전신성 홍반성 루푸스 환자에서의 악성임파종 치험례

우순섭,강학수,이영수,심광섭,유광희,Woo, Soon-Seop,Kang, Hag-Soo,Lee, Young-Soo,Shim, Kwang-Sup,Yoo, Kwang-Hee 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.2

Systemic lupus erythematosus is a severe cutaneous-systemic disorder of unknown etiology, It is represented with erythematous patches on the face in a so-called butterfly distribution, and characteristically classified as an autoimmune disease with antinuclear antibodies. The autoimmune diseases such as systemic lupus erythematosus, $Sj{\ddot{o}}gren$ syndrome, rheumatoid arthritis have been associated with lymphoid malignancy - leukemia, malignant lymphoma - which could involve various organs(spleen, liver, brain, mediastinal lymph node, supraclavicular lymph node, inguinal lymph node, cervical lymph node etc.). Many authors have studied about the association of systemic lupus erythematosus and malignant lymphoma, but exact etiology is still unknown. A common viral etioloty for systemic lupus erythematosus has been suggested since virus-like particles have been found in the glomerular endothelium of patients with systemic lupus erythematosus. These oncogenic viruses may be responsible for the higher frequency of malignant lymphoma in patients with systemic lupus erythematosus. In the other theory, the causes of malignant lymphoma are the defect of immune system due to systemic lupus erythematosus and the long-term use of therapeutics for treatment of systemic lupus erythematosus. When the cellular immune system(delayed hypersensitivity) is impaired by immunosuppressive drugs, it is likely that the body is no longer able to recognize and reject malignant cells as they arise; they continue to grow and divide unhindered. The impairment of the cellular immune system may allow growth of oncogenic virus or the survival of neoplatic tissues. 47-year old female patient treated systemic lupus erythematosus with steroid and immunosuppressive drugs for 5 years visited to our hospital due to elevated mass on left upper anterior maxilla area. By performing biopsy, we diagnosed this lesion as malignant lymphoma and referred to oncologist for chemotherapy. So we report a case of malignant lymphoma due to systemic lupus erythematosus with review of literatures.

하악지시상분할절단술에 의한 하악전돌증 수술후 상순의 변화에 관한 연구

우순섭,위현철,이영수,심광섭,Woo, Soon-Seop,We, Hyun-Chul,Lee, Young-Soo,Shim, Kwang-Sup 대한악안면성형재건외과학회 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.1

Recently, sagittal split ramus oseotomy and intraoral vertical ramus osteotomy have been commonly performed for the correction of mandibular prognathism, occurred to abundant oriental people. Many authors have studied the soft tissue change after orthognathic surgery, especially between mandibular hard tissues and soft tissue of lower lip, but the study of upper lip change is comparatively little. Therefore, we studied the 12 patients, operated only sagittal split ramus osteotomy without genioplasty or maxillary osteotomy in department of oral and maxillofacial surgery, Hanyang university hospital from 1996. 1. 1. to 1998. 7. 20. Preoperative and postoperative cephalometric view was measured to know the change of upper lip position and shape after mandibular setback. The result were obtained as follows. 1. The ratio of upper lip change amount to lower incisor horizontal movement was 15.1%. 2. The ratio of lower facial profile between Sn-Stm and Stm-Mes was changed from 1 : 2.352 to 1 : 2.069 after operation. 3. Post-operative upper lip was flattened 72.4% compared with pre-operative one. 4. The vermilion zone of the upper lip increased 56 % horizontally, 5.8% vertically after operation. 5. The vermilion zone ratio of the lower lip to the upper lip was changed from 1 : 1.253 to 1 : 1.348. 6. The distance between esthetic line and Ls was changed from -3.958mm to -1.15mm.

진성 골격성 Ⅲ급 부정교합에서 두개저, 상악, 하악의 위치 및 크기에 관한 연구

우순섭(Soon-Seop Woo),최용수(Yong-Soo Choi),박원희(Won-Hee Park),유임학(Im-Hag Yoo),이영수(Young-Soo Lee),심광섭(Kwang-Sup Shim) 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.1

The facial patterns were expressed by the interrelation of variable factors such as heredity, function and environment. Such variable factors have an effect on the growth and development of maxillofacial bones. The malocclusions with skeletal discrepancies are caused by abnormal forms, sizes and positions of cranial base, maxilla and mandible. For the proper diagnosis and treatment planning, the analysis of such structures is necessary. Lateral cephalograms of 54 adults with class Ⅲ malocclusion patients (test group) and 61 adults with normal occlusion (control group) were analyzed. Anteroposterior relations and sizes of cranial base, maxilla, mandible were estimated to compare with those of normal ones. In test group, the anterior cranial base length was within normal range, but posterior cranial base, maxilla and mandibular body were longer than those in control group, significantly. Based on the cranial base, the location of maxilla in test group was normal, but the location of mandible was more anterior than that in control. Based on the maxilla, the location of mandible was more anterior in test group than that in control. Both mandibular body and ramus anteroposterior lengths in test group were larger than those in control. Both mandibular plane angle and upper gonial angle were within normal range, but lower gonial angle was significantly high in test group.

악교정 수술을 위한 한국인 하악지의 해부학적 위치에 관한 연구

우순섭(Soon-Seop Woo),조정연(Jung-Yeon Cho),박원희(Won-Hee Park),유임학(Im-Hag Yoo),이영수(Young-Soo Lee),심광섭(Kwang-Sup Shim) 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.2

Anatomical shape of the mandibular ramus, which includes the area from the rear of the mandibular second molar to the mandibular posterior border and from the mandibular sigmoid notch to the inferior mandibular border, must be carefully considered to perform orthognathic surgery. The locations of the lingula and mandibular foramen in medial side of mandibular ramus are one of the most important factors to decide the location of the horizontal medial osteotomy in sagittal split ramus osteotomy and to select the line of vertical osteotomy in intraoral vertical ramus osteotomy. Sixty-five different Korean human dry mandibles were surveyed. All mandible have permanent dentition including complete eruption of the mandibular second molar. The locations of the lingula and mandibular foramen in medial side of the ramus were identified and following results were obtained. Anterior ramal horizontal distance from lingula was 16.13±3.53mm(range:8.6-24.3mm), anterior ramal horizontal distance from mandibular foramen was 23.91±4.79mm(range: 14.1-39.7mm), horizontal width of mandibular foramen was 2.79±0.95mm(range: 1.5-6.1mm), height of lingula was 10.51±3.84mm(range: 3.1-22.4mm), vertical distance from sigmoid notch to lingula was 19.82±5.11mm(range: 9.1-35.3mm). From this study, the result could be used to select the location of osteotomy lines and to decide amount of periosteal elevation to avoid injury of neurovascular bundle, and to accomplish the appropriate split in Korean patients in mandibular orthognathic surgery.

교정치료시 전치부 후방견인에 이용하는 SAS의 효율성

우순섭(Soon-Seop Woo),정순태(Soon-Tai Jeong),허영성(Young-Sung Huh),황경균(Kyung-Gyun Hwang),유임학(Im-Hag Yoo),심광섭(Kwang-Sup Shim) 대한구강악안면외과학회 2003 대한구강악안면외과학회지 Vol.29 No.4

The retraction of anterior teeth could be performed more easier by inducing of skeletal anchorage system rather than by conventional method on orthodontic treatment. But, we wonder how effective the system draws well without anchorage loss and draws anterior teeth aside posteriorly, and if the system can reduce the time, in comparison with the anchorage of posterior teeth. For that reason we have studied on the subject of patients, who were required the maximum anchorage on orthodontic treatment and the cases without crowding. The subjects of the experimental group are 35 areas of 20 people who were inserted miniscrews after Mx or Mn 1st premolar extracted. Also, the subjects of the control group are 81 areas of 45 people who were not inserted miniscrews. Compared the anchorage loss of experimental group with control one, we could get the result that the anchorage loss of experimental group is 1.034±0.891mm and control group is 2.790±1.882mm(P<0.01). Compared the space closing time of experimental group with control one, we could get the result that the space closing time of experimental group is 369.40±110.81days and control group is 406.56±231.63days. But the result of comparing space closing time has no significance in statistics. We recognized that the experimental group is more faster than the control group in the canine retraction velocity from the result ; the speed of a experimental group has as much as 0.60±0.23mm/30days while the speed of a control group has 0.44±0.35mm/30days(P<0.05). So, we could convince that orthodontic miniscrew is used effectively in the cases required the maximum anchorage.

한국인의 안면골 골절에 관한 통계적 연구

우순섭(Soon Seop Woo),이영수(Young Soo Lee),심광섭(Kwang Sup Shim) 대한구강악안면외과학회 1997 대한구강악안면외과학회지 Vol.23 No.3

For the establishment of the basis of treatment and study in the patients of facial bone fracture, we performed a clinico-statistical study about 28 papers and 9564 cases reported as facial bone fractures in the Journal of Korean association of oral and maxillofacial surgeons, the Journal of the Korean academy of maxillofacial plastic and reconstructive surgery, and related Journals. The results were as follows: 1. The ratio of men to wemen was 4.50:1. 2. The age frequency was highest in the third decade(37.6%), and fourth(21 5%), second(l5.5%), fifth(10 3%) decade in orders. 3. The most common location of facial bone fractures was the mandible(62.7%), and zygoma complex(22.6%), nasal bone(15.0%), and maxilla(13.0%) were next in order of frequency. 4. The major etiologic factors were traffic accident(37 9%), fisticuffs(26.4%), and falldown and slip down(23.4%). 5. The frequent fracture site of mandible is symphysis(39.3%), angle(24.4 %), and condyle(22.5%), The ratio of left to right was 1.31:1. Open reduction(69.1%) was the more frequently using method of treatment in mandibular fracture than colsed reduction(28.6%). 6. The sites of zygomatic fractures were zygoma complex(48.0%), zygomatic arch(35.7%), and combined(16 3%). The lett to right ratio was 1.37:1 7. The most frequent maxillary fracture was Le Fort I (31.4%), and Le Fort II (27.1%), unilateral(14.3%), Le Fort III (7.6%) were next in order of frequency.

구내고정원을 이용한 교정 치료중 miniscrew 탈락에 관한 연구

우순섭(Soon-Seop Woo),정순태(Soon-Tai Jeong),허영성(Young-Sung Huh),황경균(Kyung-Gyun Hwang),유임학(Im-Hag Yoo),심광섭(Kwang-Sup Shim) 대한구강악안면외과학회 2003 대한구강악안면외과학회지 Vol.29 No.2

At orthodontic treatment, we have made every effort to get rigid anchorage which is not stirred when teeth move. As a result, the miniscrew that is rigid anchorage was invented recently, and now it is used widely. Concerning the advantage of miniscrew, it is reduced dependence of extraoral anchorage and it shortens treatment time for rapid tooth movement. In contrast, the defect of miniscrew is falling off it resulted from increasing of the mobility. So the purpose of this research is to be of help to prognose clinical use of miniscrew, which is inserted for intraoral anchorage, by investigating and comparing the failure rate of miniscrew for loading time. This study researches the failure rate of miniscrew for teeth movement at the orthodontic treatment. The failure rate of miniscrew in mid course, after inserting 147 miniscrews in 51 patients, is 13%(20/147). It showed no statistically significant differences as compared man with woman, maxilla with mandible, double-head with uni-head miniscrew, and drilling and non-drilling before inserting the miniscrew. In comparison below twenties with over twenties and the times that we give load to miniscrew, it produced that the failure rate of miniscrew is 9.7% higher in the case of below the twenties than over the twenties. Also, the failure rate of loading immediately is 10.8% higher than loading after 7 days. According to using driver for the insertion of miniscrew, the failure rate of miniscrew is higher in the case of using machined driver than in the case of using hand driver when the level of significance is 95%. According to the research, we can suppose that the failure rate has no concern with using miniscrew on man or woman, maxilla or mandible, the shape of head, and drilling or non-drilling before insertion of miniscrew. Therefore, we can choose eclectic miniscrew as demands. In addition, we must notify the patient, below twenties, to be possibility of high failure rate. And It is strongly recommended to give load after 1􀅭2 weeks for healing of the insertion area.

가토 하악골 우각부의 골절단술후 골치유에 관한 실험적 연구

김종원(Jong Won Kim),우순섭(Soon Seop Woo) 대한구강악안면외과학회 1993 대한구강악안면외과학회지 Vol.19 No.2

The healing in osseous tissue different from soft tissue healing is the regeneration process which doesn t remain scar tissue. For primary bone healing, the ideal method is no gap and rigid fixation. But if the fragments could not fixed without gap, tight bone graft must be recommanded. However, actually in clinic, small gaps during fixation could be occurred, then many surgeons were willing to fix the fragments commonly without bone graft in small gaps because they did not want to make other wound. So, this experiment was performed to know the effect of various sized gap on the bone healing when the fragments were fixed with various sized gaps, and no bone grafts. After submandibular incision and angle exposure, the bony gaps of 0㎜, 1㎜, 3㎜, 5㎜, and 7㎜ were made in each 4 rabbits, and the fragments were fixed rigidly. After 20 weeks, the rabbits were sacrificed and their mandibles were extirpated. The observations and the measurements of the bony defects were performed, and the microscopic specimens were obtained. The results as follows 1. In group of no gap the wounds of bones were healed completely, and in group of 1㎜ the wound were also healed satisfactorily. In these groups, the bony continuities were kept, the new bones in the cut areas were irregular and had high cellularity. 2. In group of 3㎜ the sizes of remaining defects were similar as one of original defects. 3. In group of 5㎜, 7㎜ the defects were partly larger than original defects since bony resorption. From this experiment, author concluded that during reduction and fixation the fragments must be adhere closely without gap. If impossible, the gaps must be minimized.

양악전돌증 치료에서 피질골절단술의 효율성에 관한 연구

서영준,정성우,강학수,임재중,허영성,우순섭,심광섭,황경균,Seo, Young-Jun,Jung, Sung-Woo,Kang, Hag-Soo,Im, Jae-Jung,Huh, Young-Sung,Woo, Soon-Seop,Shim, Kwang-Sup,Hwang, Kyung-Gyun 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.4

In esthetic treatment of bimaxillary protrusion, it is important to move backward the anterior teeth segment. For the backward movement of the anterior teeth segment, orthodontic force and segmental osteotomy have been applied on the clinical treatment until recently. These methods caused long treatment time, anchorage loss, the possibility of root resorption and the complication followed by segmental osteotomy. Therefore, corticotomy has become a major concern lately. This research has been conducted to study the efficiency of corticotomy in the treatment of bimaxillary protrusion comparing the profile change, canine retraction velocity and space closing time. The research compared and analyzed space closing time, canine retraction velocity and profile change in two groups of patients. Both groups were formed out of patients over 18 years old who visited the department of dentistry in Hanyang University for treatments. The experimental group who was treated by corticotomy and Skeletal Anchorage System(SAS). The control group who received orthodontic treatment using SAS. The following results are produced after analyzing both groups. The significant statistic difference in space closing time has been observed in the experimental group as compared with the control group(p<0.05). In the experimental group, the significant statistic increase in canine retraction velocity was also observed(p<0.05). There was no significant difference in profile change between the control group and the experimental group(p<0.05). As a result, orthodontic treatment using corticotomy has a reasonable efficiency in space closing time as compared with the existing orthodontic treatment. Therefore, it is concluded that corticotomy with orthodontic treatment can be reasonably applied to dentofacial abnormality.

경구개의 소타액선에서 발생한 타액선관 암종

김종원(Jong Won Kim),김명진(Myung Jin Kim),우순섭(Soon Seop Woo) 대한구강악안면외과학회 1993 대한구강악안면외과학회지 Vol.19 No.4

In 1968, Kleinsasser et al described the 5 cases of salivary duct carcinoma as a specific diagnostic category of salivary gland adenocarcinoma. Salivary ductal carcinoma is uncommon salivary gland neoplasm which has a characteristic morphologic pattern, intraductal and infiltrating papillary carcinoma, comedonecrosis, and infiltrating ductal carcinoma with reactive fibrosis. This disease occurs predominantly in male, in sixth and seventh decade and in parotid gland. We first experienced a 64-year old man with salivary duct carcinoma of the minor salivary gland in hard palate. So in this paper, we describe the clincopathologic findings, treatment, and clinical course in the patient.