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경도비만 여성에서 생커피두 엑기스의 섭취에 의한 체지방 감소 효과
김태수 ( Tae Su Kim ),양웅석 ( Woong Suk Yang ),박소이 ( So I Park ),이성표 ( Sung Pyo Lee ),강명화 ( Myung Hwa Kang ),이재환 ( Jae Hwan Lee ),박일범 ( Il Bum Park ),박현준 ( Hyun Jun Park ),무라이히로미치 ( Hiromichi Murai ),오카다타다 한국식생활문화학회 2012 韓國食生活文化學會誌 Vol.27 No.4
In previous studies, we performed joint animal studies and clinical trials between Yonsei University and Oryza Oil & Fat Chemical Co. Ltd. We have shown that coffee bean extract has potent anti-obesity and hypotriglyceridemic activities as well as beneficial effects on body fat reduction.In this study, the effects of coffee bean extract (100 mg/capsule) on body fat reduction were evaluated in overweight/obese women (body mass index of 25~30 kg/m2 or body fat > 30%) not diagnosed with any type of disease. Subjects were randomly assigned to a coffee bean extract group (n=10) or placebo group (n=10). We measured anthropometric parameters, abdominal fat distribution by computed tomography and blood components before and after the 8week intervention period. After supplementation, the coffee bean extract group showed body weight (p=0.08), body mass index (p=0.06), hip circumference (p<0.05), and upper waist circumference (p< 0.01). In addition, after 8 weeks, the coffee bean extract group showed a significant decrease in abdominal internal fat area compared to 0 weeks (0 weeks : 155.8 cm2; 8 weeks : 145.9 cm2, Δ change : -9.9 cm2, respectively). However, there were no significant differences in lipid profiles or serological measurements between the coffee bean extract group and placebo group. The results of our human study demonstrated that coffee bean extract supplementation for 8 weeks has beneficial effects on reducing abdominal internal fat area as well as hip and waist circumferences.