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      • 최대하 운동시 온도변화에 따른 운동복 형태가 인체에 미치는 영향

        김광희,어현선 仁荷大學校 스포츠科學硏究所 1999 論文集 Vol.11 No.-

        This study is aimed at finding out the effect of environmental temperature and uniform style on physiological responses by analysing variations of human temperatures(rectal temperature, mean skin temperature), perspiration(total perspiration, partial perspiration), heart-rate, oxygen intake depending on variations of environmental temperatures(each 50% RH per 25℃, 30℃, 35℃) and uniform styles(long sleeve, half-sleeve) during the long time(40min) sub-maximal exercise(50% V02max) This experiment was performed on the subjects of 6 male university students by using the bicycle ergometer. The change of human temperature and heart rata were measured by the interval of 10 minutes during exercise. The total perspiration was measured by the difference of weight before/ after exercise, and the local perspiration by the difference of its filter's weight before / after exercise after a filter of 2.5cm diameter was attached on the back and the femoral. The oxygen intake was measured by collecting aerobic gas for final one minute by the interval of 10 minutes during exercise, and then analysing gas. The experimental results are as follows. 1. The skin temperature increased in proportion to the environmental temperature, and the rectal temperature continuously increased from at the beginning of exercise, and no meaningful difference was by uniform styles. 2. Perspiration increased in proportion to the environmental temperature, no meaningful difference was by uniform style, and there was more perspiration in the back than in the femoral. 3. Heart rate fast increased after exercise, and then gradually increased from after 10 minutes, increased in proportion to the environmental temperature, and no meaningful difference was by uniform styles. 4. The volume of oxygen intake fast increased early exercise, and then gradually increased up to 30 minutes, and was prone to keep in the constant level or decrease, and no meaningful difference was by environmental temperatures or uniform styles. There generally was the meaningful difference by environmental temperatures under most conditions by the results above, but no meaningful difference was by uniform styles. Considering this results, under the intensity of exercise (50% V02max), the variation of environmental temperatures(25℃,30℃,35℃) influenced on physiological responses, whereas the variation of uniform styles did not influence on physiological responses.

      • SCOPUSKCI등재

        한국인 상염색체 우성 다낭신 가계에서의 유전자 아형분석

        한진석,이정상,황영환,김연수,이은주,황대연,이중건,김성권,안규리,어현선,채희진,조종태 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.4

        Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease in adults, and its major morbidities are renal failure and cerebrovascular accident. The prevalence of this disease in the chronic haemodialysis patient population is known to be approximately 2% in Korea. So far, three genetic loci have been identified as being responsible for ADPKD, and approximately 85% of the cases in Western countries are related to the PKD1 gene. However, little information is available concerning the pattern of linkage analysis or the mutations present in Asian populations. For this study, 35 families with hereditary renal cysts were recruited from our ADPKD clinic from 1993 to the present, and their molecular genetic characteristics were studied. Subjects were chosen according to the criteria of Ravine et al. Linkage analysis was done with microsatellite makers(PKD1:SM7, UT581, AC2.5, KG8, D16S418, PKD2: D4S423, D4S1534, D4S1542, D4S1544, D4S2460). Genomic DNA PCR and PAGE gel run were done, and the allele patterns were compared with sonographic findings. The results of this study showed that the ratio of PKD1 to PKD2 was 23:3, and PKD2 families showed the tendency of milder renal prognosis than PKD1 families. In conclusion, we confirmed the usefulness of linkage analysis for ADPKD in Korean population, and aur data shows a similar percentage of PKD1(88%) and PKD2(12%) in Korean patients as in the Western population.

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