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무기폐(無氣肺)가 폐표면활성도(肺表面活性度)에 미치는 영향에 관(關)한 실험적(實驗的) 연구(硏究)
우종수,조광현,김종원,손말현,신근수,김진식,Woo, Jong Soo,Cho, Kwang Hyun,Kim, Jong Won,Sohn, Mal Hyun,Sihn, Kun Soo,Kim, Jin Shik 대한흉부심장혈관외과학회 1976 Journal of Chest Surgery (J Chest Surg) Vol.9 No.2
The effects of atelectasis on surface activity of lung extracts were examined in rabbits. Experimental atelectasis was produced in rabbits by artificial pneumothorax and surface tension properties were measured on saline extracts of lung 24 hrs, 48 hrs, one week and four weeks after the induction of pneumothorax. The results were as follows; 1) The minimum surface tension of excised lung extracts 24 hrs after pneumothorax was significantly increased to 28.3 0.41 dynes/cm, and the stability index was significantly decreased to 0.30 from normal value of 0. 87. 2) In the group which was re-expanded 24 hours, later from pneumothorax the surface activity was returned to almost normal range 24 hrs after reexpansion of collapsed lung, 3) When the atelectasis was continued by mechanical means, the extracts of atelectatic lung showed progressive decrease in surface activity, but it was found that surface activity returned to normal level after four weeks even the presence of atelectasis. 4) These observations suggest to us that atelectasis per se does not cause an increase in surface tension of lung extracts, and even in prolonged atelectasis the re-expansion of collapsed lung may be possible when the mechanical cause of atelectasis was excluded.
연구논문(硏究論文)(재록(再錄)) : 생명과학 ; 생체이용율이 증가된 cyclosporine A 함유 히알우로닉 미립구의 개발
우종수 ( Jong Soo Woo ),박명관 ( Ming Guan Piao ),이동훈 ( Dong Xun Le ),유동성 ( Dong Sung Ryu ),최준영 ( Jun Young Choi ),김정애 ( Jung Ae Kim ),김정훈 ( Jeong Hoon Kim ),진성규 ( Sung Giu Jin ),김대덕 ( Dae Duk Kim ),류원석 ( W 영남대학교 약품개발연구소 2007 영남대학교 약품개발연구소 연구업적집 Vol.17 No.-
유소아(幼小兒) 막흉(膜胸) 100례(例) 대(對)한 임상적(臨床的) 고찰(考察)
김종원,우종수,정황규,Kim, Chong Won,Woo, Jong Soo,Chung, Hwang Kiw 대한흉부심장혈관외과학회 1976 Journal of Chest Surgery (J Chest Surg) Vol.9 No.2
The author made clinical study of 100 cases of empyema in infancy and childhood that were treated at the Department of Chest Surgery, Busan University Hospital and Busan Children's Charity Hospital, from Jan 1962 to Nov. 1975. 1. In infancy and childhood, 62 cases out of my 100 cases of empyema were caused by .staphylococci and most of recent reports showed a gradual increase in number of staphylococcal empyema. 2. Most frequent lesion predisposing to empyema in infancy and childhood was pneumonia (72%), being remarkable in staphylococcal empyema (85.5%) to that of others. 3. Antibiotics sensitivity test for staphylococci revealed that the erythromycin was most susceptible (85. 5%). 4. The mortality rate was 6% in over all and the author believes that from the point of view of surgical treatment, failure of early continuous drainage on account of multiple thoracentesis for the early stage of empyema, and also early open thoracotomy procedure such as decortication were all the contributing factors to higher mortality in the empyema of infancy and childhood. 5. It may be concluded that the treatment of choice for empyema in infancy and childhood were early and prolonged continuous drainage of pus by closed thoracotomy with caution and administration of more susceptible antibiotics with nutritional support.