쥐 실험을 통한 광노화 피부에 대한 원적외선 효과

예춘정(Chun-Jung Yea),이태종(Tae-Jong Lee) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.8

본 논문은 원적외선의 피부 노화에 대한 개선 효과를 확인하기 위하여 UVB 조사된 쥐를 활용하여 원적외선의 피부 개선 효과를 연구하였다. 실험은 정상군, 대조군, 양성대조군, 실험군1, 실험군2로 조사 그룹을 구성하여 진행하였다. 원적외선 조사는 보미라이 원적외선 마스크를 1일 1회, 주 6일, 4주간 사용하였다. Mexameter를 이용한 멜라닌 지수 측정에서는 양성대조군과 원적외선 조사군은 대조군에 비해 유의하게 낮았고, 현미경 관찰에서 원적외선 조사군은 대조군에 비해 멜라닌생성 정도와 S-100 단백질 발현 정도가 현저하게 줄어들었음을 확인하였다. 이는 피부 조직학적으로 멜라닌 색소 층과 멜라닌 세포수가 감소하여 확연한 미백효과를 보였다. H&E 염색 결과 대조군의 표피에서 Lymphocyte, Monocyte의 증가와 진피 비후도가 두껍게 나타났으나, 양성대조군과 실험군의 관찰 결과 원적외선으로 피부 조직손상 회복도가 정상군에 가깝게 개선되었음을 알 수 있다. Trichrome 염색 결과 피부 조직의 콜라겐 섬유들이 규칙적으로 발달 되어 있고 피부 소엽 주변의 교원섬유가 청색으로 염색되어 정상군의 염색 정도와 가까워 실험군에서 교원섬유의 비후도가 많이 줄어들었음을 알 수 있다. 본 실험 근거로 원적외선은 광노화에 대한 피부 개선 효과가 있음을 알 수 있다. This study was conducted to investigate the beneficial effects of far infrared on skin aging. Animals were divided into five groups, that is, normal (N), control (C), positive control (PC), experimental 1(E1), and experimental 2(E2) groups. Far infrared was applied daily using a BOMIRAI far infrared mask six times a week for four weeks. Melanin indices determined using a Mexameter were significantly lower in the PC and E1 groups than in the control group, and melanin production and S-100 protein expression were significantly lower in the E1 group than in the control group. H&E staining showed greater lymphocyte and monocyte numbers and dermal thicknesses in the C group than in the PC and E1 groups, and in the E2 group skin tissue damage recovered to almost that observed in the N group. Furthermore, trichrome staining showed that collagen fibers in skin tissues were regular and those around skin leaves were dyed blue in the E1 and E2 groups and similar to that observed in the N group. In addition, collagen fiber fibers levels were significantly lower in the E1 and E2 groups than in the C group. Our results suggest far-infrared rays have beneficial effects on photoaged skin.

노인들의 외모관리행동이 외모만족 및 자아존중감에 미치는 영향

예춘정 ( Chun Jung Yea ) 한국노인의료복지학회 2010 노인의료복지연구 Vol.2 No.2

The study aimed to identify the influence of appearance management behaviors, satisfaction with physical appearance and in elder people on self esteem through the analysis of structure model. Quantitative data, from 342 people over sixty years of age living in Daegu was collected. Major findings were as follows; 1) There were difference m appearance satisfaction in terms of skin and hair care and in self esteem in terms of weight management, hair care and clothing behavior. An analysis of the data revealed the more people got skin and hair treatments the higher ,was. Also, the more people did weight management, hair care, clothing behavior and the more people had appearance satisfaction, self esteem increased. 2) To summarize the effects of variables in self esteem, appearance satisfaction was the most highly affected, followed by clothing behavior and weight management.

간 손상으로 유도된 랫드에서 MSE가 활성 변화와 분자생물학에 미치는 영향

예춘정(Chun-Jung Yea),이태종(Tae-Jong Lee) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.2

본 실험은 건강기능식품의 원료로 이용되고 있는 식품들을 혼합하여 열수 추출한 추출물(시료추출물, MSE)이 간 손상의 예방 및 치료와 관련된 건강기능성 영양식품으로서의 활용 가능성을 확인하고자 사염화탄소에 의한 랫드의 간 손상을 간경화 수준의 60%로 유발시켜 추출 물질의 투여에 따른 간 질환 개선에 미치는 영향을 분석하였다. 혼합수추출물(MSE)의 용량은 군별 다르게 투여 하여(0.50ml, 0.75ml), 간 손상된 랫드에 미치는 생리활성 기능과 생화학적 기능 및 분자생물학적 TGF-β, P53을 측정하여 혼합추출물의 투여 후 기능 변화를 분석 하였다. 실험은 정상군, 대조군, 양성대조군, 실험군1, 실험군2 군으로 하여 군당 6마리씩 총 30마리를 이용하였고, 지정된 용량으로 1일 1회 일정한 시간대에 주 6회씩 6주간 적용 후 처치하였으며, 실험 결과는 정상군과 양성대조군에 비하여 대조군에서는 통계적으로 유의성 있게 높았으며, 실험군(1, 2)에서는 대조군에 비해 통계적으로 유의성 있게 낮아졌으며, 정상군과 양성대조군 비교에서도 실험군과 유사한 결과가 나타났다. 실험군(1, 2) 간 비교에서 유의한 차이는 일부 있었으나 유의성 있는 많은 변화가 나타나지 않았다. 이상의 실험결과를 종합해 보면 기능성 식품으로 활용 가능성이 있을 것으로 판단되고 생리활성 변동과 간 분자생물학적 발현 정도를 동일 분야 연구에 활용이 될 것으로 사료 된다. The purpose of this experiment is to investigate the feasibility of extracts (sample extract, MSE) mixed with hot - water extracts as health functional nutritional foods for prevention and treatment of liver damage. The experimental method was to investigate the effects of carbon tetrachloride on liver damage in rats by 60% of liver cirrhosis level. The effect of mixed extracts (MSE) was investigated by measuring the physiological functions, biochemical functions, and molecular biologic TGF - β and P53 levels in liver - injured rats. with MSE doses administered differently(0.50ml, 0.75ml). A total of 30 rats were used for normal group, control group, positive control group, experimental group 1, and experimental group 2. The rats were given 6 times a week for 6 weeks at a fixed time once a day. The results of the experiment were statistically significantly higher in the control group than in the normal group and the positive control group, and statistically significantly lower in the experimental group (1 and 2) than the control group. There were some significant differences in the comparison between the experimental groups (1 and 2), but no significant changes were found. In conclusion, the results of this study are expected to be useful as functional food, and the variation of physiological activity and the degree of liver molecular biotechnology will be used for the research of the same field.

6종 식품의 혼합추출물이 사염화탄소로 유도된 흰쥐 간 손상에 미치는 보호효과

황보미향,예춘정,Hwangbo, Mi-Hyang,Yea, Chun-Jung 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.6

The objective of this study was to examine the biochemical parameters of hepatic function such as serum level of ALT (alanine aminotransferase), AST (aspartate aminotransferase), ALP (alkaline phosphatase), LDH (lactate dehydrogenase), and content of TG (triglyceride) and cholesterol, and tissue immunological changes of the $CCl_4$-treated rats with administration of the mixed sample extract (MSE). The liver weight in $CCl_4$-administered experimental control group (EC) was slightly higher than that of normal control (NC) group. Hepatic damage parameters (ALT, AST, ALP, LDH & TG) in serum of the EC group were significantly higher than those in serum of the NC and silymarin-treated positive control (PC) group. On the other hand, these hepatic damage parameters of MSE-treated experimental (E1 & E2) groups were significantly lower than those of EC group. The number of WBC, neutrophils, lymphocytes and platelets, and the contents of hemoglobin, and hematocrit in EC group were significantly higher than those of NC group. However, the number of WBC and lymphocytes in E1 and E2 groups were significantly lower than those of EC group. Also, the collagen developmental areas in the liver of NC and PC groups by hepatic immuno-histological findings were found slightly positive. Whereas, hepatic fibrous developmental tissue of EC group was strongly positive brown color band, those of E1 & E2 groups were decreased. Therefore, it was concluded that the induction of hepatic fibrous tissue activation had a preventive effect of MSE against the $CCl_4$-induced hepatic damage in rats. However, further study is needed in this filed.

후두 손상 유발시킨 랫드에 칡잎추출물을 투여하여 스트레스 경감효과에 미치는 영향

이태종,예춘정,Lee, Tae-Jong,Yea, Chun-Jung 한국환경보건학회 2012 한국환경보건학회지 Vol.38 No.5

Objectives: This study aims to investigate the effects of voice disorders on changes in stress among people with damaged larynxes. To accomplish this, physiological changes and reductions in the stress of Sprague-Dawley rats whose larynx had been damaged were investigated after the laboratory animals were administered kudzu leaf extracts with sedative effects. Methods: In the experiment, a total of 24 rats were divided into four groups of six rats, including the normal group, control group, experimental group 1, and experimental group 2. After orally administering to the subjects a predetermined amount of the extract at a specific time (once per day over five weeks), changes in physiological functions, internal organ weight, cortisol, estrogen, and progesterone in the subjects were examined, and an immunological test was conducted on their brain tissues. Results: Statistical significance was seen in the experimental group as opposed to the control group and the results were similar to those of the normal group. Conclusions: In consideration of these results, it is deemed that there are severe effects on stress due to voice disorders and that the administration of kudzu leaf extracts results in improvement in stress.

후두 손상으로 스트레스 유발시킨 랫드에 칡잎추출물을 투여 후 항산화작용과 뇌 조직에 미치는 영향

이태종(Lee, Tae-Jong),예춘정(Yea, Chun-Jung) 한국산학기술학회 2013 한국산학기술학회논문지 Vol.14 No.12

본 연구는 후두 손상 후 목소리 장애로 인해 스트레스변화에 미치는 영향을 알아보고자 SD계 랫드에 후두 손상을 유발시킨 후 실험동물에서 나타나는 변화와 스트레스 경감효과에 미치는 영향을 진정작용이 있는 칡잎추출물 을 투여 후 변화를 보고자 하였다. 실험은 정상군, 대조군, 실험군(1, 2)으로 하여 군당 6마리씩 총 24마리를 이용하 였고, 지정된 용량으로 1일 1회 일정한 시간대에 주 6회씩 5주간 경구투여 후 항산화실험과 분자화학적 검사를 하였 다. 결과는 정상군에 비하여 대조군에서는 통계적으로 유의성 있게 높았으며(p<0.05), 실험군에서는 대조군에 비해 통 계적 유의성 있게 낮아져(p<0.05), 정상군보다도 좋게 나타났다. 실험결과를 종합해 보면 칡잎추출물은 대조군과 비교 할 때 통계적으로 유의성 있는 변화를 확인하였다. 따라서 칡잎추출물 투여 시 스트레스 경감효과에 효과가 있는 것 으로 사료된다. To examine the effects of voice disorders after a laryngeal injuryon the changes in stress, this study examined the effects of the changes observed in laboratory animals and on stress reduction effects, by inducing a laryngeal injury in SD type rats after administering a kudzu leaf extract, which has a sedation effect. For testing, a total of 24 rats comprising the normal group, control group and experimental groups (1 and 2 6 rats in each group) were used, and antioxidant experiments and molecular and chemical tests were conducted by administering a specified amount of kudzu teaorally once a day at a set time, 6 times per week for 5 weeks. The control group appeared to be significantly higher (ed note: What is higher?) than the normal group (p <0.05), whereas the experimental group showed significant decreases compared to the control group (p <0.05), showing a better result than the normal group. The test results showed that the kudzu leaf extract resulted in significant changes compared to the control group. Overall, the administration of kudzu leaf extract has stress reduction effects.

일부전문대학생의 학교생활만족도와 자아존중감에 영향을 미치는 요인

오선영 ( Sun Young Oh ),예춘정 ( Chun Jung Yea ),신동숙 ( Dong Sook Shin ) 한국노인의료복지학회 2014 노인의료복지연구 Vol.6 No.2

The objective of this study is to aimat improving college students` loyalty in college life by analyzing various factors that affect self-esteem scale and satisfaction of college life and boosting their satisfaction. The analysis revealed that general characteristic of students and college students` self-esteem have a close relationship with age, allowance, religion, part-time job, satisfaction of major, club activity, friendship, and importance of college life. Furthermore, the general characteristic of students and college life satisfaction are attributed to major in college life, college rules in residency, and welfare facilities in age. The self-esteem and college life satisfaction for those, who have allowance and religion, have strong relationship with part-time job. The psychological and economical factors play a major role in college students` life in college.

간호사의 직무요구,직무자원,감정노동 및 감성지능이 소진에 미치는 영향

안정아(Ahn Seong Ah),예춘정(Yea Chun-Jung),염동문(Yeum Dong Moon) 경성대학교 사회과학연구소 2011 社會科學硏究 Vol.27 No.4

본 연구는 종합병원에 근무하는 임상간호사를 대상으로 간호사의 직무요구-자원, 감정노동 및 감성지능이 소진에 미치는 영향 규명함으로서 간호사의 소진감소를 위해서 간호사의 감성지능증진 교육의 중요성을 제시하고자 실시하였다. 모형에서 각각의 경로계수들을 통하여 경로들이 유의미한지를 알아본 결과 감성지능에 유의미한 요인은 직무요구, 직무자원, 감정노동이었고 소진에 유의미한 요인은 직무요구, 직무자원, 감성지능으로 직무요구가 낮을수록, 직무자원이 높을수록 감성지능이 높아지고,직무요구가 높을수록, 직무자원과 감성지능이 낮을수록 소진이 높아지는 것을 알 수 있었다. 소진에 대한 변인들의 효과에서는 직무요구가 가장 큰 효과를 보였고, 다음이 직무자원, 감정노동, 감성지능 순으로 나타났다. 이 중 직무요구, 직무자원 및 감정노동은 감성지능에 의해 소진이 높고 낮음이 나타나 감성지능이 조절효과로 작용하였다. 따라서 본 연구의 이러한 결과로부터 간호사의 소진을 감소시키기 위해서는 직무요구, 직무자원 및 감정 노동에 대한 중재가 필요하며, 이러한 변인에 영향을 미치는 간호사의 감성지능을 관리할 수 있는 중재프로그램개발이 필요하다고 결론을 내릴 수 있다. The purpose of the study was is to identify the intervening effect of emotional intelligence in the process of burnout affected by job demands, job resources and emotional labor of nurses. The participants were 238 nurses working at general hospitals in J-city, Korea. The data was collected through a structured questionnaire from November 4 to 30, 2009 and analyzed using SPSS/Win 18.0 and AMOS 18.0.Reportedjobdemands,job resources and emotional intelligence had observed to have a significant direct and indirect effect on meaning in burnout. In addition, job demands, job resources and emotional labor had a significant indirect effect on meaning in burnout. Job demands were the most influential factor, and all of these variables explained 54% of the variances in meaning in burnout among the nurses. The findings from this study of job demands, job resources and emotional labor had intervening effects on burnout by emotional intelligence. Therefore, in this study the effect of emotional intelligence was identified.

소목 추출물에 의한 모발의 염색특성에 관한 연구

황종호 ( Jong Ho Hwang ),예춘정 ( Chun Jung Yea ) 대한미용학회 2007 대한미용학회지 Vol.3 No.1

일부지역 여성과 피부건강관리 실천행위와 관련요인

김성복,예춘정 한국미용학회 2001 한국미용학회지 Vol.7 No.2

This study was conducted to provide basic data for women' s practice of skin health care. The subjects of this study were 272 women in Pohang City whose age was above 20 years old. The data were collected from April 24, 2001 to May 9, 2001. In order to examine general characteristics of the subjects and factors which influenced practice of skin health care, the data were analyzed through factor analysis, t-test, ANOVA, and correlation analysis. The results of this study can be summarized as follow, 1. Those whose income was high and those who had experienced receiving professional skin care practiced professional skin care. The rate of practicing skin care for beauty was high in the groups of older women, married women, and women who experienced professional skin care. The rate of practicing obesity control was high in the groups of fat women, and women who experienced professional skin care. Those who experienced professional skin cwe showed high rate of practicing wrinkle care. Those who had the type of compound face skin displayed highest rate of practicing wrinkle care. Those who experienced professional skin care were more concerned about diversion and stress relief. The rate of basic skin care was high in the groups of 'middle-aged' , 'higher income' , 'married' , and staving experience in professional skin care . Those whose face skin were in bad health condition neglected basic skin care more Than those whose face skin were in good health condition, 2. According to the relation between the condition of skin health and the practice of skin care, the practice of basic skin care showed positive correlation (r=0.132), while the practice of skin care for beauty displayed negative correlation (r=-0,119). The other factors related to practice of skin care did not show significant relation with the condition of skin health. All factors related to the practice of skin care revealed significant relation one another, Among the factors, the level of relation between practice of regimen and practice of body shape care was highest. That is, the more they practiced regimen, the more they practiced body shape care. Practice of professional skin care showed high relation with practice of skin care for beauty. The more they practiced professional skin care, the more they practiced skin care for beauty. The most important variable for health promotion is health behavior. In this study, it appeared that the women practiced skin health care through regimen and exercise. In addition to face skin care, basic skin care, and simple total beauty care, it is necessary for them to take strategies for total body care, professional skin care, and holistic beauty care.