여름철 외부 온열이 유리를 통해 이동 하게 된다. 그러므로 에너지효율감소에 절대적으로 영향을 준다. 객차에 발열 유리시스템을 적용하면 유리창 표면에는 냉기의 확산이 발생 하지 않으며. 객차의 실내 냉 난방시 에너지 절감 효과가 있다. To the development of construction techniques and construction of glass-walled structure is generalized. Existing wall to support the role of the vertical load was lose. Features and the beautiful side of the curtain wall job was to be highlighted. Carriage access to the interior of the windows will cause pain in the neck with a cold feeling. And in the windows, drafty windows, under floor heating occurs despite the condensation phenomenon occurs. droplets that occurs around the window (the cause of the mold) in summer and winter, the heat energy and move through the glass is warmer outside. Therefore, to reduce energy efficiency affects absolutely. When you apply heat to the carriage window, the surface of the glass system, the spread of the cold air does not occur. Therefore, energy savings cars and heating of the interior is cold.

외상 수술후 발생한 급성 초점성 신피질괴사 1 예

임종찬(Jong Chan Lim),유호준(Ho Jun Yoo),심상준(Shang Jun Shim),유석희(Suk Hee Yu),이현순(Hyun Soon Lee) 대한내과학회 1989 대한내과학회지 Vol.37 No.5

N/A Acute cortical necrosis is a rare but catastrophic disease due to complete or partial destruction of all elements of the renal cortex. The clinical picture of the disease is characterized by acute renal failure, often with a fatal outcome. We report a case of acute cortical necrosis following an operation of the abdominal stab wound. A 22-year-old man was admitted to our hospital because of an abdominal stab wound. A segmental resection of the sigmoid colon and midileum and end to end anastomosis were performed. Oliguria developed on the third hospital day and was treated with hemodialysis therapy on the third hospital day and was treated with hemodialysis therapy on the 5th hospital day. The anuria persisted for 20 days and the total period of oliguria was 28 days. On the 73rd hospital day, a kidney needle biopsy was done and microscopic examination of the specimen showed cortical necrosis of the patchy form with fibrosis and calcification, The patient had received a total of 13 hemodialysis therapy sessions and was complicated by an episode of septicemia which originated from the indwelling femoral catheter. The recovery of renal function was incomplete but was sufficient to persist without hemodialysis therapy.

Epstein-Barr Virus 감염에 동반된 용혈 요독 증후군

김도형 ( Do Hyoung Kim ),유수정 ( Soo Jeong Yoo ),이정안 ( Jung Ahn Lee ),박지현 ( Jee Hyoun Park ),민철홍 ( Cheul Hong Min ),오동진 ( Dong Jin Oh ),유석희 ( Suk Hee Yu ),강응택 ( Eung Tack Kang ) 대한신장학회 2005 Kidney Research and Clinical Practice Vol.24 No.6

당뇨병성 신병변의 임상 및 병리학적 관찰

김응진 ( Eung Jin Kim ),민헌기 ( Hun Ki Min ),최동섭 ( Dong Seop Choi ),유석희 ( Suk Hee Yoo ) 대한내과학회 1980 대한내과학회지 Vol.23 No.2

Cushing 증후군의 임상적 고찰

민헌기 ( Hun Ki Min ),최동섭 ( Dong Seop Choi ),유석희 ( Suk Hee Yoo ),황승덕 ( Seung Dug Hwang ),윤경우 ( Kyung Woo Yoon ),유형준 ( Hyung Joon Yoo ) 대한내과학회 1981 대한내과학회지 Vol.24 No.4

혈액투석 시 칼슘역동학이 심혈관계에 미치는 영향

김차현(Cha Hyun Kim),오동진(Dong Jin Oh),유수정(Soo Jeong Yoo),이태우(Tae Woo Lee),최재영(Jae Young Choi),이광제(Kwang Je Lee),김상욱(Sang Wook Kim),유석희(Suk Hee Yu),강응택(Eung Taek Kang) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.5

목 적 : 혈관의 완충 기능을 반영하는 arterial compliance (AC)는 혈관 경직에 의해서 감소되고, 수축기 혈압 증가와 확장기 혈압 감소를 일으켜 맥압의 증가를 초래한다. 혈액 투석 환자에서 혈청 칼슘 농도는 투석액 내 칼슘 농도에 비례하고 이의 증가는 혈관 수축을 일으키며 혈관 경직과 연관성이 있다 이에 본 연구자는 저 칼슘 투석액 및 고칼슘 투석액 치료 후 arterial compliance, 수축기 및 확장기 혈압, 맥압과 더불어 생화학적 지표의 변화를 알아보고자 하였다. 방 법 : 8명의 혈액 투석 환자를 대상으로 (평균연령 45.5세, 남녀비 1 : 1) 하였고 평균 투석 기간은 3.5년이었다. AC, sroke volume (SV), 수축기 및 확장기 혈압, Ionized Ca, T-CO_2 둥을 저칼슘 투석액 (Gambro, Bicart 761 solution^ )과 고칼슘 투석액으로 각각 10회 치료 후 수치를 비교하였다. 결 과 : AC의 기저 평균치는 0.143±0.076 ㎟/kpa, 저칼숨 투석액 (1.25 m㏖/L) 치료 후 0.166±0.097 ㎟/kPa, 고칼숨 투석액 (1.75 m㏖/L) 치료 후는 0.142±0.082 ㎟/kPa로 8명 증 6명에서 감소양상을 보였으나 통계적 유의성은 없었다 (p>0.05). 수축기 혈압, 확장기 혈압, 평균 동맥압, 맥압의 기저 평균치는 각각 157.75±15.97, 94.259.49, 114.12±10.56, 63.50±10.87 ㎜Hg이었고 저칼슘 투석액 (1.25 m㏖/L) 치료 후는 각자 135.25±13.00, 78.75±11.24, 98.37±15.14, 55.50±5.95 ㎜Hg, 고갈슘 투석액 (1.75 m㏖/L) 치료 후는 각각 160.50±15.36, 94.05±10.34, 115.75±9.64, 62.00±15.71 ㎜Hg로 통계적으로 의미있는 변화를 관찰할 수 있었다 (p<0.05). 혈중유리 칼슘의 기저 평균치는 4.66±0.40 ㎎/dL, 저칼슘 투석액 (1.25 m㏖/L) 치료 후 4.45±0.28 ㎎/dL, 고칼슘 투석액 (1.75 m㏖/L) 치료 후는 4.65±0.43 ㎎/dL이었으나 다른 생화학적 지표들은 변화가 없었다. 결 론 : 저칼슘 투석액 사용시 arterial compliance는 62%의 환자에서 증가되었으나 통계적 유의성은 없었고 수축기 및 이완기 혈압, 평균 동맥압, 맥압의 평균치는 통계적으로 유의하게 감소되는 것으로 보아 혈액투석 환자에서 저칼슘 투석액은 심혈관계 질환 예방에 도움이 될 것으로 생각된다. Objective : Arterial compliance (AC) reflects the buffering function of the vessel. Low AC caused by arterial stiffness increases pulse pressure amplitude. Therefore, Low AC must be correlated with high cardiovascular mobidity and mortality in HD patients. Dialysate calcium concentration is potentially a main determinant of serum ionized calcium level and the vasoconstriction is associated with high calcium concentration. Therefore, We conducted a study for evaluation of the interdialytic effects of treatment with a low dialysate calcium (LdCa) concentration and high dialysate calcium (HdCa) concentration on the changes of AC, BP, biochemical parameters. Methods : Eight HD patient (mean age 45.5, sex ratio 1 : 1) were studied. The mean HD period was 3 years. Arterial Compliance, stroke Volume, SBP, DBP, PP, MAP, Ionized Ca, T-CO_2, P and Ca×P product were compared after treatment with a LdCa and HdCa concentration for each 10 sessions. Results : AC were 0.143±0.076 ㎟/kPa in baseline, 0.166±0.097 ㎟/kPa in LdCa (1.25 m㏖/L) dialysate, 0.142±0.082 ㎟/kPa in HdCa (1.75 m㏖/L) dialysate. SBP, DBP, MAP and PP were 157.75 15.97, 94.25±9.48, 114.12 10.56, 63.50±10.87 ㎜Hg in baseline and 135.25±13,00, 78.75±11.24, 98.37 15.14, 56.50±5.95 ㎜Hg in LdCa dialysate and 160.501±15,36, 94.05 10.34, 115.75±9.64, 62.00±15.71 ㎜Hg in HdCa dialysate. Ionized Ca were 4.66±0.40 ㎎/dL in baseline, 4.45±0.28 ㎎/dL in LdCa dialysate and 4.65±0.43 ㎎/dL in HdCa dialysate. However, there were no changes of other biochemical parameters. Conclusion : Treatment with LdCa dialysis, by minimizing the risk for LdCa-induced hypocalcemia, may have a beneficial role in the prevention of the ongoing reduction of arterial compliance in HD patients and thus improve cardiovascular prognosis.

한탄바이러스에 감염된 사람제대정맥 내피세포에서 ICAM-1 및 VCAM-1 의 발현

설무종(Moo Jong Seol),이태우(Tae Woo Lee),김차현(Cha Hyun Kim),최재영(Jae Young Choi),유수정(Soo Jeong Yoo),오동진(Dong Jin Oh),유석희(Suk Hee Yu),강응택(Eung Taek Kang) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.5

배 경 : 신증후출혈열은 한탄바이러스에 의한 급성 발열성 질환으로 병인에 여러 가지 염증매개불질들이 알려져 있다. 방 법 : 본 연구에서는 한탄바이러스에 감염된 사람 제대정맥 내피세포에서 ICAM-1 및 VCAM-1의 발현 정도를 효소면역측정법을 이용하여 정량 측정하였다. 결 과 : 한탄항원에 대한 반응은 감염 후 48시간부터 중가하기 시작하였으며. ICAM-1의 발현은 감염 후 3시간이 지나면서 급격히 중가하였다. VCAM-1의 발현은 ICAM-1의 발현보다 약간 지연되었으며 감염 후 4시간이 지나면서 급격히 증가하였다. 이 같은 ICAM-1, VCAM-1 발현 증가는 희석되지 않은 바이러스를 감염 시켰을 때 더 현저하였으며 희석된 바이러스를 참염시켰을 때에는 반응이 미약하였다. 결 론 : 한탄바이러스가 사람제대정맥 내피세포에 감염되면 ICAM-1 및 VCAM-1의 발현이 증가됨을 관찰하였고 이를 효소면역측정법을 이용하여 정량격으로 비교하였다. Purpose: Hemorrhagic fever with renal syndrome (HFRS) is an acute febrile disease caused by Hantaan virus. It is believed that various kinds of inflammatory mediators and cytokines might be involved in its pathogenesis. Methods : We studied the expression of adhesion molecules, including ICAM-1 and VCAM-1 on Hantaan virus-infected human umbilical vein endothelial cells (HUVECs) with ELISA. Results : Hantaan antigen increased gradually 48 hours after virus infection, ICAM-1 increased rapidly 3 hours after virus infection and VCAM-1 increased rapidly 4 hours after infection, a little later than ICAM-1. The patterns of the change of reaction were similar between the different concentrations of virus solution that had been adsorbed on HUVECs, but the expression of ICAM--1 or VCAM-1 was greater when HUVECs were infected with stock virus rather than when infected with tenfold diluted virus. Conclusion : We report the quantification using ELISA of ICAM-1 and VCAM-1 expression of HUVECs that have been infected by Hantaan virus. Increase of their expression would play an important role in the pathogenesis of HFRS.

산-염기 평형 장애 진단 전문가 시스템의 설계 및 구현

김기태,유석희,황수철 중앙대학교 기술과학연구소 1989 기술과학연구소 논문집 Vol.19 No.-

In this study, we designed and implemented a diagnostic system model to process the diagnosing problem of acid-base balance disorder by means of OPS5 and LISP which are a tool and a language, respectively for developing Al systems. The implemented knowledge base system consists of three kind of the knowldege : one analytic knowledge of blood test, two diagnostic knowledges obtained by etiologies and symptoms. The knowledge representation and the inference mechanism for diagnosis were implemented by OPS5, and all input / output was processed by a menu-driven method in support of the window functions of LISP.

만성 신부전의 빈혈에 대한 유전자 재조합 인 에리쓰로포이에틴(에포론) 의 유효성 및 안전성 평가를 위한 연구 : 제 Ⅲ 상 임상시험

이호영,강경원,강종명,노현진,신석균,유석희 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.6

To examine the effectiveness and safety of erythropoietin on the anemia of end-stage chronic renal failure, we administered recombinant human erythropoietin(rHuEPO), Eporon, to 66 patients with anemia and chronic renal failure who were undergoing hemodialysis or peritoneal dialysis. All received Eporon intravenously, two or three times per week at 150unit/kg, and then the dose of Eporon was adjusted to 75-300unit/kg/week according to the hemoglobin response. The results of this study judged 19(39.6%) of 48 patients as being in a $quot;markedly improved$quot; condition while 23(47.9%) of 48 patients were judged as being in an $quot;improved$quot; condition. At results, the response rate of this study was 87.5%(42/48 patients). This was the same as the target response rate, 90%(p=0.564). Serious adverse events occured in 6 cases during the study, but all proved to be unrelated to Eporon^ⓡ. These events included itching 1(1.5%), urticaria 1(1.5%) and headache 1(1.5%). No patients discontinued to participate in the study except one patient who withdrew from the study voluntarily. The symptoms of all adverse events eventually decreased and disappeared during the clinical study. No factors in the clinical laboratory tests changed significantly (p$lt;0.05) except for the decrease of TSR and ferritin, a consequence of using iron hemoglobin synthesis caused by Eporon administration. The significant increase in blood pressure, which could not be proved to be related to Eporon^ⓡ, disappeared during the study. Anti-Epo antibody was not detected in any samples. These results demonstrate that Eporon is effective in many patients with the anemia of end-stage chronic renal failure.