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오갑진(Gab-Jin OH) 조선대학교 지식경영연구원 2010 기업과 혁신연구 Vol.3 No.1
본 연구는 미국의 NASDAQ 주식시장을 구성하고 있는 개별기업들의 자료를 활용하여 개별기업들간 복잡한 연결구조를 체계적으로 검증하는 것이 목적이다. 검증결과의 신뢰성을 높이기 위하여 다양한 측면에서 검증방법을 채택하여 분석하였다. 특히 실제 자료에서 구해진 주식네트워크 구조의 특성을 관찰하기 위해서 개별주식의 평균과 분산 속성만을 반영한 막걷기 (random walk) 자료와 시계열의 비선형성이 제거된 자료를 함께 사용하였다. 검증결과에 의하면, Mantegna에 의해서 소개된 최소신장트리 (minimal spanning tree, MST) 방법에 의해서 도출된 주식간 연결구조는 random network와는 상이한 특성을 가짐을 관찰할 수 있었다. 즉, 다른 주식과 많은 연결개수를 가지는 주식들 (Hub)이 존재함을 관찰하였다. 그리고 이론자료에 의해 생성된 주식네트워크는 연결개수 분포의 관점에서 random network와 매우 유사한 특성을 관찰할 수 있었다. 즉, NASDAQ 주식시장에서 관찰된 주식들간의 복잡한 연결구조는 비선형성이 기인함을 확인할 수 있었다. We investigate the complex connection structure among individual stocks listed on the NASDAQ stock market. We use 818 individual stocks listed on the NASDAQ stock market from 2001.01.03 to 2008.12.30, artificial data sets such as random data generated with mean and variance of original return time series and surrogate data removed the non-linearity from original data in order to increase the reliability of observed results. We found that the degree distribution of the stock network constructed by the minimal spanning tree (MST) method proposed by Mantegna et al. (1998) was very different features from that for an artificial data sets. Therefore, our results argue that the complex properties of MST can be attributed to the non-linearity observed in the financial time series.
정선채,황방연,오갑진,강신정,김미정,최우회,이경순,노재섭,Chung, Sun-Chae,Hwang, Bang-Yeon,Oh, Gab-Jin,Kang, Shin-Jung,Kim, Mi-Jeong,Choi, Woo-Hoi,Lee, Kyong-Soon,Ro, Jai-Seup 한국생약학회 1999 생약학회지 Vol.30 No.3
Seven compounds were isolated from the n-BuOH extract of the dried stem barks of Rhus javanica L. On the basis of physico-chemical, spectroscopic evidences and comparison with authentic samples, the compounds $1{\sim}7$ were identified as gallic acid (1), methyl gallate (2), scopoletin (3), scopolin (4), $1,\;2,\;3,\;4,\;6-penta-O-galloyl-{\beta}-D-glucose$ (5), orcinol (6) and $orcinol-{\beta}-D-glucoside$ (7). Among these compounds, scopolin, $orcinol-{\beta}-D-glucoside$ were isolated from this plant for the first time.
박시경(Si Kyung Park),오갑진(Gab Jin Oh),배춘일(Choon Il Bae),김종현(Hyun Jong Kim),환완식(Wan Sik Han),정순간(Sun Gan Chung),조의환(Eui Whan Cho) 대한약학회 1997 약학회지 Vol.41 No.6
In our search for bioactive natural products with antitumor activity, we have valuated various extracts of Saururi Herba (Saururaceae), which has been used in traditional medicine for edema, beriberi, jaundice, turbid urine, carbuncle and furuncle. The hexane extract of the aerial part of this plant was found to show a potent cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A549, HCT15, SKOV3, HEP-3B) in vitro. Using cytotoxicity-guided chromatographic separation of the hexane extract, cytotoxic constituent: 10-aminomethyl-3-hydroxy-4-methoxyphenanthrene-carboxylic acid lactam, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.
박시경(Si Kyung Park),오갑진(Gab Jin Oh),김현태(Hyun Tae Kim),김현종(Hyun Jong Kim),정순간(Sun Gan Chung),조의환(Eui Hwan Cho) 대한약학회 1998 약학회지 Vol.42 No.3
For the investigation of bioactive natural products with analgesic activity, we have evaluated various extracts of Saururi Herba (Saururaceae), which has been used in traditional medicine for edema, beriberi, jaundice, turbid urine, carbuncle and furuncle. The diethylether extract of this plant was found to show a significant analgesic effect on writhing syndrome in mice. Using bioactivity-guided separation of the diethylether extract, analgesic constituent, (8S, 8`R, 7R, 6`R)-2`-oxo-4,5: 4`,5`-bis(methylenedioxy)-delta1,3,5,3`-8.8`, 7.6`, 2.O.5`-neolignan(sauchinone) was isolated and structurally identified by physico-chemical properties and spectroscopic evidences. This compound has good analgesic activity with lower toxicity, as compared to other antipyretic-analgesic drug(acetaminophen).
김현종(Hyun Jong Kim),김현태(Hyun Tae Kim),배춘일(Choon Il Bae),오갑진(Gab Jin Oh),박시경(Si Kyung Park),정순간(Sun Gan Chung),조의환(Eui Hwan Cho) 大韓藥學會 1997 약학회지 Vol.41 No.6
For the investigation of bioactive natural products with hypoglycemic effect, we have evaluated various extracts of Pulsatillae Radix(Ranunculaceae), which has been used in traditional medicine for hematochezia due to intense evil heat, malaria, chills and fever, epistaxis and internal hemorrhoids. The ethylacetate extract of the radix of this plant was found to show a significant hypoglycemic effect on alloxan diabetogenic mice. Using bioactivity-guided chromatographic purification of the ethylacetate extract, hypoglycemic constituent: 2beta, 3beta, 14alpha, 20,22R, 25-hexahydroxy-cholest-7-en-6-one was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.
배춘일(Choon Il Bae),공재명(Jae Myung Gong),오정완(Jung Wan Oh),김현종(Hyun Jong Kim),오갑진(Gab Jin Oh),박시경(Si Kyung Park),정순간(Sun Gan Chung),조의환(Eui Hwan Cho) 大韓藥學會 1997 약학회지 Vol.41 No.5
To find out antitumor active principles from natural resources, we have evaluated various extracts from the leaves of Alnus hirsuta (Betulaceae). The ethylacetate extract of this plant was found to show a significant cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A5 49, HCT15, SKOV3, HEP3B) in vitro. Using cytotoxicity-guided chromatographic purification of the ethylacetate extract, cytotoxic constituent:1,7-bis-(4-hydroxyphenyl)-5-(beta-D-glucopyranosyloxy)-3-heptanone, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.