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오원택(Oh Won-Taek),이주상(Lee Ju-Sang),정호발(Joung Ho-Bal) 대한치료과학회 2013 대한치료과학회지 Vol.5 No.1
Objective: This study seeks to establish the benefits of sling exercise on chronic low back pain patients by examining positive changes in their posture, physical functioning and degree of back pain. Method: Six women with Chronic Low Back Pain participated in this study. Three times per week for a period of six weeks the six patients participated in fifty-minute sessions of sling exercise training. The training program consisted of seven different movements. The patients' posture, physical functioning and degree of back pain were measured both pre- and post-training using the 3D Moire Scanner, ODI and VAS. Results: After the six weeks of study, the 3D Moire Scanner showed a decrease in the top of lumbar depth (TLD) in all participants except one patient, and the ODI and VAS results were globally positive. Conclusion: The study results demonstrate that sling exercise does improve posture, physical functioning and that it could indeed be an effective intervention for lumbago.
슬링 운동과 시각적 되먹임을 이용한 안정화 운동이 만성요통환자의 통증, 근 기능 및 척추운동성에 미치는 효과 비교
오원택(Oh Won-Taek),허진강(Hur Jin-Gang),정신호(Jung Shin-Ho) 대한치료과학회 2013 대한치료과학회지 Vol.5 No.2
Objective: This study investigated the comparison of the effects of sling exercise (SE) and visual feedback exercise (VFE) on pain, disability, muscle function, and spinal mobility on chronic low back pain(CLBP). Method: 23 patients with CLBP were randomized into two groups of 11 members in the SE group and 12 members in the VFE group. One group performed SE and the other group performed VFE, each for 50 minutes three times a week for eight weeks. Pain intensity was measured by the Visual Analog Scale(VAS) and the Oswestry Disability Index(ODI). Transversus Abdominis(TrA) endurance was measured by the Pressure biofeedback unit. Spinal mobility was measured by the Spinal mouse. Measurements were made at baseline, and eight weeks after the intervention. Results: Significant differences in VAS and ODI were observed within both groups and SE group experienced a greater decrease in pain and disability. TrA endurance for each group showed significant change eight weeks after the intervention(p<.05). VFE group experienced a greater increase in TrA endurance. Spinal mobility increased for both groups in the lumbar flexion angle, but significant differences were observed the SE group in the lumbar extension angle. Conclusion: SE and VFE were effective in decreasing pain, disability, and increasing TrA endurance and spinal mobility in chronic low back pain patients. SE was more effective in pain, disability, lumbar segmental stabilization while VFE was more effective in TrA endurance.
Olanzapine과 Lithisum 복용 후 나타난 Neuroleptic Malignant Syndrome에 동반된 급성신부전과 Lithium 중독
오원택 ( Won Taek Oh ),맹치훈 ( Chi Hoon Maeng ),박미나 ( Mi Na Park ),최선영 ( Sun Young Choi ),정경환 ( Kyung Hwan Jeong ),문주영 ( Ju Young Moon ),이태원 ( Tae Won Lee ),임천규 ( Cheon Gyu Ihm ),이상호 ( Sang Ho Lee ) 대한신장학회 2006 Kidney Research and Clinical Practice Vol.25 No.5
We report a patient developed neuroleptic malignant syndrome (NMS) with myoglobulinemic acute renal failure and lithium intoxication due to lithium-olanzapine combination, who was successfully treated by hemodiafiltration. A 34-year-old woman with a 14-year history of bipolar disorder had been treated with lithium-olanzapine during last four days. She was admitted to our hospital for muscular rigidity, hyperthermia and altered consciousness. On admission, rhabdomyolsis was demonstratd by biochemical methods and serum level of lithium was 3.78 mEq/L which was far above toxic level. After the diagnosis of NMS with acute renal failure and lithium intoxication, olanzapine and lithium were discontinued and conservative measures and continuous venovenous hemodiafiltration were instituted. She recovered without any neurologic sequelae. (Korean J Nephrol 2006;25(5):835-839)
맥락얼기 뇌실막세포이식이 척수 손상 흰쥐의 신경재생에 미치는 영향
이원택(Won Taek Lee),오형석(Hyung Seok Oh),정효석(Hyo Seok Jeong),김재환(Jae Hwan Kim),안수경(Soo Kyung Ahn),이종은(Jong Eun Lee),박경아(Kyung Ah Park) 대한해부학회 2004 Anatomy & Cell Biology Vol.37 No.6
흰쥐를 대상으로 척수를 완전히 가로절단 또는 둔상으로 손상을 가한 후 손상 부위를 신경원을 재생시킬 수 있다고 생각되는 조직인 맥락얼기 뇌실막세포를 삽입한 다음 기능의 회복이 일어난 실험동물의 척수에 어떠한 형태학적 변화가 오는지를 관찰하고자 본 실험을 시도하였다. 맥락얼기 뇌실막세포 삽입은 최초로 손상을 가한 후 2~3주 후에 실시하였다. 형태학적인 관찰을 하기 위해, H-E, Nissl 염색, 신경세사단백질, 아교섬유산성단백질 면역조직화학염색을 하였고, 실제로 신경의 재생이 일어나 척수 원위부로 자라나는지를 관찰하기 위해 norepinephrine 생합성의 속도제한 효소인 tyrosine hydroxylase와 serotonin을 항원으로 하는 면역조직화학방법을 이용하여 하행섬유가 손상 원위단으로 성장하는지를 관찰하고자 하였다. 맥락얼기 뇌실막세포를 넣어준 척수손상 동물에서는 마비된 뒷다리에 운동이 일어나 회복된 양상이 일부에서 나타났으 며, H-E 염색과 Nissl 염색에서는 손상된 부위가 크게 감소했고, 근위부와 원위부에 모두 정상적인 회색질의 앞뿔신경세포가 나타났다. 백색질도 섬유다발로 이어졌으며, tyrosine hydroxylase와 serotonin 양성신경원이 원위부쪽으로 성장하는 현상을 관찰할 수 있었다. 일부에서는 성상교세포로 분화한 모습도 관찰되었다. Nerve regeneration in the central nervous system has been studied by grafting various tissues and cells. Choroid plexus epithelial cells represent a continuation of ventricular ependymal cells and have the same origin as regarded as modified ependymal cells. To study the use of choroid plexus ependymal cell grafting for nerve regeneration in the spinal cord, the choroid plexus was excised from the lateral and fourth ventricles of adult Sprague-Dawley rats, minced into small fragments, and grafted at the T9 level in adult rat spinal cord transected or contused. In this study, transplants of choroid plexus ependymal cells were successfully used to promote functional and structural recovery after spinal cord transection and contusion. The area of damaged spinal cord was diminished after choroid plexus ependymal cells transplantation. Nearly normal anterior horn cells were observed immediately distal to the transected region. Tyrosine hydroxylase immunoreactive descending fibers were observed in the distal region beyond transected area. These findings indicate that choroid plexus ependymal cells have the ability to facilitate axonal growth, suggesting that they may be a promising candidate as graft for the promotion of nerve regeneration in the spinal cord.