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이석정 ( Seok Jeong Lee ),리원연 ( Won Yeon Lee ),정순희 ( Soon Hee Jung ),권우철 ( Woo Cheol Kwon ),이선녕 ( Shun Nyung Lee ),이남석 ( Nam Seok Lee ),김상하 ( Sang Ha Kim ),신계철 ( Kye Chul Shin ),용석중 ( Seok Joong Yong ) 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.6
We report on a case of a patient with laryngo-tracheobronchial amyloidosis who complained of cough, sputum, and hoarseness. A chest X-ray showed consolidation in the right middle lobe. A chest CT scan showed diffuse, irregular narrowing of the tracheobronchial tree and atelectasis of the right middle lobe, with calcification of bronchial wall. Bronchoscopic findings were multinodular submucosal thickening of the right vocal cord, and yellowish multinodular submucosal thickening from the lower trachea through both main bronchi, as well as the lingular division of the left upper lobe, the right middle lobe, and the right lower lobe. The right middle lobe bronchus was nearly obstructed. The diagnosis of amyloidosis was made by multiple bronchoscopic biopsies on the right vocal cord and both bronchi. Pathologic findings were characteristic apple-green birefringence under polarized microscopy with Congo-red stain. The patient had no evidence of systemic amyloidosis. The patient is under conservative symptomatic treatment. (Tuberc Respir Dis 2008;65:532-536)
이달의 X-선 : 중심정맥카테터 삽입의 이상위치로 발생한 편측성 흉수 1례
김재석 ( Jae Seok Kim ),김상하 ( Sang Ha Kim ),이낙원 ( Nak Won Lee ),권우철 ( Woo Cheol Kwon ),최훈 ( Hun Choi ),변종원 ( Jong Won Beon ),홍태원 ( Tae Won Hong ),신계철 ( Kye Chul Shin ),용석중 ( Suk Joong Yong ) 대한결핵 및 호흡기학회 2006 Tuberculosis and Respiratory Diseases Vol.60 No.6
중심정맥카테터 삽입 후 생길 수 있는 드문 합병증 중에 하나인 흉수 발생은 카테터와 관련된 혈관벽의 손상을 흉수 발생의 기전으로 설명하고 있다. 저자들은 우측 쇄골하정맥으로 이어지는 이상혈관 내로 카테터가 위치한 후 혈관 파열로 인하여 발생한 흉수 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Central venous catheterization is used to provide a large amount of fluid, total parenteral nutrition and to administer antitumor agents with few complications reported. We report an uncommon case of pleural effusion that occurred after central venous catheterization. In many cases, the mechanism for the pleural effusion after central venous catheterization occurs through an injury to the superior vena cava by the continuous mechanical force of the catheter tip, the flow of large amount of fluid and an osmotic injury to the wall of the vein. This case is somewhat different in that the central catheter was placed in an aberrant vessel resulting in the pleural effusion. A post-placement chest roentgenogram and the correct approach of catheterization are important for preventing this complication. (Tuberc Respir Dis 2006; 60: 690-693)
이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),노진규 ( Jin Kyu Noh ),이민수 ( Min Su Lee ),이남석 ( Nam Seok Lee ),이부길 ( Bu Ghil Lee ),리원연 ( Won Yeon Lee ),용석중 ( Suk Joong Yong ),신계철 ( Kye Chul Shin ),김상하 ( Sa 대한천식알레르기학회 2008 천식 및 알레르기 Vol.28 No.4
Occupational allergic rhinitis caused by rabbit fur has been reported in Korea. However, occupational asthma due to rabbit fur has not yet reported in Korea. We report a suspected case of allergic asthma caused by rabbit fur on occupational exposure. A 35-year-old male developed dyspnea, chest discomfort related to rabbit fur. He has been worked for a spinning factory. He presented with a history of allergic rhinitis and asthma. Peripheral blood eosinophil count was 690/mm3. Bronchodilator response was positive, the results of skin prick test were positive for house dust mite, cockroach and rabbit fur. The level of specific IgE for rabbit fur was 8.39 KU/L. The methacholine challenge test was positive (PC20 1.96 mg/mL). These findings suggest that the rabbit fur could induce occupational asthma. We could not perform bronchoprovacation test with rabbit fur due to patient`s refusal. He is in a well controlled state with the use of a combination of inhaled corticosteroid and long acting β2 agonist after the avoidance of rabbit fur. (Korean J Asthma Allergy Clin Immunol 2008;28:309-312)
성인 비아토피 호흡기알레르기 환자에서 혈청 총 IgE와 신체질량지수의 관계
이지호 ( Ji Ho Lee ),리원연 ( Won Yeon Lee ),용석중 ( Suk Joong Yong ),신계철 ( Kye Chul Shin ),이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),김종환 ( Chong Whan Kim ),정세현 ( Sae Hyun Jung ),정예령 ( Ye Ryung Jung ),김상하 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.4
Background: Serum total IgE levels are increased in some obese patients with nonatopic respiratory allergy. It has not yet been fully determined a significant relationship between total IgE and body mass index (BMI) in nonatopic patients. We sought to examine the relationship between total IgE and BMI in patients with nonatopic respiratory allergy. Methods: We retrospectively reviewed 468 patietns with nonatopic asthma or allergic rhinitis without sensitization to 33 aeroallerens out of the 1,596 patients wirh respiratory allergic diseases who visitied Wonju Christian Hospital between June 2005 and July 2007. Nonatopy was determined by negative skin prick test results for all of the aeroallergens. Patients with were excluded from the study total IgE levels of >500 IU/mL because such levels were more frequently associated with other causes. Results: There were 468 patients with nonatopy and total IgE levels of <500 IU/mL (169 males and 299 females). The mean total IgE levels were 41.0 IU/mL in female patients with underweight (BMI<18.5 kg/m2), 64.6 IU/mL in those with normal weight (18.5≤BMI<23 kg/m2), 78.9 IU/mL in those with overweight (23≤BMI<25 kg/m2), and 85.5 IU/mL in those with obesity (BMI≥25 kg/m2). The mean total IgE levels were significantly higher in female patients with obesity or overweight than in those without (83.4 versus 61.8 IU/mL, P=0.036). There were no significant difference in serum total IgE levels according to BMI in male patients. Conclusion: Obesity may be a contributor to increased total IgE levels in female patients with nonatopic respiratory allergy. (Korean J Asthma Allergy Clin Immunol 2011; 31:288-294)
호흡기 알레르기증상으로 강원도의 한 대학병원을 방문한 환자에서 흡입 알레르겐에 대한 감작률
이명규 ( Myoung Kyu Lee ),리원연 ( Won Yeon Lee ),용석중 ( Suk Joong Yong ),신계철 ( Kye Chul Shin ),이선녕 ( Shun Nyung Lee ),이석정 ( Seok Jeong Lee ),이지호 ( Ji Ho Lee ),정세현 ( Sae Hyun Jung ),정예령 ( Ye Ryung Jung ),김상하 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.1
Background: There are some differences in common inhalant allergens among regions in Korea. Gangwon region, including Wonju City, which has a lot of mountains is relatively less urbanized and industrialized. It is necessary to determine which inhalant allergens are common in this region. Objective: This study was conducted to observe the prevalence of sensitization to inhalant allergens in patients visiting a university hospital in Gangwon region and to evaluate the difference in sensitization rates to allergens from other regions in Korea. Method: Skin prick tests were performed with 33 common inhalant allergens on 1,596 patients with respiratory allergic symptoms from June 2005 through July 2007 at a university hospital. Result: The number of positive responders to more than 1 allergen was 609 (38.2%) of the 1,596 patients. The most common offending allergen was Dermatophagoides pteronyssinus (19.5%), followed by Dermatophagoides farinae (17.2%), Tyrophagus putrescentiae (10.1%), Trichophyton (9.5%), rabbit fur (7.8%), mugwort (7.4%), cockroach (6.5%) and orchard grass (4.9%). Conclusion: The most common offending allergen was found to be the house dust mite in Gangwon region. The sensitization rate to mugwort pollen is the highest among pollen allergens, followed by orchard grass pollen. (Korean J Asthma Allergy Clin Immunol 2011;31:27-32)