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- 검색키워드
- 저자 : 오동훈(Dong Hoon Oh) (검색결과 149 건)
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정신분열병의 시각자극 사건유발전위 P300에 대한 연구
오동훈,남정현,안동현,김석현,최준호,Oh, Dong-Hoon,Nam, Jung-Hyun,Ahn, Dong-Hyun,Kim, Seok-Hyun,Choi, Joon-Ho 대한생물정신의학회 2004 생물정신의학 Vol.11 No.1
Objective:Event-related potentials(ERPs) are electrical changes recorded at the surface of the scalp in response to stimulus presentation, and their latency and amplitude change according to cognitive processes. Through past studies of the auditory ERP in schizophrenia, the P300 has been reported to be statistically smaller and delayed in schizophrenia than comparison groups. However, studies of the visual ERP have not been systematically examined. The present study was designed to investigate the visual P300 in patients with schizophrenia and normal controls and to compare the pattern of P300 between them. Methods:The subjects were composed of patients(N=22) with schizophrenia by DSM-IV and normal controls(N=22). The visual ERPs were measured by the visual continuous performance test. P300 amplitude and latency measured on 5 scalp electrodes(Fz, Cz, Pz, $T_7$, $T_8$) were compared between patients and controls. Results:The P300 latencies measured on Fz, Cz, Pz, and $T_7$ electrodes were significantly longer in patients than controls(p<0.05). The P300 amplitudes in patients were smaller than controls. However, the difference between them was not statistically significant. Conclusion:Analysis of the visual ERPs showed that the P300 latency is significantly delayed and the P300 amplitude is slightly smaller in patients than controls. These results are similar to established studies of the auditory P300 in schizophrenia.
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안구운동 민감 소실 및 재처리 요법(Eye Movement Desensitization and Reprocessing) 치료 후 국소 뇌 혈류 변화:두 증례의 SPECT 연구
오동훈,최준호,Oh, Dong-Hoon,Choi, Joonho 대한생물정신의학회 2004 생물정신의학 Vol.11 No.2
Over the last decade, EMDR(Eye Movement Desensitization and Reprocessing) has emerged as a promising new treatment for trauma and other anxiety-based disorders. However, neurobiological mechanism of EMDR has not been well understood. Authors report SPECT findings of two patients of PTSD before and after EMDR. Brain 99mTc-ECD-SPECT was performed before and after EMDR treatment. To evaluate the significance of changes in the regional cerebral perfusion, t-test was conducted on the resulting images using SPM99. In addition, clinical scales(CAPS, CGI, STAI) were employed to asses the changes in the clinical symptoms of the patients. After EMDR treatment, each showed significant improvement in clinical symptoms. The cerebral perfusion increased in bilateral dorsolateral prefrontal cortex, and decreased in the temporal association cortex. The differences in the cerebral perfusion between patients after treatment and normal controls decreased. These changes appeared mainly in the limbic area the and the prefrontal cortex. These results suggest that EMDR may show the therapeutic effect through 1) improvement in the emotional control by increased activity in the prefrontal cortex, 2) inhibited hyperstimuli on amygdala by deactivation of the association cortex, 3) inhibition on past trauma related memory, and 4) keeping the functional balance between the limbic area and the prefrontal cortex. This case report needs further replication from studies with larger sample.
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오동훈,이중우,금동호,전성환,김강민,Oh, Dong-Hoon,Lee, Joong-Woo,Keum, Dong-Ho,Jun, Sung-Hwan,Kim, Kang-Min 한국항해항만학회 2006 한국항해항만학회지 Vol.30 No.10
부산항(북항) 재개발사업은 노후화된 북항 일반부두를 해양관광의 중심지역 그리고 부산시민을 위한 친수공간으로 개발하기 위해 그동안 많은 연구와 노력이 진행되어 왔으며, 현재 구체적인 방안이 모색되는 실행단계로 진입하였다. 한편, 재개발로 인한 유동장 및 해수교환의 변화는 환경적인 측면에서 중요한 검토사항 중 하나이다. 본 연구에서는 북항 재개발에 따른 일반적인 자료를 수집 분석하고, 이를 바탕으로 하여 재개발에 따른 유동장의 변화와 만 내 해수교환을 수치실험으로 검토하였다. 실험결과, 조류속 변화는 북항 및 내항에서 감소가 나타나고 주수로상에서 증가가 나타나고 있다. 해수교환 변화는 15일이 지난 준 정상상태에서 재개발 전후 공히 약 77% 내외에 달하는 것으로 나타났다. In connection with redevelopment of Busan North Port, there has been lots of studies and efforts for the development of superannuated North general piers into a center of marine tourism and waterfront for the citizens of Busan. Recently it has moved to the stage of execution, after several trials to find concrete solutions. On the other hand, the change of flow field and tidal exchange cuased by redevelopment is one of the important investigation subjects. This study deals with the change of flow field and water exchange after redevelopment using numerical simulation technique, based on the general data which were collected and analyzed. As a result of simulation, the speed of tidal currents are tended to decrease near the North and inner-port and increase at the main waterway. Furthermore, the tidal exchange had a tendency to be small both before and after redevelopment by about 77% in a quasi steady state, which is about 15 days after.
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오동훈,강영진,정혁,송혜진,조유석,김도진,Oh, Dong-Hoon,Kang, Young-Jin,Jung, Hyuck,Song, Hye-Jin,Cho, You-Suk,Kim, Do-Jin 한국재료학회 2009 한국재료학회지 Vol.19 No.9
Thin films of single-wall carbon nanotubes (SWNT) with various thicknesses were fabricated, and their optical and electrical properties were investigated. The SWNTs of various thicknesses were directly coated in the arc-discharge chamber during the synthesis and then thermally and chemically purified. The crystalline quality of the SWNTs was improved by the purification processes as determined by Raman spectroscopy measurements. The resistance of the film is the lowest for the chemically purified SWNTs. The resistance vs. thickness measurements reveal the percolation thickness of the SWNT film to be $\sim$50 nm. Optical absorption coefficient due to Beer-Lambert is estimated to be $7.1{\times}10^{-2}nm^{-1}$. The film thickness for 80% transparency is about 32 nm, and the sheet resistance is 242$\Omega$/sq. The authors also confirmed the relation between electrical conductance and optical conductance with very good reliability by measuring the resistance and transparency measurements.
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오동훈,양병환,최준호,Oh, Dong-Hoon,Yang, Byung-Hwan,Choi, Joonho 대한생물정신의학회 2007 생물정신의학 Vol.14 No.4
Recent researches have shown that important cellular-based autoprotective mechanisms are mediated by heat-shock proteins(HSPs), also called 'molecular chaperones'. HSPs as molecular chaperones are the primary cellular defense mechanism against damage to the proteome, initiating refolding of denatured proteins and regulating degradation after severe protein damage. HSPs also modulate multiple events within apoptotic pathways to help sustain cell survival following damaging stimuli. HSPs are induced by almost every type of stresses including physical and psychological stresses. Our nervous system in the brain are more vulnerable to stress and damage than any other tissues due to HSPs insufficiency. The normal function of HSPs is a key factor for endogenous stress adaptation of neural tissues. HSPs play an important role in the process of neurodevelopment, neurodegeneration, and neuroendocrine regulation. The altered function of HSPs would be associated with the development of several neuropsychiatric disorders. Therefore, an understanding of HSPs activities could help to improve autoprotective mechanism of our neural system. This paper will review the literature related to the significance of HSPs in neuropsychiatric field.
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[論文]주택건설업의 중장기 경쟁력 제고를 위한 개발금융기법 비교
오동훈(Dong-Hoon Oh),송승호(Sang-Ho Song) 한국주택학회 2005 주택연구 Vol.13 No.2
본 연구는 선분양에서 후분양으로 주택분양제도가 전환되어 갈 것에 대비하여 국가 경제의 중요한 축인 주택건설업계 입장에서 자금조달기법이 가자는 장단점을 검토하고 적정한 개발금융기법을 선택·활용할 수 있는 기준을 제시하며 동 기준으로 개발금융 가합들을 비교 · 분석하는 것을 목적으로 한다. 연구의 주요결과를 통해 주택건설업계에 서는 개발금융의 비교기준인 자금조달의 용이성, 자금조달원의 안정성, 프로젝트의 성 공가능성, 금융비용, 프로젝트의 종류, 프로젝트의 규모에 따라 각 개발금융기법을 활용 하는 때에, 자사의 상황과 또한 프로젝트의 상황별로 각 개발금융을 이용해야 한다. 특히 개발금융을 실제로 활용하여 사업을 진행시키는 주택건설업계의 업장에서 자금조달 기법을 비교하고, 주택건설업계가 선택·활용할 수 있는 개발금융기법을 제시하여 정부 가 개발금융을 도입할 때도 활용주체인 주택건설업계의 입장을 고려해야 함을 보여주었다. This study aims on finding a way for housing construction industry, which is an important circle of national economy, to get ready for the future through examining strength and weakness development financing technique has from the view of housing construction industry preparing for a change from pre-sale to post-sale on housing development finance system. Also, it proposes standards to choose and utilize a suitable raising fund technique. Through main results of the study, housing construction industry should use each development financing by condition of a company and a project at the time each development financing technique is utilized according to comparing standards of development financing, which are easiness of raising fund, stability of funding source, possibility to succeed on a project, financing cost, project type, and project size. Especially, it showed that standpoint of housing construction industry, which is the subject of utilization, should be considered even on induction of development financing by government while examining strength and weakness of development financing technique from the standpoint of housing construction industry, which utilizes development financing practically to proceed its business, and showing a development financing technique, which housing construction industry can choose and utilize.
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오동훈(Oh Dong-Hoon),권영섭(Kwon Young-Sup) 한국주택학회 2008 주택연구 Vol.16 No.3
본 연구의 목적은 현행 리모델링 관련 법제도 완화 적용의 문제점을 실제 사례조사를 통해 분석한 후 바람직한 법제도의 완화적용 방향을 제시하는 한편 아직도 정비나 개선이 되지 못한 법제도를 검토하여 리모델링의 활성화를 위한 개선방안을 제시하는 데 있다. 그 동안 본 연구에서는 공동주택 리모델링이 법제도에 도입된 이후 공동주택 리모델링 활성화를 위한 정책은 선행연구들에서 주장된 대로 지속적으로 법제도를 완화하여 왔으나 본 연구는 리모델링으로 인한 주거환경 및 도시환경에의 영향도 함께 고려함으로써 거주자의 삶의 질 향상에도 기여할 수 있는 공동주택 리모델링의 방안을 찾아보고자 함으로써 기존연구와의 차별성을 보이고 있다. 리모델링 관련 법규 적용 실태사례조사를 위해 일시에 리모델링이 많이 진행된 곳으로 잘 알려진 서울시 용산구 이촌동 지역에서 해당 구청에 2006년 공동주택 리모델링을 위한 법 적용 완화를 위한 건축심의가 신청되었던 H, S, T, V, J 아파트 등 5개 아파트단지를 조사하였다. 공동주택 리모델링 활성화를 위해 본 연구에서는 1) 주거전용면적의 증축 범위에 대한 한계 설정, 2) 일조 확보를 위한 높이제한 기준의 완화범위 설정, 3) 일부 기존 棟의 이전 및 개축 허용, 4) 세대수 증가 허용, 5) 공동주택 층고기준 완화 등을 개선방안으로 제시하였다. The purpose of this study is firstly to present the desirable direction of the remodelling related law and policy after analyzing the mitigation problems of the current law and policy through case studies and secondly to show the improvement schemes for vitalizing apartment remodelling by reviewing the law and policy which have not been reorganized and reformed. According to many preceding studies, since the apartment remodelling law had been introduced, the vitalization policies on apartment remodelling have been continuously relaxed. However, this study is distinguished from other preceding studies because it considers influences on the residential and civil environment by remodelling and it seeks for improvement schemes of apartment remodelling which could contribute to living quality of residents. The area of a case study used in this paper for the application of remodelling law is Ichon-dong, Yongsan-gu, Seoul where many remodelling projects had performed simultaneously. This study focuses on five apartments such as H, S, T, V, J apartments which are applied to the Yongsan-gu District Office for a building deliberation in order to get a mitigating decision by the remodelling law in 2006. As the research result, the improvement schemes for vitalizing apartment remodelling are 1) an establishment of the limit on living space"s extension, 2) an establishment of the relaxation range on a height limit for a right to enjoy sunshine, 3) a permission to partially relocate and rebuild the existing apartments, 4) a permission to increase the number of households, and 5) a relaxation on apartment floor limit.
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